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Post-traumatic stress disorder (PTSD): the treatment of PTSD in adults and children Understanding NICE guidance – information for people with PTSD, their advocates and carers, and the public March 2005 Information about NICE Clinical Guideline 26
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Page 1: PTSD 2 NHS

Post-traumatic stress disorder(PTSD): the treatment of PTSD in adults and children

Understanding NICE guidance – information forpeople with PTSD, their advocates and carers, and the public

March 2005

Information about NICE Clinical Guideline 26

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National Institute for Clinical Excellence

MidCity Place71 High HolbornLondonWC1V 6NA

www.nice.org.uk

ISBN: 1-84257-915-0

Published by the National Institute for Clinical ExcellenceMarch 2005Artwork by LIMA Graphics Ltd, Frimley, SurreyPrinted by Abba Litho Sales Limited, London

© National Institute for Clinical Excellence, March 2005. All rights reserved. This material may be freely reproduced for educational andnot-for-profit purposes within the NHS. No reproduction by or forcommercial organisations is allowed without the express writtenpermission of the National Institute for Clinical Excellence.

Post-traumatic stress disorder (PTSD): the treatment of PTSD inadults and childrenUnderstanding NICE guidance – information for people with PTSD,their advocates and carers, and the public

Issue date: March 2005

To order copiesCopies of this booklet can be ordered from the NHS Response Line—telephone 0870 1555 455 and quote reference number N0849. Aversion in English and Welsh is also available, reference number N0850.Mae fersiwn yn Gymraeg ac yn Saesneg ar gael hefyd, rhif cyfeirnodN0850. The English and bilingual versions of this booklet are alsoavailable from the NICE website (www.nice.org.uk/CG026publicinfo).The NICE clinical guideline on which this information is based, ‘Post-traumatic stress disorder (PTSD): the management of PTSD in adultsand children in primary and secondary care’, is available from the NICEwebsite (www.nice.org.uk/CG026NICEguideline). A quick referenceguide for healthcare professionals is also available from the website(www.nice.org.uk/CG026quickrefguide), and the NHS Response Line(reference number N0848).

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Contents

About this information 3Clinical guidelines 4What the recommendations cover 5How guidelines are used in the NHS 6

What is PTSD? 7Where can I find help and treatment? 10What treatments are available for PTSD? 13

Will I be offered psychological treatment? 14Will I be offered medication? 20I have other illnesses or problems besides PTSD. Will this affect my treatment for PTSD? 27Will my treatment be affected if I am seeking compensation? 28Will I be offered any other kind of help by healthcare professionals? 28

What treatments are available for young people? 29Information for families and carers 31

How can I support a family member with PTSD? 31How can I find support for myself? 31

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Where you can find more information 33If you want to read the other versions of this guideline 33If you want more information about PTSD 34If you want to know about related 35NICE guidance

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Understanding NICE guidance – Post-traumatic stress disorder 3

About this information

This information describes the guidance that the National Institute for Clinical Excellence(called NICE for short) has issued to the NHS on the treatment and care of people with post-traumatic stress disorder (PTSD). It is basedon ‘Post-traumatic stress disorder (PTSD): themanagement of PTSD in adults and children inprimary and secondary care’, which is a clinicalguideline produced by NICE for doctors, nursesand others working in the NHS in England andWales. Although this information has beenwritten mainly for people with PTSD, it may also be useful for family members, those who care for people with PTSD and anyoneinterested in PTSD or in healthcare in general.

In this document the term ‘PTSD sufferer’ is used to describe someone with PTSD. This termwas chosen on the basis of a survey conductedby members of the group who wrote the NICEguideline and who have PTSD, although it isrecognised that some people with PTSD may use alternative terms.

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Clinical guidelines

Clinical guidelines are recommendations forgood practice. The recommendations in NICEguidelines are prepared by groups of healthworkers, people representing the views of those who have or care for someone with thecondition, and scientists. The groups look at the evidence available on the best way oftreating or managing the condition and makerecommendations based on this evidence.

There is more about NICE and the way that the NICE guidelines are developed on the NICEwebsite (www.nice.org.uk). You can downloadthe booklet ‘The guideline development process– an overview for stakeholders, the public andthe NHS’ from the website, or you can order acopy by phoning the NHS Response Line on 0870 1555 455 (quote reference number N0472).

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What the recommendations cover

NICE clinical guidelines can look at differentareas of diagnosis, treatment, care, self-help or acombination of these. The areas that a guidelinecovers depend on the topic. They are laid out ina document called the scope at the start ofguideline development.

