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Seborrheic Keratosis
definition
Benign eccrine poromas that present as multiple oval, brown-to-black plaques, located mostly on the chest and back. The age of onset is usually in the fourth or fifth decade.
Bowenoid papulosis is a rare sexually transmitted disorder thought to be caused by human papillomavirus type 16. This disorder is characterized by lesions that are found on the genitals of males and females. The lesions are reddish brown or violet in colour, small, solid, raised and sometimes velvety. (NORD/G. Eysenbach)
A persistent progressive non-elevated red scaly or crusted plaque which is due to an intradermal carcinoma and is potentially malignant. Atypical squamous cells proliferate through the whole thickness of the epidermis. The lesions may occur anywhere on the skin surface or on mucosal surfaces. The cause most frequently found is trivalent arsenic compounds. Freezing, cauterization or diathermy coagulation is often effective. (From Rook et al., Textbook of Dermatology, 4th ed, pp2428-9)
Circumscribed lesion that occurs mainly on the face and scalp and consists predominantly of sebaceous glands, abortive hair follicles and ectopic apocrine glands. It is generally present at birth or in early childhood, but at times it may arise in adult life. The slightly raised yellow, orange or light-brown plaques present a smooth or velvety surface. With puberty, they become raised, thickened, and nodular. Secondary neoplastic changes occur in 10 to 30 per cent of lesions, the most common neoplasms being basal cell carcinoma and syringocystadenoma papilliferum.
synonyms
Nevus Sebaceous of Jadassohn, Sebaceous Nevus
UMLS
Linear sebaceous nevus sequence, Nevus sebaceous of Jadassohn
Nevocellular nevus presenting as a pigmented area with increased hair growth. It is present at birth but may continue to develop during infancy. Usually, the light brown to black coloured lesions are raised, and deeper nodules may occur. The lesions vary in size from approximately 1 cm in diameter to large expanses, occasionally covering an entire trunk or leg (so-called giant or garment nevi).. Associated abnormalities such as meningeal involvement, spina bifida and club-foot may occur when the nevus is situated over the vertebral column or a limb.
A chronic, atrophic lymphocyte-mediated inflammatory dermatosis characterized by shiny, white atrophic patches with a predilection for the genital and perineal skin. The lesions corresponds to white, angular, flat, well-defined, indurated papules with an erythematous halo and follicular, black, keratotic plugs. The disorder is commoner in females than in males, and it peaks at two age groups: prepubertal and peri- or postmenopausal.
synonyms
Lichen Sclerosus et Atrophicus, White Spot Disease, Csillag's Disease
UMLS
Disease, white, spot, Lichen Sclerosus, Lichen Sclerosus et Atrophicus, Lichen sclerosus et atrophicus, NOS, Lichen, sclerosus, Lichen, sclerosus et atrophicus, White spot disease
A rare autosomal recessive disease characterized by photosensitivity, photodamage, cutaneous malignancies, severe ophthalmological abnormalities and often early death from malignancy.This light-provoked disease can affect all races. It is manifested as an extreme photosensitivity to ultraviolet light as the result of a deficiency in the enzyme that permits excisional repair of ultraviolet-damaged DNA. The skin of the patients is normal at birth and the changes occur almost exclusively in chronically sun-exposed areas of the body as a result of UV-light injury. The earliest lesions are usually irregular freckling and marked dryness of the sun-exposed areas. The face and hands are affected first, the neck, lips and conjunctivae becoming involved in time. Characteristic findings include mottled skin with erythema, telangiectases, solar elastosis and areas of atrophy as well as the development of numerous premalignancies and malignant tumours. Rigorous protection from sunlight beginning in early infancy has been show to slow the progression of serious cutaneous and ocular abnormalities.
Irradiation of the skin with 12 - 15 Gray or repeated irradiation with a smaller dose result in chronic radiodermatitis after two years or more. The skin is atrophic and shows telangiectasia due to dilation of a reduced skin vasculature. Pigmentation usually is reduced, but there may be small areas of increased pigment production and retention. Radionecrotic ulceration may occur, especially in moist areas.