SEER Cancer Statistics Review 1975-2016 National Cancer Institute Joinpoint Regression Program Version 4.7, February 2019, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/). The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130). a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta). b Trends are from the SEER 21 areas (SEER 9 areas, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey, Georgia excluding ATL/RG, Idaho, New York and Massachusetts). c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention. d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint. e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. g Data for American Indian/Alaska Native are based on the Purchased/Referred Care Delivery Area (PRCDA) counties. * The APC/AAPC is significantly different from zero (p<.05). - Joinpoint regression line analysis could not be performed on data series. JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPC d Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16 SEER 9 Delay-Adjusted Incidence a , 1975-2016 All Races 1975-81 5.9* 1981-05 2.9* 2005-16 1.6* 1.6* 1.6* White 1975-81 6.2* 1981-05 3.2* 2005-16 1.9* 1.9* 1.9* Black 1975-16 -0.3 -0.3 -0.3 SEER 21 Delay-Adjusted Incidence b , 2000-2016 All Races 2000-05 3.5* 2005-16 1.3* 1.3* 1.3* White 2000-05 3.8* 2005-16 1.6* 1.6* 1.6* White NH ef 2000-05 4.3* 2005-16 1.9* 1.9* 1.9* Black 2000-16 0.0 0.0 0.0 Black NH ef 2000-16 0.1 0.1 0.1 API e 2000-16 -0.4 -0.4 -0.4 AI/AN eg 2000-16 2.7* 2.7* 2.7* Hispanic f 2000-16 0.7 0.7 0.7 U.S. Cancer Mortality c , 1975-2016 Note- Alternate mortality trends adjusted for ICD-9/ICD-10 coding change available at: https://surveillance.cancer.gov/joinpoint/table1.html. All Races 1975-77 4.7 1977-90 1.4* 1990-02 -0.3 2002-09 0.6 2009-14 -1.2* 2014-16 -8.4* -2.5* -4.9* White 1975-77 5.0 1977-90 1.5* 1990-02 -0.1 2002-09 0.8* 2009-14 -1.0 2014-16 -8.1* -2.2* -4.6* Black 1975-14 -0.8* 2014-16 -17.9 -4.9 -9.8 U.S. Cancer Mortality c , 2000-2016 All Races 2000-09 0.5* 2009-14 -1.2 2014-16 -8.5* -2.5* -4.9* White 2000-13 0.4* 2013-16 -6.5* -2.0* -4.8* White NH ef 2000-13 0.6* 2013-16 -6.3* -1.8* -4.6* Black 2000-14 -1.2* 2014-16 -16.1 -4.7 -9.0 Black NH ef 2000-14 -1.2* 2014-16 -16.1 -4.8 -9.0 API e 2000-16 -0.9 -0.9 -0.9 AI/AN eg 2000-16 -2.9 -2.9 -2.9 Hispanic f 2000-16 -0.8 -0.8 -0.8 Table 16.1 Melanoma of the Skin (Invasive) Trends in SEER Incidence ab and U.S. Mortality c Using the Joinpoint Regression Program, 1975-2016 With up to Five Joinpoints, 2000-2016 With up to Three Joinpoints, Both Sexes by Race/Ethnicity
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SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding
SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska
Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series
All Races 2000-09 05 2009-14 -12 2014-16 -85 -25 -49
White 2000-13 04 2013-16 -65 -20 -48
White NHef 2000-13 06 2013-16 -63 -18 -46
Black 2000-14 -12 2014-16 -161 -47 -90
Black NHef 2000-14 -12 2014-16 -161 -48 -90
APIe 2000-16 -09 -09 -09
AIANeg 2000-16 -29 -29 -29
Hispanicf 2000-16 -08 -08 -08
Table 161
Melanoma of the Skin (Invasive)
Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program
1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints
Both Sexes by RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding
SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska
Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series
All Races 2000-09 10 2009-14 -13 2014-16 -85 -25 -50
White 2000-09 11 2009-14 -10 2014-16 -83 -22 -47
White NHef 2000-09 13 2009-14 -09 2014-16 -81 -20 -46
Black 2000-16 -12 -12 -12
Black NHef 2000-16 -11 -11 -11
APIe 2000-16 -21 -21 -21
AIANeg 2000-16 -22 -22 -22
Hispanicf 2000-16 -05 -05 -05
Table 162
Melanoma of the Skin (Invasive)
Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program
1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints
Males by RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding
SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska
Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series
Note- Alternate mortality trends adjusted for ICD-9ICD-10 coding change available at httpssurveillancecancergovjoinpointtable1html
All Races 1975-88 08 1988-14 -06 2014-16 -93 -26 -51
White 1975-86 11 1986-13 -03 2013-16 -57 -21 -44
Black 1975-97 03 1997-16 -26 -26 -26
US Cancer Mortalityc 2000-2016
All Races 2000-14 -06 2014-16 -93 -26 -50
White 2000-13 -02 2013-16 -59 -22 -45
White NHef 2000-13 00 2013-16 -56 -19 -42
Black 2000-16 -27 -27 -27
Black NHef 2000-16 -28 -28 -28
APIe 2000-16 -01 -01 -01
AIANeg - - - -
Hispanicf 2000-16 -11 -11 -11
Table 163
Melanoma of the Skin (Invasive)
Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program
1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints
Females by RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Note Delay-adjusted melanoma of the skin rates cannot be calculated for the SEER 9 Black population due to low case countsReference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review
a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval
All Races Whites Total Males Females Total Males Females
Delay-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Age-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 005 225 029 Asian 0 000 000 000 018 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
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ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding
SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska
Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series
All Races 2000-09 10 2009-14 -13 2014-16 -85 -25 -50
White 2000-09 11 2009-14 -10 2014-16 -83 -22 -47
White NHef 2000-09 13 2009-14 -09 2014-16 -81 -20 -46
Black 2000-16 -12 -12 -12
Black NHef 2000-16 -11 -11 -11
APIe 2000-16 -21 -21 -21
AIANeg 2000-16 -22 -22 -22
Hispanicf 2000-16 -05 -05 -05
Table 162
Melanoma of the Skin (Invasive)
Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program
1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints
Males by RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding
SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska
Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series
Note- Alternate mortality trends adjusted for ICD-9ICD-10 coding change available at httpssurveillancecancergovjoinpointtable1html
All Races 1975-88 08 1988-14 -06 2014-16 -93 -26 -51
White 1975-86 11 1986-13 -03 2013-16 -57 -21 -44
Black 1975-97 03 1997-16 -26 -26 -26
US Cancer Mortalityc 2000-2016
All Races 2000-14 -06 2014-16 -93 -26 -50
White 2000-13 -02 2013-16 -59 -22 -45
White NHef 2000-13 00 2013-16 -56 -19 -42
Black 2000-16 -27 -27 -27
Black NHef 2000-16 -28 -28 -28
APIe 2000-16 -01 -01 -01
AIANeg - - - -
Hispanicf 2000-16 -11 -11 -11
Table 163
Melanoma of the Skin (Invasive)
Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program
1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints
Females by RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Note Delay-adjusted melanoma of the skin rates cannot be calculated for the SEER 9 Black population due to low case countsReference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review
a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval
All Races Whites Total Males Females Total Males Females
Delay-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Age-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 005 225 029 Asian 0 000 000 000 018 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Joinpoint Regression Program Version 47 February 2019 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding
SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska
Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series
Note- Alternate mortality trends adjusted for ICD-9ICD-10 coding change available at httpssurveillancecancergovjoinpointtable1html
All Races 1975-88 08 1988-14 -06 2014-16 -93 -26 -51
White 1975-86 11 1986-13 -03 2013-16 -57 -21 -44
Black 1975-97 03 1997-16 -26 -26 -26
US Cancer Mortalityc 2000-2016
All Races 2000-14 -06 2014-16 -93 -26 -50
White 2000-13 -02 2013-16 -59 -22 -45
White NHef 2000-13 00 2013-16 -56 -19 -42
Black 2000-16 -27 -27 -27
Black NHef 2000-16 -28 -28 -28
APIe 2000-16 -01 -01 -01
AIANeg - - - -
Hispanicf 2000-16 -11 -11 -11
Table 163
Melanoma of the Skin (Invasive)
Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program
1975-2016 With up to Five Joinpoints 2000-2016 With up to Three Joinpoints
Females by RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Note Delay-adjusted melanoma of the skin rates cannot be calculated for the SEER 9 Black population due to low case countsReference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review
a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval
All Races Whites Total Males Females Total Males Females
Delay-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Age-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 005 225 029 Asian 0 000 000 000 018 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Note Delay-adjusted melanoma of the skin rates cannot be calculated for the SEER 9 Black population due to low case countsReference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review
a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval
All Races Whites Total Males Females Total Males Females
