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Seborrhoea and otitis in a springer spaniel Author: Ewan Ferguson Editor: David Lloyd © European Society of Veterinary Dermatol
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Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

Mar 28, 2015

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Page 1: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

Seborrhoea and otitisin a springer spaniel

Author: Ewan FergusonAuthor: Ewan Ferguson Editor: David LloydEditor: David Lloyd

© European Society of Veterinary Dermatology © European Society of Veterinary Dermatology

Page 2: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

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• Entire 8-year-old male Welsh springer spaniel

• Weight 36 kg

• Non-seasonal dermatosis of 2 years duration

• Moderate erythema and severe lichenification of pinnae, periaural skin, ventral neck, tail and abdomen. Moderate hyperpigmentation present

History and presentingclinical signs - 1

• Entire 8-year-old male Welsh springer spaniel

• Weight 36 kg

• Non-seasonal dermatosis of 2 years duration

• Moderate erythema and severe lichenification of pinnae, periaural skin, ventral neck, tail and abdomen. Moderate hyperpigmentation present

HistoryHistory

Page 3: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

• Generalised seborrhoea, strong odour and dull brittle coat. Purulent discharge from ears. Affected areas severely pruritic

• Thirst and appetite unchanged. Alert but less active than littermate

• Minimal response to appropriate doses of systemic antibiotics and glucocorticoids

History and presentingclinical signs - 2

• Generalised seborrhoea, strong odour and dull brittle coat. Purulent discharge from ears. Affected areas severely pruritic

• Thirst and appetite unchanged. Alert but less active than littermate

• Minimal response to appropriate doses of systemic antibiotics and glucocorticoids

HistoryHistory

Page 4: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

Clinical findings on first presentation - 1

SignsSigns

Page 5: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

Clinical findings on first presentation - 2

SignsSigns

Page 6: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

How would youapproach this case?

• What are the next steps you would take?

• Make a list of your principle differential diagnoses

• List any samples you would collect

• List any tests you would perform to assist in making a definitive diagnosis

• What are the next steps you would take?

• Make a list of your principle differential diagnoses

• List any samples you would collect

• List any tests you would perform to assist in making a definitive diagnosis

ApproachApproach

Page 7: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

• Next steps• A thorough physical examination is mandatory• Comparison with littermate would be valuable

• Principle differential diagnoses• Primary problems: hypothyroidism, demodicosis,

ectoparasitism, food intolerance, atopy• Secondary problems: Malassezia dermatitis,

pyoderma, bacterial otitis

Caseinvestigation - 1

• Next steps• A thorough physical examination is mandatory• Comparison with littermate would be valuable

• Principle differential diagnoses• Primary problems: hypothyroidism, demodicosis,

ectoparasitism, food intolerance, atopy• Secondary problems: Malassezia dermatitis,

pyoderma, bacterial otitis

ApproachApproach

Page 8: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

Caseinvestigation - 2

• Samples• Deep and superficial skin scrapings, tape strippings

and impression smears for cytology, biochemistry and haematology panels, swabs from ears for bacteriology

• Tests• TSH response test, elimination diet

• Samples• Deep and superficial skin scrapings, tape strippings

and impression smears for cytology, biochemistry and haematology panels, swabs from ears for bacteriology

• Tests• TSH response test, elimination diet

ApproachApproach

Page 9: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

Test results - 1

• Comparison with littermate• Obese, less active

• Skin scrapings

• No ectoparasites or fungal elements

• Tape strippings• Many Malassezia yeasts in all samples

• Aural swabs• Smears show yeasts and Gram-negative rods• Pseudomonas spp. on culture

• Comparison with littermate• Obese, less active

• Skin scrapings

• No ectoparasites or fungal elements

• Tape strippings• Many Malassezia yeasts in all samples

• Aural swabs• Smears show yeasts and Gram-negative rods• Pseudomonas spp. on culture

TestsTests

Page 10: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

Clinical appearance -comparison with littermate

TestsTests

Page 11: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

Test results - 2

• Blood tests• Mild normochromic, normocytic anaemia• Fasted serum cholesterol = 8.2 mmol/l

• Elimination diet• No change in clinical signs

• TSH response test (total plasma T4)• Basal = 24.5 nmol/l• 6 hrs post TSH = 29.3 nmol/l

• Blood tests• Mild normochromic, normocytic anaemia• Fasted serum cholesterol = 8.2 mmol/l

• Elimination diet• No change in clinical signs

• TSH response test (total plasma T4)• Basal = 24.5 nmol/l• 6 hrs post TSH = 29.3 nmol/l

TestsTests

Page 12: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

What is yourdiagnosis?

