Risk factors of the steroid induced ocular hypertension after corneal refractive surgery Kyoung Min Lee, MD 1,2 , Won Ryang Wee 1,2 , Jin Hak Lee 1,3 , Mee Kum Kim, MD 1,2 1 Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea 2 Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea, 3 Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea Authors have no financial interests
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Risk factors of the steroid induced ocular hypertension after corneal refractive surgery
Risk factors of the steroid induced ocular hypertension after corneal refractive surgery. Kyoung Min Lee, MD 1,2 , Won Ryang Wee 1,2 , Jin Hak Lee 1,3 , Mee Kum Kim, MD 1,2 1 Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea - PowerPoint PPT Presentation
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Risk factors of the steroid induced ocular hypertension after corneal refractive surgery
Kyoung Min Lee, MD1,2, Won Ryang Wee1,2, Jin Hak Lee1,3, Mee Kum Kim, MD1,2
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea
2 Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea,
3Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea
Authors have no financial interests
PurposeSteroid induced glaucoma
-prolonged steroid use-myopia
Corneal refractive surgery
-changes in corneal thickness-IIOP could be masked
David Rex Hamilton et al.Ophthalmology 2002; 109:659-
665
To investigate the changes of IOP after corneal refractive surgery To determine the risk factors
of steroid induced increased IOP
Methods• Inclusion
– 2004. 1 ~ 2008. 1– Corneal refractive surgery in SNUH
• Eximer laser• PRK• LASIK• LASEK
• Exclusion– Follow up less than 1 month– Refractive surgery in single eye for the eldlery– Hyperopia
225 patients, 450 eyes
Retrospective
Methods• Steroids– Normal
• 0.1% fluometholone (flarex) for 1week
• 0.1% fluometholone (ocumetholone) tapering
– DLK• 1% prednisolone (Pred
Forte)
– Myopic regression• 1% prednisolone (Pred
Forte)
• IOP– Pneumatic tonometer
– Sheng-Yao Hsu et al.– J Cataract Refract
Surg 2009;35:76-82– Adjusted baseline
IOP• 4.8mmHg / 100μm
– Hornova J et al.– Cesk Slov Oftalmol
2000;56:98-103
Methods• Definition of IIOP– Increase of IOP• More than 130% of adjusted baseline IOP• After 1 week• Repeated more than two times
– Need of medication• With evidence of IOP increase