RACING MEDICATION AND TESTING CONSORTIUM Dan Fick The Jockey Club Executive Director & Executive Vice President.

RACING MEDICATION RACING MEDICATION AND TESTING AND TESTING CONSORTIUMCONSORTIUM

Dan FickDan FickThe Jockey ClubThe Jockey ClubExecutive Director Executive Director & Executive Vice President& Executive Vice President

TopicsTopics

1.1. MissionMission

2.2. Uniform Model RulesUniform Model Rules

3.3. ResearchResearch

4.4. Anabolic SteroidsAnabolic Steroids

5.5. Drug TestingDrug Testing

6.6. FundingFunding

Mission of RMTCMission of RMTC

To develop, promote and coordinate, at To develop, promote and coordinate, at the national level, policies, research and the national level, policies, research and educational programs that seek to:educational programs that seek to:– ensure fairness and integrity of racingensure fairness and integrity of racing– ensure the health and welfare of ensure the health and welfare of

racehorses and participants racehorses and participants – protect the interests of the racing protect the interests of the racing

publicpublic

RMTC was formed in 2002 as a 501 (c)(3) RMTC was formed in 2002 as a 501 (c)(3) charitable organization; donations are charitable organization; donations are tax deductibletax deductible..

Board of DirectorsBoard of Directors AAEPAAEP AQHAAQHA Arabian Jockey ClubArabian Jockey Club Breeders’ CupBreeders’ Cup California TB TrainersCalifornia TB Trainers Churchill Downs Churchill Downs Del Mar Del Mar Hambletonian SocietyHambletonian Society Harness Tracks of Harness Tracks of

AmericaAmerica Jockey Club      Jockey Club      Jockeys’ GuildJockeys’ Guild KeenelandKeeneland Kentucky TB Kentucky TB

AssociationAssociation

Magna Magna EntertainmentEntertainment

National HBPA National HBPA NTRANTRA NYRANYRA Oak TreeOak Tree RCIRCI THATHA TOBATOBA TB Owners of TB Owners of

CaliforniaCalifornia TRATRA TRPBTRPB USTAUSTA

RMTC OfficersRMTC Officers

Executive Director: Dr. Scot WatermanExecutive Director: Dr. Scot Waterman Chairman: Dr. Bobby Lewis - AAEPChairman: Dr. Bobby Lewis - AAEP Vice Chairman: Chris Scherf - TRAVice Chairman: Chris Scherf - TRA Vice Chairman: Alan Foreman - THAVice Chairman: Alan Foreman - THA Secretary: Dr. Rick Arthur - CHRBSecretary: Dr. Rick Arthur - CHRB Treasurer: Tom Charters - Treasurer: Tom Charters -

Hambletonian Hambletonian CEO: Dan Fick - The Jockey ClubCEO: Dan Fick - The Jockey Club

RMTC Model of RMTC Model of OperationOperation Goals:Goals:

– Uniform regulationUniform regulation– Level playing fieldLevel playing field– Welfare and safety of participantsWelfare and safety of participants

Implementation Strategy:Implementation Strategy:– Review existing researchReview existing research– New researchNew research– Scientific Advisory CommitteeScientific Advisory Committee– Consensus of directorsConsensus of directors

Model Rules Phase 1 Model Rules Phase 1 (2005)(2005) Veterinary PracticesVeterinary Practices Prohibited PracticesProhibited Practices Drug Classifications/Categorization Drug Classifications/Categorization Permitted Therapeutics:Permitted Therapeutics:

– Race DayRace Day Voluntary use of LasixVoluntary use of Lasix Adjuncts permitted pending researchAdjuncts permitted pending research Anti-ulcer medicationsAnti-ulcer medications

– One of three NSAID – Bute, Banamine One of three NSAID – Bute, Banamine & Ketoprofen – 24 hours& Ketoprofen – 24 hours

Language adopted

Language in the process of being adopted

Process require significant legislative action

Process has not been started

No horse racing or harness racing commission

Model Rules

Uniform Penalties Uniform Penalties (2006)(2006) Three-tiered grid system simplified Three-tiered grid system simplified

existing RCI penaltiesexisting RCI penalties Significantly increases penalties for Significantly increases penalties for

illegal and prohibited performance-illegal and prohibited performance-enhancing drugs enhancing drugs

