SAFETY DATA SHEET - Thermo Fisher · 2016. 11. 4. · GeneChip® Hybridization, Wash and Stain Kit Not available. SAFETY DATA SHEET GHS product identifier Other means of identification

GeneChip® Hybridization, Wash and Stain Kit

Not available.

SAFETY DATA SHEET

GHS product identifier

Other means of identification

Section 1. Identification:

:


3420 Central Expressway, Santa Clara CA 95051 3420 Central Expressway, Santa Clara CA 95051

Supplier/Manufacturer

In case of emergency :

:

Chemtrec: 1 800 424 9300Outside USA & Canada: +1 703 527 3887

900720Code :

Section 2. Hazards identificationOSHA/HCS status : Pre-Hybridization Mix While this material is not considered hazardous by the

OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product.

2X Hybridization Buffer This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200).

DMSO This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200).

Nuclease-Free Water While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product.

Stain Cocktail 1 While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product.

Stain Cocktail 2 While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product.

Array Holding Buffer While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product.

Wash Buffer A While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product.

Wash Buffer B While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical

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Section 2. Hazards identification

Pre-Hybridization Mix Not classified.2X Hybridization Buffer SERIOUS EYE DAMAGE/ EYE IRRITATION - Category

2ADMSO FLAMMABLE LIQUIDS - Category 4

SERIOUS EYE DAMAGE/ EYE IRRITATION - Category 2B

Nuclease-Free Water Not classified.Stain Cocktail 1 Not classified.Stain Cocktail 2 Not classified.Array Holding Buffer Not classified.Wash Buffer A Not classified.Wash Buffer B Not classified.

Classification of the substance or mixture

:

Signal word : Pre-Hybridization Mix No signal word.2X Hybridization Buffer WarningDMSO WarningNuclease-Free Water No signal word.Stain Cocktail 1 No signal word.Stain Cocktail 2 No signal word.Array Holding Buffer No signal word.Wash Buffer A No signal word.Wash Buffer B No signal word.

Hazard statements : Pre-Hybridization Mix No known significant effects or critical hazards.2X Hybridization Buffer Causes eye irritation.DMSO Combustible liquid.

Causes eye irritation.Nuclease-Free Water No known significant effects or critical hazards.Stain Cocktail 1 No known significant effects or critical hazards.Stain Cocktail 2 No known significant effects or critical hazards.Array Holding Buffer No known significant effects or critical hazards.Wash Buffer A No known significant effects or critical hazards.Wash Buffer B No known significant effects or critical hazards.

Hazard pictograms :

Precautionary statements

GHS label elements

General : Pre-Hybridization Mix Not applicable.2X Hybridization Buffer Not applicable.DMSO Not applicable.Nuclease-Free Water Not applicable.Stain Cocktail 1 Not applicable.Stain Cocktail 2 Not applicable.Array Holding Buffer Not applicable.Wash Buffer A Not applicable.Wash Buffer B Not applicable.

to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product.

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Section 2. Hazards identificationPrevention : Pre-Hybridization Mix Not applicable.

2X Hybridization Buffer Wear eye or face protection. Wash hands thoroughly after handling.

DMSO Wear protective gloves. Wear eye or face protection.Keep away from flames and hot surfaces. - No smoking.Wash hands thoroughly after handling.

Nuclease-Free Water Not applicable.Stain Cocktail 1 Not applicable.Stain Cocktail 2 Not applicable.Array Holding Buffer Not applicable.Wash Buffer A Not applicable.Wash Buffer B Not applicable.

Response : Pre-Hybridization Mix Not applicable.2X Hybridization Buffer IF IN EYES: Rinse cautiously with water for several

minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical attention.

DMSO IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical attention.

Nuclease-Free Water Not applicable.Stain Cocktail 1 Not applicable.Stain Cocktail 2 Not applicable.Array Holding Buffer Not applicable.Wash Buffer A Not applicable.Wash Buffer B Not applicable.

Storage : Pre-Hybridization Mix Not applicable.2X Hybridization Buffer Not applicable.DMSO Store in a well-ventilated place. Keep cool.Nuclease-Free Water Not applicable.Stain Cocktail 1 Not applicable.Stain Cocktail 2 Not applicable.Array Holding Buffer Not applicable.Wash Buffer A Not applicable.Wash Buffer B Not applicable.

Disposal : Pre-Hybridization Mix Not applicable.2X Hybridization Buffer Not applicable.DMSO Dispose of contents and container in accordance with

all local, regional, national and international regulations.Nuclease-Free Water Not applicable.Stain Cocktail 1 Not applicable.Stain Cocktail 2 Not applicable.Array Holding Buffer Not applicable.Wash Buffer A Not applicable.Wash Buffer B Not applicable.

Supplemental label elements

: Pre-Hybridization Mix None known.2X Hybridization Buffer None known.DMSO None known.Nuclease-Free Water None known.Stain Cocktail 1 None known.Stain Cocktail 2 None known.Array Holding Buffer None known.Wash Buffer A None known.Wash Buffer B None known.

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Section 2. Hazards identificationHazards not otherwise classified

: Pre-Hybridization Mix None known.2X Hybridization Buffer None known.DMSO None known.Nuclease-Free Water None known.Stain Cocktail 1 None known.Stain Cocktail 2 None known.Array Holding Buffer None known.Wash Buffer A None known.Wash Buffer B None known.

