Serous fluids and washings: morphological and immunohistochemical patterns in reactive and neoplastic conditions Prof. Ben Davidson, MD PhD, Department of Pathology, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway; Dr. Gareth Rowland, MB, BCh, FRCPath, University Hospital of Wales, Heath, Cardiff, UK
23
Embed
Serous fluids and washings: morphological and immunohistochemical ... · PDF fileSerous fluids and washings: morphological and immunohistochemical patterns in reactive and neoplastic
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
Serous fluids and washings: morphological and
immunohistochemical patterns in
reactive and neoplastic conditions
Prof. Ben Davidson, MD PhD, Department of Pathology, Norwegian Radium Hospital, Oslo
University Hospital, Oslo, Norway; Dr. Gareth Rowland, MB, BCh, FRCPath, University Hospital of Wales, Heath, Cardiff, UK
Disclosure/ Acknowledgement
Serous effusions
• Frequent clinical finding
• Pleural, peritoneal, pericardial
• May be the first presentation of malignancy or only site of
metastasis
• Far-reaching clinical implications
The main questions
• Is it benign or malignant?
• If benign, can we reach a specific diagnosis?
• If malignant, is it primary or metastatic? Diagnosis?
Differential diagnosis
• Primary tumors
Malignant mesothelioma
Primary peritoneal carcinoma
Hematological cancers
Sarcoma (rare)
• Metastases
Carcinomas
Other
Depending on
• Age and gender
• Previous history
• Other clinical findings
• Geography
Differential diagnosis
Davidson, Firat, Michael (eds.), Serous Effusions – Etiology, Diagnosis, Prognosis and Therapy (Springer 2011)