Delay-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Age-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 005 225 029 Asian 0 000 000 000 018 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
Age-adjusted SEER Incidencea Rates by Year Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 005 225 029 Asian 0 000 000 000 018 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
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ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention
Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 005 225 029 Asian 0 000 000 000 018 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
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ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted
b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted
c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 005 225 029 Asian 0 000 000 000 018 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)
Based on follow-up of patients into 2016 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey
Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2016
d Period survival provides a 2015 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)
e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2009-2015 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 005 225 029 Asian 0 000 000 000 018 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males and Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 005 225 029 Asian 0 000 000 000 018 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Males
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 005 225 029 Asian 0 000 000 000 018 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables
SEERa Relative Survival (Percent)By Year of Diagnosis
All Races Females
Year of Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 005 225 029 Asian 0 000 000 000 018 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 005 225 029 Asian 0 000 000 000 018 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Both Sexes 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 003 277 039 Asian 0 000 000 000 019 006
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Males 2014-2016 By RaceEthnicity
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Devcan 677 April 2019 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta
San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US
a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties
b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry
- Statistic could not be calculatedA percent of 000 represents a value that is below 0005
Risk of Being Risk of Being
Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying
Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer
All Races 0 000 001 007 179 019 Asian 0 000 000 000 016 007
Risk of Being Diagnosed With Cancer in 10 20 and 30 Years
Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and
Lifetime Risk of Dying from Cancer Given Alive at Current Age
Females 2014-2016 By RaceEthnicity
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 47 February 2019 National Cancer Institute
- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts
c The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2016
d The 2007-2016 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2016
e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry
f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties
g US Mortality Files National Center for Health Statistics CDCh The 2007-2016 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2016 The APC is significantly different from zero (plt05)
SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa
By RaceEthnicity and Sex
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta
The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)
b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts
- Statistic not shown Rate based on less than 16 cases for the time interval
All Races Whites Blacks Total Males Females Total Males Females Total Males Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 249 001
High Five StatesIdaho 338 020 01(0116) 3594c
Utah 328 017 02(0117) 3192c
West Virginia 318 017 03(0124) 2768c
Kentucky 308 011 04(0118) 2377c
Kansas 300 014 05(0128) 2049c
Low Five StatesTexas 208 004 47(4249) -1651c
Louisiana 203 009 48(4050) -1847c
New York 199 004 49(4450) -2017c
Hawaii 162 014 50(4750) -3489c
DC 082 017 51(5151) -6697c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males and Females
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Males
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)
b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval
State Rate SE Rank(CI)d PD TOTAL US 155 001
High Five StatesIdaho 229 023 01(0127) 4774c
Delaware 202 027 02(0144) 3043c
West Virginia 196 018 03(0138) 2695c
Maine 195 021 04(0143) 2582c
Colorado 194 012 05(0128) 2563c
Low Five StatesNew York 129 005 46(3749) -1691c
Maryland 129 009 47(3050) -1695c
Texas 124 004 48(4050) -1996c
North Dakota 105 023 49(1450) -3186c
Hawaii 092 014 50(4050) -4037c
State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD
Age-Adjusted Cancer Deatha Rates By State All Races 2012-2016
Females
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
a US 2016 cancer prevalence counts are based on 2016 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112016 US population estimates based on the average of 2015 and 2016 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 24 years
b Maximum limited-duration prevalence is 24 years for 1992-2016 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 24 years ago were estimated using the completeness index method (Capocaccia et al 1997
Merrill et al 2000)e Complete prevalence is obtained by summing 0 to lt24 and gt=24- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available
Years Since Diagnosis 0 to lt5 5 to lt10 10 to lt15 15 to lt20 20 to lt24 0 to lt24b gt=24d Completee
Race Sex All Races Both Sexes 340956 252815 188823 141530 79525 1003650 191958 1195608
Estimated United States Cancer Prevalence Countsa on January 1 2016By RaceEthnicity Sex and Years Since Diagnosis
Estimated prevalence percenta on January 1 2016 of the SEER population diagnosed in the previous 24 yearsBy Age at Prevalence RaceEthnicity and Sex
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
0
5
10
15
20
25
30
35
40
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
40
1975 1985 1995 2005 2016
Delay-Adjusted IncidenceDelay-Adjusted Incidence
Observed IncidenceObserved Incidence
MortalityMortality
SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesMelanoma of the Skin White by Sex
a
Figure 161
Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
Joinpoint Analyses for Whites and Blacks from 1975-2016and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2016
0
5
10
15
20
25
30
35
1975 1985 1995 2005 20160
5
10
15
20
25
30
35
1975 1985 1995 2005 2016
White
Black
API
AIAN
Hispanic
SEER Incidence and US Death RatesMelanoma of the Skin Both Sexes
Figure 162
Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 47 February 2019 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2016 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2016 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry
Incidence MortalityRate per 100000 Rate per 100000
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Melanoma of the SkinSEER Incidence 2004-2006 vs 2014-2016
White by Age and Sex
Source SEER 13 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey Los Angeles Alaska Native Registry and Rural Georgia) Rates are age-adjusted as appropriate to the 2000 US Std Population (19 age groups - Census P25-1103)
Rate per 100000
Age at Diagnosis
SEE
R C
ancer Statistics Review
1975-2016N
ational Cancer Institute
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity
Graph - SEER Incidence by Age and Sex
Graph - 5-Year SEER Conditional Relative Survival
Figure 164
Melanoma of the Skin5-Year SEER Conditional Relative Survival and
95 Confidence Intervals
Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error
0
20
40
60
80
100Percent Surviving Next 5 Years
Stage at Diagnosis
Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years
2000-2015 by stage at diagnosis
Survival Time Since Diagnosis
Localized Regional Distant Unstaged
0 year (at diagnosis) 1 year 3 years
SEER Cancer Statistics Review 1975-2016 National Cancer Institute
Trends in SEER Incidence and US Mortality Both Sexes
Trends in SEER Incidence and US Mortality Males
Trends in SEER Incidence and US Mortality Females
Annual Delay-adjusted Incidence Rates
Annual Incidence Rates
Annual Death Rates
Incidence and Mortality Rates by Age
5-year Relative and Period Survival
Relative Survival by Year of Diagnosis Both Sexes
Relative Survival by Year of Diagnosis Males
Relative Survival by Year of Diagnosis Females
Risk of DevelopingDying Both Sexes
Risk of DevelopingDying Males
Risk of DevelopingDying Females
Rates and Trends by RaceEthnicity
Age-Adjusted SEER Incidence Rates by Registry
Age-Adjusted SEER Death Rates by Registry
Age-Adjusted Cancer Death Rates By State Both Sexes
Age-Adjusted Cancer Death Rates By State Males
Age-Adjusted Cancer Death Rates By State Females
US Prevalence Estimates
Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Sex
Graph - SEER Incidence and US Death Rates by RaceEthnicity