Section 3. Composition/information on ingredients

Pre-Hybridization Mixsodium chloride 1 - 10 7647-14-5

2X Hybridization Buffersodium chloride 10 - 25 7647-14-5

DMSOdimethyl sulfoxide 100 67-68-5

Nuclease-Free Waterwater 100 7732-18-5

Stain Cocktail 1sodium chloride 1 - 10 7647-14-5

Stain Cocktail 2sodium chloride 1 - 10 7647-14-5

Array Holding Buffersodium chloride 1 - 10 7647-14-5

Wash Buffer Asodium chloride 1 - 10 7647-14-5

Ingredient name CAS number%

There are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section.

Substance/mixture :

Occupational exposure limits, if available, are listed in Section 8.

Mixture

Any concentration shown as a range is to protect confidentiality or is due to batch variation.

CAUTION : This product contains Sodium Azide. Build-ups of Sodium Azide may react with lead and copper plumbing to form highly explosive metal azides.CAUTION : This product contains Sodium Azide. Build-ups of Sodium Azide may react with lead and copper plumbing to form highly explosive metal azides.

Pre-Hybridization Mix Immediately flush eyes with plenty of water,occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs.

2X Hybridization Buffer Immediately flush eyes with plenty of water,occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Continue to rinse

Section 4. First aid measures

Eye contact :

Description of necessary first aid measures

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Section 4. First aid measuresfor at least 10 minutes. If irritation persists, get medical attention.

DMSO Immediately flush eyes with plenty of water,occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Continue to rinse for at least 10 minutes. If irritation persists, get medical attention.

Nuclease-Free Water Immediately flush eyes with plenty of water,occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs.

Stain Cocktail 1 Immediately flush eyes with plenty of water,occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs.

Stain Cocktail 2 Immediately flush eyes with plenty of water,occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs.

Array Holding Buffer Immediately flush eyes with plenty of water,occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs.

Wash Buffer A Immediately flush eyes with plenty of water,occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs.

Wash Buffer B Immediately flush eyes with plenty of water,occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs.

Pre-Hybridization Mix Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical attention if symptoms occur. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours.

2X Hybridization Buffer Remove victim to fresh air and keep at rest in a position comfortable for breathing. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. Get medical attention if adverse health effects persist or are severe. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway.Loosen tight clothing such as a collar, tie, belt or waistband. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours.

DMSO Remove victim to fresh air and keep at rest in a position comfortable for breathing. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. Get medical attention if adverse health effects persist or are severe. If unconscious, place in recovery position and get medical

Inhalation :

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Pre-Hybridization Mix Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur.

2X Hybridization Buffer Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Clean shoes thoroughly before reuse.

DMSO Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Clean shoes thoroughly before reuse.

Nuclease-Free Water Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur.

Stain Cocktail 1 Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur.

Stain Cocktail 2 Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur.

Array Holding Buffer Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur.

Wash Buffer A Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur.

attention immediately. Maintain an open airway.Loosen tight clothing such as a collar, tie, belt or waistband.

Nuclease-Free Water Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical attention if symptoms occur.

Stain Cocktail 1 Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical attention if symptoms occur. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours.

Stain Cocktail 2 Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical attention if symptoms occur. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours.

Array Holding Buffer Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical attention if symptoms occur. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours.

Wash Buffer A Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical attention if symptoms occur.

Wash Buffer B Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical attention if symptoms occur. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours.

Skin contact :

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Pre-Hybridization Mix Wash out mouth with water. Remove victim to fresh air and keep at rest in a position comfortable for breathing.If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Do not induce vomiting unless directed to do so by medical personnel. Get medical attention if symptoms occur.

2X Hybridization Buffer Wash out mouth with water. Remove dentures if any.Remove victim to fresh air and keep at rest in a position comfortable for breathing. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Get medical attention if adverse health effects persist or are severe.Never give anything by mouth to an unconscious person.If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway.Loosen tight clothing such as a collar, tie, belt or waistband.

DMSO Wash out mouth with water. Remove dentures if any.Remove victim to fresh air and keep at rest in a position comfortable for breathing. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Get medical attention if adverse health effects persist or are severe.Never give anything by mouth to an unconscious person.If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway.Loosen tight clothing such as a collar, tie, belt or waistband.

Nuclease-Free Water Wash out mouth with water. Remove victim to fresh air and keep at rest in a position comfortable for breathing.If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Do not induce vomiting unless directed to do so by medical personnel. Get medical attention if symptoms occur.

Stain Cocktail 1 Wash out mouth with water. Remove victim to fresh air and keep at rest in a position comfortable for breathing.If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Do not induce vomiting unless directed to do so by medical personnel. Get medical attention if symptoms occur.

Stain Cocktail 2 Wash out mouth with water. Remove victim to fresh air and keep at rest in a position comfortable for breathing.If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Do not induce vomiting unless directed to do so by medical personnel. Get medical attention if symptoms occur.

Array Holding Buffer Wash out mouth with water. Remove victim to fresh air and keep at rest in a position comfortable for breathing.

Wash Buffer B Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur.

Ingestion :

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Section 4. First aid measuresIf material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Do not induce vomiting unless directed to do so by medical personnel. Get medical attention if symptoms occur.

Wash Buffer A Wash out mouth with water. Remove victim to fresh air and keep at rest in a position comfortable for breathing.If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Do not induce vomiting unless directed to do so by medical personnel. Get medical attention if symptoms occur.

