Updated: Nov. 14, 2016 CURRICULUM VITAE Alessandro Iannaccone, MD, MS, FARVO Professor of Ophthalmology Director, Center for Retinal Degenerations and Ophthalmic Genetic Diseases CITIZENSHIP STATUS: Dual – Italian and American LANGUAGES: Fully fluent in English and Italian Knowledge of medical and conversational Spanish and Portuguese Basic knowledge of French EDUCATION: Pre-graduate miscellanea June – Aug. 81 Full-time Course, English Program for Foreign Students (EPFS), University of Pennsylvania, Bennett Hall, 34th and Walnut Street, Philadelphia, PA 19104 (7th level) 1982 First Certificate of English, British Institute of Rome, Via Quattro Fontane 5, 00184 Rome, Italy July 1983 General Certificate of Education, Dante Alighieri High School, Via Ennio Quirino Visconti 6, 00193 Rome, Italy Aug. – Oct. 83 Full-time Course, EPFS, University of Pennsylvania, Bennett Hall, 34th and Walnut Street, Philadelphia, PA 19104 (College Skills level) Undergraduate N/A (College is not part of the standard Italian educational system: pre-clinical basic science courses are included in the standard 6-year Medical School program) Graduate/Medical School Nov. 83 – Jul. 89 University of Rome “Sapienza”, School of Medicine (6-yr. program), P.le A. Moro 5, 00185 Rome, Italy (Registration Number: 03053907 aka C53907) July 20, 1989 M.D. degree with full marks and honors ( 110/110 e lode) Internship (rotations) May 89 – Nov. 89 Internal Medicine, III Clinica Medica (Prof. Bonomo) Obstetrics and Gynecology, Clinica Ostetrica e Ginecologica (Prof. Pachì) Ophthalmology, Clinica Oculistica (Prof. Pannarale) University of Rome “Sapienza”, Policlinico Umberto I, Viale del Policlinico 1, Rome, Italy
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Updated: Nov. 14, 2016
CURRICULUM VITAE
Alessandro Iannaccone, MD, MS, FARVO
Professor of Ophthalmology Director, Center for Retinal Degenerations and Ophthalmic Genetic Diseases
CITIZENSHIP STATUS: Dual – Italian and American LANGUAGES: Fully fluent in English and Italian
Knowledge of medical and conversational Spanish and Portuguese Basic knowledge of French
EDUCATION: Pre-graduate miscellanea June – Aug. 81 Full-time Course, English Program for Foreign Students (EPFS), University of
Pennsylvania, Bennett Hall, 34th and Walnut Street, Philadelphia, PA 19104 (7th level) 1982 First Certificate of English, British Institute of Rome, Via Quattro Fontane 5, 00184
Rome, Italy July 1983 General Certificate of Education, Dante Alighieri High School, Via Ennio Quirino
Visconti 6, 00193 Rome, Italy Aug. – Oct. 83 Full-time Course, EPFS, University of Pennsylvania, Bennett Hall, 34th and Walnut
Street, Philadelphia, PA 19104 (College Skills level) Undergraduate N/A (College is not part of the standard Italian educational system: pre-clinical basic science
courses are included in the standard 6-year Medical School program) Graduate/Medical School Nov. 83 – Jul. 89 University of Rome “Sapienza”, School of Medicine (6-yr. program), P.le A. Moro 5, 00185
Rome, Italy (Registration Number: 03053907 aka C53907) July 20, 1989 M.D. degree with full marks and honors (110/110 e lode) Internship (rotations) May 89 – Nov. 89 Internal Medicine, III Clinica Medica (Prof. Bonomo)
Obstetrics and Gynecology, Clinica Ostetrica e Ginecologica (Prof. Pachì) Ophthalmology, Clinica Oculistica (Prof. Pannarale) University of Rome “Sapienza”, Policlinico Umberto I, Viale del Policlinico 1, Rome, Italy
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 2 of 35
Residency Nov. 89 – Jul. 93 II School of Ophthalmology, Institute of Ophthalmology, University of Rome “Sapienza”,
Viale del Policlinico 1, 00185 Rome, Italy, Prof. M.R. Pannarale, Chairman (Registration Number: CT9509)
July 14, 1993 Ophthalmology diploma with full marks and honors (70/70 e lode)
Post-Graduate Training and Education Aug. 95 – Jul. 96 Retina Research Fellow, Scheie Eye Institute, University of Pennsylvania, 51 N. 39th
Street (Myrin Circle), Philadelphia, PA 19104 (Dr. S.G. Jacobson, Fellowship Program Director; Drs. A.M. Laties, J.E. Grunwald, E.N. Pugh, secondary mentors)
Nov. 96 – Aug. 98 Clinical and Research Fellow, Pediatric Retinal and Optic Nerve Diseases, Department
of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN (Dr. N.C. Kerr, Program Director)
April 29, 2000 ARVO Saturday Education Courses, Clinical Trials in Eye Research: A Hands-on
Workshop with the Experts, Drs. Maureen Maguire, Roy Beck, Frederick Ferris, Sheila West, Course Co-organizers
April 28, 2001 ARVO Saturday Education Courses, From Twin to Gene Function: An Overview of
Statistical Genetics. Dr. Donald Zack, Course Moderator Jan. 00 – May 03 M.S. degree, Master of Science in Epidemiology, University of Tennessee HSC,
College of Graduate Health Sciences, Memphis, TN (Dr. Stephen B. Kritchevsky, Program director and research advisor) – Thesis: Natural History of Visual Function Loss in Usher Syndrome Type 2 (defended: 12/11/02 – approved: 01/22/03)
April 30, 2005 ARVO Saturday Educational Courses, Nanotechnology and Nanomedicine:
Applications for Vision Research. Drs. Paul Sieving and Richard Fisher, National Eye Institute, Course Co-organizers
UNIVERSITY AND HOSPITAL APPOINTMENTS Sept. 97 – Dec. 05 Founding Director , Lions Visual Function Diagnostic Laboratory, Department of
Ophthalmology, Le Bonheur Children’s Medical Center, University of Tennessee HSC
(UTHSC), Memphis, TN Sept. 98 – June 04 Assistant Professor, non-tenure track, Department of Ophthalmology, UTHSC,
Memphis, TN July 04 – Dec. 2015 Associate Professor, non-tenure track, Department of Ophthalmology, UTHSC,
Memphis, TN Dec. 98 – Dec. 05 Director, Retinal Degeneration Referral Center, Department of Ophthalmology, Le
Bonheur Children’s Medical Center, UTHSC, Memphis, TN Jan. 99 – Dec. 2015 Member, Neuroscience Institute, Univ. of Tennessee HSC, Memphis, TN
Jan. 06 – Dec. 2015 Director, Retinal Degeneration & Ophthalmic Genetics Service, Department of
Ophthalmology, Hamilton Eye Institute, UTHSC, Memphis, TN Jan. 06 – Dec. 2015 Founding Director, Lions’ Visual Function Diagnostic Laboratory, Department of
Ophthalmology, Hamilton Eye Institute, UTHSC, Memphis, TN Sept. 1 – present Professor, non- tenure track, Dept. Ophthalmology, Duke Eye Center, Duke University
Medical Center, Durham, NC Sept. 1 – present Director, Center for Retinal Degenerations and Ophthalmic Genetic Diseases, Duke Eye
Center, Duke University Medical Center, Durham, NC
Hospital Privileges July 99 – Sept. 2015 Le Bonheur Children’s Medical Center, Memphis, TN, Consulting Staff Member
(affiliated with Univ. of Tennessee HSC, Memphis, TN) Aug. 99 – July 04 UT Bowld Hospital, University of Tennessee, Memphis, TN Active Staff Member
(affiliated with UTHSC, Memphis, TN) – privileges ended due to hospital closure)
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 3 of 35
Sept. 99 – Sept. 2015 Regional One Health (previously known as The Med Plex County Hospital), Memphis, TN, Active Staff Member until March 2009, Courtesy Staff Member thereafter (affiliated with UTHSC, Memphis, TN)
May 04 – Sept. 2015 Methodist University Hospital, Memphis, TN, Active Staff Member (affiliated with
UTHSC, Memphis, TN) Jan. 14 – Sept. 2015 Baptist Memorial Hospital – Metro (core Ophthalmology privileges, Baptist Eye Centre,
Baptist Women’s Hospital, Memphis, TN) Oct. 8 – present Duke University Hospital and affiliated institutions, Duke Eye Center, Duke University
Medical Center, Durham, NC OTHER PROFESSIONAL EXPERIENCE AND QUALIFICATIONS
Aug. 89 – Aug. 93 Voluntary Service, as intern and resident in ophthalmology, Center for Inherited
Degenerative Retinal Disorders, Institute of Ophthalmology, University La Sapienza, Rome, Italy (outpatient clinic and visual function & electrophysiology service)
July 91 – Aug. 91 Visiting M.D., Retina Service of the Scheie Eye Institute (Drs. S.L. Fine, J.E. Grunwald, A.J. Brucker) and at Oncology Service of the Wills Eye Hospital (Dr. J.A. Shields), Philadelphia, PA
1991 – 1994 Patient Advocacy Representative, Social Security Disability Applications Committee, Montesacro Local State Hospital (USL), Rome, Italy
1991 – 1995 Private Consultant, Patient Advocacy and Social Security Disability Applications, Province of Rome, Italy
Aug. 93 Visiting Ophthalmologist, Retinal Degeneration Center, Jules Stein Eye Institute, UCLA, CA (Dr. J.R. Heckenlively)
Sept. 93 – July 95 Voluntary Attending Ophthalmologist, Center for Inherited Degenerative Retinal Disorders, Institute of Ophthalmology, University La Sapienza, Rome, Italy (outpatient clinic and electrophysiology service)