Reduces penalties for therapeutic Reduces penalties for therapeutic medication mistakesmedication mistakes

Redefines trainer responsibilityRedefines trainer responsibility– Mitigating and aggravating circumstances Mitigating and aggravating circumstances

“checklist” for stewards“checklist” for stewards– Added penalties for other culpable licensees: Added penalties for other culpable licensees:

veterinarians, owners and groomsveterinarians, owners and grooms Adopted as rule or policy in 25 statesAdopted as rule or policy in 25 states

Uniform ModelUniform Model Penalties Policy Penalties Policy Class AClass A – Illegal, not approved, significant – Illegal, not approved, significant

performance enhancement performance enhancementLifetime: Lifetime: – 11stst Offense – Offense – MinimumMinimum 1 year & $ 10,000 1 year & $ 10,000

Maximum Maximum 3 year & $ 25,0003 year & $ 25,000

– 33rdrd Offense – Offense – MinimumMinimum 5 year & $ 50,000 5 year & $ 50,000 Maximum 10 year & Maximum 10 year &

$100,000$100,000

Class CClass C – Therapeutic medications at less than – Therapeutic medications at less than performance enhancing performance enhancing levelslevels365 Days365 Days– 11stst Offense – Offense – Minimum Minimum $ 500 $ 500 – 22ndnd Offense – Offense – Minimum Minimum 15 day & $ 1,000 15 day & $ 1,000

– 33rdrd Offense – Offense – Minimum Minimum 30 day & $ 2,500 30 day & $ 2,500

Regulation of anabolic steroidsRegulation of anabolic steroids– Limited to four FDA-permitted Limited to four FDA-permitted

anabolicsanabolics Stanozolol (Winstrol) Stanozolol (Winstrol) Boldenone (Equipoise)Boldenone (Equipoise) Nandrolone Nandrolone TestosteroneTestosterone

– 30-45 days withdrawal time30-45 days withdrawal time Out-of-competition testingOut-of-competition testing

– Blood-doping agents – EPO & Blood-doping agents – EPO & DarbypoietinDarbypoietin

– Illegal & prohibited drugsIllegal & prohibited drugs

New RCI Model Rules

ResearchResearch

Research grants - $965,000 to dateResearch grants - $965,000 to date– Performance enhancersPerformance enhancers

Erythropoietin, Ethanol and Cone Snail VenomErythropoietin, Ethanol and Cone Snail Venom

– TherapeuticsTherapeutics Procaine Penicillin, Flunixin, Clenbuterol and Amicar Procaine Penicillin, Flunixin, Clenbuterol and Amicar

– Environmental contaminants Environmental contaminants Morphine and CocaineMorphine and Cocaine

– Research on 50 therapeutics and anabolic Research on 50 therapeutics and anabolic steroidssteroids

– Unknowns from backstretch contactsUnknowns from backstretch contacts 25-horse research training stable 25-horse research training stable Dr. Don Catlin – Anti-Doping Research LabDr. Don Catlin – Anti-Doping Research Lab

RMTC Research RMTC Research ProgramProgram RMTC is also focused on developing tests RMTC is also focused on developing tests

for “designer” drugsfor “designer” drugs ““Unknown” acquisition and analysis:Unknown” acquisition and analysis:

– RMTC works with sources and purchases RMTC works with sources and purchases products being marketed as “performance products being marketed as “performance enhancing”enhancing”

– Over a dozen vials and syringes have been Over a dozen vials and syringes have been analyzed over the past two yearsanalyzed over the past two years

– Majority contain “voodoo” products and are of Majority contain “voodoo” products and are of little concern little concern

– In 2007, one unknown led to a federal In 2007, one unknown led to a federal investigation and prosecution of a “race-day investigation and prosecution of a “race-day medication” websitemedication” website

Withdrawal Times Withdrawal Times ResearchResearch Identified drugs with legitimate uses Identified drugs with legitimate uses Prioritized drugs into five groupsPrioritized drugs into five groups Collected previous science on each drugCollected previous science on each drug If science is insufficient then perform If science is insufficient then perform

administrations on a minimum of 20 horsesadministrations on a minimum of 20 horses Research costs of administration, Research costs of administration,

collection and analysis are $20,000 up to collection and analysis are $20,000 up to $40,000 depending on drug $40,000 depending on drug