Wash Buffer B Wash out mouth with water. Remove victim to fresh air and keep at rest in a position comfortable for breathing.If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Do not induce vomiting unless directed to do so by medical personnel. Get medical attention if symptoms occur.

Most important symptoms/effects, acute and delayed

Inhalation : Pre-Hybridization Mix Exposure to decomposition products may cause a health hazard. Serious effects may be delayed following exposure.

2X Hybridization Buffer Exposure to decomposition products may cause a health hazard. Serious effects may be delayed following exposure.

DMSO No known significant effects or critical hazards.Nuclease-Free Water No known significant effects or critical hazards.Stain Cocktail 1 Exposure to decomposition products may cause a

health hazard. Serious effects may be delayed following exposure.

Stain Cocktail 2 Exposure to decomposition products may cause a health hazard. Serious effects may be delayed following exposure.

Array Holding Buffer Exposure to decomposition products may cause a health hazard. Serious effects may be delayed following exposure.

Wash Buffer A No known significant effects or critical hazards.Wash Buffer B Exposure to decomposition products may cause a

health hazard. Serious effects may be delayed following exposure.

Skin contact : Pre-Hybridization Mix No known significant effects or critical hazards.2X Hybridization Buffer No known significant effects or critical hazards.DMSO No known significant effects or critical hazards.Nuclease-Free Water No known significant effects or critical hazards.Stain Cocktail 1 No known significant effects or critical hazards.Stain Cocktail 2 No known significant effects or critical hazards.Array Holding Buffer No known significant effects or critical hazards.Wash Buffer A No known significant effects or critical hazards.

Pre-Hybridization Mix No known significant effects or critical hazards.2X Hybridization Buffer Causes eye irritation.DMSO Causes eye irritation.Nuclease-Free Water No known significant effects or critical hazards.Stain Cocktail 1 No known significant effects or critical hazards.Stain Cocktail 2 No known significant effects or critical hazards.Array Holding Buffer No known significant effects or critical hazards.Wash Buffer A No known significant effects or critical hazards.Wash Buffer B No known significant effects or critical hazards.

:Eye contact

Potential acute health effects

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Pre-Hybridization Mix No known significant effects or critical hazards.2X Hybridization Buffer May be irritating to mouth, throat and stomach.DMSO May be irritating to mouth, throat and stomach.Nuclease-Free Water No known significant effects or critical hazards.Stain Cocktail 1 No known significant effects or critical hazards.Stain Cocktail 2 No known significant effects or critical hazards.Array Holding Buffer No known significant effects or critical hazards.Wash Buffer A No known significant effects or critical hazards.Wash Buffer B No known significant effects or critical hazards.

:Ingestion

Wash Buffer B No known significant effects or critical hazards.

Over-exposure signs/symptoms

Skin contact

Ingestion

Inhalation Pre-Hybridization Mix No specific data.2X Hybridization Buffer No specific data.DMSO No specific data.Nuclease-Free Water No specific data.Stain Cocktail 1 No specific data.Stain Cocktail 2 No specific data.Array Holding Buffer No specific data.Wash Buffer A No specific data.Wash Buffer B No specific data.

Pre-Hybridization Mix No specific data.2X Hybridization Buffer No specific data.DMSO No specific data.Nuclease-Free Water No specific data.Stain Cocktail 1 No specific data.Stain Cocktail 2 No specific data.Array Holding Buffer No specific data.Wash Buffer A No specific data.Wash Buffer B No specific data.

Pre-Hybridization Mix No specific data.2X Hybridization Buffer No specific data.DMSO No specific data.Nuclease-Free Water No specific data.Stain Cocktail 1 No specific data.Stain Cocktail 2 No specific data.Array Holding Buffer No specific data.Wash Buffer A No specific data.Wash Buffer B No specific data.

:

:

:

Eye contact : Pre-Hybridization Mix No specific data.2X Hybridization Buffer Adverse symptoms may include the following:

irritationwateringredness

DMSO Adverse symptoms may include the following:irritationwateringredness

Nuclease-Free Water No specific data.Stain Cocktail 1 No specific data.Stain Cocktail 2 No specific data.Array Holding Buffer No specific data.Wash Buffer A No specific data.Wash Buffer B No specific data.

Indication of immediate medical attention and special treatment needed, if necessary

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Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.

Notes to physician : Treat symptomatically. Contact poison treatment specialist immediately if large quantities have been ingested or inhaled.

Specific treatments : No specific treatment.

See toxicological information (Section 11)

Section 5. Fire-fighting measures

Specific hazards arising from the chemical

Pre-Hybridization Mix In a fire or if heated, a pressure increase will occur and the container may burst.

2X Hybridization Buffer In a fire or if heated, a pressure increase will occur and the container may burst.

DMSO Combustible liquid. In a fire or if heated, a pressure increase will occur and the container may burst, with the risk of a subsequent explosion. The vapor/gas is heavier than air and will spread along the ground.Vapors may accumulate in low or confined areas or travel a considerable distance to a source of ignition and flash back. Runoff to sewer may create fire or explosion hazard.

Nuclease-Free Water In a fire or if heated, a pressure increase will occur and the container may burst.

Stain Cocktail 1 In a fire or if heated, a pressure increase will occur and the container may burst.

Stain Cocktail 2 In a fire or if heated, a pressure increase will occur and the container may burst.

