1 Project No. 619230 Deliverable 3.2 Questionnaires on unmet technical needs to be filled in by SMEs and on unmet clinical needs to be filled in by medical staff Date of Delivery M3 Authors Francesca Rossi, Dissemination level Public WP 3 Version 01 Keywords Inventory, questionnaires, SMEs in Biophotonics, Hospitals, Agrifood Description This Deliverable describes some definition concerning future activities (inventory) of WP3, proposes the final templates of SMEs, clinical and Agrifood unmet needs. This OASIS project in funded by the European Union under the Information and Communication technologies (ICT) theme of the 7th Framework Programme. This document does not represent the opinion of the European Union, and the European Union is not responsible for any use that might be made of its content.
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Project No. 619230
Deliverable 3.2 Questionnaires on unmet technical needs
to be filled in by SMEs and on unmet clinical needs to be filled in by medical
staff Date of Delivery M3
Authors Francesca Rossi,
Dissemination level Public
WP 3
Version 01
Keywords Inventory, questionnaires, SMEs in Biophotonics, Hospitals, Agrifood
Description This Deliverable describes some definition concerning future activities (inventory) of WP3, proposes the final templates of SMEs, clinical and Agrifood unmet needs.
This OASIS project in funded by the European Union under the
Information and Communication technologies (ICT) theme of the 7th
Framework Programme.
This document does not represent the opinion of the European
Union, and the European Union is not responsible for any use that
3.3 General eligibility criteria for the inventory .................................................................................................. 5
4 Annex 1: SMEs Form ....................................................................................................................................... 7
5 Annex 2 Hospitals Form ................................................................................................................................. 22
6 Annex 3 Agrifood market actors form ............................................................................................................. 28
3
1 Introduction The Deliverable 3.2 reports the activities performed by the leader and co-leaders of WP3, related to the Task 3.1. The document provides the defined rules and definitions for the next scouting activities that will be performed in T3.2, the template of the questionnaire that will be used by all the partners to contact SMEs working in the field of Biophotonics Technologies and to record their needs; the template of the questionnaire that will be used by all the partners to contact the medical end-users to collect their unmet clinical needs that can be solved with Photonics-based Technologies; the template of the questionnaire that will be used by all the partners to contact the Agrifood market actors to collect their unmet needs that can be solved with Photonics-based Technologies. This deliverable is the second deliverable of WP3, whose main objective is to collect the needs of SMEs working in the Biophotonics, in the Medical Technology fields, and in Agrifood field in order to improve their international competitiveness thanks to Photonics- Based Technologies and Solutions. Another objective is to investigate the unmet medical needs from Hospitals and from Agrifood market actors, and that can be solved by Photonics- Based Technologies and Solutions. These objectives will be reached by collecting data on the SMEs located in each participant partner’s regions and clusters, on the research centres and on the hospitals. The first step in performing the inventory is to define common rules and definitions, a presentation letter and the forms that will be used by all the OASIS partners to scout new companies and their needs and to target the end-users needs. The deliverable D3.2 is part of the Task T3.1 (Inventory of SMEs targets in each clusters) and T3.2 (Inventory of unmet clinical and agrifood needs in each clusters and early analysis).
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2 Methods A preliminary activity performed by WP3 leader and co-leaders on T3.1 and T3.2 was to provide some definition in order to clarify the activities of the following tasks. After approval of the definition and rules, they worked on the forms, considering their previous experiences and proposing new approaches in order to easily integrate the information resulting from the WP2 activities and the WP3 activities. The Forms were discussed, integrated and corrected and finally approved. In the following paragraph the definitions and rules are reported. In the annexes the SMEs, Hospitals and Agrifood questionnaires are reported. The approved forms reported in the annexes will be used by all the partners to contact the SMEs, Hospitals and Agrifood market actors.
3 WP3 rules and definitions
3.1 WP3 Objectives
To record the SMEs and their unmet need from each cluster.
To record the unmet Medical (Hospitals) and Agrifood related needs.
To exploit the problems encountered by SMEs in the use of existing facilities.
To record the success stories of Biophotonics- based innovation transfer.
