PULSE October 28, 2009 Pennsylvania State College of Medicine Nicolai Wohns
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PULSEOctober 28, 2009
Pennsylvania State College of MedicineNicolai Wohns
Hyperthyroidismalso Hypothyroidism
Thyroid Function?
Thyroid: Θυροειδής
Shield: θυρεός
Metabolism
Growth
Development
Hyperthyroidism:
Common symptoms and signs
Heat intolerance
Weight loss (with increased appetite)
Easily fatigued (but with insomnia)
Trembling hands
Hard, irregular heartbeat (palpitations)
Irritable, nervousness
Severe casesShortness of breath
Chest pain
Muscle weakness
Causes?
Grave’s Disease
Grave’s Disease:
Common symptoms and signs
Fatigue
Weight loss with increased appetite
other symptoms of hyperthyroidism
Exophthalmos
Non-pitting edema
Exophthalmos / Proptosis
Non-pitting Edema
Causes?
Pretibial Myxedema
Another autoimmune disorder…
Hashimoto’s thyroiditis
Hyperthyroidism vs Hypothyroidism
Hashimoto’s?
Hypothyroidism:
Common symptoms and signs
Heat intolerance
Weight loss (with increased appetite)
Easily fatigued (but with insomnia)
Trembling hands
Hard, irregular heartbeat (palpitations)
Irritable, nervousness
Sensitivity to cold
Weight gain
Fatigue
Goiter
Bradycardia, Tachycardia
Depression, mania, panic attacks
Hyperthyroidism
Treatment
Treatment:Grave’s Disease
Antithyroid drugs
Radioiodine:
radioactive iodine-131
Surgery: thyroidecto
my
Treatment:Hashimoto’s Disease
T4 supplementation• synthetic L-T4; standard treatment
T4 and T3 in combination
• both synthetic L-T4 and L-T3 simultaneously
Desiccated Thyroid Extract
• Pig thyroid extract: natural forms of L-T4 and L-T3
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