Array Holding Buffer In a fire or if heated, a pressure increase will occur and the container may burst.

Pre-Hybridization Mix Use an extinguishing agent suitable for the surrounding fire.

2X Hybridization Buffer Use an extinguishing agent suitable for the surrounding fire.

DMSO Use dry chemical, CO₂, water spray (fog) or foam.Nuclease-Free Water Use an extinguishing agent suitable for the surrounding

fire.Stain Cocktail 1 Use an extinguishing agent suitable for the surrounding

fire.Stain Cocktail 2 Use an extinguishing agent suitable for the surrounding

fire.Array Holding Buffer Use an extinguishing agent suitable for the surrounding

fire.Wash Buffer A Use an extinguishing agent suitable for the surrounding

fire.Wash Buffer B Use an extinguishing agent suitable for the surrounding

fire.

Extinguishing media

:

Pre-Hybridization Mix None known.2X Hybridization Buffer None known.DMSO Do not use water jet.Nuclease-Free Water None known.Stain Cocktail 1 None known.Stain Cocktail 2 None known.Array Holding Buffer None known.Wash Buffer A None known.Wash Buffer B None known.

Suitable extinguishing media

:

Unsuitable extinguishing media

:

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Hazardous thermal decomposition products

Pre-Hybridization Mix Decomposition products may include the following materials:carbon dioxidecarbon monoxidenitrogen oxidessulfur oxideshalogenated compoundsmetal oxide/oxides

2X Hybridization Buffer Decomposition products may include the following materials:carbon dioxidecarbon monoxidenitrogen oxidessulfur oxideshalogenated compoundsmetal oxide/oxides

DMSO Decomposition products may include the following materials:carbon dioxidecarbon monoxidesulfur oxides

Nuclease-Free Water No specific data.Stain Cocktail 1 Decomposition products may include the following

materials:carbon dioxidecarbon monoxidenitrogen oxidessulfur oxideshalogenated compoundsmetal oxide/oxides

Stain Cocktail 2 Decomposition products may include the following materials:carbon dioxidecarbon monoxidenitrogen oxidessulfur oxideshalogenated compoundsmetal oxide/oxides

Array Holding Buffer Decomposition products may include the following materials:carbon dioxidecarbon monoxidenitrogen oxidessulfur oxideshalogenated compoundsmetal oxide/oxides

Wash Buffer A Decomposition products may include the following materials:phosphorus oxideshalogenated compoundsmetal oxide/oxides

Wash Buffer B Decomposition products may include the following materials:carbon dioxidecarbon monoxide

Wash Buffer A In a fire or if heated, a pressure increase will occur and the container may burst.

Wash Buffer B In a fire or if heated, a pressure increase will occur and the container may burst.

:

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Pre-Hybridization Mix Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

2X Hybridization Buffer Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

DMSO Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. Move containers from fire area if this can be done without risk. Use water spray to keep fire-exposed containers cool.

Nuclease-Free Water Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

Stain Cocktail 1 Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

Stain Cocktail 2 Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

Array Holding Buffer Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

Wash Buffer A Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

Wash Buffer B Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

nitrogen oxidessulfur oxidesmetal oxide/oxides

Pre-Hybridization Mix Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

2X Hybridization Buffer Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

DMSO Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Nuclease-Free Water Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Stain Cocktail 1 Fire-fighters should wear appropriate protective

Special protective equipment for fire-fighters

:

Special protective actions for fire-fighters

:

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Section 5. Fire-fighting measuresequipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Stain Cocktail 2 Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Array Holding Buffer Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Wash Buffer A Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Wash Buffer B Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Section 6. Accidental release measures

Environmental precautions

Personal precautions, protective equipment and emergency procedures

Stop leak if without risk. Move containers from spill area. Prevent entry into sewers,water courses, basements or confined areas. Wash spillages into an effluent treatment plant or proceed as follows. Contain and collect spillage with non-combustible,absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local regulations (see Section 13). Dispose of via a licensed waste disposal contractor. Note: see Section 1 for emergency contact information and Section 13 for waste disposal.

:

: No action shall be taken involving any personal risk or without suitable training.Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Put on appropriate personal protective equipment.

Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air).

Large spill :

Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble. Alternatively, or if water-insoluble, absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor.

Small spill :

Methods and materials for containment and cleaning up

For non-emergency personnel

For emergency responders : If specialised clothing is required to deal with the spillage, take note of any information in Section 8 on suitable and unsuitable materials. See also the information in "For non-emergency personnel".

Section 7. Handling and storagePrecautions for safe handling

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Section 7. Handling and storage

Advice on general occupational hygiene

Pre-Hybridization Mix Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

2X Hybridization Buffer Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

DMSO Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

Nuclease-Free Water Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face

:

Protective measures Pre-Hybridization Mix Put on appropriate personal protective equipment (see Section 8).

2X Hybridization Buffer Put on appropriate personal protective equipment (see Section 8). Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container.

DMSO Put on appropriate personal protective equipment (see Section 8). Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist. Use only with adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Do not enter storage areas and confined spaces unless adequately ventilated.Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Store and use away from heat, sparks,open flame or any other ignition source. Use explosion-proof electrical (ventilating, lighting and material handling) equipment. Use only non-sparking tools.Empty containers retain product residue and can be hazardous. Do not reuse container.

Nuclease-Free Water Put on appropriate personal protective equipment (see Section 8).