• What is your principle diagnosis?

• List any additional problems which you think may need treatment

• Are there any other possibilities which should be considered at this stage?

• What is your principle diagnosis?

• List any additional problems which you think may need treatment

• Are there any other possibilities which should be considered at this stage?

TestsTests

Page 13: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

Diagnosis

• Hypothyroidism with secondary Malassezia dermatitis and otitis with Pseudomonas sp. infection

• It would probably be difficult to accurately assess any concurrent disease until these problems have been controlled

• Hypothyroidism with secondary Malassezia dermatitis and otitis with Pseudomonas sp. infection

• It would probably be difficult to accurately assess any concurrent disease until these problems have been controlled

TestsTests

Page 14: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

How would you deal with this case?

List the steps you would now take to treat:

• The hypothyroidism

• The Malassezia dermatitis

• The Pseudomonas otitis

TreatmentTreatment

List the steps you would now take to treat:

• The hypothyroidism

• The Malassezia dermatitis

• The Pseudomonas otitis

Page 15: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

Treatment - 1

• Hypothyroidism• Oral levothyroxine given at 10-20 µg/kg bid

• Monitor 4 hour post-pill serum total T4 concentrations after 12 weeks

• Hypothyroidism• Oral levothyroxine given at 10-20 µg/kg bid

• Monitor 4 hour post-pill serum total T4 concentrations after 12 weeks

TreatmentTreatment

Page 16: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

Treatment - 2

• Malassezia dermatitis• Whole body baths with 1% w/v selenium sulphide

shampoo followed by 2 mg/ml enilconazole rinse. Treatment repeated every 4 days

• If response was poor, systemic ketoconazole at 10 mg/kg bid might be considered. Not first choice of therapy in this case, in view of concurrent endocrinopathy.

• Malassezia dermatitis• Whole body baths with 1% w/v selenium sulphide

shampoo followed by 2 mg/ml enilconazole rinse. Treatment repeated every 4 days

• If response was poor, systemic ketoconazole at 10 mg/kg bid might be considered. Not first choice of therapy in this case, in view of concurrent endocrinopathy.

TreatmentTreatment

Page 17: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

Treatment - 3

• Pseudomonas otitis• Flush canals under general anaesthetic to remove

debris and inspect tympanic membranes• Bulla radiographs if otitis media suspected• In this case, 0.02% chlorhexidine washes followed

by Tris-EDTA drops and 0.3% gentamicin drops were used

• Pseudomonas otitis• Flush canals under general anaesthetic to remove

debris and inspect tympanic membranes• Bulla radiographs if otitis media suspected• In this case, 0.02% chlorhexidine washes followed

by Tris-EDTA drops and 0.3% gentamicin drops were used

TreatmentTreatment

Page 18: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

Response to treatment

• Treated with 400 µg/kg bid. Washes applied once weekly

• Weight reduced from 36 kg to 31 kg after 6 months. Post-pill TT4 32 nmol/l

• Good hair regrowth in all affected areas. Some seborrhoea still present. Odour, lichenification, erythema and hyperpigmentation greatly reduced

• Minimal pruritus. Otitis now resolved

NotesNotes

• Treated with 400 µg/kg bid. Washes applied once weekly

• Weight reduced from 36 kg to 31 kg after 6 months. Post-pill TT4 32 nmol/l

• Good hair regrowth in all affected areas. Some seborrhoea still present. Odour, lichenification, erythema and hyperpigmentation greatly reduced

• Minimal pruritus. Otitis now resolved

Page 19: Seborrhoea and otitis in a springer spaniel Author: Ewan FergusonEditor: David Lloyd © European Society of Veterinary Dermatology.

CLOSECLOSE History | Signs | Approach | Tests | Treatment | NotesHistory | Signs | Approach | Tests | Treatment | Notes

Review

• If you would like to review this case, please use the navigation buttons below

• Press “CLOSE” to close this case and return to the main menu

• If you would like to review this case, please use the navigation buttons below

• Press “CLOSE” to close this case and return to the main menu

NotesNotes