The recommendations in ‘Post-traumatic stressdisorder (PTSD): the management of PTSD inadults and children in primary and secondarycare’, which are also described here, cover:

• the care you can expect to receive from yourGP or other healthcare professional

• the information you can expect to receiveabout your condition and its treatment

• what treatment you can expect, which mayinclude psychological therapies and drugtreatment

• the services that may help you with PTSD,including specialist mental health services.

If you have questions about the specific treatmentsand options covered, talk to your doctor or nurse(or another healthcare professional, depending onwhat it is you want to know).

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How guidelines are used in the NHS

In general, healthcare workers in the NHS areexpected to follow NICE’s clinical guidelines. Butthere will be times when the recommendationswon’t be suitable for someone because of his orher specific medical condition, general health,wishes, or a combination of these. If you thinkthat the treatment or care you receive does notmatch the treatment or care described on thepages that follow, you should talk to yourdoctor, nurse or other healthcare professionalinvolved in your treatment.

You have the right to be fully informed and toshare in making decisions about your healthcare,and the care you receive should take account ofyour individual needs.

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What is PTSD?

Post-traumatic stress disorder (or PTSD for short)is the name given to the psychological andphysical problems that can sometimes followparticular threatening or distressing events.These events might include:

• a major disaster

• war

• rape or sexual, physical or emotional abuse

• witnessing a violent death

• a serious accident

• traumatic childbirth

• other situations in which a person was veryafraid, horrified, helpless, or felt that his orher life was in danger.

The trauma can be a single event or a series ofevents taking place over many months or evenyears.

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PTSD may affect the person directly involved in atraumatic event or situation. It may also developin members of the emergency services or infamilies of those involved in a traumatic event.PTSD is quite common—up to a third of peoplewho have experienced a traumatic event may goon to develop PTSD and it may affect about 8%1

of people at some point in their lives. It candevelop in people of any age, including children.

One of the most common symptoms of PTSD ishaving repeated and intrusive distressing memoriesof the event. There may also be a feeling ofreliving (or ‘re-experiencing’) the event through‘flashbacks’ or nightmares, which can be verydistressing and disorientating. There can also bephysical reactions, such as shaking and sweating.

Because the memory can be very intense andupsetting, some PTSD sufferers may avoid peopleor situations that remind them of the trauma, or try to ignore the memories and avoid talkingabout the event. Some people may also forgetsignificant parts of the traumatic event. Otherpeople will think about the event constantly, whichstops them coming to terms with it (they may, forinstance, ask themselves why the event happenedto them or how it could have been prevented).

1 This figure is based on studies in adult patients in the USA andAustralia.

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PTSD sufferers may have emotions or feelingsthat are difficult to deal with, such as guilt orshame, or they may feel that they do notdeserve help. They may also feel anxious orirritable, and find it difficult to concentrate andsleep. For some people it can mean that doingordinary things like going to work or school orgoing out with friends becomes very difficult.

It is not uncommon to have upsetting andconfusing feelings and to experience verydistressing symptoms in the first few weeks aftera traumatic event. Sometimes these feelings passafter a few weeks or so, but if they persist formore than a month after the event, a personmay have PTSD.

Some people, however, may not have animmediate reaction to a distressing event andmay develop PTSD months or even years afterthe event.

It is thought that about 80–90% of PTSDsufferers also have other problems, such asdepression (which is quite common) and anxietydisorders. Some people start to use recreationaldrugs or alcohol as a way to cope, especially ifthey have had PTSD or experienced trauma for a long time.

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Where can I find help andtreatment?

If you have experienced a trauma and havedistressing symptoms, your GP is the best placeto start. He or she should be aware of the typesof trauma associated with the development ofPTSD. When you first go to see your GP, he orshe will want to find out about your generalhealth, how you are feeling, and how life is athome, school or work.

If you see your GP about distressing symptoms in the first 4 weeks after a traumatic event, you may be told it is very common to feel likethis and not to be alarmed. You may not beoffered any treatment at this stage, althoughyour GP should offer you another appointmentwithin 1 month. (If you do not have a furtherappointment you should go back to your doctorif you do not feel better.) However, if yoursymptoms are severe, your GP should offer you treatment straight away.

If you are a refugee or asylum seeker, you maybe asked questions during your initial healthassessment to determine if you have symptomsof PTSD. This is because refugees and asylumseekers have often experienced a major traumaand may be at risk of developing PTSD.

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If you are advised that you have PTSD, your GPshould give you clear information about thecommon reactions to traumatic events, howPTSD starts, the symptoms of PTSD and how itcan be treated.

If your GP thinks that you need furthertreatment, you may be referred to someone who is trained and skilled in providing treatmentfor PTSD sufferers (this may be a counsellor,community psychiatric nurse, psychologist, orpsychiatrist). You may be offered an assessmentwhere you will be asked about your physical and psychological health and your social needs,and whether you have thoughts about harming yourself.

Ideally you should receive all your treatmentfrom one healthcare professional, who should be appropriately trained in giving the treatment.(You may wish to ask what experience theyhave.) If you see more than one person aboutyour PTSD, there should be a clear writtenagreement about who is monitoring yourtreatment and care. You, and your family and carers if appropriate, should be able to see this agreement.

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All healthcare professionals should treat youwith respect, sensitivity and understanding, andexplain PTSD and its treatment to you simplyand clearly.

If your first language is not English, youshould be offered an interpreter if you needone and the healthcare professional treatingyou should be sensitive to your cultural needs.You should still be offered the same standardof care as any other patient, and told aboutall the treatments available to you.

Questions you might like to ask healthcareprofessionals about PTSD.

• Are all my problems because of PTSD?

• What treatment will I need?

• What choices do I have about mytreatment?

• How long will I need treatment for?

• Can you provide information for my family?

If you are having trouble sleeping you mayalso want to ask your healthcare professionalfor advice about this.

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What treatments areavailable for PTSD?

There are a number of treatments for PTSD that are helpful. Most involve psychologicaltreatment, but medication can also be helpfulfor adults.

Many PTSD sufferers have had the symptoms for many months and sometimes years, buttreatment can still be helpful. You should beoffered treatment regardless of when thetraumatic event happened. If you havedeveloped symptoms recently you may get better with little or no treatment.

Your healthcare professional should give you enough information about the effectivetreatments for PTSD for you to decide if youwant to have treatment or not, and whichtreatment you might prefer. Your ownpreference for a particular treatment isimportant and your healthcare professionalshould support your choice where possible.

See ‘What treatments are available for youngpeople’ on page 29 for information abouttreatment for children and young people.

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Will I be offered psychologicaltreatment?

Depending on what your symptoms are andwhen you developed PTSD, you may be offeredpsychological treatments that are specific forPTSD sufferers. These are:

• trauma-focused cognitive behavioural therapy(CBT)

or

• eye movement desensitisation andreprocessing (EMDR).

Trauma-focused CBT

This is a psychological treatment for PTSD based on cognitive behavioural therapy (CBT).CBT focuses on a person’s distressing feelings,thoughts (or ‘cognitions’) and behaviour and helps to bring about a positive change. Intrauma-focused CBT, the treatment concentratesspecifically on the memories, thoughts andfeelings that a person has about the traumatic event.

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If you are offered this treatment, yourhealthcare professional will encourage and help you to gradually recall and think about the trauma. This can be done in various waysincluding listening to recordings of your ownaccount of the trauma. You will be given help to cope with any emotional distress andbehavioural problems that may arise duringtreatment.

As the painful and traumatic memories begin todecrease, you may be encouraged and helped tostart activities that you have been avoiding sincethe trauma, such as driving a car if you haveavoided driving since an accident.

Eye movement desensitisation and reprocessing(EMDR)

This is another psychological treatment for PTSD, in which a healthcare professional willhelp you to look at your memories of the trauma(including all of the negative thoughts, feelingsand sensations experienced at the time of theevent). EMDR aims to change how you feelabout these memories and helps you to havemore positive emotions, behaviour andthoughts.

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During EMDR, you will be asked to concentrateon an image connected to the traumatic eventand the related negative emotions, sensationsand thoughts, while paying attention tosomething else, usually the therapist’s fingersmoving from side to side in front of your eyes.After each set of eye movements (about 20 seconds), you should be encouraged to let go of the memories and discuss the imagesand emotions you experienced during the eye movements. This process is repeated, thistime with a focus on any difficult, persistingmemories. Once you feel less distressed aboutthe image, you should be asked to concentrateon it while having a positive thought relating to it. It is hoped that through EMDR you canhave more positive emotions, thoughts andbehaviour in the future.

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If you have developed PTSD within 3 months ofa traumatic event you should be offered trauma-focused CBT. Depending on how you are feeling,a course of treatment is likely to be 8–12 sessionslasting for 60–90 minutes each. If your symptomsare severe, treatment may be started in the firstmonth after the trauma and may take only 4 or 5 sessions. A delay in beginning treatmentshould not affect the success of the treatment.Trauma-focused CBT should normally beprovided on an individual outpatient basis,which means that you will go to a hospital or clinic for your appointments but will not have to stay overnight.

If you have had PTSD for more than 3 monthsyou should be offered a course of trauma-focused psychological treatment (trauma-focusedCBT or EMDR). These treatments should normallybe provided on an individual outpatient basis. If you have experienced a single trauma, acourse of treatment is likely to be 8–12 sessions,usually lasting for 60–90 minutes each.

It may be necessary to have more than 12 sessions of treatment if you have experiencedthe traumatic death of a relative or friend, if thetrauma has resulted in a long-term problem ordisability, or if you have lived through a series of traumatic events.

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General information about psychologicaltreatment

Sessions should take place at regular intervals(usually at least once a week if you havedeveloped PTSD recently).

During treatment you will be asked about yourmemories of the trauma, but you may not beasked to talk about it in the first few weeks.When the trauma is discussed you may beoffered a slightly longer session (of about 90 minutes). Healthcare professionals shouldunderstand that it will be difficult and stressfulfor you to talk about the trauma, and shouldoffer support so that the treatment is not too upsetting.

If you miss an appointment your healthcareprofessional may contact you to see how you are feeling and ask why you didn’t go.

You should not usually be offered treatments on their own that have not been designed or properly tested for people who haveexperienced trauma. These include relaxationtherapy, hypnotherapy, supportive therapy, non-directive therapy, systemic psychotherapy andpsychodynamic therapy.

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Is psychological treatment suitable for everyonewith PTSD?

Psychological treatments designed for PTSDsufferers have been shown to be an effectiveway of helping most people feel better, but thisdepends on when the traumatic event occurred,when you developed PTSD, and how you arefeeling.

You should not normally be offered a singlesession of psychological therapy (often called‘debriefing’) immediately after a traumatic eventsuch as a major disaster, because research hasshown this is not very helpful and may make youfeel worse later. Instead, you should be offeredpractical support and information about how tocope over the following weeks.

What if I don’t feel better after psychologicaltreatment?

Your healthcare professional may suggest you try a different psychological treatment, or offeryou a course of medication while you are havingthe therapy.

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Questions you could ask your healthcareprofessional if you do not feel better afterpsychological treatment.

• I had expected to feel differently from howI am feeling now. Can we discuss how I amgetting on?

• Do we need to look at different types oftreatment or do we need to extend theperiod of treatment?

• Can we discuss ways to help me copebetter?

Will I be offered medication?

Medication may help to treat adults with PTSD but for most people it is not as helpful as trauma-focused psychological treatment.Healthcare professionals should usually offer you psychological treatment before medication,but you may also be offered medication if:

• you prefer not to have psychologicaltreatment, or

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• it would be very difficult for you to startpsychological treatment because of threat offurther trauma (for example, violence athome), or

• psychological treatment has not helped you.

You may be offered medication in addition topsychological treatment if the psychologicaltreatment is not helping you or if you havedepression.

See page 30 for information on the use ofmedication for children and young people.

What kind of medication can be used to treatPTSD?

The medication offered should be anantidepressant because, even if you are notsuffering from depression, this type ofmedication has been shown to help people with PTSD. There are different types ofantidepressants, but research has shown that thefollowing can be effective for PTSD sufferers:

• paroxetine (a selective serotonin reuptakeinhibitor, or SSRI)

• mirtazapine (a new kind of antidepressant)

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• amitriptyline (a tricyclic antidepressant)

• phenelzine (a monoamine oxidase inhibitor, or MAOI).

Paroxetine and mirtazapine can be prescribedfor PTSD by your GP, but generally amitriptylineand phenelzine should only be prescribed forPTSD under the supervision of a mental healthspecialist2. With phenelzine, there are somespecific cautions and advice about diet that youshould be given on an advice card when themedicine is first prescribed. You should discussthese with your doctor.

What should I know about the medication?

Before you start taking antidepressantmedication your healthcare professional should give you information about possible side effects. You should be told that when youfirst take antidepressants, particularly SSRIs,there is the possibility of symptoms such asanxiety, agitation, thoughts about suicide, andfeeling as if you can’t sit or stand still (called‘akathisia’). You should be advised to contactyour healthcare professional immediately if

2 Paroxetine is the only drug listed with a current UK product licence forPTSD at the date of publication (March 2005).

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you have any of these side effects and they aredistressing in any way.

Whichever medication you are taking, youshould be told that you may experienceunpleasant symptoms when you stop taking themedication (see page 24), miss doses or reducethe dose. These symptoms are usually mild, butcan sometimes be severe, and occur morefrequently with paroxetine than with the otherantidepressants mentioned in this booklet.

If you are prescribed an antidepressant, yourhealthcare professional should usually see you 2 weeks after starting the medication and afterthat on a regular basis (this will depend on howyou are feeling, but should usually be every2–4 weeks in the first 3 months, and then lessfrequently after that). This is to make sure thatthe medication is helping you and not causingany major side effects.

If you are aged between 18 and 29 years youshould usually be seen 1 week after starting anantidepressant and then regularly after that.Whatever your age, if you have thoughts aboutsuicide and are thought to be at risk, you shouldalso be seen after 1 week and then regularlyafter that.

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When you first start taking antidepressants(particularly SSRIs) your healthcare professionalshould ask you if you have felt very restless,anxious or agitated, and if you have hadthoughts about suicide.

How long should I take the medication?

If the medication helps, you should beencouraged to continue with the treatment for at least 12 months. After this period of time the medication can be gradually reducedover 4 weeks and then stopped (for some peopleit may take longer). You may have a few mildsymptoms when stopping the medication. If thishappens, your healthcare professional shouldreassure you that this is common and check that your symptoms are not getting worse.

If you experience severe symptoms whilereducing your medication, your healthcareprofessional may suggest you go back to theoriginal dose, or offer another kind of similarantidepressant, and again gradually reduce thedose while monitoring your symptoms.

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What happens if the medication prescribed hasnot helped me?

If the medication has not been helpful, yourhealthcare professional should usually consideroffering you a different antidepressant (selectedfrom those specifically recommended for PTSD),or offer you a medicine called olanzapine inaddition to your current medication.

Can medication help me with sleep problems?

If you are having trouble sleeping yourhealthcare professional may offer youmedication. This may be a sleeping tablet (for short-term use only), or one of theantidepressants (specifically recommended for PTSD) that helps with sleep.

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If you are offered antidepressant medicationyou could ask the following questions.

• How will the medication help me?

• How long will it take before I start to feelbetter?

• How long will I have to take it for?

• Will it be easy to stop taking it?

You should be told about possible sideeffects of antidepressants, but if you areunsure you could also ask the followingquestions.

• Does this medication have any side effects?

• Will the side effects affect my daily life, orphysical or psychological health?

• What should I do if I get any of these sideeffects?

• How long will the side effects last?

• Is there a leaflet or other written materialabout the medication that I can have?

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I have other illnesses or problemsbesides PTSD. Will this affect mytreatment for PTSD?

If you have PTSD and also have depression youshould be offered treatment for both. Usuallythe PTSD will be treated first, because depressionoften improves as the symptoms of PTSDimprove, but if you have severe depression, thedepression will usually be treated first.

If healthcare professionals think that you may beat risk of harming yourself or others, they shouldtry and deal with this problem first to make sureyou are safe.

If you take recreational drugs and/or alcohol,this may affect your treatment for PTSD, sohealthcare professionals should treat any drug or alcohol problem first.

If you have other personal and relationshipproblems that have been around for a long time you should still be offered trauma-focusedpsychological treatment, but you may receivetreatment for longer than 8 sessions.

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If you have lost a family member or friend dueto an unnatural or sudden death your emotionsmay be overwhelming, and you may have whatis sometimes called ‘traumatic grief’. Your GPshould also be able to provide you withinformation about professionals who havetraining and experience in this area. But if youthink you have PTSD, it is best to see your GP.

Will my treatment be affected if I amseeking compensation?

No. Healthcare professionals should not delaytreatment or refuse to treat you because you are seeking compensation as a result of atraumatic event.

Will I be offered any other kind ofhelp by healthcare professionals?

In addition to any support you are receivingfrom family members and/or carers, healthcareprofessionals should give you information onwhere to get further practical and social supportif you need it.

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What treatments areavailable for young people?

If you are a child or young person you should be offered a type of psychological treatment for PTSD called ‘trauma-focused cognitivebehavioural therapy (CBT)’ (for more informationsee page 14). You can receive this treatment ifyou have had PTSD for a short time or a longertime. It involves talking to a healthcareprofessional about what happened and how youare feeling. If this makes you feel very upset,your healthcare professional should try tounderstand and help you to take things slowly.

If you have developed PTSD recently (within the last month) and you feel very distressed, you should be offered psychological treatment(but this is not always appropriate for youngerchildren).

If you have had PTSD for months or yearsyou should also be offered psychologicaltreatment. You should normally see your doctorbetween 8 and 12 times (at least once a week).Each meeting should usually last for 1 hour, but when you talk about what happened to you, the meeting should usually last for aboutan hour and half. The same doctor should seeyou for all of your meetings.

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Usually, it is important that you receive most ofyour treatment on your own with the healthcareprofessional. But your healthcare professionalmay suggest that members of your family orcarers are involved in your treatment if he or she thinks it may help. This should be agreedwith you before it happens.

Healthcare professionals should tell you (and amember of your family if appropriate) that onlypsychological treatments that are designed forPTSD should be used to treat PTSD. There is littleevidence at the moment to show that othertreatments (such as play therapy, art therapy and family therapy) can help young people with PTSD.

You should not usually be offered medicines totreat your PTSD, because there is not enoughsupporting evidence to recommend suchtreatments in children and young people.

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Information for families andcarers

How can I support a family memberwith PTSD?

As a family member or a carer you can have an important role in providing practical andemotional support to someone with PTSD. If it is appropriate and the person with PTSDconsents, healthcare professionals should giveyou full information about common reactions to traumatic events, including the symptoms of PTSD and its course and treatment.

How can I find support for myself?

Supporting a person with PTSD may be quitedistressing. If this is the case, and you needfurther help, healthcare professionals should besympathetic and understanding, and offer youfurther information about self-help groups,support groups and voluntary organisations. You can find information about the importantrole of carers at the website www.carers.gov.uk

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If other members of the family have alsoexperienced the traumatic event (for example acar accident, or the death or near death, of arelative) they may also develop PTSD. If so, careand treatment should address the needs of thewhole family.

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Where you can find moreinformation

If you need further information about PTSD orthe care that you are receiving, ask your doctor,nurse or other member of your healthcare team.You can discuss the NICE guideline orinformation in this booklet with them.

If you want to read the other versionsof this guideline

There are four versions of this guideline:

• this one

• the full guideline, which has all therecommendations, information on how theywere developed and the evidence on whichthey were based

• the NICE guideline, which has all therecommendations

• the quick reference guide, which is a summaryof the NICE guideline.

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All versions of the guideline are available fromthe NICE website (www.nice.org.uk/CG026). This version and the quick reference guide arealso available from the NHS Response Line—phone 0870 1555 455 and give the referencenumber(s) of the booklets you want (N0849 forthis version, N0850 for this version in English andWelsh, and N0848 for the quick reference guide).

If you want more information aboutPTSD

NHS Direct may be a good starting point forfinding out more about PTSD. You can call NHS Direct on 0845 46 47 or visit the website at www.nhsdirect.nhs.uk orwww.nhsdirect.wales.nhs.uk

There may be support groups for people withPTSD in your area. Your doctor or nurse shouldbe able to give you more details. Informationabout local groups may also be available fromNHS Direct or your local library or CitizensAdvice Bureau.

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If you want to know about relatedNICE guidance

Information for the public on the followingrelated guidance can be found on the NICEwebsite.

• Anxiety: management of anxiety (panicdisorder, with or without agoraphobia, and generalised anxiety disorder) in adults in primary, secondary and communitycare. NICE Clinical Guideline No. 22 (December 2004). Available fromwww.nice.org.uk/CG022publicinfo

• Depression: management of depression inprimary and secondary care. NICE ClinicalGuideline No. 23 (December 2004). Availablefrom www.nice.org.uk/CG023publicinfo

• Self-harm: The short-term physical andpsychological management and secondaryprevention of self-harm in primary andsecondary care. NICE Clinical Guideline No. 16 (July 2004). Available fromwww.nice.org.uk/CG016publicinfo

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These can also be ordered from the NHSResponse Line on 0870 1555 455. For the anxiety information quote reference numberN0764 for a version in English and N0765 for aversion in English and Welsh; for depressionquote N0767 (English) and N0768 (English andWelsh); and for self-harm quote N0626 (English)and N0627 (English and Welsh).

NICE is in the process of developing thefollowing guidance (details available fromwww.nice.org.uk):

• Depression in children: identification andmanagement of depression in children andyoung people in primary care and specialistservices. NICE Clinical Guideline. (Publicationexpected August 2005.)

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N0849 1P 20k Mar 05 (ABA)

National Institute forClinical Excellence

MidCity Place71 High Holborn

LondonWC1V 6NA

www.nice.org.uk