Stain Cocktail 1 Put on appropriate personal protective equipment (see Section 8).

Stain Cocktail 2 Put on appropriate personal protective equipment (see Section 8).

Array Holding Buffer Put on appropriate personal protective equipment (see Section 8).

Wash Buffer A Put on appropriate personal protective equipment (see Section 8).

Wash Buffer B Put on appropriate personal protective equipment (see Section 8).

:

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Section 7. Handling and storage

Conditions for safe storage,including any incompatibilities

before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

Stain Cocktail 1 Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

Stain Cocktail 2 Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

Array Holding Buffer Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

Wash Buffer A Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

Wash Buffer B Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

Pre-Hybridization Mix Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry,cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Keep container tightly closed and sealed until ready for use.Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

2X Hybridization Buffer Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry,cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Keep container tightly closed and sealed until ready for use.Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

DMSO Store in accordance with local regulations. Store in a

:

15/31


Section 7. Handling and storagesegregated and approved area. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink.Eliminate all ignition sources. Separate from oxidizing materials. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Nuclease-Free Water Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry,cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Keep container tightly closed and sealed until ready for use.Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Stain Cocktail 1 Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry,cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Keep container tightly closed and sealed until ready for use.Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Stain Cocktail 2 Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry,cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Keep container tightly closed and sealed until ready for use.Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Array Holding Buffer Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry,cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Keep container tightly closed and sealed until ready for use.Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Wash Buffer A Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry,cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Keep container tightly closed and sealed until ready for use.Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

Wash Buffer B Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry,cool and well-ventilated area, away from incompatible

16/31


Section 7. Handling and storagematerials (see Section 10) and food and drink. Keep container tightly closed and sealed until ready for use.Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

DMSOdimethyl sulfoxide AIHA WEEL (United States, 10/2011).

TWA: 250 ppm 8 hours.

Section 8. Exposure controls/personal protection

Ingredient name Exposure limits

Hand protection

Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator.

Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary.

Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists,gases or dusts. If contact is possible, the following protection should be worn, unless the assessment indicates a higher degree of protection: safety glasses with side-shields.

Eye/face protection

Respiratory protection :

:

:

Body protection Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product.

:

Environmental exposure controls

: Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

Appropriate engineering controls

: Good general ventilation should be sufficient to control worker exposure to airborne contaminants.

Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period.Appropriate techniques should be used to remove potentially contaminated clothing.Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location.

Hygiene measures :

Control parameters

Individual protection measures

Occupational exposure limits

Skin protection

Other skin protection : Appropriate footwear and any additional skin protection measures should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product.

17/31


Section 9. Physical and chemical propertiesPre-Hybridization Mix Liquid.2X Hybridization Buffer Liquid.DMSO Liquid. [Hygroscopic.]Nuclease-Free Water Liquid.Stain Cocktail 1 Liquid.Stain Cocktail 2 Liquid.Array Holding Buffer Liquid.Wash Buffer A Liquid.Wash Buffer B Liquid.

Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO Not available.Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.

Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO Colorless. Clear.Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.

Physical state

Odor

Color

:

:

:

Flash point : Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO Closed cup: 87°C (188.6°F)

Open cup: 87°C (188.6°F)Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.

Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO 300 to 302°C (572 to 575.6°F)Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.

:Auto-ignition temperature

Flammable limits : Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO Lower: 2.6%

Upper: 28.5%Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.

18/31


Section 9. Physical and chemical properties

Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO 189°C (372.2°F)Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.


Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO 18.5°C (65.3°F)Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.

Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO 1.1Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.

Pre-Hybridization Mix Not applicable.2X Hybridization Buffer Not applicable.DMSO 78.14 g/moleNuclease-Free Water Not applicable.Stain Cocktail 1 Not applicable.Stain Cocktail 2 Not applicable.Array Holding Buffer Not applicable.Wash Buffer A Not applicable.Wash Buffer B Not applicable.

Boiling/condensation point

Melting/freezing point

Molecular weight

pH

Relative density

Pre-Hybridization Mix Not applicable.2X Hybridization Buffer Not applicable.DMSO C2-H6-O-SNuclease-Free Water Not applicable.Stain Cocktail 1 Not applicable.Stain Cocktail 2 Not applicable.Array Holding Buffer Not applicable.Wash Buffer A Not applicable.Wash Buffer B Not applicable.

Molecular formula

:

:

:

:

:

:

19/31


Section 9. Physical and chemical properties


Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO 2.7 [Air = 1]Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.

Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO 0.056 kPa (0.42 mm Hg) [room temperature]Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.


Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO 0.026 (butyl acetate = 1)Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.

Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.dimethyl sulfoxide Dynamic (room temperature): 2.14 mPa·s (2.14 cP)Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.

Vapor pressure

Vapor density

Volatility

Evaporation rate

Viscosity

Solubility

:

:

:

:

:

:

20/31


Section 9. Physical and chemical propertiesPre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO Not available.Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.

Physical/chemical properties comments

:

Section 10. Stability and reactivity

Pre-Hybridization Mix The product is stable.2X Hybridization Buffer The product is stable.DMSO The product is stable.Nuclease-Free Water The product is stable.Stain Cocktail 1 The product is stable.Stain Cocktail 2 The product is stable.Array Holding Buffer The product is stable.Wash Buffer A The product is stable.Wash Buffer B The product is stable.

Chemical stability :

Possibility of hazardous reactions

: Pre-Hybridization Mix Under normal conditions of storage and use, hazardous reactions will not occur.