Sept. 93 – Jan. 2014 Private Practice Consultant, Rome, Italy (RP and allied disorders, AMD, and medical retina, visual psychophysics and electro-diagnostics, retinal imaging, retinal laser photocoagulations, periocular and intravitreal injections)
Feb. – Apr. 94 Visiting Ophthalmologist, Instituto Brasiliense de Olhos, Brasília, DF, Brasíl (Dr. J.L. Pacini-Costa, director)
2007 – present Fellow, American Board of Disability Analysts (F.A.B.D.A.), Nashville, TN Nov. 09 – Dec. 11 Private Consultant, Eisai, Inc., Woodcliff Lake, NJ (provided to company expertise with
clinical trial protocol design and forms, with special reference to ERG testing methods, protocols, and interpretation of test outcomes during trials of drugs for neurodegenerative diseases) – Contact: Dr. Michael Everson, PhD, Associate Director, [email protected]
Apr. 10 – Aug. 13 Private Consultant, Apeliotus Technologies, Inc., Atlanta, GA (served as fundus photography expert reader for the company in the conduction of multi-center study of dark adaptation abnormalities in age-related macular degeneration) – Contact: John Edwards, CEO, [email protected]
Feb. 2014 – present Ophthalmic Clinical Consultant, Retinal Degenerations and Ophthalmic Genetics, MetaMedica, San Raffaele Hospital Group, Rome, Italy (RP and allied disorders, AMD, and medical retinal conditions, visual psychophysics and electro-diagnostics, retinal imaging, retinal laser photocoagulations, periocular and intravitreal injections) – Contact: Ms. Irina Balaj, COO, [email protected]
March 2015 – present KOL Consultant, ClearView Healthcare Partners, Newton, MA (provide expert opinion to
investors on treatment approaches being developed for retinal dystrophies and
degenerations) May 2015 – present KOL Consultant, GLG Group, San Francisco, CA (provide expert opinion to investors on
treatment approaches being developed for retinal dystrophies and degenerations)
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 4 of 35
Nov. 2015 – present KOL Consultant, Huron Consulting Group, New York, NY (provide expert opinion to investors on treatment approaches being developed for retinal dystrophies and degenerations)
Nov. 2015 – present KOL Consultant, ECRI Institute, Plymouth Meeting, PA (provide expert opinion to investors on retinal prosthetics)
Jan. – Aug. 2016 Unpaid Consultant, University of Tennessee Health Science Center, Dept. of Pharmaceutical Sciences, Memphis, TN (project on autoimmunity of macular degeneration) – Contact: Francesco Giorgianni, PhD, MBA, PI, [email protected]
Jan. 2016 – present Consultant, Ionis Pharmaceuticals, Carlsbad, CA (Clinical development and testing of therapies for retinal diseases, including various imaging, efficacy and safety endpoints assessments) – Contact: Michael L. McCaleb, PhD, [email protected]
March 2016 – present Consultant, Advance Medical, Inc., Westwood, MA (provide expert clinical review of
complex medical retinal cases, with special emphasis on retinal/macular dystrophies
and/or degenerations and other rare such disorders) – Contact: Ryan Zantua, MD,
Assistant Medical Director, [email protected] April and August 2016 Visiting Ophthalmologist, Center for Retinal and Macular Degeneration, Kellogg Eye
Center, University of Michigan, MI (Host: Dr. J.R. Heckenlively, Director; Far Vision
Foundation, sponsor) – Contact: [email protected] May – Sept. 2016 Consultant, EyeCRO, Oklahoma City, OK (provide clinical and translational research expertise
applied to the study and treatment of retinal degenerative diseases) – Contact: Rafal
Farjo, PhD, CEO, [email protected] HONORS AND AWARDS (includes select grants and contracts): Prizes, Awards and Other Recognitions
Feb. 1991 First prize, Italian Association for retinitis pigmentosa and low vision (AIRPI)
Dec. 1993 First prize, best poster presentation, 1st National Retinitis Pigmentosa Day, Rome, Italy.
Nov. 1997 Italian Society of Ophthalmology (SOI) Young Investigator Award
March 1998 ISER Travel Fellowship Award
December 1998 ISCEV Travel Grant
2001 Recipient, Certificate of Special Recognition for Outstanding Contribution, 2001
Memphis Challenge Program
2003 – 2007 Recipient, Career Development Award, Research to Prevent Blindness, Inc., New
York, NY
2007 America’s Top Physicians, Ophthalmology, Consumer’s Research Council of America
May 3, 2009 Recipient, 2009 ARVO/Alcon Early Career Clinician-Scientist Research Award
July 2012 Recipient, Physician-Scientist Award, Research to Prevent Blindness, Inc., New
York, NY
May 2014 Nomination, 2014 PhDA Postdoctoral Research Trainee Outstanding Mentor Academy
Award, UTSHC, Memphis, TN
Dec. 2015 Recipient, ARVO Silver Fellow status (Class of 2016)
2000 – 2001 Research Agreement (co-P.I.), Pharmaceutical Company
2000 – 2001 Grant Recipient (P.I.), Le Bonheur Research Grant Program, Memphis, TN
2000 – 2001 Grant Recipient (P.I.), Pharmaceutical Company
2001 – 2002 Co-Investigator, Prevention of Age-Related Macular Degeneration in the Women’s Health
Initiative Hormone Replacement Therapy Clinical Trial (Women ’s Health Initiative - Sight Examination Study), Wyeth-Ayerst (Ancillary Study to multi-center NIH-funded Women’s
Health Initiative (K.C. Johnson, M.D., M.P.H., UTHSC Preventive Medicine, Site P.I.)
2001 – 2003 Grant Recipient (P.I., A.J. Reiner, Ph.D., UTHSC Neuroscience, Co-P.I.), University of
Tennessee Vascular Biology Partnership Program
2001 – 2007 Grant Recipient (P.I.), K23 Patient-Oriented Mentored Research Career
Development Award, Grant EY000409, NEI, NIH, Bethesda, MD
2003 – 2004 Grant Recipient (P.I.), University of Tennessee Department of Ophthalmology Intramural
RPB Grant Program
2003 – 2005 Co-Investigator, International Retinal Research Foundation Grant, Birmingham, AL (P.I.:
M.M. Jablonski, UTHSC Ophthalmology, Ph.D.)
2003 – 2005 Grant Recipient (P.I.), Fight for Sight Foundn. Grant-in-Aid Program, New York, NY
2004 – 2006 Co-Investigator, American Health Assistance Foundation Macular Degeneration Research
Program Grant, New York, NY (P.I.: E.J. Johnson, PhD, Tufts University, Boston, MA)
2005 – 2006 Grant Recipient (P.I., M.M. Jablonski, Ph.D., Co-PI), Herbert and Mary Shainberg
Neuroscience Research Program, Memphis, TN
Other Honors Oct. 1, 2002 Session Moderator, Platform Session IIa, Mechanisms of Retinal Degeneration and Cell Death, X International Symposium on Retinal Degeneration, Bürgenstock,
Switzerland, Sept. 30 – Oct. 5, 2002
Oct. 1, 2002 Session Moderator, Platform Session IIb, Usher Syndrome: Models, Mechanisms and Therapy, X International Symposium on Retinal Degeneration, Bürgenstock,
Switzerland, Sept. 30 – Oct. 5, 2002
Sept. 11, 2003 Featured investigator, Channel 3 News Center for Discovery Researchers Collaborate to Find Cures of Eyesight Diseases, by Cheryl Kepes http://www.wreg.com/Global/story.asp?S=1438844&nav=CsqEHwak Dec. 21, 2003 Featured Investigator, Macular Degeneration Study, The Link (page 2) and press release
Issue 2, Senior Services’ Alliance for the Blind and Visually Impaired, Memphis, TN
March 7, 2005 Featured Investigator, Research to Prevent Blindness grant receipt announcement,
UTHSC News Center Press Release and Commercial Appeal, Memphis, TN Jan. 2006 Featured Investigator, Retinal Degeneration Care Relocates to Hamilton Eye Institute,
Service focuses on hereditary eye disease, clinical research, The Link (page 3) July 2006 Featured Investigator, Eye Institute to Participate in Macular Degeneration Trial, The
Record, UTHSC newsletter (page 7)
January 26, 2007 Meet-the-Docs Invited Panel Member, Foundation Fighting Blindness Study Section
Meeting, Orlando Omni Resort at ChampionsGate, Orlando, FL July 20-22, 2007 Invited Speaker, VISIONS 2007, Foundation Fighting Blindness National Conference,
Overland Park, KS
Jan. 2008 Featured Investigator, Staying Focused – Researchers are exploring new treatments for age-related macular degeneration, Memphis Magazine, URL:
http://www.memphisflyer.com/gyrobase/Content?oid=38868 Feb. 2008 Finalist, Associate Dean for Health Career Programs’ position, UTHSC College of
Graduate Health Sciences, Memphis, TN
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 6 of 35
Sept. 2008 Featured Investigator, Memphis VisionWalk Slated on October 18, The Link (page 2 –
honorary chair of event)
Oct. 14, 2008 Featured investigator, Channel 3 Live at Nine show, Retinal Degenerative Diseases
and VisionWalk, hosted by Mary Beth Conley & Alex Coleman
April 28, 2009 Featured investigator, Channel 3 Live at Nine show, Stargardt Disease and Low
Vision, hosted by Mary Beth Conley & Alex Coleman
May 7, 2009 Invited Moderator, ARVO 2009 Retinal Dystrophies II poster session, RE and BI
sections, Ft. Lauderdale, FL May 5, 2010 Invited Moderator, ARVO 2010 Retinitis Pigmentosa poster session, BI section, Ft.
