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Improving Cognitive Function Restoring amino acid levels can help improve mental alertness. Restore Nervous System Balance Replace the key neurotransmitters required for daytime nervous system function. Safe & Effective Clinically proven ingredients that are Generally Recognized as Safe. Order Today To register an online ordering account please visit: www.medicalfoodorders.com Amino Acids The fuel the nervous system needs WR RSHUDWH HIƓFLHQWO\ Patented Technology that improves the uptake and conversion of amino acids to neurotransmitters. Sentra AM ® Targeted Medical Pharma Connecting Nutrition to Medicine For the Dietary Management of Fatigue and Cognitive Disorders ! Amino Acid Based Natural and Non-Habit Forming Clinically Effective at Improving Fatigue Generally Recognized as Safe Ingredients
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Sentra AM: Safely Manage Fatigue and Cognitive Disorders

Apr 15, 2017

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Page 1: Sentra AM: Safely Manage Fatigue and Cognitive Disorders

Improving Cognitive FunctionRestoring amino acid levels can help improve mental alertness.

Restore Nervous System BalanceReplace the key neurotransmitters required for daytime nervous system function.

Safe & EffectiveClinically proven ingredients that are Generally Recognized as Safe.

Order TodayTo register an online ordering account please visit: www.medicalfoodorders.com

Amino AcidsThe fuel the nervous system needs

Patented Technologythat improves the uptake and conversion of amino acids to neurotransmitters.

Sentra AM®

Targeted Medical PharmaConnecting Nutrition to Medicine

For the Dietary Management ofFatigue and Cognitive Disorders

!

Amino Acid Based Natural and Non-Habit Forming

Clinically Effective at Improving FatigueGenerally Recognized as Safe Ingredients

Page 2: Sentra AM: Safely Manage Fatigue and Cognitive Disorders

Sentra AM® Product Information 2

Improving Fatigue and Cognitive Disorders

Improving Daytime Fatigue

Reduction in Symptoms of PTSD

PCL-

M C

ompo

nent

Sco

re

75

70

65

60

55

50

45

40

35

30Baseline

27% reduction ofsymptoms p<0.001

N=21

Day 30

Following a 30 day administration of Sentra AMsymptoms of fatigue, anxiety and AM grogginess related to Posttraumatic Stress on the Military Checklist for PTSD the PCL-M.1

Improving Daytime Fatigue

ESS

Slee

p Sc

ore

12

10

8

6

4

2

0Baseline

p<0.001N=21

Day 30

Following a 30 day administration of Sentra AM, subjects suffering from symptoms related to

Epworth Sleepiness Scale.1

1

“Administration of an amino acid-based regimen for the management of autonomic Sentra AM®Fatigue & Cognitive Disorders

Page 3: Sentra AM: Safely Manage Fatigue and Cognitive Disorders

Sentra AM® Product Information 3

Improving Cognitive Function

Change in Mental Health Rating SF-36

PCL-

M C

ompo

nent

Sco

re

45

40

35

30

25

20

15

10

5

0Baseline

57% improvementover 30 days

p<0.001N=21

Day 30

Following a 30 day administration of Sentra AM, subjects suffering from symptoms related to Posttraumatic stress improved mental health scores an average of 57% as measured by the SF-36.1 A score of 50 is considered healthy and normal. Most subjects scored below 25 at baseline.

Patients with fatigue and CD may require additional amounts of choline, glutamine and carnitine to restore and maintain nervous system functions.Sustained nervous system dysfunction associated with fatigue and CD increases metabolic demand for certain nutrients,

When the usual rate of synthesis is no longer

nutrients become conditionally essential,

maintain homeostasis.

1Shell WE; Charuvastra M; Breitstein M; Pavlik S; Charuvastra A; May L; Silver D “Administration of an amino acid-based regimen for the management of autonomic nervous system dysfunction related to combat-induced illness” Journal of Central Nervous System Disease 2014:6

Sentra AM®Fatigue & Cognitive Disorders

Addressing the Increased Nutritional Requirements of Fatigue and Cognitive Disorders

Page 4: Sentra AM: Safely Manage Fatigue and Cognitive Disorders

Sentra AM® Product Information 4

The pharmacodynamic properties of Sentra AM are directly related to the effects of amino acid and other precursors on neurotransmitter activity which are responsible for the synthesis of the autonomic nervous system.The use of Sentra AM in management of fatigue and cognitive disorders is supported by experimental and clinical data which have

restoring the balance of nervous system activity.Sentra AM is formulated with Targeted Cellular Technology® (TCT) a patented integrated molecular system that delivers milligram quantities of amino acids and other ingredients to target cells in a time sensitive

promote neurotransmitter production.

Pharmacodynamics

No Reported Adverse Side Effects

Improve AM Grogginess, Mental Health and Fatigue

Restore Key Amino Acids, Nutrients and Neurotransmitters

No Potential for Addiction

No Drug-Half Life

No Attenuation

Flexible Dosing

Why is Sentra AM® a Good Choice?

Neurotransmitters

Neurotransmittersheld in storage

ReleaseBinding

SynapseReceptor site

Change inpotential

Neurotransmitters

Neurotransmittersheld in storage

ReleaseBinding

SynapseReceptor site

Change inpotential

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Neurotransmittersheld in storage

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ChChCChChChChChChChChChChChChChChChChChChChChChChChChChChChCChChChChChChChChChChChChChChChChhChhCChhChhChChhCCCCCChC anananananananananananannanaanananananannanananananannanaanananananananannaaaaannngegegegegegegegegegegegeeegegeegegegegegegeegegegeegegegegegeegegegegegegegegegegeggegeeegegeggegeee iiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiinnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnChhhChhChChChChChChChChChhChChChChChChChChCChChChhChhhhChhh nannnanananaanananananannananananananananananananaananananaa eegegegegeegegegeegegegegegegegeegegegegeggegegeeegegeege iiiiiiiiiiiiiiiiiiiiiiiiiiiiiinnnnnnnnnnnnnnnnnnnnnnnnnnnpopopopopopopopopopopopopopopopopopopopopopopopopopopopopopopopopopopopopopopopoppooppopopopopoppppppooopopppppp tetetetetetetetetetetettetetetetetetetetettetetetteteteteeteteteteetetteteetetetetteteeteteeteentntntntntntntntntntntntntntnttntntntntnttntntntntntnntntntntnnntntntntttntntntnttnntn iiaiaiaiaaaaaiaiaiaiaiaiaaiaaiaiaiaiaaiaiaiaiaaaaiaaallllllllllllllllpopoppppopopopopopopopopopopoopopopopopopoppopppopp tetetetetettetetetetetetetetetetettetetttetetetttetetetteteteeeentnntntntntntnttntntntntntntntntntntntnttttnttttnttntntntntnttiiiaiaiaiiiaiaiaiaiaiaiaiaiaiaiaiaaiaiaiaaiaiaiaaaaalllllllllllllll

gggggggggggggggggggggggggggggggggggggggggggggggggggggggChange inpotential

BiBiBiBiBiiiBiBiBiBiiBiBiBiiBiBiBiBiBiBiBiBiBBiiBiBiBiBBiBiBiBBiBiBBBiii dddddndndndndnddndndddndnddndndndddndndnddndndnddndndndndndndndndndnddndndndndndndndndndnddnddndddnddddnn ininininininiininnininninininininininininininniniininninnininininninninnnnnninnggggggggggggggggggggggggggggggggggggggggggggggggggBiiiBiBiiiBiBiiBiBiBBiBiBiBBiBiBiiiBiBiBiBiBiBBBiiBBBinnnndnndnddndndndndndndndndndndndndndndndndnddnndnndndndndndndndiniinininiinininiinininnininininnininninininininnnnnnnninggggggggggggggggggggggggggggggggggBBBBBiBiBiBiBiBiBBiBBBiBBBiBBBBBBiBiBiBBBBBBiBBBiBBBBiBiBBBBBiBiBiBiiBBBBii dddddddddddddddd ninnininnnininnininnininiininiiddddddddddddddddd niinnninininininniniinininnnnniBinding

Targeted Cellular Technology®Neurotransmitter PrecursorUptake StimulatorAdenosine AntagonistNeuron ActivatorAttenuation Inhibitor

Sentra AM is indicated for the dietary management of fatigue and cognitive disorders.

2-4 capsules once daily in the morning

Recommended Dosing:

Page 5: Sentra AM: Safely Manage Fatigue and Cognitive Disorders

Sentra AM® Product Information 5

Precautions and ContraindicationsSentra AM is contraindicated in an extremely small number of patients with hypersensitivity to any of the nutritional components of Sentra AM.

Adverse ReactionsIngestion of Choline at high doses of up to 15 grams daily is generally well tolerated. The most common adverse reactions of higher doses — from 15 to 30 grams daily — are nausea, abdominal cramps, and diarrhea. Sentra AM contains less than 1 gram per dose of amino acids however, some patients may experience these symptoms at lower doses. The total combined amount of amino acids in each Sentra AM capsule does not exceed 300 mg.

Drug InteractionsSentra AMexperience has shown that administration of Sentra AM may allow for lowering the dose of co-administered drugs under physician supervision.

OverdoseThere Sentra AM as the total amount of amino acids in a one month supply (60 capsules) is less than 30 grams. Overdose symptoms may include

Safety Information

For more information, visit www.TMedPharma.com