To design a roadmap to bring a fruitful collaboration with SMEs, facilities and clinical
environments, in order to develop new Photonics- based solutions to Life Science including
Health and Agri-Food.
3.2 Definitions SMEs involved in the project (contacted through the questionnaire) are micro, small and
medium enterprises working on the field of “Photonics”. A restricted number of large
companies should be involved in the project. The involved enterprises:
a) produce optical or photonic devices, sensors, microscopic, imaging, inspection
and analytic techniques, etc. that can have the end user market in the following
application areas:
Medicine / healthcare
Pharmaceutics
Food and water safety
Agriculture / AgriFood
Cosmetics
Veterinary medicine
Forensic Science
Biology
….
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b) Work in the previous applications area and need a
service/certification/consultants/R&D activities in the field of Photonics
c) Work in other application areas and want to find new markets in the previous
application areas
“Hospitals” involved in the project can be better defined as Department of Hospitals and
Clinics, with a characterization related to the particular medical/surgical field. The
“Hospitals” should indicate an unmet clinical need in the diagnosis, therapy, surgery, analysis
of a particular clinical problem, that can be solved with photonics based solutions.
Agrifood market actors: within this definition we include companies working in the field of
the agrifood, needing new biophotonics based systems for quality control, food safety,
characterization, production etc. Entities working in the Fish or Meat markets can be
involved. Network/clusters (both official and unofficial) of enterprises working in this field
can be contacted.
Success story: in the framework of this project a success story is the fruitful collaboration of
an SME with a Research Center/ University/ Facility (as defined in WP2) and/or Hospitals
using photonics technologies to solve unmet problems or leading to:
o The design of a new tool/instrument as an innovation transfer activity;
o The funding of join activities through a successful EU/National/Regional Project;
o Awards recognizing the collaboration and the innovation activities;
o Patent authored by researchers and enterprises;
o Successful preclinical/clinical tests of an instruments/procedures
o A new product developed within the collaboration of a facility/Hospital and an SME
o The commercialization and the diffusion in the market of a new photonic technology
3.3 General eligibility criteria for the inventory SMEs, Hospitals and Agrifood market actors involved in WP3 activities are in a first priority located in
the region or country covered by the 9 photonics clusters of the OASIS consortium, namely:
- Optitec / PACA and Languedoc-Roussillon Regions
- CNR / Tuscany Region
- PhotonicSweden / Sweden
- OpTecBB / Brandenburg Region
- Politecnico Di Milano / Lombardia Region
- SECPhO / Spain
- Photonics Netherlands / Netherlands
- Photonics Bretagne / Bretagne Region
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- Swansea University / Wales Region
In a second phase (t0+12 months), the inventory will be open to other regions / countries of the
European Community.
3.4 Activities The activities of WP3 will be:
T3.1 Inventory of SMEs needs in each clusters
T3.2 Inventory of unmet clinical and agrifood needs in each clusters and early analysis
T3.3 Collecting success stories on innovation transfer in Biophotonics, Medical Technology and
Agrifood related Technology
T3.4 Roadmap of the needs of SMEs in the next years
The activities will be performed following the previous definitions and eligibility criteria as an
indication, respecting possible differentiation related to the specificity of each cluster. Feedback on
services/facilities (if any) will be shared with WP2.
4 Annex 1: SMEs Form
Inventory on SME's Technology Needs
8
The OASIS Support Action (CSA 619230 "Open the Access to photonics life Science Infrastructure for SMEs" www.fp7-oasis.eu) is a European project started in December 2013 and aimed at facilitating the access of SMEs to life science laboratories, facilities and infrastructures, in order to support creating value and employment in the technological sector of Photonics for the Life Science and Health. Nine photonics clusters from seven countries (France, UK, Germany, Sweden, Netherlands, Italy, Spain) are involved in initiatives supporting Biophotonics at the regional or national level, such as realizing an inventory to geographically map the European life science facilities useful for photonics SMEs, collect and analyze the demand of innovation from SMEs and hospitals, design services to improve collaboration frameworks between facilities, SMEs, hospitals, industrials in product development and validation. This Questionnaire is aimed at collecting the needs of SMEs working in biophotonics, in the medical technology fields, and in the agri-food field in order to improve their international competitiveness thanks to photonics-based technologies and solutions. We thank you for your collaboration and we are open to any request, comment, suggestion, which can be addressed to XXXXXXX YYYYYY - Email: zzzzz@kkkkkkk. Thank you Privacy disclaimer statement
8. Brief description of the expertise your company (max 500 characters):
Manager (Lab): Owner/Director/CEO (Company): Number of Staff: Number of Researchers / engineers: Turnover (Company): M€
Inventory on SME's Technology Needs
10
Start up date:
