CONTINENTAL BREAKFAST Mechanisms underlying gene silencing by microRNAs miRNAs protect us against pathogenic RNA RNA-seq of differentiation, a few cells and a few hours at a time 8:30 am 8:45 am Ian MacRae Scripps 9:35 am Irene Pedersen UC Irvine 10:00 am Ali Mortazavi UC Irvine Regulation of RNA activity by mRNA methylation in stem cells Deciphering the poly(A) code Transcriptomic signatures in neurodegenerative disease The non-template functions of telomerase RNA 1:00 pm Crystal Zhao Sanford-Burnham 1:50 pm Yongsheng Shi UC Irvine 2:15 pm Ryan Lim UC Irvine 2:40 pm Feng Qiao UC Irvine Structural imprints in vivo decode RNA regulatory mechanisms Embracing splicing complexity: integrating mechanisms of splice site selection to predict splicing patterns lncRNAs: function and mechanism in controlling cellular identity 3:20 pm Robert Spitale UC Irvine 3:45 pm Klemens Hertel UC Irvine 4:10 pm Mitchell Guttman Caltech RNA Symposium Co-Sponsored by: UCI Institute for Genomics & Bioinformatics UCI Genomics High-Throughput Facility UCI Department of Pharmaceutical Sciences UCI Data Science Initiative UCI Department of Molecular Biology and Biochemistry Telomerase RNA LUNCH BREAK COFFEE BREAK rsvp: [email protected] April 24, 2015 Calit2 Building Auditorium WINE AND CHEESE RECEPTION RNA editing enzyme machines Repeat-containing RNA binding proteins: switches, blocks, and triggers Functions of a liver-specific microRNA in the life cycle of hepatitis C virus 10:40 am Ruslan Afasizhev Boston University 11:05 am Inna Afasizheva Boston University 11:30 am Peter Sarnow Stanford University COFFEE BREAK