1 Pulmonary Center Newsletter: June 2019-September 2019 ello and Welcome back! We have had a very eventful summer! As the fall begins to roll in, let’s look back on some of the accomplishments and events from June 2019-September 2019. Let’s also look ahead to the upcoming events for winter and spring! Table of Contents: H New Faces ….…….…………………………………….....….2 2019 Summer Events…....……….……………………….3 Awards & Accomplishments…….…....……….………8 Upcoming Events……...………………………………....11 Pulmonary Alumni: Where are they now?.......12 Publications………………………….………..……...….…14
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Pulmonary Center Newsletter:
June 2019-September 2019
ello and Welcome back! We have had a very eventful summer! As the fall
begins to roll in, let’s look back on some of the accomplishments and events from
June 2019-September 2019. Let’s also look ahead to the upcoming events for winter
and spring!
Table of Contents:
H
New Faces ….…….…………………………………….....….2
2019 Summer Events…....……….……………………….3
Awards & Accomplishments…….…....……….………8
Upcoming Events……...………………………………....11
Pulmonary Alumni: Where are they now?.......12
Publications………………………….………..……...….…14
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New Faces:
Theodore Lee Allergy Fellow
Lindsey Stein Administrative Assistant
New Pulmonary & Critical Care Fellows:
Caitlin Butler Erin Crossey Ariella Krones
Shelsey Johnson Mallory LeSieur Nathan Mesfin
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2019 Summer Events
A look back on some of the fun events from this quarter including, past Work in
Progress Seminar, The 2019 Sue Kim Hanson Lecture, the new Pulmonary CCR
Conference and more!
Work in Progress:
The Last Season!!
Carolina Lyon De Ana Elim Na Ph.D. Students June 21st
Tien Peng Asst. Prof. of Medicine
University of California San Francisco June 14th
Alan Fine
Prof. of Medicine
July 26th
Konstantinos Alysandratos
Asst. Prof. of Medicine
June 28th
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Zea Borok, Guest Lecture:
Zea Borok, M.D. USC Professor of Medicine, Keck School of Medicine Ralph Edington Chair in Medicine, Chief, Division of Pulmonary and Critical Care Medicine “Claudin 18 is a novel regulator of lung epithelial stem/progenitor cell homeostasis, YAP signaling and tumorigenesis”
September 6th, 2019
Evans Day
October 3rd
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Aquarium Outing
The Pulmonary Center enjoyed a fun
day in the sun with friends and family
at the New England Aquarium on
September 21st!
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2019 Sue Kim Hanson
Lecture in Immunology:
Every year, The BUSM community convenes to
celebrate the life of Sue Kim Hanson, an
extraordinary BU Ph.D. student who died tragically
with her husband and daughter on September 11,
2001.
Sue was born in Los Angeles, California. She spent
her early childhood in Korea, returning to Los
Angeles at age 6. In 1989 she received a B.A. degree
in biology and psychology from the University of
California, Berkley. After graduation she worked for
Cetus Corporation and was involved with early development of gene amplification by polymerase chain
reaction. She moved to Boston and earned a M.A. in medical sciences from Boston University School of
Medicine in 1992. After graduation, she joined the laboratory of Dr. Hardy Kornfeld in the Pulmonary
Center at BUSM. While in the Kornfeld laboratory, she concurrently entered the Ph.D. program in the
Department of Pathology and Laboratory Medicine (immunology track) at BUSM. Sue’s thesis project
was an investigation of the role of interleukin-16 in immunity.
On September 11, 2001, Sue was traveling to Los Angeles with her husband, Peter Hanson (BU School of
Management ’94) and their two-year-old daughter, Christine Lee, on United Airlines flight 175, the
second plane that struck the World Trade Center. Sue was scheduled to defend her dissertation in
November of 2001. Her degree was awarded posthumously by unanimous vote of her thesis committee.
This year’s Sue Kim Hanson Lecture was delivered by:
Anne Sperling, Ph.D. Professor of Medicine University of Chicago School of Medicine “From Mice to Humans: Studies on Asthma” September 27th, 2019
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Pulmonary Combined Clinical and
Research (CCR) Conference
This year, we are starting something new, a
Combined Clinical and Research (CCR)
Conference. The CCR Conference unifies two
efforts which were previously distinct. In
Pulmonary Grand Rounds, physicians
present cases and discuss cutting-edge
clinical approaches to medical challenges. In
Work-in-Progress Seminars, scientists
present research questions, experiments,
results, and interpretations, discussing
implications for advancing biology and
Faculty Leaders for the 2019-2020 CCR Conference medicine. The Pulmonary CCR Conference
includes both of these activities in one
extended session. As often as possible, the 2
components are coordinated so that the
medical cases and the research questions
are directly and immediately mutually
informative. All Pulmonary Center members
(faculty, trainees, and staff, from all
disciplines) participate in both components.
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Awards and Accomplishments
Yang Jin
Associate Professor of Medicine
New NHLBI R01
“LncRNA regulates lung inflammation”
Asked to serve on the Lung Cellular, Molecular, and Immunobiology Study
Section, Center for Scientific Review, for the National Institutes of Health
Kari Gillmeyer
Pulmonary Fellow
New NHLBI F32
“Determining disparities in treatment of pulmonary arterial hypertension
nationally.”
Adeline Matschulat
Ph.D. Student
ew NHLBI F31
“Defining molecular signals that influence airway basal cell renewal and
growth.”