9. Indicate your main sector of interest (check all that apply).
Medicine / healthcare
Pharmaceutics
Food and water safety
Agriculture / AgriFood
Biology
Cosmetics
Veterinary medicine
Forensic Science
Other
If “Other”, please specify (max 200 characters):
10. Please indicate if your activity is related with the following
surgical/therapeutic/diagnostic areas (check all that apply):
Aesthetic and therapeutic laser and light sources
Clinical applications of Biophotonics and
applications in doctors’ practices
Endogenous chromphores, photosensitisers
Endoscopes
In-vivo cellular diagnostics, in-vivo histology,
pathology
Nanomedicine
Ophthalmic instruments
Optical biochips and biosensors
Optical delivery systems for diagnostics and
therapy
Photonic for cell and tissue manipulation
Inventory on SME's Technology Needs
11
Photonics for cancer diagnosis and therapy
Photonics for cell and molecular biology
Photonics for minimally-invasive therapies
Photonics for non- and minimally-invasive
diagnosis
Photonics for point-of-care diagnosis
Photonics for preventive medicine, advanced
and early diagnosis
Surgical laser systems
Other
If “Other”, please specify (max 500 characters):
11. Skills and services your company needs: (check all that apply):
Pooling of equipment
Training
Expertise
Preclinical trials
Clinical trials
Other
If “Other”, please specify (max 500 characters):
12. Examples of previous experiences in working with Facilities, Research Centers, Hospitals…: joint projects, transfer of innovation, services, contracts, patents… (max 500 characters)
Inventory on SME's Technology Needs
12
Title1: description1
Title2: description2
…..
13. Please indicate some critical aspects you encountered in your experiences in working with or for Facilities, Research Centers, Hospitals…: (max 500 characters)
14. If you have access to, or aware of other databases/Networks/clusters, not only
related to Photonics, but also to clinical/biological or agri-food data, please indicate them:
Inventory on SME's Technology Needs
13
Photonics technologies you develop [D], purchase [P] and need [N] (check all that apply)
Technologies D P N
Cameras and Imaging systems: camera shutters
CCD cameras
CMOS cameras
high-speed cameras
image intensifiers
infrared/thermal cameras
line-scan cameras
machine vision systems
miniature imaging systems
motion analysis systems
on-board cameras
other camera/imaging systems
photographic cameras
spectral imaging cameras
stereoscopic cameras
X-ray imaging
Other (specify):
Computing, Data Processing Hardware compression/ decompression
Spectroscopy Devices and Equipment fourier transform
FTIR
Infrared
laser induced breakdown spectroscopy
LWIR
near-infrared
photoacoustic
Raman
Spectrometers
Ultraviolet
X-ray
Other (specify):
Test and Measurement, Metrology 2D profilers
3D profilers
asphere metrology tools
Autocollimator
beam profilers
beam quality measurement
defect/surface quality
distance measurement
fiber optics test and measurement
Inventory on SME's Technology Needs
21
interferometer, white light/roughness to...
