Schistosoma Parasites • Scistosomes are NOT hermaphrodite (sexes are separate). • Male is flat and female is cylindrical. • Eggs are NOT operculated but have a spine. • Inside the snail: NO redia stage. • Infective stage: Cercaria NOT encysted metacercaria. • Mode of infection: skin penetration NOT by ingestion. Introduction Fasciola Paragonimus Heterophyes S.mansoni S.haematobium miracidium sporocyst redia Inside snail operculum spine Flat ♂ Cylindrical ♀ Cercaria
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Schistosoma Parasites
• Scistosomes are NOT hermaphrodite
(sexes are separate).
• Male is flat and female is cylindrical.
• Eggs are NOT operculated but have a spine.
• Inside the snail: NO redia stage.• Infective stage: Cercaria NOT encysted metacercaria.• Mode of infection: skin penetration NOT by ingestion.
Detection of anti-Schistosoma antibodies or antigen in patient’s serum
2- ELISA (Enzyme-linked immunosorbent assay)
3- IFAT (Indirect Fluorescent Antibody test)
wash wash
wash wash washAb
detected
wash wash wash Ag detected
Coating with Schisto Ag
Coating with anti-Schisto
monoclonal Ab
Latex particlesSensitized sheep RBCs
+ve
-ve
Schisto Ag Patient serum
Ab detected
Calcified bladder with hydroureter
Intestinal affection
Stenosed ureters and
hydronephrosis
II- Radiological imaging
S.haematobium infection S.mansoni infection
III- Endoscopyالمناظير
Cystoscopy S.haematobium
Colonoscopy, sigmoidoscopy S.mansoni
Done in chronic cases to detect lesions and take biopsies
Treatment
Praziquantel
Prevention and Control
- Mass treatment.
- Health Education.
- Snail control:
Physical methods
Biological methods
Chemical methods
X
Balanites aegyptica
Copper sulphate
Cercarial Dermatitis (Bather’s itch(
A condition that occurs due to penetration of cercariae of non-human species of schistosomes the skin of man.
Cercariae cannot go beyond the germinal layer.
Clinical picture:
Dermatitis, itching, oedema and secondary bacterial infection.
Treatment:
Antipruritics, antihistamincs,
antibiotics.
M.C.Q.
The major cause of morbidity in schistosomiasis is: a- Migration of adult worms against blood stream. b- Migration of adult worms in the liver. c- Embolic lesions. d- Deposition of eggs in tissues.
Kato technique is used to diagnose: a- Paragonimiasis c- Schistosomiasis haematobium