The Radial Artery Patency Study Investigators Radial Artery and Saphenous Vein Radial Artery and Saphenous Vein Patency more than 5-years Following Patency more than 5-years Following Coronary Artery Bypass Surgery: Coronary Artery Bypass Surgery: Results from the Results from the Randomized Multicentre Randomized Multicentre Radial Artery Patency Radial Artery Patency Study (RAPS) Study (RAPS)
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Results from the Randomized Multicentre Radial Artery Patency Study (RAPS)
Radial Artery and Saphenous Vein Patency more than 5-years Following Coronary Artery Bypass Surgery:. Results from the Randomized Multicentre Radial Artery Patency Study (RAPS). - PowerPoint PPT Presentation
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The Radial Artery Patency Study Investigators
Radial Artery and Saphenous Vein Radial Artery and Saphenous Vein Patency more than 5-years Following Patency more than 5-years Following
Results from the Results from the Randomized Multicentre Randomized Multicentre
Radial Artery Patency Radial Artery Patency Study (RAPS)Study (RAPS)
The Radial Artery Patency Study Investigators
Stephen E. Fremes MD, Saswata Deb MD, Stephen E. Fremes MD, Saswata Deb MD, Steve K. Singh MD, Randi Feder-Elituv Steve K. Singh MD, Randi Feder-Elituv BSc, Andreas Laupacis MD and Eric A. BSc, Andreas Laupacis MD and Eric A.
Cohen MD for the Radial Artery Patency Cohen MD for the Radial Artery Patency Study InvestigatorsStudy Investigators
April 4, 2001April 4, 2001
New Orleans, LANew Orleans, LA
The Radial Artery Patency Study Investigators
BackgroundBackground Graft patency is a key determinant of
long term outcome following coronary artery bypass surgery (CABG)
The internal thoracic artery provides better long-term patency than the saphenous vein for CABG, prompting surgeons to consider additional arterial grafts, including the radial artery
The Radial Artery Patency Study Investigators
The Radial Artery Patency Study Investigators
Study QuestionStudy Question
Is the patency of the radial Is the patency of the radial artery superior to the artery superior to the saphenous vein at one saphenous vein at one
Intention to Treat AnalysisIntention to Treat Analysis
NEJM Nov. 25, 2004
The Radial Artery Patency Study Investigators
LimitationsLimitations The study design restricted our ability The study design restricted our ability
to evaluate the clinical consequences to evaluate the clinical consequences of radial and saphenous grafts.of radial and saphenous grafts.
The patients recruited into the study The patients recruited into the study were young, and generally low risk.were young, and generally low risk.
The Radial Artery Patency Study Investigators
Conclusions: 5 Year Conclusions: 5 Year ResultsResults Radial arteries are associated with Radial arteries are associated with
reduced rates of functional and reduced rates of functional and complete graft occlusion than complete graft occlusion than saphenous veins. saphenous veins.
Radial arteries are associated with Radial arteries are associated with less graft disease than saphenous less graft disease than saphenous veins.veins.
The Radial Artery Patency Study Investigators
Clinical Trials of Radial Clinical Trials of Radial PatencyPatency
RAPS, Multi-centre, 561 patients, within-patient randomization, Radial vs SVG to RCA or Cx, NEJM 2004
ISRS (Italy) Single centre, 60 ISRS patients and 60 controls, RA, RITA or SVG to OM1 Circulation 2005; 112(supp I):I-265-9
RSVP (UK) Single centre, 142 patients, Radial vs SVG to Cx, Circulation 2008; 117: 2859 - 2864
VA Trial, Multi-centre, 757 patients, Radial vs SVG to 2nd largest coronary, JAMA 2011
RAPCO (Australian), Single centre, 619 patients, <70 years, Radial vs free RITA to 2nd largest coronary >70 years, Radial vs SVG to 2nd largest coronary 4 manuscripts published concerning “interim” results
The Radial Artery Patency Study Investigators
Additional slides
1 year and 5 year results for patients with both studies
Actuarial survival Mace, including adjudicated outcomes Slide including all of the participants