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Rheumatologic Emergencies
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Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Dec 28, 2015

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Norma Sutton
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Page 1: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Rheumatologic Emergencies

Page 2: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

RHEUM EMERGENCIES

• Life or organ threatening if not recognized within several hours or days

• Conditions that won’t first present to a Rheumatologist…..

Page 3: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Case

• 24 yo female with hx of initial left knee swelling, then right knee swelled

• Also tenosynovitis of wrist

• Asp knee 53,000 WBC

• Gram stain negative

Page 4: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

PYOGENIC ARTHRITIS

Bacterial joint space infections are far more destructive than viral or fungal…..

Page 5: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

INFECTIOUS (PYOGENIC) ARTHRITIS

• Assume any monoarticular arthritis is infectious until proven otherwise

• Sudden onset and very painful is more suggestive of crystalline dz – bacterial infection peaks over a few days

• If a nearby break in skin, or bacteremia, most definitely approach as infectious process

• Septic joint carries high morbidity and mortality

• Inflammatory arthritis can mimic septic joint!

Page 6: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

INFECTIOUS (PYOGENIC) ARTHRITIS

• Risk Factors:– Bacteremia– Adjacent osteomyelitis– Soft tissue infection– Recent injection/aspiration– Penetrating trauma – foreign body

• Differential:– Crystalline– Mono presentation of a polyarticular disease

Page 7: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.
Page 8: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

INFECTIOUS (PYOGENIC) ARTHRITIS

• Approach

– ASPIRATE – culture, gram stain, cell count– > 30,000 would be concerning for infection– Don’t let the presence of crystals fool you– Don’t let scans replace aspiration – Films most likely will be normal – early on– Blood cultures

Page 9: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

INFECTIOUS (PYOGENIC) ARTHRITIS

Page 10: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

INFECTIOUS (PYOGENIC) ARTHRITIS

• Treat while cultures are pending

– #1 bug - S. aureus– Other bugs include:

• H. flu in kids < than 3 yo• Beta strep in neonates• Various other strep in adults• S. epidermidis and GNR in prosthetic joints• Pseudomonas in IVDA• Salmonella in sickle cell disease

Page 11: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Septic Arthritis

• Staph aureus: Healthy adults, skin breakdown, damaged or replaced joints

• Strep Species: Healthy adults, asplenic

• Neisseria gonorrhea: Sexually active young adults, tenosynovitis

• Gram Negative: Immunocompromised hosts, GI infections

Page 12: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

INFECTIOUS (PYOGENIC) ARTHRITIS

• Treatment Recommendations:

– MRSA is a problem => vancomycin– Gram pos => nafcillin – GNR => 3rd gen ceph, add an AG if pseudomonas– Nothing on gram stain => ceftriaxone or cefotaxime– Prosthetic joint => vanco + ciprofoxacin

Page 13: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

DGI

Not truly an“emergency” buta condition youwould not want to miss…

Page 14: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

DISSEMINATED GONORRHEA

• Most common cause of septic arthritis and tenosynovitis in young adults in N.A.

• Complicates less than 1% of all GC cases

• Often have an asymptomatic mucosal infection

• Major risk factor is absence of C5-8 complement (….remember this for boards)

Page 15: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

DGI

Page 16: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

DISSEMINATED GONORRHEA

• Clues:– Migratory or additive acute oligo (<4) arthritis– Tenosynovitis of wrists / ankles / foot– Fever / chills– Females more commonly affected than

males and often within 1 week of menses – 2/3 have rash but it may be scant

Page 17: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

DGI

May have only ONE vesicle orpustule – so look carefully…

Page 18: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

DISSEMINATED GONORRHEA

Page 19: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

DISSEMINATED GONORRHEA

Page 20: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

DISSEMINATED GONORRHEA

• Approach:– Less than 25% of synovial cultures are positive– Less than 10% of blood cultures are positive– Skin biopsy culture is hardly ever positive but may be

able to see on gram stain– Best yield is to cultures/DNA probe the mucosal site– Remember the concomitant infection (HIV, syphilis,