2X Hybridization Buffer Under normal conditions of storage and use, hazardous reactions will not occur.

DMSO Under normal conditions of storage and use, hazardous reactions will not occur.

Nuclease-Free Water Under normal conditions of storage and use, hazardous reactions will not occur.

Stain Cocktail 1 Under normal conditions of storage and use, hazardous reactions will not occur.

Stain Cocktail 2 Under normal conditions of storage and use, hazardous reactions will not occur.

Array Holding Buffer Under normal conditions of storage and use, hazardous reactions will not occur.

Wash Buffer A Under normal conditions of storage and use, hazardous reactions will not occur.

Wash Buffer B Under normal conditions of storage and use, hazardous reactions will not occur.

Reactivity : Pre-Hybridization Mix No specific test data related to reactivity available for this product or its ingredients.

2X Hybridization Buffer No specific test data related to reactivity available for this product or its ingredients.

DMSO No specific test data related to reactivity available for this product or its ingredients.

Nuclease-Free Water No specific test data related to reactivity available for this product or its ingredients.

Stain Cocktail 1 No specific test data related to reactivity available for this product or its ingredients.

Stain Cocktail 2 No specific test data related to reactivity available for this product or its ingredients.

Array Holding Buffer No specific test data related to reactivity available for this product or its ingredients.

Wash Buffer A No specific test data related to reactivity available for this product or its ingredients.

Wash Buffer B No specific test data related to reactivity available for this product or its ingredients.

21/31


Section 10. Stability and reactivity

Hazardous decomposition products

Conditions to avoid Pre-Hybridization Mix No specific data.2X Hybridization Buffer No specific data.DMSO Avoid all possible sources of ignition (spark or flame).

Do not pressurize, cut, weld, braze, solder, drill, grind or expose containers to heat or sources of ignition. Do not allow vapor to accumulate in low or confined areas.

Nuclease-Free Water No specific data.Stain Cocktail 1 No specific data.Stain Cocktail 2 No specific data.Array Holding Buffer No specific data.Wash Buffer A No specific data.Wash Buffer B No specific data.

Pre-Hybridization Mix Under normal conditions of storage and use, hazardous decomposition products should not be produced.

2X Hybridization Buffer Under normal conditions of storage and use, hazardous decomposition products should not be produced.

DMSO Under normal conditions of storage and use, hazardous decomposition products should not be produced.

Nuclease-Free Water Under normal conditions of storage and use, hazardous decomposition products should not be produced.

Stain Cocktail 1 Under normal conditions of storage and use, hazardous decomposition products should not be produced.

Stain Cocktail 2 Under normal conditions of storage and use, hazardous decomposition products should not be produced.

Array Holding Buffer Under normal conditions of storage and use, hazardous decomposition products should not be produced.

Wash Buffer A Under normal conditions of storage and use, hazardous decomposition products should not be produced.

Wash Buffer B Under normal conditions of storage and use, hazardous decomposition products should not be produced.

Pre-Hybridization Mix No specific data.2X Hybridization Buffer No specific data.DMSO Reactive or incompatible with the following materials:

oxidizing materialsNuclease-Free Water No specific data.Stain Cocktail 1 No specific data.Stain Cocktail 2 No specific data.Array Holding Buffer No specific data.Wash Buffer A No specific data.Wash Buffer B No specific data.

:

:

Incompatible materials :

Section 11. Toxicological information

Acute toxicity

Pre-Hybridization Mixsodium chloride LD50 Oral Rat 3000 mg/kg -

2X Hybridization Buffersodium chloride LD50 Oral Rat 3000 mg/kg -

DMSOdimethyl sulfoxide LD50 Dermal Rat 40000 mg/kg -

Product/ingredient name Result Species Dose Exposure

Information on toxicological effects

22/31


Section 11. Toxicological informationLD50 Oral Rat 14500 mg/kg -

Stain Cocktail 1sodium chloride LD50 Oral Rat 3000 mg/kg -

Stain Cocktail 2sodium chloride LD50 Oral Rat 3000 mg/kg -

Array Holding Buffersodium chloride LD50 Oral Rat 3000 mg/kg -

Wash Buffer Asodium chloride LD50 Oral Rat 3000 mg/kg -

Irritation/Corrosion

Pre-Hybridization Mixsodium chloride Eyes - Moderate irritant Rabbit - 24 hours 100

milligrams-

Eyes - Moderate irritant Rabbit - 10 milligrams -Skin - Mild irritant Rabbit - 24 hours 500

milligrams-

2X Hybridization Buffersodium chloride Eyes - Moderate irritant Rabbit - 24 hours 100

milligrams-


milligrams-

DMSOdimethyl sulfoxide Eyes - Mild irritant Rabbit - 24 hours 500

milligrams-

Eyes - Mild irritant Rabbit - 100 milligrams

-

Skin - Mild irritant Rabbit - 24 hours 500 milligrams

-

Skin - Mild irritant Rabbit - 100 milligrams

-

Stain Cocktail 1sodium chloride Eyes - Moderate irritant Rabbit - 24 hours 100

milligrams-


milligrams-

Stain Cocktail 2sodium chloride Eyes - Moderate irritant Rabbit - 24 hours 100

milligrams-


milligrams-

Array Holding Buffersodium chloride Eyes - Moderate irritant Rabbit - 24 hours 100

milligrams-

Eyes - Moderate irritant Rabbit - 10 milligrams -Skin - Mild irritant Rabbit - 24 hours 500 -

Product/ingredient name Result Score Exposure ObservationSpecies

23/31



Carcinogenicity

Not available.