interferometers, including shape of optics
laser energy measurement
LED characterization/measurement
light measurements
monochromators
oscilloscopes
other instrumentation and test equipment
power and energy meters
radiometers and photometers
spectrum analyzers
surface profiler
wavefront meters
wavelength meters
Other (specify):
Vacuum, Cooling, Gas Handling Equipment
cooling equipment
Cooling equipment and systems
gas handling equipment
Vacuum equipment
Other (specify):
5 Annex 2 Hospitals Form
Inventory of Unmet Clinical Needs
23
The OASIS Support Action (CSA 619230 "Open the Access to photonics life Science Infrastructure for SMEs" www.fp7-oasis.eu) is a European project started in December 2013 and aimed at facilitating the access of SMEs to Biophotonics laboratories, facilities and infrastructures, in order to support creating value and employment in the technological sector of Photonics for the Life Science and Health. Nine photonics clusters from seven countries (France, UK, Germany, Sweden, Netherlands, Italy, Spain) are involved in initiatives supporting Biophotonics at the regional or national level, such as realizing an inventory to geographically map the European Biophotonics facilities, collect and analyze the demand of innovation from SMEs and Hospitals, design services to improve collaboration frameworks between facilities, SMEs, hospitals, industrials in product development and validation. This Questionnaire is aimed at collecting from Hospital Departments and Clinics their technological interests, expectations, new improvements which may be offered in the Medical fields by Biophotonics, i.e. Photonics for the Life Science and Health (see more details in the Appendix at the end of this document). We thank you for your collaboration and we are open to any request, comment, suggestion, which can be addressed to XXXXXXX YYYYYY - Email: zzzzz@kkkkkkk. Thank you Add at the end a PRIVACY DISCLAIMER.
25. Skills and services your Hospital/Dept needs: (check all that apply):
Pooling of equipment
Training
Expertise
Preclinical trials
Clinical trials
Other
If “Other”, please specify (200 characters max):
26. Examples of previous experiences in working with Facilities, Research Centers,
Companies…: joint projects, transfer of innovation, services, contracts, patents… (max 500 characters)
Title1: description1
Title2: description2
…..
27. Please indicate some critical aspects you encountered in your experiences in working with or for Facilities, Research Centers, Hospitals…: (max 500 characters)
…….
28. If you have access to, or aware of other databases/Networks/clusters, not only
related to photonics, but also to clinical/biological or agrifood data, please indicate them:
Inventory of Unmet Clinical Needs
27
Appendix - Details on the aims of OASIS to support Life Sciences and Health
Photonics21 WG 3 “Life Science and Health” FP 8 Vision Paper has identified the areas where
photonics will play a key role in Life Science. Most of these areas are still at the R&D development
phase. It is still missing a bridge to transfer these high-value concepts in innovation and products.
In this regards, OASIS is aimed at addressing technological development and validation in:
Preclinical research
o Optical imaging is contributing strongly to preclinical research because it is a non-invasive
and non-radiative method that works in real time at variable spatial (nm to mm range) and
temporal (μsec to minutes) resolutions, with high sensitivity (femtomolar to picomolar range),
from whole-body to sub-cellular scales in small animal studies.
o The passage of Optical Imaging to the clinic is now linked to the availability of injectable
tracers, and also suffers from limitations like a insufficient depth of investigation and a poor
linearity of the measures.
New diagnostic methods
o Widespread application of diffuse spectral optical imaging to report on the endogenous
fluorescent properties of tissues and to provide information such as total hemoglobin
concentration, blood oxygen saturation, water and lipid concentration without the injection of
an exogenous contrast agent,
o Molecular imaging by targeted fluorescent markers to detect, localize and quantify tissues
of interest,
o Opto-acoustic imaging to get a high resolution reconstruction of optically contrasted
structures in deep tissues.
o Intra-vital in vivo microscopy will also contribute significantly to improve the diagnosis of
several pathologies in the clinic. Cellular microscopy techniques (confocal, spectroscopy,
Raman, etc.) are already available to provide accurate characterization of tissues but the true
challenge now is to bring these microscopic optical approaches into endoscopic instruments.
New treatments
o Non-invasive or minimally invasive, but highly targeted treatments based on light, such as
Photodynamic therapy
o Image-guided surgery and therapy through endoscopic imaging
o UV decontamination for the development of the “dry factory” in Agrifood industry
Monitoring
o On-the-field investigation in Agricultural production with data transmitted over mobile
connections
o High bandwidth optical communication in combination with diagnostic imaging will enable
early detection of medical problems through the monitoring of data from patients.
