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Potent Anti-cancer plant Semecarpus anacardium L.
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Page 1: Semecarpus

Potent Anti-cancer plant

Semecarpus anacardium L.

Page 2: Semecarpus

Presented by

Dr. Sudhakar Kokate

Director PPRC, India

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PPRC/INDIA 01

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PPRC/INDIA 02

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PPRC/INDIA 03

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Normal cell Cancer cells

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Semecarpus anacardium L.

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Des

crip

tion

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Well-known in Ayurveda & Siddha

medicine

Popularly known as “Marking Nut tree”

Family: Anacardiaceae

Medium sized to large tree

Ht: 15-25 m, grey bark

PPRC/INDIA 08

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Leaves: simple, alternate, obovate

oblong, rounded at the apex

Flowers: greenish white

Fruits: ovoid / oblong drupes, 2.5 cm

long

Nut: 1” x 0.75” x 0.33” Avg. wt: 3.5 gm

PPRC/INDIA 09

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Che

mic

al c

onst

itu

ents

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PPRC/INDIA 11

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PPRC/INDIA 12

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PPRC/INDIA 13

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Bio

-act

ivit

y

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1. Anti-inflammatory

2. Anti-arthritic

3. Contraceptive agent

4. Hypoglycaemic

5. Lipoxygenase inhibitory

6. Hypo-lipidemic

PPRC/INDIA 16

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7. Hypo-cholesterolemic

8. Anti-microbial

9. Anti-stress

10.Spasmogenic effect

11.Immunomodulatory

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Ant

i-tu

mou

r-a

ctiv

ity

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A variety of “Marking Nut”

preparations used in clinical practice

Encouraging results reported for

oesophagus, liver, urinary bladder,

cancer and leukaemia

The flavonoids present in nut have the

ability to prevent various cancers

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It showed differential action in ascites

tumour in the rats

Extract revealed anti-carcinogenic

activity against AFB1 mediated

hepatocellular carcinoma

Nut milk extract also showed anti-

tumour activity

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Anti-peroxidative capacity of the nut

extract

Act as an anti-neoplastic agent

Regulating the key enzymes

Significant role in mitochondrial energy

production

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Dise

ase

cur

e

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1. Dyspepsia

2. Nervous debility

3. Acute rheumatism

4. Asthma

5. Cough

6. Swelling

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7. Piles

8. Helmintic infections

9. Gout

10.Vision improvement

11.Leucoderma

12.Syphilis

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13.Gonorrhoea

14.Wound healing

15.Diabetes

16.Urinary diseases

17.Leprosy

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Thank you!!