Mutagenicity

Not available.

Teratogenicity

Not available.

Reproductive toxicity

Not available.

milligrams

Wash Buffer Asodium chloride Eyes - Moderate irritant Rabbit - 24 hours 100

milligrams-


milligrams-

Sensitization

Not available.

Information on the likely routes of exposure

Inhalation :

:Ingestion

Skin contact :

:Eye contact

Symptoms related to the physical, chemical and toxicological characteristics

Skin contact

Ingestion

Inhalation

:

:

:

Eye contact :

Delayed and immediate effects and also chronic effects from short and long term exposure

Specific target organ toxicity (single exposure)

Specific target organ toxicity (repeated exposure)

Not available.

Not available.

Aspiration hazard

Not available.

: Not available.

Potential acute health effects

Potential immediate effects

: Not available.

Short term exposure

Potential delayed effects : Not available.

Long term exposure

24/31



Not available.

General :

Carcinogenicity :

Mutagenicity :

Teratogenicity :

Developmental effects :

Fertility effects :

Potential chronic health effects

Other information :

Numerical measures of toxicity

Pre-Hybridization MixOral 58004.6 mg/kg

2X Hybridization BufferOral 25753 mg/kg

Stain Cocktail 1Oral 55437 mg/kg

Stain Cocktail 2Oral 55497 mg/kg

Array Holding BufferOral 55497 mg/kg

Wash Buffer AOral 57038.6 mg/kg

Route ATE value

Acute toxicity estimates

Interactive effects :

Potential immediate effects

:

Potential delayed effects :

Section 12. Ecological informationToxicity

Pre-Hybridization Mixsodium chloride Acute EC50 2430000 µg/l Fresh water Algae - Navicula seminulum 96 hours

Acute EC50 28.85 mg/dm3 Fresh water Algae - Pseudokirchneriella subcapitata

72 hours

Acute EC50 519.6 mg/l Fresh water Crustaceans - Cypris subglobosa 48 hoursAcute EC50 402600 µg/l Fresh water Daphnia - Daphnia magna 48 hoursAcute IC50 6.87 g/L Fresh water Aquatic plants - Lemna minor 96 hoursAcute LC50 1000000 µg/l Fresh water Fish - Morone saxatilis - Larvae 96 hoursChronic NOEC 6 g/L Fresh water Aquatic plants - Lemna minor 96 hoursChronic NOEC 0.314 g/L Fresh water Daphnia - Daphnia pulex 21 daysChronic NOEC 100 mg/l Fresh water Fish - Gambusia holbrooki - Adult 8 weeks

Product/ingredient name SpeciesResult Exposure

25/31


Section 12. Ecological information

2X Hybridization Buffersodium chloride Acute EC50 2430000 µg/l Fresh water Algae - Navicula seminulum 96 hours


72 hours


DMSOdimethyl sulfoxide Acute LC50 25000 ppm Fresh water Daphnia - Daphnia magna -

Neonate48 hours

Acute LC50 34000000 µg/l Fresh water Fish - Pimephales promelas 96 hoursChronic NOEC <0.1 g/L Fresh water Fish - Danio rerio - Embryo 30 days

Stain Cocktail 1sodium chloride Acute EC50 2430000 µg/l Fresh water Algae - Navicula seminulum 96 hours


72 hours


Stain Cocktail 2sodium chloride Acute EC50 2430000 µg/l Fresh water Algae - Navicula seminulum 96 hours


72 hours


Array Holding Buffersodium chloride Acute EC50 2430000 µg/l Fresh water Algae - Navicula seminulum 96 hours


72 hours


Wash Buffer Asodium chloride Acute EC50 2430000 µg/l Fresh water Algae - Navicula seminulum 96 hours


72 hours

26/31


Section 12. Ecological information

Mobility :

LogPow BCF Potential

Bioaccumulative potential

Other adverse effects : No known significant effects or critical hazards.

Product/ingredient name

DMSOdimethyl sulfoxide -1.35 3.16 low

Nuclease-Free Waterwater -1.38 - low


Persistence and degradability

Soil/water partition coefficient (KOC)

: Pre-Hybridization Mix Not available.2X Hybridization Buffer Not available.DMSO Not available.Nuclease-Free Water Not available.Stain Cocktail 1 Not available.Stain Cocktail 2 Not available.Array Holding Buffer Not available.Wash Buffer A Not available.Wash Buffer B Not available.

Mobility in soil

Not available.

Section 13. Disposal considerationsThe generation of waste should be avoided or minimized wherever possible. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Waste should not be disposed of untreated to the sewer unless fully compliant with the requirements of all authorities with jurisdiction.Waste packaging should be recycled. Incineration or landfill should only be considered when recycling is not feasible. This material and its container must be disposed of in a safe way. Empty containers or liners may retain some product residues. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers.

:Disposal methods

27/31


Section 14. Transport information

-

-

-

-

-

-

-

Not regulated.

-

-

Not regulated. Not regulated.

- - -

DOT Classification

IMDG IATA

UN number

UN proper shipping name

Transport hazard class(es)

Packing group

Additional information

Environmental hazards

Special precautions for user

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

No. No. No.