Lauderdale, FL
2010 Contributor, The Retinal Atlas, L.A. Yannuzzi, Editor (provided illustrations and
synopsis of several cases with rare diseases for the atlas). Aug. 2014 Featured Investigator, Memphis Medical News, Memphis on the Mend, “FFB Driving
the Research to Fight Blindness”, by Pamela Harris, Marketing Publisher, p. 7, Aug.
2014 issue.
Aug. 2014 Featured Investigator, UTHSC Campus Faculty News http://news.uthsc.edu/dr-alessandro-iannaccone-invited-to-write-editorial-in-lancet-to-
Pharmacy Board Researcher License, State of TN Dept of Health, No. 10960
(issued: Nov. 2014 – Dec. 2015) – for use of controlled substances/anesthetics with animals Board Certification: Eligible for certification by the American Board of Ophthalmology (ABO) under the new
Internationally Trained Ophthalmologist (ITO) track (as of Nov. 2014) with unrestricted MD license
SOCIETY MEMBERSHIPS: International Societies:
1992 – present Association for Research in Vision and Ophthalmology (ARVO)
1994 – present International Society for Clinical Electrophysiology of Vision (ISCEV)
1997 – present American Academy of Ophthalmology (AAO)
1997 – 2008 International Society for Eye Research (ISER)
1998 – 2003 American Association for the Advancement of Science (AAAS)
1999 – present International Society for Genetic Eye Disease and Retinoblastoma (ISGEDR)
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 7 of 35
National and Local Societies and Groups:
1990 – present Italian Society of Ophthalmology (SOI)
1990 – 2000 Italian Professional Association of Ophthalmologists (APIMO - merged with SOI
under the new acronym SOI-AMOI as of 2001)
1995 – 2001 Italian Society of Pediatric Ophthalmology (SIOP)
1997 – 2015 Memphis Eye Society, Honorary Member
2001 – present Downtown Memphis Lions Club Member
2003 – 2105 Tennessee Academy of Ophthalmology
2004 – present Research to Prevent Blindness Ophthalmological Associate
2007 – present Member-At-Large, Order of the Sons of Italy Association (OSIA)
2008 – present Fight For Sight Alumni Society TEACHING AND MENTORING EXPERIENCE: 1. June 97 – Aug. 97 Mentor, Courtney Carson, High School Student UT Summer Program. 2.
1998 – 2002 Lecturer, Module 4 of Ophthalmology, UT Medical Students 3. 1998 – Dec. 2003 Lecturer, Visual Electrophysiology and Psychophysics, Retinal Anatomy and Physiology,
Ophthalmic Genetics, Retinal Degenerations, UT Ophthalmology Residency Program 4. June 98 – Aug. 98Mentor, W. Brad Rouse, High School Student UT Summer Program. 5. June 99 – July 99Co-Mentor, Tara M. Feyen, High School Student UT Summer Program.
Co-Mentor, Richard McCluney, Pre-Med College Student (Wake Forest, NC)
6. May 00 – July 00Mentor, Richard McCluney, B.S., Pre-Medical School Student UTHSC, Memphis 7. May 00 – July 00Mentor, Ryan Robertson, High School Student, Memphis Challenge Program. 8. May 00 – July 00Mentor, Dewonia King, Christian Brothers University, UT Minority Opportunity Student
Program. 9. Aug. 00 – Dec. 00Mentor, Tim A. Parker, B.S., Southern College of Optometry student, Memphis, TN. 10. Nov. 01 – Jan. 02Mentor, Salvatore A. Tedesco, M.D., Visiting Ophthalmologist, University of Parma,
Department of Ophthalmology, Parma, Italy. 11. May 02 – July 02 Mentor, W. Andrew Todd, Tennessee Tech College Student, UT Summer College
Student Program
12. June 02 – Aug. 02 Mentor, Eduardo Maria Normando, B.S., Visiting Medical School Student, Campus
Biomedico University, Rome, Italy. 13. July 02 – June 03Mentor, Sara Saquib, M.D., Senior Research Assistant (Pakistan) 14. Jan. 03 – Sept. 04Thesis Committee Member, Songmei Meng, B.S. student, Masters of Science in
Epidemiology candidate, Univ. Tennessee College of Graduate Health Sciences, Memphis, TN.
15. May 03 – Aug. 03 Co-mentor, Lauren Mommsen (student at Arkansas State University, AR), Summer
College Student Program / McNair Program.
16. May 03 – Aug. 03 Co-mentor, Melissa Nelson (student at Central High School, Memphis, TN), Memphis
Challenge Student Program. 17. July 03 – June 04Mentor, W. Andrew Todd, B.S., Senior Research Assistant on ARMA Study. 18. Aug. 03 – Aug. 04Mentor, Basil Paulus, M.D., pre-residency intern and ophthalmology residency prospect. 19. Sept. 02 – Mar. 03Mentor, Salwa Ahmed, M.D., Senior Research Assistant on ARMA Study (Sudanese
ophthalmologist).
20. Jan. 04 – June 04 Mentor, Marco Mura, M.D., Research Scholar. 2nd
-year resident in Ophthalmology from
the University of Cagliari, Italy. 21. Feb. 04 – Dec. 15 Lecturer, Retinal Degenerations, Genetics & Epidemiology Series, Visual Electrophysiology
and Psychophysics, Retinal Anatomy and Physiology, Ophthalmic
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 8 of 35
Genetics, Retinal Degenerations, Basic Concepts of Biostatistics & Epidemiology, UT Ophthalmology Residency Program
22. April 04 – June 05Mentor, Jake P. Bostrom (M-3 Med School student, UTHSC, Memphis, TN). 23. June 04 – Dec. 06Mentor, Kevin Gallaher (Med School student, UTHSC, M-2 through M-4, Memphis, TN)
NIH Medical Student Research Fellowship Program, Stephen Tom, program coordinator. 24. June 04 – Aug. 04 Mentor, Tarsha L. Harris (senior student at Tougaloo College, Tougaloo, MS)
Summer College Student Program / McNair Program. 25. Jan. 06 – Dec. 15Mentor, Barbara J. Jennings, MA, OD (Research Scholar) 26. June 06 – Aug. 06Co-Mentor, Priya Sahu (Med School student, UTHSC, M-2) NIH Medical Student
Research Fellowship Program. 27. Jan. 07 – Dec. 07 Mentor, April M. Deaton-Cantrell, BS, COA – Winner of the 2007 Harold Stein Prize for
Best Scientific Paper from the Joint Commission of Allied Health Personnel in
Ophthalmology (JCAHPO) – sole winner, nationwide competition. 28. Jan. 07 – May 08Mentor, Jeremy T. Armstrong, Christian Brothers University. 29. Mar. 07 – Dec. 07Mentor, Lucas Romine (Med School student, UTHSC, M-3/4). 30. Oct. 07 – June 08Mentor, Lewis C. (“Cort”) Sommerville, MD, graduate of UTHSC Medical School. 31. Oct. 07 – Dec. 08Mentor, Monica Lynch (Med School student, UTHSC, M-3). 32. Jan. 08 – July 08Mentor, Denil Shekhat (Med School student, UTHSC, M-3). 33. Jan. 08 – Dec. 08Mentor, Ashley Laing (Med School student, UTHSC, M-3). 34. Jan. 08 – Jul. 2011 Mentor, Siva S. Radhakrishnan-Iyer, MD (resident, UTHSC Ophthalmology) – Winner of
best poster in clinical case series category and best poster overall of the Tennessee
Medical Association Residents and Fellows Meeting, Nashville, TN, April 11, 2009. 35. Jan. 09 – Sep. 2010 Mentor, Giovannella Carboni, MD (Research Scholar, UTHSC Ophthalmology) –
Awarded funding for a Masters & Back post-residency training program financed by the
45. Mar. 12 – May 13 Co-Mentor, Kyle Cox (Med School student, UTHSC, Memphis, TN).
46. Mar. 12 – June 13 Co-Mentor, Ophthalmology Residents and Fellows –Drs. Calderwood, Kosko, Wilkin, and
and Huddleston (residents) and Dr. Aladdin Rashwani (fellow).
47. Jan. – Dec. 2013 Mentor, Albert H. Alhatem, MD (postdoctoral fellow) – Winner of 2014 ARVO Informa
Healthcare Travel Award.
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 9 of 35
48. Jan. 2013 – May 2015 Mentor, David D. New, PhD (postdoctoral fellow) –Winner of UTHSC Postdoc Association
Travel Award and 2014 ARVO C. Stephen and Frances B. Foster Foundation Travel
Award.
49. May – July 2013 Co-Mentor, Louise LaFlora (Med School student, Meharry University, Nashville, TN, with
Dr. Natalie Kerr, MD, FACS).
50. May 2013 – Aug. 2016 Mentor, Eric Sollenberger (Med School student, UTHSC, Memphis, TN) NIH Medical
Student Research Fellowship Program recipient.
51. May 2013 – Aug. 2016 Mentor, Rebecca S. Epstein, MD (Ophthalmology resident, UTHSC, Memphis, TN). AAO
poster received the highest grades within its subject area by the AAO Program Cmte.
52. Mar. – Aug. 2014 Co-Mentor, Justin Wilkin, MD (Ophthalmology senior resident, UTHSC, Memphis, TN,
with Dr. Natalie Kerr, MD, FACS).
