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Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 [email protected]
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Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 [email protected].

Dec 22, 2015

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Page 1: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Railroad Worker Excessive Daytime Sleepiness Study

Benjamin Gerson M.D.University Services

Philadelphia, PA 19154

[email protected]

Page 2: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

UNIVERSITY SERVICESWHO WE ARE

MULTI-SPECIALTY MEDICAL SERVICES

TOXICOLOGY

FORENSIC: EMPLOYEE DRUG TESTING

CLINICAL

SLEEP DISORDERS / NEUROPHYSIOLOGY

CLINICAL RESEARCH

CONSULTING & LITIGATION SUPPORT

Page 3: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Goal of Study

Assess the risk for excessive daytime sleepiness (EDS) and Sleep Apnea in selected workers in safety sensitive positions

Demonstrate that a study can be executed successfully

Page 4: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Method

Screen:

Employees in selected safety sensitive positions due for re-certification were offered the opportunity to complete a [Epworth] Sleepiness Scale

The survey was mailed, faxed, or completed on-line

Scores of 10 or higher classified as “at risk”

Confirm:

Some of the at risk were tested by ambulatory device

Page 5: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Participant Method of Response

Page 6: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Sleepiness Score Distribution

Page 7: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Risk Percentage of EDS

Page 8: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Percentage of Subjects By Age

Page 9: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Summary of Sleepiness Scores by Age

Age Group n Mean SS Score

Std. Dev.

18-30 39 8.79 4.3331-44 168 8.85 4.4045-55 163 9.24 4.64≥ 56 62 7.50 4.53

Page 10: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Percentage of Subjects By Gender

Page 11: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Percentage of Subjects by Race

Page 12: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Participants by Position

Page 13: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Participants by Position

Page 14: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Number at Risk By Job Position

Page 15: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Comparison

Page 16: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Follow-Up Survey

A letter with a follow-up questionnaire was mailed to all participants who screened at risk

Participant was asked to follow-up with physician and then complete the questions

17 [10%] returned the follow-up survey

Page 17: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Online Version of Follow-Up Survey

Page 18: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Responses from Follow-Up Survey

Page 19: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Screening Results

There is evidence that the true proportion of participating employees that are at risk (SS ≥10) is greater than 35%. We can say with 95% confidence that the true proportion is contained within the interval (35.4%, 44.8%).

There is no evidence of a direct linear relationship between SS and age. There also is not enough evidence to show that age group was related to SS scores.

It will be difficult to make any conclusions about gender or race due to the subjects being predominantly white males.

Page 20: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Confirmation

Employees who scored 10 or greater on the Sleepiness Scale were offered the opportunity to wear a device to identify the presence of Obstructive Sleep Apnea

The unit was shipped and worn for one night

The unit was then shipped back to US for data interpretation

Page 21: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Confirmation Results

20 tests completed

18 confirmed positive for OSA

All participants scoring 11 or higher on screening

tested positive for sleep apnea

Page 22: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Confirmation Data

Page 23: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

AHI vs BMI

Page 24: Railroad Worker Excessive Daytime Sleepiness Study Benjamin Gerson M.D. University Services Philadelphia, PA 19154 benjamin@uservices.com.

Sleepiness Score vs BMI