6 Annex 3 Agrifood market actors form
Inventory of Unmet Agrifood Needs
29
The OASIS Support Action (CSA 619230 "Open the Access to photonics life Science Infrastructure for SMEs" www.fp7-oasis.eu) is a European project started in December 2013 and aimed at facilitating the access of SMEs to life science laboratories, facilities and infrastructures, in order to support creating value and employment in the technological sector of Photonics for the Life Science and Health. Nine photonics clusters from seven countries (France, UK, Germany, Sweden, Netherlands, Italy, Spain) are involved in initiatives supporting Biophotonics at the regional or national level, such as realizing an inventory to geographically map the European Biophotonics facilities, collect and analyze the demand of innovation from SMEs, Hospitals and Agrifood market actors, design services to improve collaboration frameworks between facilities, SMEs, hospitals and agrifood related end users, industrials in product development and validation. This Questionnaire is aimed at collecting from Agrifood market actors their technological interests, expectations, new improvements which may be offered in this field by Biophotonics, i.e. Photonics for the Life Science (see more details in the Appendix at the end of this document). We thank you for your collaboration and we are open to any request, comment, suggestion, which can be addressed to XXXXXXX YYYYYY - Email: zzzzz@kkkkkkk. Thank you Add at the end a PRIVACY DISCLAIMER.
38. Skills and services your company needs: (check all that apply):
Pooling of equipment
Training
Expertise
Other
If “Other”, please specify (200 characters max):
39. Examples of previous experiences in working with Facilities, Research Centers,
Companies…: joint projects, transfer of innovation, services, contracts, patents… (max 500 characters)
Title1: description1
Title2: description2
…..
40. Please indicate some critical aspects you encountered in your experiences in working with or for Facilities, Research Centers…: (max 500 characters)
…….
41. If you have access to, or aware of other databases/Networks/clusters, not only
related to photonics, but also to clinical/biological or agrifood data, please indicate them:
Inventory of Unmet Agrifood Needs
33
Appendix - Details on the aims of OASIS to support Life Sciences and Health
Photonics21 WG 3 “Life Science and Health” FP 8 Vision Paper has identified the areas where
photonics will play a key role in Life Science. Most of these areas are still at the R&D development
phase. It is still missing a bridge to transfer these high-value concepts in innovation and products.
In this regards, OASIS is aimed at addressing technological development and validation in:
Preclinical research
o Optical imaging is contributing strongly to preclinical research because it is a non-invasive
and non-radiative method that works in real time at variable spatial (nm to mm range) and
temporal (μsec to minutes) resolutions, with high sensitivity (femtomolar to picomolar range),
from whole-body to sub-cellular scales in small animal studies.
o The passage of Optical Imaging to the clinic is now linked to the availability of injectable
tracers, and also suffers from limitations like an insufficient depth of investigation and a poor
linearity of the measures.
New diagnostic methods
o Widespread application of diffuse spectral optical imaging to report on the endogenous
fluorescent properties of tissues and to provide information such as total hemoglobin
concentration, blood oxygen saturation, water and lipid concentration without the injection of
an exogenous contrast agent,
o Molecular imaging by targeted fluorescent markers to detect, localize and quantify tissues
of interest,
o Opto-acoustic imaging to get a high resolution reconstruction of optically contrasted
structures in deep tissues.
o Intra-vital in vivo microscopy will also contribute significantly to improve the diagnosis of
several pathologies in the clinic. Cellular microscopy techniques (confocal, spectroscopy,
Raman, etc.) are already available to provide accurate characterization of tissues but the true
challenge now is to bring these microscopic optical approaches into endoscopic instruments.
New treatments
o Non-invasive or minimally invasive, but highly targeted treatments based on light, such as
Photodynamic therapy
o Image-guided surgery and therapy through endoscopic imaging
o UV decontamination for the development of the “dry factory” in Agrifood industry
Monitoring
o On-the-field investigation in Agricultural production with data transmitted over mobile
connections
o High bandwidth optical communication in combination with diagnostic imaging will enable
early detection of medical problems through the monitoring of data from patients.