NSU)– Rx with 3rd generation cephalosporin– Often add doxycycline to cover for Chlamydia

Page 21: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Gram Stain of GC

Page 22: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Case

• 53 yo female with hx of SLE c/o acute onset of dyspnea and cough

• Had previously been stable

• Hgb 7.4, PLT 111,

• UA 4+ protein, RBC casts

• ds-DNA >370 (markedly positive)

• ESR 85

Page 23: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

PULMONARY-RENAL SYNDROMES

• Acute GN and pulmonary hemorrhage:

– Goodpasture’s– Wegener’s– SLE– Post-Strep– Churg-Strauss– Microscopic PAN– ANCA-associated vasculitis– APLA Syndrome

Page 24: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

DIFFUSE ALVEOLAR HEMORRHAGE SYNDROME• Capillaritis- Wegener’s, Microscopic PAN,

HSP, Cryoglobulinemia, Behcet’s, SLE, RA, MCTD, Scleroderma, Polymyositis

• Bland Hemorrhage-Goodpasture’s, SLE, Pulmonary hemosiderosis, Mitral stenosis

• Diffuse Alveolar Damage- SLE, Cytotoxic drugs, Cocaine, Infections

Page 25: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

DIFFUSE ALVEOLAR HEMORRHAGE SYNDROME

• Approach:– Bronch – lavage – ANA– ASO/DNase– ANCA (C-WG / P-MPAN)– Anti-GBM

• Treatment:– High dose steroids / cyclophosphamide– Plasmapheresis for Goodpasture’s, possibly SLE

- UA- HRCT

Reminder: ANA and RF are not “screens” for autoimmune diseaseANA simply “rules out” SLE if (-)

Page 26: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Case

• 35 yo with SLE

• New leg paresthesias and increasing bilateral weakness

• Unable to urinate

• New fever

Page 27: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

TRANSVERSE MYELITIS

• Clues:– Leg paresthesias and bilateral weakness– Dermatomal sensory loss– Urinary retention and fecal incontinence– Fever/ axial pain– Abnormal CSF

• Approach:– MRI – diffuse edema– Pulse steroids 1000 mg Solumedrol IV for 3 days

/plasmapheresis /cyclophosphamide

- arteritis of spinal cord- APLA, SLE- hematomas/tumor/fx

Page 28: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.
Page 29: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

CAUDA EQUINA SYNDROME• Ankylosing spondylitis• Spinal / epidural anesthesia• Central herniation / epidural abscess• Dysfunction in multiple

lumbosacral nerve roots• Clues:

– back pain / rectal pain / posterior leg pain– loss of bowel / bladder control or saddle anes– foot drop

• Image and decompress – you have 48 hours!

Page 30: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Cauda Equina Syndrome

Page 31: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Case

• 18 yo male with fever

• Large joint swelling on/off over last week

• Recent sore throat

• New murmur

Page 32: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

What is this rash?

Page 33: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Erythema Marginatumof - ACUTE RHEUMATIC FEVER

Page 34: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

ACUTE RHEUMATIC FEVER

• Post group A strep, Strep pyogenes• Clinical dz is self-limited; valvular dz is not• Clues:

– Migratory, large joint arthritis– Carditis / valvulitis– Erythema marginatum / sub-Q nodules– Fever – Preceding strep infection– CNS involvement (Sydenham’s chorea)

Page 35: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

ACUTE RHEUMATIC FEVER

Page 36: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Mneumonic for Jones’ major criteria

• J – Joint swelling• ♥ - Carditis – 2002 update – get an echo• N - Nodules• E – Erythema Marginatum rash• S – Syndenham’s Chorea

– Minor Criteria - “PREAF”• PR• Elevated ESR/CRP• ASA – DNase going up• Fever

Page 37: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

ARF- Cross Reactivity Between Strep/Human Tissue

• Cell Walls• Plasma

Membranes• Polysaccharides• Cell membranes• M Protein

• Myocardium• Myocardial

membrane• Heart Valves• Caudate/thalmic

neurons• Cardiac Myosin

Page 38: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

ACUTE RHEUMATIC FEVER • Approach:

– EKG (look for prolonged PR)– Echo-heart valves/carditis – CXR– CBC / ESR / ASO / DNase / throat culture

• Not rapid strep

– Rx with high dose ASA and give PCN prophylaxis monthly for 5 years

– Steroids for heart valve involvement

Page 39: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

How Long do you treat?