Nicholas Bosch
Pulmonary Fellow
New NIGMS F32
“Normalizing vasopressor dose to standardize vasopressors practice in septic
Assistant Professor of Medicine New AAAAI Foundation Faculty Development Award “How B cell developmental defects shape manifestations of common variable immunodeficiency. “
Markus Bosmann
Associate Professor of Medicine Promoted to the position of Associate Professor
Lee Quinton
Associate Professor of Medicine and Pathology Asked to serve on the Lung Cellular, Molecular, and Immunobiology Study Section, Center for Scientific Review, for the National Institutes of Health.
Yang Jin
Associate Professor of Medicine
Asked to serve on the Lung Cellular, Molecular, and Immunobiology Study
Section, Center for Scientific Review, for the National Institutes of Health
Eric Abston
Pulmonary Fellow
New Chest Foundation Grant “Noninvasive Quantification of Pulmonary Fibrosis Due to Radiation Induced Lung Injury Using [68Ga]CBP8 Type 1 Collagen Probe”
Received the Evans Junior Faculty Research Merit Award
Kristine abo
M.D./Ph.D. Student
Received First Place Basic Poster Presentation Award at Evans Day
“Pluripotent stem cell-based modeling of cigarette smoke injury to the
human alveolar epithelium.”
Anukul Shenoy
Postdoctoral Fellow
Received Second Place Basic Poster Presentation Award at Evans Day
“Lung epithelial cells exhibit anatomically segregated and temporally
dynamic abilities to interact with CD4+ T cells.”
Seppo Rinne
Assistant Professor of Medicine
New American Medical Association Grant
“Physician Experience with EHR Transformation.”
Hasmeena Kathuria
Assistant Professor of Medicine
Received the Evans Clinician Designation from the Department of
Medicine for outstanding clinical skills, attitude and professionalism
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Upcoming Events
2019 Jerome S. Brody, MD, Lectureship:
GR Scott Budinger, M.D. Northwester Medicine, Feinberg School of Medicine Chief of Pulmonary and Critical Care in the Department of Medicine Ernest S. Bazley Professor of Airway Diseases Professor of Medicine (pulmonary and Critical Care) and cell and Developmental Biology January 22nd, 2020
2019 Gordon L. Snider, MD, Memorial
Lecture:
Naftali Kaminski, M.D. Yale School of Medicine Boehringer Ingelheim Pharmaceuticals, Inc. Professor of Medicine (Pulmonary) Section Chief, Pulmonary, Critical Care & Sleep Medicine April 1st, 2020
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We thank our alumni who shared some of their recent
accomplishments including:
Antoine Guillon Associate Professor, Critical care Section Tours University, France Research Center for Respiratory Diseases INSERM UMR 1100, France Received a grant from the H2020 Horizon 2020 is the EU funding program for research and innovation and it provides funding for multi-national collaboration projects.
“We built the FAIR project across 7 countries and 14 research institutes. It aims at evaluating an alternative adjunct strategy to standard of care antibiotics for treating pneumonia caused by antibiotic-resistant bacteria: activation of the innate immune system in the airways. I lead one of the 8 work-packages (the first-in-man trial) and I am involve in another WP (pre-clinical animal model). We received 10.000 k.euro for the whole consortium and for a 5-year period.”
-Antoine
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We also received news about the following publications from
our extended Pulmonary Center family:
Hassan A. Chami,Hussain Isma’eel,Hani Tamim,Marwa Adawi,Mariam Al Kuwari,Ahmad Al
Mullah. The Association of Water-Pipe Smoking and Coronary Artery Calcium in a Community-
Based Sample. Chest. 2019 Jun;155(6):1217-1225. doi: 10.1016/j.chest.2019.01.010. Epub 2019
Jan 23. PMID: 30684475
Guillon A, Pardessus J, Lhommet P, Parent C, Respaud R, Marchand D, Montharu J, De Monte
M, Janiak P, Boixel C, Audat H, Huille S, Guillot E, Heuze-Vourc'h N. Exploring the fate of
inhaled monoclonal antibody in the lung parenchyma by microdialysis. MAbs. 2019 Mar
Guillon A, Preau S, Aboab J, Azabou E, Jung B, Silva S, Textoris J, Uhel F, Vodovar D, Zafrani
L, de Prost N, Radermacher P; Preclinical septic shock research: why we need an animal ICU.
Translational Research Committee of the French Intensive Care Society (Société de Réanimation
de Langue Française). Ann Intensive Care. 2019 Jun
Morello E, Pérez-Berezo T, Boisseau C, Baranek T, Guillon A, Bréa D, Lanotte P, Carpena X,
Pietrancosta N, Hervé V, Ramphal R, Cenac N, Si-Tahar M. Pseudomonas aeruginosa
Lipoxygenase LoxA Contributes to Lung Infection by Altering the Host Immune Lipid
Signaling. Front Microbiol. 2019 Aug
Kumar NP, Moideen K, Nancy A, Viswanathan V, Shruthi BS, Sivakumar S, Natarajan M,
Kornfeld H, Babu S. Heterogeneity in the cytokine profile of tuberculosis - diabetes co-
morbidity. Cytokine. 2019 Aug 28;125:154824. doi: 10.1016/j.cyto.2019.154824. [Epub ahead
of print] PMID: 31472402
Martinez N, Cheng CY, Ketheesan N, Cullen A, Tang Y, Lum J, West K, Poidinger M, Guertin
DA, Singhal A, Kornfeld H. mTORC2/Akt activation in adipocytes is required for adipose
tissue inflammation in tuberculosis. EBioMedicine. 2019 Jul;45:314-327. doi: