Top Banner
Protein-DNA Interactions
28

Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Aug 10, 2020

Download

Documents

dariahiddleston
Welcome message from author
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
Page 1: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Protein-DNA Interactions

Page 2: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

The central dogma of biology

Page 3: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Genomic DNA

Page 4: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

DNA packaging

Page 5: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

DNA replication

Page 6: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

DNA replication

Page 7: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

The genetic code

Page 8: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Transcription of DNA

Page 9: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Translation of mRNA - Protein synthesis

Page 10: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

DNA structure

Page 11: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

DNA structure

Page 12: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

DNA structure

Page 13: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Protein-DNA interactionsMinor & Major grooves- Recognition patterns

Page 14: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Protein-DNA interactionsMinor & Major grooves- Recognition patterns

Page 15: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Protein-DNA interactionsMinor & Major grooves- Recognition patterns

Page 16: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Protein-DNA interactionsSequence specific vs. non-specific recognition

Page 17: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

The RNA polymerase

Page 18: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

The RNA polymerase

Page 19: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

The RNA polymeraseRNA synthesis begins at promoter sites

Page 20: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

The RNA polymeraseRNA synthesis begins at promoter sites

Page 21: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Gene regulationNegative regulation

Page 22: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Gene regulationNegative regulation

Lactose repressor

Page 23: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Gene regulationNegative regulation

Lactose repressor

Page 24: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Gene regulationPositive regulation

Page 25: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Gene regulationPositive regulation

cAMP Receptor Protein (CRP)

Page 26: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Gene regulationPositive regulation

Page 27: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Gene regulationPositive regulation

Page 28: Protein-DNA Interactions · Transcription of DNA sequence into RNA sequence RNA 1 RNA 2 RNA 3 Translation (on the ribosome) of RNA sequence into protein sequence and folding of protein

Gene regulationPositive regulation