• 10 YEARS Or until 40 – if carditis progressing

• 10 YEARS or until 21 – if carditis improves

• 5 YEARS or until 21 – no carditis ever

Page 40: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Case

• 72 yo male

• Mild fever and headache

• Arthralgia in shoulders and knees

• Cannot get out of chair easily over last week

• Difficult to eat

• ESR 87

Page 41: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

GIANT CELL ARTERITIS

Page 42: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

GIANT CELL ARTERITIS• Clues:

– > 50 yo– NEW headache (not chronic)– Jaw claudication or arm claudication– Sudden visual loss, diplopia– Systemically ill with many markers of systemic

inflammation, increased A. Phos, Ferr, ESR

• Approach:– TREAT and then biopsy !! – You have 2 weeks to get the biopsy

Page 43: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Treatment

• GCA-High dose prednisone 1 mg/kd or standardly 60-100 mg daily. Continue for several weeks and taper as ESR decreases

• Treatment for over 2 years, mostly chronically at low doses < 5 mg pred qd

• PMR-start with 20 mg prednisone, taper with watching ESR to < 5 mg pred qd

Page 44: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

GIANT CELL ARTERITIS

Page 45: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

GIANT CELL ARTERITIS

Page 46: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

GIANT CELL ARTERITIS

Page 47: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

GCA

Fundus photograph showing optic atrophy secondary to giant cell arteritis

Page 48: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

GCA-PMR SPECTRUM

Page 49: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Navy Trivia

• GEEDUNK – – Ice cream, candy, potato chips and other

assorted junk food– Or even the place where they can be

purchased

Page 50: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Possibilities of origin

• In the 1920's a comic strip character named Harold Teen and his friends spent a great amount of time at Pop's candy store. The store's owner called it The Geedunk for reasons never explained.

• The Chinese word meaning a place of idleness sounds something like gee dung.

• Geedunk is the sound made by a vending machine when it dispenses a soft drink in a cup.

• It may be derived from the German word tunk meaning to dip or sop either in gravy or coffee. Dunking was a common practice in days when bread, not always obtained fresh, needed a bit of tunking to soften it.

• The ge is a German unaccented prefix denoting repetition. • In time it may have changed from getunk to geedunk.

Page 51: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Case

• 64 yo female with 30 year hx of poorly controlled RA

• Paresthesias in extremites with neck movement

• Scheduled for cholecystectomy next week

• From too much Geedunk

Page 52: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

CERVICAL SUBLUXATION WITH RA

Page 53: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

CERVICAL SUBLUXATION WITH RA

Page 54: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

CERVICAL SUBLUXATION WITH RA

• Clues:– Long-standing RA with or without neck pain

• Presentation:– Hyperreflexia / VBI symptoms– Sphincter dysfunction– Sensory findings in extremities– C1-C2 subluxation greater than 9 mm; presence of atlantoaxial

impaction, worse prognosis-neurosurgical evaluation.

• Approach:– Caution in C-spine manipulation– Image (plain films and MRI)

Page 55: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Case – Not Hunky-Dori

Page 56: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

SCLEROMALACIA PERFORANS

Page 57: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

RA EYE INVOLVEMENT

Page 58: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

RHEUMATOID ARTHRITIS EYE DISEASE

• Episcleritis

• Anterior scleritis with corneal melt

• Scleromalacia

• Scleromalacia perforans

Page 59: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

EPISCLERITIS

Page 60: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

SCLERITIS / CORNEAL MELT

Page 61: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

SCLEROMALACIA

Page 62: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Case

• 43 yo female with SLE

• New mental status changes

• Fever, nausea

• Joint Pain

• Bruising

• New thrombocytopenia 43 K, Hgb 8.3

• Creatinine 3.4

Page 63: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

AUTOIMMUNE COAG DISORDERS

• TTP-Neurologic changes, fever, renal failure, thrombocytopenia, microangiopathic hemolytic anemia