Transport within user’s premises: always transport in closed containers that are upright and secure. Ensure that persons transporting the product know what to do in the event of an accident or spillage.

: Not available.

:

TDG Classification

Not regulated.

-

-

-

No.

-

ADR/RID

Not regulated.

-

-

-

No.

-

Mexico Classification

Not regulated.

-

-

-

No.

-

Section 15. Regulatory informationU.S. Federal regulations

Clean Water Act (CWA) 311: Phosphoric acid, disodium salt, heptahydrate; disodium hydrogenorthophosphate

:

Clean Air Act Section 112(b) Hazardous Air Pollutants (HAPs)

: Not listed

Clean Air Act Section 602 Class I Substances

: Not listed

Clean Air Act Section 602 Class II Substances

: Not listed

DEA List I Chemicals (Precursor Chemicals)

: Not listed

DEA List II Chemicals (Essential Chemicals)

: Not listed

TSCA 8(a) CDR Exempt/Partial exemption: Not determined

United States inventory (TSCA 8b): Not determined.

SARA 302/304

Composition/information on ingredients

28/31


Section 15. Regulatory information

None of the components are listed.Massachusetts :

New York : None of the components are listed.

State regulations

SARA 304 RQ : 4547290.9 lbs / 2064470.1 kg

Pre-Hybridization Mixsodium azide 0 - 1 Yes. 500 - 1000 -

2X Hybridization Buffersodium azide 0 - 1 Yes. 500 - 1000 -

Stain Cocktail 1sodium azide 0 - 1 Yes. 500 - 1000 -

Stain Cocktail 2sodium azide 0 - 1 Yes. 500 - 1000 -

Array Holding Buffersodium azide 0 - 1 Yes. 500 - 1000 -

Wash Buffer Asodium azide 0 - 1 Yes. 500 - 1000 -

Wash Buffer Bsodium azide 0 - 1 Yes. 500 - 1000 -

Name % EHS (lbs) (lbs)(gallons) (gallons)

SARA 302 TPQ SARA 304 RQ

SARA 311/312

Classification : Not applicable.

Pre-Hybridization Mixsodium chloride 1 - 10 No. No. No. Yes. No.

2X Hybridization Buffersodium chloride 10 - 25 No. No. No. Yes. No.

DMSOdimethyl sulfoxide 100 Yes. No. No. Yes. No.

Stain Cocktail 1sodium chloride 1 - 10 No. No. No. Yes. No.

Stain Cocktail 2sodium chloride 1 - 10 No. No. No. Yes. No.

Array Holding Buffersodium chloride 1 - 10 No. No. No. Yes. No.

Wash Buffer Asodium chloride 1 - 10 No. No. No. Yes. No.

Name % Fire hazard

Sudden release of pressure

Reactive Immediate (acute)health hazard

Delayed (chronic)health hazard

Composition/information on ingredients

29/31


Section 15. Regulatory informationNew Jersey : None of the components are listed.

Pennsylvania : None of the components are listed.

International regulations

Chemical Weapon Convention List Schedules I, II & III Chemicals

Montreal Protocol (Annexes A, B, C, E)

Not listed.

Stockholm Convention on Persistent Organic Pollutants

Not listed.

Rotterdam Convention on Prior Inform Consent (PIC)

Not listed.

Not listed.

UNECE Aarhus Protocol on POPs and Heavy Metals

Not listed.

None of the components are listed.

WHMIS (Canada) Pre-Hybridization Mix Not controlled under WHMIS (Canada).2X Hybridization Buffer Not controlled under WHMIS (Canada).DMSO Class B-3: Combustible liquid with a flash point between

37.8°C (100°F) and 93.3°C (200°F).Nuclease-Free Water Not controlled under WHMIS (Canada).Stain Cocktail 1 Not controlled under WHMIS (Canada).Stain Cocktail 2 Not controlled under WHMIS (Canada).Array Holding Buffer Not controlled under WHMIS (Canada).Wash Buffer A Not controlled under WHMIS (Canada).Wash Buffer B Not controlled under WHMIS (Canada).

:

Canada

Canadian NPRI :

Canada inventory : Not determined.

CEPA Toxic substances : None of the components are listed.

Canadian lists

Section 16. Other information

History

Date of issue/Date of revision

Date of previous issue

:

:

08/11/2015.

08/08/2014.

Hazardous Material Information System (U.S.A.)

0

0

0

00

2

National Fire Protection Association (U.S.A.)

Health

Special

Instability/Reactivity

Flammability

Health

Flammability

Physical hazards

The customer is responsible for determining the PPE code for this material.

30/31


Section 16. Other informationVersion

To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein.Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.

Notice to reader

:

Indicates information that has changed from previously issued version.

Key to abbreviations : ATE = Acute Toxicity EstimateBCF = Bioconcentration FactorGHS = Globally Harmonized System of Classification and Labelling of ChemicalsIATA = International Air Transport AssociationIBC = Intermediate Bulk ContainerIMDG = International Maritime Dangerous GoodsLogPow = logarithm of the octanol/water partition coefficientMARPOL 73/78 = International Convention for the Prevention of Pollution From Ships,1973 as modified by the Protocol of 1978. ("Marpol" = marine pollution)UN = United Nations

2

31/31

SAFETY DATA SHEET - Thermo Fisher · 2016. 11. 4. · GeneChip® Hybridization, Wash and Stain Kit Not available. SAFETY DATA SHEET GHS product identifier Other means of identification

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