REPUBLIC OF TURKEY MINISTRY OF HEALTH Tuberculosis Control Deaprtment Feyzullah GÜMÜŞLÜ, MD, Specialist Head of TB Control Department Diagnosis and Treatment of Tuberculosis New Methods in TB bacteriological Diagnosis 23 April 2008 – Hall 2 Kurs Programı
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REPUBLIC OF TURKEY MINISTRY OF HEALTH Tuberculosis Control Deaprtment
REPUBLIC OF TURKEY MINISTRY OF HEALTH Tuberculosis Control Deaprtment. Kurs Programı. Feyzullah GÜMÜŞLÜ, MD, Specialist Head of TB Control Department. Diagnosis and Treatment of Tuberculosis New Methods in TB bacteriological Diagnosis 23 April 2008 – Hall 2. Diagnosis of Tuberculosis. - PowerPoint PPT Presentation
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Adavantages Material supply Easy Results in 1 hour Simple technology Considerably
inexpensive
DisadvantagesSensitivityLow in Ss(-) casesDistinction of LTB and active TB is difficultDistinction of TB/MOTT bacilli is difficult
Phage method
Advantages Results in 48-72 hours No need for complex
equipment High sensitivity in
Ss(+) and semi-quantitative results
70% sensitivity and 99% specivity in new cases
Disadvantages Low sensitivity in Ss(-), c(+); Requires expert staffLimited to sputum
Cytotoxin Assay
Advantages Single sample More objective as compared to
Ppd TB/MOTT bacilli distinction
DisadvantagesOnly just obtained blood samples are eligableDifficult to distinguish infection and diseaseExpensive
FINAL REMARKS
Numerous methods have been used and recommended both for smear and culture. However none of them has been granted as the universal best option. Because the applicability of methods depend on technical capacity, trained laboratory staff, appropriate equipment and calibration.