OWNER’S NAME: Clint Long DOG’S NAME: “Honey” Wht Pines Honey Nut Cheery-Oh TEST DATE: May 3rd, 2018 WOLFINESS 1.1% MEDIUM MATERNAL HAPLOTYPE A16/17/99/100 This certifies the authenticity of Honey’s canine genetic background as determined following careful analysis of more than 200,000 genetic markers. LABRADOR RETRIEVER Welcome to the Embark family! Adam Boyko, Ph.D. CHIEF SCIENCE OFFICER Ryan Boyko CHIEF EXECUTIVE OFFICER
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This certifies the authenticity ofHoney’s canine genetic background asdetermined following careful analysisof more than 200,000 genetic markers.
LABRADORRETRIEVER
Welcome to the Embark family!
Adam Boyko, Ph.D.CHIEF SCIENCE OFFICER
Ryan BoykoCHIEF EXECUTIVE OFFICER
“HONEY” WHT PINES HONEY NUT CHEERY-OH
DNA Test Report Test Date: May 3rd, 2018 embk.me/whtpineshoneynutcheeryoh
GENETIC STATSWolfiness: 1.1 % MEDIUM Predicted adult weight: 57 lbs Genetic age: 39 human years
TEST DETAILSKit number: EM-8566585 Swab number: 31001801030834
Registration: AKC SR84529801
“HONEY” WHT PINES HONEY NUT CHEERY-OH
DNA Test Report Test Date: May 3rd, 2018 embk.me/whtpineshoneynutcheeryoh
Fun Fact We’re pretty sure Labradorscame from the island of Newfoundland,and many experts believe that theNewfoundland breed was developed inneighboring Labrador! By ourcalculations, there are 10 times as manyLabradors in North America than thereare people living in Labrador andNewfoundland.
LABRADOR RETRIEVERThe Labrador Retriever has been the most popular AKC breed in the United Statesevery year for the past 25 years. Their origins have been traced to the St. John’s dog,named for the capital city of the Canadian province “Newfoundland and Labrador.”The St. John’s was developed from imported European dogs for fishing and hunting onthe island of Newfoundland in the 18th century. During the 19th century St John’swere bred in England and developed into the Labradors we know and love. Labradorswere recognized as a breed by the British Kennel Club in 1903 and by the AKC in 1917. With their friendly dispositions and weatherproof build, they are terrific family dogsand outdoor companions. Most Labradors are very active with an appetite to match,and need plenty of exercise. Labradors often love to swim. Their double-coatedweather-resistant fur can cause heavy shedding. Great hunting dogs and popularhousehold companions, Labrador Retrievers are also employed as guide dogs andsearch-and-rescue dogs.
RELATED BREEDS
Flat-CoatedRetriever
Sibling breed
Golden Retriever Sibling breed
Chesapeake BayRetriever
Cousin breed
Newfoundland Cousin breed
“HONEY” WHT PINES HONEY NUT CHEERY-OH
DNA Test Report Test Date: May 3rd, 2018 embk.me/whtpineshoneynutcheeryoh
MATERNAL LINE
Through Honey’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. Thismap helps you visualize the routes that her ancestors took to your home. Their story is described below the map.
HAPLOGROUP: A1a
A1a is the most common maternal lineage among Westerndogs. This lineage traveled from the site of dog domesticationin Central Asia to Europe along with an early dog expansionperhaps 10,000 years ago. It hung around in European villagedogs for many millennia. Then, about 300 years ago, some ofthe prized females in the line were chosen as the foundingdogs for several dog breeds. That set in motion a hugeexpansion of this lineage. It's now the maternal lineage of theoverwhelming majority of Mastiffs, Labrador Retrievers andGordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common acrossthe world among village dogs, a legacy of Europeancolonialism.
HAPLOTYPE: A16/17/99/100
Part of the large A1a haplogroup, this common haplotype isfound in village dogs across the globe. Among breed dogs, wefind it most frequently in Labrador Retrievers, Newfoundlands,German Shepherd Dogs, and Golden Retrievers.
Registration: AKC SR84529801
“HONEY” WHT PINES HONEY NUT CHEERY-OH
DNA Test Report Test Date: May 3rd, 2018 embk.me/whtpineshoneynutcheeryoh
TRAITS
E Locus (Mask, Grizzle, Recessive Red) EE
K Locus (Dominant Black) K K
A Locus (Agouti, Sable) a a
D Locus (Dilute, Blue, Fawn) DD
B Locus (Brown, Chocolate, Liver, Red) bb
Coat Color
Furnishings / Improper Coat (RSPO2) II
Long Haircoat (FGF5) GG
Shedding (MC5R) CC
Curly Coat (KRT71) CC
Body Size - IGF1 NN
Body Size - IGF1R GG
Body Size - STC2 TA
Body Size - GHR (E195K) GG
Body Size - GHR (P177L) CC
Other Coat Traits
Body Size
Brachycephaly (BMP3) CC
Natural Bobtail (T) CC
Hind Dewclaws (LMBR1) CC
Blue Eye Color N/N
Altitude Adaptation (EPAS1) GG
Other Body Features
Performance
Genetic Diversity
Inbreeding Coefficient 30% MHC Class II - DLA DRB1No Diversity
MHC Class II - DLA DQA1 and DQB1Low Diversity
Registration: AKC SR84529801
B B
t
“HONEY” WHT PINES HONEY NUT CHEERY-OH
DNA Test Report Test Date: May 3rd, 2018 embk.me/whtpineshoneynutcheeryoh
CLINICAL TRAITSThese clinical genetic traits can inform clinical decisions and diagnoses. These traits do not predict a disease state or increasedrisk for disease. We currently assess one clinical trait: Alanine Aminotransferase Activity.
Alanine Aminotransferase Activity result: Normal
Wht Pines Honey Nut Cheery-Oh has two normal alleles at ALT.
More information on Alanine Aminotransferase Activity: Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most bloodchemistry panels and is known to be a sensitive measure of liver health. Dogs with two ancestral G alleles show "normal" activity.Dogs that have one or two copies of the derived A allele may have lower resting levels of ALT activity, known as "low normal". If yourdog's result is "low normal" then when a blood chemistry panel is being interpreted the values that you and your veterinarianconsider "normal" may need to be adjusted. Please note that neither a "normal" nor a "low normal" result for this predicts a diseasestate or increased risk for liver disease. Moreover, this mutation does not associate with increased levels of ALT: If your dog hashigh ALT levels, please consult your veterinarian.
Registration: AKC SR84529801
“HONEY” WHT PINES HONEY NUT CHEERY-OH
DNA Test Report Test Date: May 3rd, 2018 embk.me/whtpineshoneynutcheeryoh
HEALTHGood news! Honey did not test positive for any of the genetic diseasesthat Embark screens for. 0
AT RISK
0CARRIER
Registration: AKC SR84529801
“HONEY” WHT PINES HONEY NUT CHEERY-OH
DNA Test Report Test Date: May 3rd, 2018 embk.me/whtpineshoneynutcheeryoh
OTHER CONDITIONSGood news! Honey tested clear for 18 genetic conditions that are common in her breed.
Congenital Macrothrombocytopenia (TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)