Plasma is preferred but some drugs will Plasma is preferred but some drugs will have both urine and plasma collectedhave both urine and plasma collected

Ultimate goal: uniform withdrawal time Ultimate goal: uniform withdrawal time with a corresponding threshold level of with a corresponding threshold level of drug which regulates the withdrawal timedrug which regulates the withdrawal time

Withdrawal Times Withdrawal Times ResearchResearch Priority Group Priority Group

11– AcepromazineAcepromazine– ButorphanolButorphanol– DetomidineDetomidine– GlycopyrrolateGlycopyrrolate– LidocaineLidocaine– MepivacaineMepivacaine– MethocarbamolMethocarbamol– PyrilaminePyrilamine

Priority Group Priority Group 22– BoldenoneBoldenone– DantroleneDantrolene– DexamethasoneDexamethasone– FluphenazineFluphenazine– HydroxyzineHydroxyzine– NandroloneNandrolone– StanozololStanozolol– TestosteroneTestosterone

Withdrawal Times Withdrawal Times ResearchResearch Priority Group 3Priority Group 3

– AlbuterolAlbuterol– BetamethasoneBetamethasone– DiclofenacDiclofenac– MethylprednisoloMethylprednisolo

nene– ReserpineReserpine– TriamcinoloneTriamcinolone– TrichlormethiazidTrichlormethiazid

ee– XylazineXylazine

Priority Group 4Priority Group 4– AtropineAtropine– Beclomethasone Beclomethasone – BuscopanBuscopan– CromolynCromolyn– IsoxsuprineIsoxsuprine– PentoxyfyllinePentoxyfylline– PhenytoinPhenytoin– PrednisolonePrednisolone

Withdrawal Times Withdrawal Times ResearchResearch Priority Group 5Priority Group 5

– DiazepamDiazepam– DipyroneDipyrone– FluorprednisolFluorprednisol

oneone– GuaifenesinGuaifenesin– IsoflupredoneIsoflupredone– PrednisonePrednisone

Research finishedResearch finished– Aminocaproic AcidAminocaproic Acid– CarbazochromeCarbazochrome– ClenbuterolClenbuterol– Procaine PenicillinProcaine Penicillin– CimetidineCimetidine– DMSODMSO– FlunixinFlunixin– FurosemideFurosemide– KetoprofenKetoprofen– OmeprazoleOmeprazole– PhenylbutazonePhenylbutazone– RanitidineRanitidine

Withdrawal Time Withdrawal Time DatabaseDatabase Withdrawal times posted for 18 Withdrawal times posted for 18

jurisdictions and over 70 drugsjurisdictions and over 70 drugs Database is searchable by drug Database is searchable by drug

and by jurisdictionand by jurisdiction Over 2,000 unique users in first Over 2,000 unique users in first

month of availabilitymonth of availability Help us add more (New Mexico)Help us add more (New Mexico) www.rmtcnet.comwww.rmtcnet.com, click on , click on

“Withdrawal Times” tab at top of page“Withdrawal Times” tab at top of page

Scot

Waterman

Anabolic steroids Anabolic steroids

Why now?Why now?– Several surveys showed extremely Several surveys showed extremely

high levels of usehigh levels of use– Perception and level of public Perception and level of public

consciousness of anabolic steroids consciousness of anabolic steroids – Federal scrutiny of major league Federal scrutiny of major league

sportssports– Legislation to ban steroids Legislation to ban steroids

introduced in Congressintroduced in Congress– Harmonizes the U.S. Harmonizes the U.S.

internationallyinternationally

Anabolic steroids Anabolic steroids

Model rule approved by RCI in April Model rule approved by RCI in April 20072007

Revised by RCI in December 2007 Revised by RCI in December 2007 to cover the intact maleto cover the intact male

Model rule contains urinary Model rule contains urinary thresholds for 4 anabolic steroids thresholds for 4 anabolic steroids that are permitted by FDAthat are permitted by FDA

Plasma thresholds will be added Plasma thresholds will be added once administration studies are once administration studies are completed this fallcompleted this fall

