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Progress Against Lymphoma
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Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Mar 27, 2015

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Page 1: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against

Lymphoma

Page 2: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

1970–1979

Page 3: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

1970–19791974: FDA approves doxorubicin, a vital part of combination chemotherapy

Page 4: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

1970–19791975: New chemotherapy regimen boosts Hodgkin lymphoma cure rates to 70 percent

1975: Era of bone marrow transplantation begins – extending lives of many patients with leukemia and lymphoma

Page 5: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

1970–19791976: CHOP regimen boosts cure rates for non-Hodgkin lymphoma

Page 6: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

1980–1989

Page 7: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

1980–19891980: Imaging tests begin replacing surgery for Hodgkin lymphoma staging

Page 8: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

1980–1989Late 1980s: Benzene established to cause blood cancers

Page 9: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

1990–1999

Page 10: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

1990–19991993: Mantle cell lymphoma recognized as a subtype of non-Hodgkin lymphoma

Page 11: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

1990–19991990s: Research suggests a therapeutic vaccine for follicular lymphoma could be possible

1995: Lymphocyte transfusions re-induce leukemia remissions

1995: Bone marrow transplantation improves survival for relapsed non-Hodgkin lymphoma

Page 12: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

1990–19991997: FDA approves first-ever targeted cancer drug, rituximab

1997: Classification system established for non-Hodgkin lymphoma

Page 13: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

1990–19991998: New technique enables older patients to undergo life-saving stem cell transplants

Page 14: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

2000–Present

Page 15: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

2000–Present2001: Scientists discover that common type of lymphoma is two distinct diseases

Page 16: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

2000–Present2002: Adding rituximab to ''CHOP'' chemotherapy boosts survival

2002: Radioimmunotherapy introduced to treat lymphoma

Page 17: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

2000–Present2005: Bortezomib shrinks tumors in mantle cell lymphoma

Page 18: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

2000–Present2007: PET scanning helps guide lymphoma treatment

Page 19: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

2000–Present2008: First drug approved specifically for T-cell lymphoma treatment

Page 20: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

Five-Year Survival

42

47

52

57

62

67

72

1975

1977

1979

1981

1983

1985

1987

1989

1991

1993

1995

1997

1999

2001

2003

2005

2007

2009

Year of Diagnosis

% o

f Pa

tien

ts S

urv

ivin

g F

ive

Ye

ars

Source: National Cancer Institute

Page 21: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

Mortality

4

5

6

7

8

9

10

11

12

1970

1972

1974

1976

1978

1980

1982

1984

1986

1988

1990

1992

1994

1996

1998

2000

2002

2004

2006

2008

2010

Year of Death

Ca

nce

r D

ea

ths

pe

r 1

00

,00

0 P

eo

ple

Source: National Cancer Institute

Page 22: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

Progress Against Lymphoma

New Cases

11

13

15

17

19

21

23

25

27

1973

1975

1977

1979

1981

1983

1985

1987

1989

1991

1993

1995

1997

1999

2001

2003

2005

2007

2009

Year of Diagnosis

Ne

w C

an

cer

Ca

ses

pe

r 1

00

,00

0 P

eo

ple

Source: National Cancer Institute

Page 23: Progress Against Lymphoma. 1970–1979 Progress Against Lymphoma 1970–1979 1974: FDA approves doxorubicin, a vital part of combination chemotherapy.

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