53. Mar. – Aug. 2014 Mentor, Michael Hood, MD (Ophthalmology senior resident, UTHSC, Memphis, TN). 54. May 2014 – June 2015Mentor, T.J. Hollingsworth, PhD (postdoctoral fellow). 55. Aug. 2014 – Mar. 2015Co-Mentor, Joshua Barnett, PhD (M4 Med Student, with Dr. Natalie Kerr, MD, FACS,
accepted in Ophthalmology Residency at Vanderbilt) – Won Best Poster Award for
the Retina Section at the 2015 AAPOS Meeting. 56. Apr. 2015 – Mar. 2016Mentor, Rutviben Patel, BS (raising M4 Med Student, UTHSC, Memphis, TN). 57. Apr. 2015 – Mar. 2016Mentor, Cole Smith, BS (M4 Med Student, UTHSC, Memphis, TN). 58. June 2015 – presentMentor, Salar Rafieetary, BS (M4 Med Student, UTHSC, Memphis, TN). 59. Oct. 2016 – presentLecturer, Retinal Degenerations and Ophthalmic Genetics, Visual Electrophysiology and
Psychophysics, Retinal Anatomy and Physiology, Ophthalmic Genetics, Retinal Degenerations, Duke Eye Center Residency Program
INVITED LECTURES AND PRESENTATIONS:
1. July 27, 1993 Invited Speaker, Three-year experience in the treatment of retinitis pigmentosa with thymopentin. Dr. Eliot L. Berson, host, Berman-Gund Laboratory, Massachusetts Eye & Ear
Infirmary, Boston, MA
2. May 28, 1996 Invited Speaker, Visual function tests as an aid to the diagnosis and characterization of
retinal disorders. Dr. Richard S. Ruiz, host, Department of Ophthalmology, University of
Texas-Houston Health Science Center, Houston, TX
3. July 11, 1996 Invited Speaker, Visual function tests as an aid to diagnosis and characterization of retinal diseases. Dr. David G. Birch, host, Anderson Vision Research Center, Retina Foundation
of the Southwest, Dallas, TX
4. April 23, 1998 Invited Speaker, Update on hereditary retinal degenerations. Prof. Riccardo Neuschüler,
host, Division of Ophthalmology, Fatenebenefratelli Hospital, Isola Tiberina, Rome, Italy
5. Dec. 5, 1998 Invited Speaker, The Newly Established Retinal Degeneration Referral Center at the University of Tennessee. Louis Dawson, host, President, Foundation Fighting Blindness
Arkansas Affiliate Meeting, Jacksonville, AR
6. Feb. 4, 1999 Invited Speaker, The Newly Established Retinal Degeneration Referral Center at the University of Tennessee. Don Morris, Ed.D., host, Program Director. Alliance for the Blind
and Visually Impaired, Memphis, TN
7. Feb. 26, 1999 Invited Speaker, Genotype-phenotype correlations in macular degenerations. Prof. Luigi Scullica and Dr. Benedetto Falsini, hosts, Ophthalmic Education Course, Macular Degeneration: A Multidisciplinary Approach. Institute of Ophthalmology, Catholic University
of the Sacred Heart, Rome, Italy
8. March 19, 1999 Invited Speaker, Abnormalities of visual evoked potentials in children with neurofibromatosis type 1: preliminary findings. Dr. June Taylor, organizer, St. Jude
Children’s Research Hospital, Memphis, TN
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 10 of 35
9. March 26, 1999 Invited Speaker, The importance of Genotype-Phenotype Correlations in Hereditary
Retinal Diseases. Dr. Dianna Johnson, host, 1999 UT Memphis Vision Research
Symposium Molecular Biology/Molecular Genetics of the Visual System, University of
Tennessee, Coleman Building, South Auditorium, Memphis, TN 10. April 29, 1999 Invited Speaker, The Newly Established Retinal Degeneration Referral Center at the
University of Tennessee. Ms. Mildred Sessions, Host, Ascension Towers Retirement
Community, Memphis, TN 11. Sept. 19, 1999 Invited Speaker, Overview of Research at the Newly Established Retinal Degeneration
Referral Center at the University of Tennessee, Ms. Susan Freeze, host (lay audience)
Middle Tennessee Foundation Fighting Blindness Affiliate, Nashville, TN 12. Dec. 16, 1999 Invited Speaker, Allelic heterogeneity in autosomal dominant retinitis pigmentosa due to
different rhodopsin mutations: Clues from electroretinogram measurements Dr. William J. Kimberling, host, Center for Hereditary Communication Disorders,
Boys Town National Research Hospital, Omaha, NE 13. March 7, 2000 Invited Speaker, Genotype-phenotype correlations in autosomal dominant retinitis pigmentosa
due to rhodopsin mutations. Prof. Scullica and Neri, hosts, Ophthalmic Education Course,
Retinitis Pigmentosa: From Animal Models to Human Disease. Institute of Ophthalmology,
Catholic University of the Sacred Heart, Rome, Italy 14. June 2, 2001 Invited Speaker, X-linked Juvenile Retinoschisis. Elias Traboulsi, M.D., Jonathan Sears, M.D.,
and Joe Hollyfield, Ph.D., Co-directors, Ophthalmic Education Course, Pediatric and
Inherited Retinal diseases. Cole Eye Institute, The Cleveland Clinic, Cleveland, OH 15. Aug. 31, 2001 Invited Speaker, X- linked Juvenile Retinoschisis, Paul R. Lichter, M.D., host, W.K. Kellogg Eye
Center, Univ. of Michigan, Ann Arbor, MI 16. Feb. 19, 2002 Invited Speaker, Clinical and Functional Studies of X-linked Juvenile Retinoschisis
Paul A. Sieving, M.D., Ph.D., host, National Eye Institute, NIH, Bethesda, MD 17. April 15-16, 2002 Panel Speaker, Clinical Trials for Retinal Degenerative Diseases: Bridging the Efforts Across
Continents. Session II: Is Phenotype a Predictable and Useful Criteria for Patient
Selection? and Session III: Recruitment Resources: Mechanisms to Enroll the Appropriate
du Luxembourg, Paris, France 18. May 20, 2002 Invited Speaker, X-linked Retinoschisis: Clinical, Functional, and Differential Diagnostic
Aspects. Mark Sherwood, M.D., host, Dept. Ophthalmology, Univ. Florida, Gainesville, FL 19. Sept. 12, 2002 Invited Speaker, The Health ABC Age-Related Maculopathy Ancillary (ARMA) Study
Julie Mares-Perlman, Ph.D., host, Dept. of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI
20. Sept. 28, 2002 Invited Speaker, Present and Future of Genotypic and Phenotypic Studies in Hereditary
Retinal Degenerations, Claudio Macaluso, M.D., and Salvatore Tedesco, M.D., Co-
organizers, Ophthalmic Education Course, Hereditary Retinal Degenerations: From
Genetics to Clinical Manifestations. Dept. of Ophthalmology, University of Parma, Italy 21. Feb. 7/9, 2003 Invited Speaker, Usher syndrome. Broadcast radio interview on Eye on Vision, Vance
Durbin, host, WYPL Tennessee Public Library Radio (89.3 FM) 22. Feb. 21/23, 2003 Invited Speaker, Stargardt disease. Broadcast radio interview on Eye on Vision, Vance
Durbin, host, WYPL Tennessee Public Library Radio (89.3 FM) 23. April 3, 2003 Invited Speaker, The Health ABC Age-Related Maculopathy Ancillary (ARMA) Study,
Stephen B. Kritchevsky, Ph.D., host, UTHSC Dept. of Preventive Medicine, Health ABC Appreciation Day, Lindenwood Christian Church Auditorium, Memphis, TN
24. May 23/25, 2003 Invited Speaker, Best’s disease. Broadcast radio interview on Eye on Vision, Vance
Durbin, host, WYPL Tennessee Public Library Radio (89.3 FM) 25. July 4/6, 2003 Invited Speaker, Leber’s Congenital Amaurosis. Broadcast radio interview on Eye on
Vision, Vance Durbin, host, WYPL Tennessee Public Library Radio (89.3 FM)
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 11 of 35
26. Feb. 12, 2004 Invited Speaker, The Health ABC Age-Related Maculopathy Ancillary (ARMA) Study Council on Aging, Memphis, TN
27. April 20, 2004 Invited Speaker, The Health ABC Age-Related Maculopathy Ancillary (ARMA) Study
The Parkview Retirement Community, Memphis, TN (lay audience) 28. May 4, 2004 Invited Speaker, The Health ABC Age-Related Maculopathy Ancillary (ARMA) Study
St. Peter’s Manor Retirement Community, Memphis, TN (lay audience) 29. June 15, 2004 Invited Speaker, Epidemiology of Age-Related Vision Problems in the U.S. and in Tennessee,
Susanne Satterfield, M.D., host, UTHSC Dept. of Preventive Medicine, Health ABC
Appreciation Day, Lindenwood Christian Church Auditorium, Memphis, TN 30. Dec. 10, 2004 Invited Speaker, Macular Pigment Densitometry in the Elderly: A Promising Tool for Age-
Related Maculopathy Research , Distinguished Visiting Lecture, Sandra B. Blackwood,
Director, IRRF, and Lanning B. Kline, M.D., Chairman, UAB Dept. of Ophthalmology,
hosts, Callahan Eye Foundation Hospital, Smith Education Center, Birmingham, AL 31. Dec. 10, 2004 Invited Speaker, A Clinical, Diagnostic, and Genetic Overview of Hereditary Retinal Diseases,
Lanning B. Kline, M.D., Chairman, UAB Dept. of Ophthalmology, host, Callahan Eye
Foundation Hospital, John E. Meyer Library, Birmingham, AL 32. Dec. 15, 2004 Invited Speaker, RPGR Mutations Cause X-linked Pseudo-Usher Syndrome: A Clinical and
Immunohistochemical Study, J. Fielding Hejtmancik, M.D., Ph.D., host, National Eye
Institute, NIH, Cogan Library, Bethesda, MD 33. Jan. 7/21, 2006 Invited Speaker, Retinoschisis. Broadcast radio interview on Eye on Vision, Vance Durbin,
host, WYPL Tennessee Public Library Radio (89.3 FM) 34. April 8/29, 2006 Invited Speaker, Carotenoids and Age-Related Macular Degeneration. Radio interview on
Eye on Vision, Vance Durbin, host, WYPL Tenn. Public Library Radio (89.3 FM) 35. Oct. 5, 2006 Invited Speaker, Longitudinal Measurements of Visual Function in Usher Syndrome Type II,
First International Symposium on Usher Syndrome and Related Disorders, Dr. William
J. Kimberling and Dr. Claes Möller, co-organizers, Boys Town National Research
Hospital, Omaha, NE 36. April 7/21, 2007 Invited Speaker , The Foundation Fighting Blindness Mid -South Chapter. Broadcast radio
interview on Eye on Vision, V. Durbin, host, WYPL Tenn. Public Library Radio (89.3 FM) 37. May 19, 2007 Guest Speaker, Scientific Advances: A Cure is in Sight, UTHSC Hamilton Eye Institute,
Freeman Auditorium, J. David and Charlene Spiceland, Co-Presidents and hosts,
1st Foundation Fighting Blindness Mid-South Chapter of Memphis meeting,
Memphis, TN 38. July 20-21, 2007Invited Speaker, VISIONS2007, The Foundation Fighting Blindness, Kansas City, KC. 39. Dec. 4, 2007Invited Speaker, Clinical Research in Ophthalmology: Developing a Career As A Physician
Scientist Student Interest Group in Ophthalmology (SIGIO), Freeman Auditorium, UTHSC Hamilton Eye Institute, Memphis, TN
40. June 7, 2008 Guest Speaker, The Latest in Gene Therapy: Clinical Research Information You Won ’t Want
to Miss, UTHSC Hamilton Eye Institute, Freeman Auditorium, Foundation Fighting
Blindness Mid-South Chapter of Memphis meeting, Memphis, TN 41. Sept. 2, 2008 Invited Speaker, Multidisciplinary Approaches To Retinal Degenerations, UIC Department of
Ophthalmology & Visual Science, Gerald Fishman, MD, host, Chicago, IL 42. Oct. 4, 2008 Invited Speaker, Update on Gene Therapy for Leber’s Congenital Amaurosis, the Memphis
Vision Seminar and VisionWalk. Broadcast radio interview on Eye on Vision, V. Durbin,
host, WYPL Tenn. Public Library Radio (89.3 FM) 43. Oct. 11, 2008 Guest Speaker, 1. Genetics and Inheritance of Retinal Degenerative Diseases. 2. Retinitis
Pigmentosa and Other Inherited Diseases, Foundation Fighting Blindness’ Memphis
Vision Seminar, Fogelman Auditorium, University of Memphis, Memphis, TN
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 12 of 35
MD, Chair, host, Louisiana State University Eye Center, LSUHSC, New Orleans, LA 52. Dec. 30, 2014 Invited Speaker, Update on the role of inflammation and autoimmunity in age -related macular
degeneration. Broadcast radio interview on Eye on Vision, V. Durbin, host, WYPL Tenn.