• Plasmapheresis, Pulse steroids

• DIC, AIHA• APS Syndrome –

Page 64: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

CATASTROPHIC ANTIPHOLPHOLIPID SYNDROME

-Gangrene of limb-Recurrent fetal loss-Livedo reticularis-Migraine-Renal insufficiency-PHTN-PE / DVT-Neuro deficits-AVN-Endocarditis-:ow plts – (Sneddon’s syndrome is low plts, stroke, and livedo)

Mortality 50%-TX with - anticoagulation/plasmaphesis

Page 65: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

What is this called?

Page 66: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

AUTOIMMUNE COAG DISORDER

Page 67: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Don’t Confuse with:Cutis Marmorata Telangiectatica Congenita

“We believe that cutis marmorata telangiectaticacongenita is a relatively mild condition. The prognosisis usually good, with minor associated anomalies.Improvement of the mottled, vascular pattern is usuallyobserved within 2 years. We recommend careful clinicalexamination of all patients to exclude any associatedanomalies. Patients should be referred to a neurologistor an ophthalmologist only if symptoms are present orif vascular lesions are present around the eyes.”

Arch Dermatol. 1999;135:34-38

Page 68: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Case

• 43 yo female with scleroderma

• Recently was given prednisone for joint pain by PCM

• BP 182/108

• Creatinine 4.3

• Hgb 8.3 helmet cells on smear

Page 69: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

SCLERODERMA RENAL CRISIS

Page 70: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

SCLERODERMA RENAL CRISIS

• Silent renal failure• Cardiac decompensation• HTN (relative)• Microangiopathic hemolytic anemia

Rx with ACE InhibitorCaptopril in increasing doses

Do not stop the ACE

Page 71: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

SCLERODERMA RENAL CRISIS

Page 72: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

SCLERODERMA RENAL CRISIS

Page 73: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

SCLERODERMA RENAL CRISIS

Page 74: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Case

• 24 yo male

• New onset of testicular pain

• Purpuric rash

• New foot drop

• BP 158/108

Page 75: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

SYSTEMIC VASCULITIS

• Mononeuritis multiplex• Glomerulonephritis• Skin infarction / ulceration• Neurologic dysfunction• Multi-organ infarctions

Always think of systemic vasculitis in the setting of multi-organ disease!

Page 76: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Major Vasculitidies

• Polyarteritis Nodosa• Microscopic Polyangiitis• Churg-Strauss Syndrome• Wegener’s Granulomatosis• Cryoglobulinemia

• Start high dose 60-100 mg day• Or pulse steroids 1 gram Solumedrol for 3 days• Add cyclophosphamide to Wegener’s treatment

Page 77: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Case

• 72 yo with ASCVD

• 3 days S/P catheterization

• Complained of blue toes

• Creatinine 2.7

• microhematuria

• Mild eosinophilia

Page 78: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Blue Toes

Page 79: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

CHOLESTEROL EMBOLIC SYNDROME

- Blue toes after an intervention- TIA- ARF- Microhematuria- Fever- Oschemic bowel- Eosinophilia- ESR increased- Heparinization may worsen by releasing clefts from plaques

Page 80: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

The Dreaded Friday afternoon Consult

• 35 year old female• Tearful in office• Total body pain, worst pain of her life• Abdominal pain, urinary urgency issues• Severe Fatigue• Cannot perform ADL’s• Has been to several physicians for these

complaints

Page 81: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

Fibromyalgia Fulminans

• Treatment

• Empathy from the doctor

• Detailed explanation of the condition

• Prescription for slowly increased exercise – Log book– F/u with PCM (that may be you)

Page 82: Rheumatologic Emergencies. RHEUM EMERGENCIES Life or organ threatening if not recognized within several hours or days Conditions that won’t first present.

RHEUMATOLOGIC EMERGENCIES

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