Anabolic Steroids Anabolic Steroids

AR, AZ, CO, DE, IA, IL, IN, PA, VA, WA AR, AZ, CO, DE, IA, IL, IN, PA, VA, WA have adopted this model rulehave adopted this model rule

At least 12 other states have started At least 12 other states have started the adoption processthe adoption process

RMTC & RCI have encouraged every RMTC & RCI have encouraged every state to be done with the adoption state to be done with the adoption process by 12/31process by 12/31

Recommendations for implementation Recommendations for implementation approved by RMTC & RCI in March approved by RMTC & RCI in March 20082008

Anabolic Steroids Anabolic Steroids

RMTC Board recommends:RMTC Board recommends:– 90-day grace period on penalty 90-day grace period on penalty

enforcement when rule is introducedenforcement when rule is introduced– Notification to owner/trainer for Notification to owner/trainer for

overage,overage,– No fine or loss of purse absent No fine or loss of purse absent

aggravating circumstancesaggravating circumstances– After 90 days, jurisdictions should After 90 days, jurisdictions should

follow the penalty guidelines in the follow the penalty guidelines in the model rules $500 and loss of purse for model rules $500 and loss of purse for 11stst violation violation

– Pre-entry testing must be made Pre-entry testing must be made available in some formavailable in some form

Anabolic Steroids Anabolic Steroids

RMTC Board recommends:RMTC Board recommends:– Boldenone, stanozolol, nandrolone and Boldenone, stanozolol, nandrolone and

testosterone should not be administered testosterone should not be administered within 30 days of a racewithin 30 days of a race

– If needed outside of 30 days, must be If needed outside of 30 days, must be documented by veterinarian, must include documented by veterinarian, must include diagnosis and filed with the regulatory diagnosis and filed with the regulatory bodybody

– Horse should then test negative before Horse should then test negative before being allowed to enter.being allowed to enter.

– Claimed horses may be tested on request Claimed horses may be tested on request and at the cost of the claimant. If and at the cost of the claimant. If positive, claim can be voided and cost of positive, claim can be voided and cost of testing borne by original owner.testing borne by original owner.

Anabolic Steroids Anabolic Steroids

Significant interest at the federal level Significant interest at the federal level on this issue on this issue

Reps from RMTC, RCI, NTRA met with Reps from RMTC, RCI, NTRA met with congressional staffers in Jan ‘08congressional staffers in Jan ‘08

Alex Waldrop recently testified in front Alex Waldrop recently testified in front of House Energy and Commerce Sub-of House Energy and Commerce Sub-committeecommittee

Interstate Horseracing Act is in play, Interstate Horseracing Act is in play, state regulation of drug control also in state regulation of drug control also in jeopardyjeopardy

Congressmen Whitfield & Rush drafting Congressmen Whitfield & Rush drafting legislation with possible hearing in mid-legislation with possible hearing in mid-June.June.

Drug Testing Drug Testing ObjectivesObjectives

Uniform TestingUniform Testing– Standards for chain of custody, split and frozen Standards for chain of custody, split and frozen

samplessamples– Standard operating procedures and testing Standard operating procedures and testing

protocols protocols – Quality assurance and blind samplingQuality assurance and blind sampling– Laboratory accreditationLaboratory accreditation

Future ConsiderationsFuture Considerations– National industry-owned reference laboratoryNational industry-owned reference laboratory– Potential for consolidation of 18 existing drug-Potential for consolidation of 18 existing drug-

testing laboratoriestesting laboratories

FundingFunding

$2.7 million bridge financing from industry $2.7 million bridge financing from industry organizations 2003-2006organizations 2003-2006

2007 Contributions = $683,1262007 Contributions = $683,126

2008 Projected Funding:2008 Projected Funding:– $1 per start from horsemen and racetracks$1 per start from horsemen and racetracks– $700,000 from industry organizations$700,000 from industry organizations– $500,000 research and testing grants from$500,000 research and testing grants from

The Jockey Club & Kentucky Horse Racing AuthorityThe Jockey Club & Kentucky Horse Racing Authority– Tax-deductible donations from individualsTax-deductible donations from individuals

RMTC: Contact UsRMTC: Contact Us

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