Public Library Radio (89.3 FM) 53. Apr. 23, 2015 Invited Speaker, Understanding the Role of Autoimmunity in Age-Related Macular
Degeneration. David Gamm, MD, PhD, Director, McPherson Eye Research Institute,
host, Univ. Wisconsin, Madison, WI 54. Apr. 24, 2015 Invited Speaker, The Overlapping Worlds of Hereditary Retinal Degenerations and
Autoimmune Retinopathy: RP Phenocopies and Immune-Mediated Complications of
Univ. Wisconsin, Madison, WI 55. April 28, 2015 Invited Speaker, Characterizing the role of autoimmunity in retinal degenerative diseases: Well
beyond simple disease biomarkers. Mechanistic commonalities between retinitis
pigmentosa, primary autoimmune retinopathies, and age-related macular degeneration. Jayne Weiss, MD, Chair, host, LSU Eye Center, LSUHSC, New Orleans, LA
56. May 11, 2015 Invited Speaker, Translational Studies of Inflammation and Autoimmunity in Age-Related
Macular Degeneration. Clivel Charlton, PhD, Chair, host, Dept. of Neuroscience and
Pharmacology, Meharry Medical College, Nashville, TN 57. May 14, 2015 Invited Speaker, The different facets of night blindness: Why phenotyping and genotyping both
matter. Douglas Lazzaro, MD, FACS, Chair, host, SUNY-Downstate, Department of
Ophthalmology, Brooklyn, NY 58. June 12, 2015 Invited Speaker, The Overlapping Worlds of Hereditary Retinal Degenerations and
Autoimmune Retinopathy. Nick Volpe, MD, Professor and Chair, Northwestern
University, Department of Ophthalmology & Visual Sciences, Chicago, IL 58. Aug. 10, 2015 Invited Speaker, Characterizing the role of autoimmunity in retinal degenerative diseases: Well
beyond simple disease biomarkers Todd Margolis, MD, PhD, Professor and Chairman,
host, Washington University, Dept. Ophthalmol. & Vis. Sci., St. Louis, MO 60. Dec. 1, 2015 Invited Speaker, Translational Studies on the Role of Autoimmunity in Age -Related Macular
Degeneration, Donald L. Budenz, MD, MPH, Professor and Chair, host, University of
North Carolina, Kittner Eye Center, Chapel Hill, NC
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 13 of 35
61. Jan. 5, 2016 Invited Speaker, The Overlapping Worlds of Hereditary Retinal Degenerations and
Autoimmune Retinopathy: RP Phenocopies and Immune-Mediated Complications of
Retinal Dystrophies. Grand Rounds presentation. Sonal Tuli, MD, Professor and
Chair, host. Dept. Ophthalmology, Univ. Florida, Gainesville, FL 62. Jan. 5, 2016 Invited Speaker, Translational Studies on the Role of Autoimmunity in Age-Related Macular
Degeneration. William Hauswirth, PhD, Professor and Director of Research, host. Dept.
Ophthalmology, Univ. Florida, Gainesville, FL 63. Jan. 13, 2016 Invited Speaker, Characterizing the role of autoimmunity in retinal degenerative diseases: Well
beyond simple disease biomarkers. Craig Greven, MD, Professor and Chair, Wake Forest
Dept. of Ophthalmology, Winston-Salem, NC 64. Feb. 2, 2016 Invited Speaker, Clinical and translational studies of retinal aging and degenerative
diseases – Relevance to interracial differences in health, pathology and response to treatment. Duane Smoot, MD, Professor, host. Meharry Translational Research Center (MeTRC), Meharry Medical College, Nashville, TN
COMMITTEES AND OFFICES HELD: Committees and Miscellanea 1998 - 1999 Member, 1999 Vision Research Symposium Organizing Committee, UT Vision
Research Center
1999 - 2002 Ad-Hoc Grant Reviewer, Foundation Fighting Blindness, Columbia, MD
June 7, 2002 Co-Honorary Chair (with Monica M. Jablonski, PhD), Give the Gifts X, 10th
Blindness, Overton Park, Memphis, TN, October 18, 2009
June – July 2009 Member, NIH ZRG1 CB-N (58) RC1 Grant Review Committee, Center for Scientific
Oct. 2009 – July 2015 Review Special Emphasis Panel Coordinator, Ophthalmology Game Coverage, Memphis Grizzlies, National Basketball
Association (NBA), Memphis, TN, Drew Graham, Head Athletic Trainer and Vice President
of Player Care
Mar. – April 2010 Ad-Hoc Grant Reviewer, University of Michigan Pilot Grant Program in Aging Research, University of Michigan's Claude Pepper Older Americans Independence Center, Nathan Shock Center of Excellence in Aging Research, and Michigan Institute for Clinical & Health
Research, Ann Arbor, MI
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 14 of 35
Mar. 2010 - present Editorial Board Member, Society for Clinical Ophthalmology
Memphis VisionWalk, Foundation Fighting Blindness, Overton Park, Memphis, TN, October 22, 2011
Feb. – Dec. 2011 Co-President, Foundation Fighting Blindness Mid-South Chapter of Memphis Aug. 2-3, 2011 Member, NEI R01/R13/R21 ZEY1 VSN (02) Grant Review Committee, National Eye
Institute Special Emphasis Panel Jan. 2012 Reviewer, Choroideremia Research Foundation, Springfield, MA
Memphis VisionWalk, Foundation Fighting Blindness, Patriot Lake at Shelby Farms, Memphis, TN, October 25, 2014
June 2014 - present Scientific Advisory Board Member, Choroideremia Research Foundation, Inc.,
Springfield, MA (invited as inaugural SAB member by Chris Moen, MD, President) Sept. 2014 - present Scientific Advisory Board Member, Blue Cone Monochromacy Families Foundation,
Jupiter, FL (invited as inaugural SAB member by Renata Sarno, PhD, President)
May 2015 - 2018 Appointed Member, Advocacy and Outreach Committee (AOC), Association for
Research in Vision and Ophthalmology (ARVO) – 3-year term March – April 2016 Member, NIH ZEY1 VSN 01, National Eye Institute Study Section
Journal Review Assignments Retina, Ophthalmic Genetics, British Journal of Ophthalmology, Documenta Ophthalmologica, Investigative
Ophthalmology and Visual Science (2002, Guest Editorial Board member), American Journal of Ophthalmology,
Eye , Molecular Vision, Journal of Medical Genetics, Comprehensive Ophthalmology Update, Hospital Physician and American Journal of Clinical Nutrition, Canadian Journal of Ophthalmology, Experimental Eye Research,
Archives of Ophthalmology/JAMA Ophthalmology, Current Eye Research, Retina Cases & Brief Reports, Cancers, Human Molecular Genetics, Human Gene Therapy, Translational Vision Science & Technology, Biology
Role: PI until 12/31/15, Unpaid Consultant 1/16 – 8/16, Co-PI status activation pending
BrightFocus Foundation Macular Degeneration Giorgianni (PI) 7/16 - 6/18
Research Program, Clarksburg, MD In vitro and in vivo studies of CD5L/AIM as a possible key role player in drusen biogenesis Role: Co-Investigator, subcontract activation pending
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 15 of 35
Pending Support (includes recently submitted grants, grants awaiting resubmission, or established contacts with companies to
conduct clinical studies or trials as Site PI prior to 12/31/15, all start dates tentative pending relocation)
R01 EY026577, NEI/NIH Giorgianni (PI) 7/17 - 06/22 Translational investigations of CD5L/AIM in age-related macular degeneration
Role: Co-PI (MPI application)
FDA Office of Orphan Product Development Duncan (PI) 05/17 - 04/22 Rate of Progression in USH2A Related Retinal Degeneration (RUSH2A)
Role: Site PI (Multicenter Natural History Study)
Shire Human Genetic Therapies Iannaccone (Site PI) 1/17 - 12/21
Lexington, MA A Prospective, Multi-center, Longitudinal, Observational Natural History Study to Evaluate Disease Progression in
Subjects with Autosomal Dominant Retinitis Pigmentosa (adRP) with Misfolded Rod Opsin Mutations (SHP630-001)
X-linked retinoschisis: A multi-center Phase I gene therapy trial (RS1-001)
Ionis Pharmaceuticals, Inc./Emmes Corp. Iannaccone (Site PI) 09/16 - 12/17 Retinitis Pigmentosa Natural History Study of Patients with the P23H Mutation
(Continuation of study I was already previously conducting at UTHSC)
Biotech company (TBD) Iannaccone (Site PI) TBD
Choroideremia: A multi-center Phase I gene therapy trial
Completed Research Projects (in chronological order, earliest to most recent, since 2001, highlighted in bold are the most significant ones)
International Retinal Research Iannaccone (PI) 04/02 - 12/07
Foundation, Inc., Birmingham, AL
Epidemiology of Carotenoids, Inflammation, and Genetic Markers in Age-Related Macular Degeneration
Research to Prevent Blindness, Inc. Iannaccone (PI) 01/03 - 12/07
New York, NY
Research to Prevent Blindness Career Development Award
Bhoeringer-Ingelheim (Ronald J. Pfeiffer, M.D. 04/07 - 05/09
(contract, multi-center Phase IV study) UTHSC Neurology, PI)
A Two-Year Open Label, Randomized, Parallel Group, Blinded Assessment Ophthalmologic Safety Study of Parkinson Disease Treatments (BIPI Trial 248.538)
Role: Subcontractor
Neurotech USA CNTF3 Trial Iannaccone (Site PI) 04/07 - 05/09
(Contract, multi-center Phase II/III study) A phase II/III study using a new experimental treatment for participants with retinitis pigmentosa using visual
acuity as the primary outcome
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 16 of 35
Neurotech USA CNTF4 Trial Iannaccone (Site PI) 04/07 - 05/10
(Contract, multi-center Phase II/III study) A phase II/III study using a new experimental treatment for participants with retinitis pigmentosa using visual
field sensitivity as the primary outcome
National Neurovision Research Institute Iannaccone (Site PI) 04/07 - 03/08
Foundation Fighting Blindness, Owing Mills, MD
Infrastructural Support for CNTF Trials
Hamilton Eye Institute Intramural Funding Iannaccone (PI) 04/07 - 03/08
Infrastructural Support for CNTF Trials
International Retinal Research Iannaccone (PI) 01/08 - 12/10
Foundation, Inc., Birmingham, AL
Autoimmune Biomarkers of Age-Related Macular Degeneration
Pfizer Adamolekun (Site PI) 01/08 - 12/10 Prospective Randomized, 12-Week Controlled Study of Visual Field Change in Subjects with Partial Seizures Receiving Active Treatment or Placebo Role: Subcontractor
Zeavision, St Louis, MO Iannaccone (PI) 01/09 - 12/10
Age-Related Eye Disease Study 2 (AREDS2) Clinical Center Award
Role: 6/07 – 04/13, Site Co-Investigator (5/06 – 5/07, Site PI)
NEI/NIH, and Notal Vision, Ltd Chaum (Site PI) 06/10 - 04/13 Home Vision Monitoring in AREDS2 for Progression to Neovascular AMD Using the Foresee Home Device Role: Site Co-Investigator
Prana Biotechnology, Ltd. Ray Dorsey (PI) 6/12 – 6/13 Parkville, Australia Johns Hopkins
Reach2HD – A Huntington’s Disease Clinical Research Trial
Role: Co-Investigator (M. LeDoux, UTHSC Neurology, Site PI)
Research to Prevent Blindness Iannaccone (PI) 07/12 - 06/15
Physician Scientist Award
New York, NY
UT Pharmaceutical Sciences Giorgianni (PI) 09/13 - 08/14
Intramural Pilot Project UT Pharmaceutical Sciences
Identification of Autoimmunity Antigens in Age-Related Macular Degeneration Role: Co-Investigator
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 17 of 35
Foundation Fighting Blindness Iannaccone (Site PI) 11/11 - 12/15 Clinical Research Institute,
Columbia, MD
(formerly known as National Neurovision Research Institute) A Phase II Multiple Site, Randomized, Placebo-Controlled Trial of Oral Valproic Acid
for Retinitis Pigmentosa #H-13371 Dennis & Laura Gierhart Charitable Fund Iannaccone (PI) 04/09 - 12/15 Macular Pigment Optical Density: Functional Correlates Before and After Augmentation by An Open-Label, Short-
Term Pilot Dietary Supplementation with Zeaxanthin (ZEASTRESS-Pilot)
Ionis Pharmaceuticals, Inc./Emmes Corp. Iannaccone (site PI) 12/14-12/15 Retinitis Pigmentosa Natural History Study of Patients with the P23H Mutation of the Rhodopsin
Gene (RHONHS)
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 18 of 35
BIBLIOGRAPHY
Manuscripts Published on International Peer-Reviewed Journals
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Luleci G, Iannaccone A, Jacobson SG, Weleber RG, Wright AF, Riise R, Hennekam RCM, Biesecker LG,
Stone EM, Sheffield VC. Evaluation of complex inheritance involving the most common Bardet-Biedl
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the Enhanced S-Cone Syndrome reveals a lack of sequence variations in the NRL gene. Mol. Vis. 2003; 9:
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36. Iannaccone A, Kritchevsky SB, Ciccarelli ML, Tedesco SA, Macaluso C, Kimberling WJ, Somes G. Kinetics of
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38. Gruber M, Chappell R, Millen A, LaRowe T, Moeller SM, Iannaccone A, Kritchevsky SB, Mares J.
Correlates of serum lutein + zeaxanthin: Findings from the Third National Health and Nutrition Examination
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decreased olfaction in Bardet-Biedl syndrome caused by a deletion in the BBS4 gene. Am. J. Med. Genet.
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Update 2005; 6: 39-62 (invited review)
42. Wang XF, Iannaccone A, Jablonski MM. Contribution of Müller cells toward the regulation of
43. Iannaccone, A, Mura, M, Dyka, FM, Ciccarelli, ML, Yashar, BM, Ayyagari, R, Jablonski, MM, Molday, RS. An
unusual X-linked retinoschisis phenotype and biochemical characterization of the W112C RS1 mutation.
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Bush RA, Salem Jr N, Sieving PA, Ayyagari R. Elovl4 5bp-deletion knock-in mice develop progressive
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Johnson KC, Kritchevsky SB for the Health ABC Study. Macular pigment optical density in the elderly.
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48. Gallaher KT, Mura M, Todd WA, Harris TL, Kenyon E, Harris T, Johnson KC, Satterfield S, Kritchevsky SB,
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in families with X-linked ocular albinism. Mol. Vis. 2007; 13:1856-61. PMID: 17960122
52. Iannaccone A, Othman MI, Cantrell AD, Jennings BJ, Branham K, Swaroop A. Retinal phenotype of an X-
linked pseudo-Usher syndrome in association with the G173R mutation in the RPGR gene. Adv. Exp.
Med. Biol. 2008; 613: 221-227. PMID 18188948 53. Miyake N, Chilton J, Psatha M, Cheng L, Andrews C, Chan W-M, Law K, Crosier M, Lindsay S, Cheung M,
Allen J, Gutowski NJ, Ellard S, Young E, Iannaccone A, Appukuttan B, Stout JT, Christiansen S, Ciccarelli
ML, Baldi A, Campioni M, Zenteno JC, Mariani LE, Sahin M, Guthrie S, Engle EC. Human CHN1
mutations hyperactivate a2-chimaerin and cause Duane’s Retraction Syndrome. Science 2008; 321(5890): 839-43 (suppl. material online). PMID 18653847
54. Iannaccone A, Fung KH, Eyestone ME, Stone EM. Treatment of Adult-Onset Acute Macular Retinoschisis
in Enhanced-S Cone Syndrome with Oral Acetazolamide. Am. J. Ophthalmol. 2009; 147(2): 307-312.e2
(suppl. material online). PMID 18835469 55. Philp AR, Jin M, Li S, Schindler EI, Iannaccone A, Lam BL, Weleber RG, Fishman GA, Jacobson SG, Mullins
R, Travis GH, Stone EM. Predicting the Pathogenicity of RPE65 Mutations. Human Mutation 2009;
30(8):1183-8. PMID 19431183
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 21 of 35
56. Iannaccone A*, Kerr NC*, Kinnick TR, Calzada JI, Stone EM. Autosomal Recessive Best's Vitelliform Macular
Dystrophy: Report of a Family and Management of Early-Onset Neovascular Complications. Arch.
Harris TB, Nalls MA, Kritchevsky SB, Newman AB, for the Health ABC Study. The Association of Cataract
With Leukocyte Telomere Length in Older Adults: Defining a New Marker of Aging. J Gerontol A Biol Sci Med Sci. 2011; 66(6): 639-45. PMID 21382885
58. Spencer KL, Olson LM, Schnetz-Boutaud N, Scott WK, Gallins P, Agarwal A, Pericak-Vance MA, Iannaccone A,
Kritchevsky SB, Garcia M, Kenyon E, Nalls M, Newman AB, Haines JL. Using Genetic Variation and Environmental
Risk Factor Data to Identify Individuals at High Risk for Age-Related Macular Degeneration. PLoS ONE 2011; 6(3):
e17784. doi:10.1371/journal.pone.0017784 (suppl. material online). PMID 21455292 59. Adamus G, Brown L, Schiffman J, Iannaccone A. Diversity in autoimmunity against retinal, neuronal and
axonal antigens in acquired neuro-retinopathy. J. Ophthal. Inflamm. Infect. 2011; 1(3): 111-21. Epub 2011
SL, Sumaroka A, Conlon TJ, Calcedo R, Pang J-J, Erger KE, Olivares MB, Mullins CL, Swider M, Kaushal S, Feuer WJ, Iannaccone A, Fishman GA, Stone EM, Byrne BJ, Hauswirth WW. Gene Therapy for Leber
Congenital Amaurosis caused by RPE65 mutations: Safety and Efficacy in Fifteen Children and Adults Followed up to Three Years. Arch Ophthalmol 2012; 130(1): 9-24 (suppl. material online). PMID 21911650
61. Iannaccone A, Neeli I, Krishnamurthy P, Lenchik N, Wan H, Gerling IC, Desiderio DM, Radic MZ.
Autoimmunity in Age-Related Macular Degeneration: A Possible Role Player in Disease Development
and Progression. Adv. Exp. Med. Biol. 2012; 723:11-6. PMID 22183309
62. De Falco M, Manente L, Lucariello A, Baldi G, Fiore P, Laforgia V, Baldi A, Iannaccone A, De Luca A.
Localization and distribution of wolframin in human tissues. Front. Biosci. (Elite Ed) 2012; E4 (5): 1986-98. PMID 22202014
63. Carboni G, Forma G, Bond AD, Adamus G, Iannaccone A. Bilateral paraneoplastic optic neuropathy in
association with prostate cancer and unilateral central retinal artery occlusion: A differential diagnostic
challenge in a patient with unexplained visual loss. Doc. Ophthalmol. 2012; 125(1): 63-70. PMID 22569848 64. Burke T, Fishman GA, Zernant J, Schubert C, Tsang SH, Smith RT, Ayyagari R, Koenekoop RK, Umfress A,
Ciccarelli ML, Baldi A, Iannaccone A, Cremers FP, Klaver CCV, Allikmets R. Retinal phenotypes in patients
homozygous for the G1961E mutation in the ABCA4 gene. Invest. Ophthalmol. Vis. Sci. 2012; 53(8): 4458-67. PMID: 22661473
65. Cox K, Kerr NC, Kedrov M, Nishimura D, Jennings BJ, Stone EM, Sheffield VC, Iannaccone A. Phenotypic
Expression of Bardet-Biedl Syndrome in Patients Homozygous for the Common M390R Mutation in the
Study Group*. Methods and Reproducibility of Grading Optimized Digital Color Fundus Photographs in the
Age-Related Eye Disease Study 2 (AREDS2 Report Number 2). Invest. Ophthalmol. Vis. Sci. 2013; 54(7):
4548-4554 (*member, see appendix to paper). PMID: 23620429 70. Birch DG, Weleber RG, Duncan JL, Jaffe GJ, Tao W; Ciliary Neurotrophic Factor Retinitis Pigmentosa
Study Groups*. Randomized trial of ciliary neurotrophic factor delivered by encapsulated cell intraocular
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 22 of 35
implants for retinitis pigmentosa. Am. J. Ophthalmol. 2013; 156(2): 283-292.e1. (*member, see appendix to paper). PMID: 23668681
71. Wang X, Wang H, Sun V, Tuan H-F, Keser V, Wang K, Ren H, Lopez I, Zaneveld E, Siddiqui S, Bowles S, Khan A, Wang F, Fishman GA, Iannaccone A, Salvo S, Birch DG, Heckenlively JR, Jacobson SG, Traboulsi
EI, Li Y, Koenekoop RK, Chen R. Comprehensive molecular diagnosis of 189 Leber congenital amaurosis
and juvenile retinitis pigmentosa patients by targeted next-generation sequencing and clinical re-visit. J. Med. Genet. 2013; 50(10): 674-88. PMID: 23847139
72. Vishwanathan R, Iannaccone A, Scott TM, Kritchevsky SB, Jennings BJ, Carboni G, Forma G, Satterfield S, Harris
T, Johnson KC, Schalch W, Renzi LM, Rosano C, Johnson EJ, for the Health ABC Study. Relationships Among
Macular Pigment and Cognition in the Elderly. Age Ageing 2014; 43(2): 271-5 (PMID: 24435852)
73. Lucariello A, Perna A, Sellitto C, Baldi A, Iannaccone A, Cobellis L, De Luca A, De Falco M. Modulation of
wolframin expression in human placenta during pregnancy: comparison among physiological and
pathological states. BioMed Res Int 2014; doi: 10.1155/2014/985478. PMID: 24588001) 74. Domalpally A, Danis RP, Chew EY, Clemons TE, Reed S, Sangiovanni JP, Ferris FL3rd, AREDS2 Study
Group*. Evaluation of optimized digital fundus reflex photographs for lens opacities in the age-related eye
disease study 2: AREDS2 report 7. Invest Ophthalmol Vis Sci 2013;54:5989-5994 (*member, see appendix
to paper) PMID 3771555 75. AREDS2-HOME Study Research Group*, Chew EY, Clemons TE, Bressler SB, Elman MJ, Danis RP,
Domalpally A, Heier JS, Kim JE, Garfinkel R. Randomized Trial of a Home Monitoring System for Early
Detection of Choroidal Neovascularization Home Monitoring of the Eye (HOME) Study. Ophthalmology
2014; 121(2): 535-44 (*member, see appendix to paper) PMID: 24211172 76. Jackson GR, Scott IU, Kim IK, Quillen DA, Iannaccone A, Edwards JG. Diagnostic Sensitivity and
Specificity of Dark Adaptometry for detection of Age-Related Macular Degeneration. Invest. Ophthalmol. Vis.
Sci. 2014; 55(3): 1427-31. PMID: 24550363 77. Chew EY, Clemons TE, Bressler SB, Elman MJ, Danis RP, Domalpally A, Heier J, Kim JE, Garfinkel R;
Appendix 1 for AREDS2-HOME Study Research Group*. Randomized trial of the ForeseeHome monitoring
device for early detection of neovascular age-related macular degeneration. The HOme Monitoring of the Eye
(HOME) study design - HOME Study report number 1. Contemp Clin Trials 2014; Feb 13 [Epub ahead of print] (*member, see appendix to paper) PMID: 24530651
78. Age-Related Eye Disease Study 2 (AREDS2) Research Group*, Chew EY, Clemons TE, Sangiovanni JP,
Danis RP, Ferris FL 3rd, Elman MJ, Antoszyk AN, Ruby AJ, Orth D, Bressler SB, Fish GE, Hubbard GB,
Klein ML, Chandra SR, Blodi BA, Domalpally A, Friberg T, Wong WT, Rosenfeld PJ, Agrón E, Toth CA,
Bernstein PS, Sperduto RD. Secondary Analyses of the Effects of Lutein/Zeaxanthin on Age-Related Macular Degeneration Progression: AREDS2 Report No. 3. JAMA Ophthalmol. 2014; 132(2): 142-9. doi: 10.1001/jamaophthalmol.2013.7376. (*member, see appendix to paper) PMID: 24310343
79. Writing Group for the AREDS2 Research Group*, Bonds DE, Harrington M, Worrall BB, Bertoni AG,
Eaton CB, Hsia J, Robinson J, Clemons TE, Fine LJ, Chew EY. Effect of Long-Chain ω-3 Fatty Acids and
Lutein + Zeaxanthin Supplements on Cardiovascular Outcomes: Results of the Age-Related Eye Disease
Study 2 (AREDS2) Randomized Clinical Trial. JAMA Intern Med. 2014; 174(5): 763-71. (*member, see
appendix to paper) PMID: 24638908 80. Jackson GR, Scott IU, Kim IK, Quillen DA, Iannaccone A, Edwards JG. Author response: additional
considerations in the utility of dark adaptometry for the diagnosis of age-related macular degeneration.
Invest Ophthalmol Vis Sci 2014; 55(5): 3149 [letter]. 81. Iannaccone A, Zarbin MA. Medical Therapy for Retinal Degenerative Disease: A New Era? Lancet 2014;
384(9953):1482-4. [invited editorial as comment to: “Safety and Efficacy of a Novel Oral 9-cis-retinoid
Treating Childhood Blindness due to Leber Congenital Amaurosis caused by RPE65 or LRAT mutations: a
Phase 1b Human Clinical Trial” by Koenekoop et al.] PMID: 25030841 82. Iannaccone A. Measuring Dark Adaptation in the Elderly: A Predictor of Who May Develop Macular
Degeneration? Invest. Ophthalmol. Vis. Sci. 2014; 55(8): 4790 [invited Research Highlight as comment to:
Owsley C, Huisingh C, Jackson GR, et al. Associations between abnormal rod-mediated dark adaptation
and health and functioning in older adults with normal macular health]. PMID: 25091414 83. Huntington Study Group Reach2HD Investigators*. Safety, tolerability, and efficacy of PBT2 in Huntington
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 23 of 35
84. Hood MP, Kerr NC, Smaoui N, Iannaccone A. Abnormal Cone ERGs in a Family with Congenital Nystagmus and
Photophobia Harboring a p.X423Lfs Mutation in the PAX6 Gene. Doc. Ophthalmol. 2015; 130(2): 157-64. PMID: 25555363
85. Thompson DA, Ali RR, Banin E, Branham KE, Flannery JG, Gamm DM, Hauswirth WW, Heckenlively JR, Iannaccone A, Jayasundera KT, Khan NW, Molday RS, Pennesi M, Reh TA, Weleber RW, Zacks DN, for
the The Monaciano Consortium.* The Monaciano Symposium: Recommendations for Advancing Therapeutic
Strategies for Inherited Retinal Degeneration. Invest Ophthalmol Vis Sci 2015; 56(2):918-31 – * All authors equal contributors, listed in alphabetical order after first. PMID 25667399
86. Luo X, Cideciyan AV, Iannaccone A, Roman AJ, Ditta LC, Jennings BJ, Yatsenko SA, Sheplock R,
Sumaroka A, Swider M, Schwartz SB, Wissinger B, Kohl S, Jacobson SG. Blue Cone Monochromacy: visual
function and efficacy outcome measures for clinical trials. PLoS One 2015; 10(4): e0125700. (Supplemental
material available online) PMID 25909963 87. Yatsenko SA, Bakos H, Ketchum K, Kedrov M, Kishore A, Jennings BJ, Yatsenko AN, Surti U, Woods M,
Rajkovic A, Iannaccone A. Blue cone monochromacy diagnosis by high-resolution X chromosome
microarray. Clin Genet. 2015; Jul. 8. Doi: 10.1111/cge.12638 [Epub ahead of print]. (Supplemental material available online) PMID 26153062
88. Wilkin J, Kerr NC, Byrd KW, Ward JC, Iannaccone A. Characterization of a case of pigmentary retinopathy
in Sanfilippo syndrome type IIIA associated with compound heterozygous mutations in the SGSH gene.
Ophthalmic Genetics 2015; Sep 2: 1-11. [Epub ahead of print] PMID 26331342 89. Iannaccone A, Giorgianni, F, New DD, Hollingsworth TJ, Umfress A, Alhatem A, Neeli I, Lenchik NI,
Jennings BJ, Calzada JI, Satterfield S, Mathews D, Diaz RI, Harris T, Johnson KC, Charles S, Kritchevsky
SB, Gerling IC, Beranova-Giorgianni S, Radic MZ for the Health ABC Study. Circulating autoantibodies in
age-related macular degeneration recognize human macular tissue antigens implicated in autophagy,
immunomodulation, and protection from oxidative stress and apoptosis. PLoS One 2015; 10(12): e0145323. (Supplemental material available online) PMID 26717306
90. Smith TB, Parker M, Steinkamp P, Smith N, Wilson DJ, VPA Clinical Trial Study Group*, and EZ Area Study
Group. Structure-Function Modeling of Optical Coherence Tomography and Standard Automated Perimetry in the
Retina of Patients with Autosomal Dominant Retinitis Pigmentosa. PLoS One 2016; 11(2): e0148022. (*member) PMID 26845445.
91. Iannaccone A, Carboni G, Forma G, Mutolo MG, Jennings BJ. Macular Pigment Optical Density and
Measures of Macular Function: Test-Retest Variability, Cross-Sectional Correlations, and Findings from
the Zeaxanthin Pilot Study of Response to Supplementation (ZEASTRESS-Pilot). Foods 2016; 5, 32;
doi:10.3390/foods5020032. PMID assignment in progress 92. Iannaccone A, Koirala D, Hollingsworth TJ, New DD, Lenchik NI, Beranova-Giorgianni S, Gerling IC,
Giorgianni F, Radic MZ. Retinal pigment epithelium and microglia express the CD5 antigen-like protein,
a novel autoantigen in age-related macular degeneration. Exp. Eye Res. (submitted) 93. Balem F, Tirupula K, Yanamala N, Man D, Ollesch J, Planas-Iglesias J, Waseem N, Jennings BJ, Gerwert
K, Bhattacharya SS, Iannaccone A, Klein-Seetharaman J. Molecular Properties and Disease Phenotypes of
Rhodopsin Retinitis Pigmentosa Mutants P23H and N15S. PLoS ONE (submitted) 94. Rafietaary S, Barnett JM, Kerr NC, Iannaccone A. Retinal Changes and Nerve Fiber Layer Loss in
Pediatric Patients on Vigabatrin: An electroretinogram and imaging study. JAAPOS (in preparation).
95. Epstein SR, Sollenberger EL, Jennings BJ, Sharp J, Adamus G, Iannaccone A. Clinical, functional, and
imaging findings in cancer cancer-associated retinopathy (CAR) and optic neuropathy (CAON).
Ophthalmology (under revision) 96. Smith CT, Kerr NC, Chiang J, Iannaccone A. Early stage electroretinogram and high-resolution imaging
findings in a pediatric case of KCNV2-associated retinopathy. Ophthalmic Genetics (in preparation)
97. Sollenberger EL, Birg A, Carboni G, Forma G, Adamus G, Iannaccone A. Spectral-Domain Optical
Coherence Tomography Findings in Patients with Autoimmune Neuro-Retinopathy. Invest. Ophthalmol. Vis.
Sci. (in preparation) 98. Sollenberger EL, Epstein SR, Carboni G, Forma G, Jennings BJ, Adamus G, Iannaccone A. Clinical
and functional presentation of autoimmune neuro-retinopathies. Am. J. Ophthalmol. (under revision)
99. Iannaccone A, Cox KF, Bratton M, Byrd A, Gallaher KT, Satterfield S, Johnson KC, Harris T, Johnson EJ,
Kritchevsky SB, for the Health ABC Study. Macular Pigment Optical Density in Age-Related Maculopathy.
(in preparation).
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 24 of 35
100. Iannaccone A, Bratton M, Johnson EJ, Byrd A, Gallaher KT, Kenyon E, Harris T, Satterfield S, Johnson
KC, Kritchevsky SB for the Health ABC study. Correlates of Macular Pigment Optical Density in the Elderly.
(in preparation). 101. Iannaccone A, Byrd A, Bratton M, Johnson EJ, Gallaher KT, Satterfield S, Kenyon E, Harris T, Johnson
KC, Kritchevsky SB. Inter-Racial Differences in the Relationship Between Macular Pigment Optical Density,
C-Reactive Protein and Serum Levels of Macular Carotenoids in Elderly Subjects (in preparation). 102. Iannaccone A, Bratton M, Schneck K, Wirotsko W, Stone EM, Sidjanin DJ. Adult-Onset Macular
Dystrophies: Novel Mutations in the RDS/Peripherin Gene and Comparison to non-RDS/Peripherin-linked
Phenotypes. (under revision).
Other Published Manuscripts 1. Pernini C, Leone G, Forte F, Ciccarelli ML, Iannaccone A. Validità dell'impiego della campimetria
computerizzata negli screening di base [Italian]. Proceedings of the IX Refreshment Course of the Italian
Orthoptist Association (AIO) 'La pratica perimetrica', Genova, May 11-12 1989, Giornale Italiano di Ortottica e
Tecnica Strumentale Oftalmica, 1991; 16: 28-31. 2. Rispoli E, Vingolo EM, Rispoli D, Iannaccone A. Sodium Hyaluronate (Hyalistil) in performing ERG
[Italian]. Boll. Ocul. 1991; 3: 625-630.
3. Rispoli E, Vingolo EM, Iannaccone A. Thymopentin in Retinitis Pigmentosa. Evaluation of its possible
therapeutical effects after 18 months of treatment, preliminary results. New Trends in Ophthalmology 1991;
6: 235-241. 4. Rispoli E, Iannaccone A, Di Battista V, Di Pasqua F. Clinical applications of electrofunctional techniques in
the evaluation of amblyopia [Italian]. Boll. Ocul. 1992; 71: 897-911.
5. Rispoli E, Iannaccone A, Moretti S, Vingolo EM. The electroretinogram in retinitis pigmentosa: case
8. Proto F, Iannaccone A, Giusti C, De Leo A, Vingolo EM. Kearns-Sayre Syndrome (KSS): case report
and review of the literature [Italian]. Ann.Ottalmol. Clin. Ocul. 1994; 120: 149-154.
9. Mutolo PA, Ciccarelli ML, Iannaccone A. Schubert-Bornschein complete congenital stationary night blindness (SB-
CSNB1) and tilted disc syndrome. A case report [Italian]. Ann.Ottalmol. Clin. Ocul. 1994; 120: 421-431. 10. Forte R, Iannaccone A, De Propris G, Del Beato P, Rinaldi R, Roncati S, Vingolo EM, Pannarale MR. The
optic nerve in patients with the Laurence-Moon-Bardet-Biedl phenotype: a clinical and functional study.
[Italian] Boll. Ocul. 1996; 75 (suppl. 4): 115-124. 11. Iannaccone A, Forte R, Spaccini L, Tanzilli P, Vingolo EM, Roncati S, Rispoli E. Autosomal dominant cone
dystrophy mimicking optic atrophy: description of a genealogy. [Italian] Boll. Ocul. 1996; 75 (suppl. 4):
147-158. 12. Mutolo PA, Ciccarelli ML, Iannaccone A, Santamaria S, Cataldi C. Monocular familial Brown syndrome:
description of a genealogy [Italian]. Proceedings of the XIV Congress of the Italian Society of Pediatric
Ophthalmology (SIOP), Parma, May 29-31, 1997. Casa Editrice Mattioli, Fidenza (PR), Italy: pp. 203-210. 13. Iannaccone A. Retinitis Pigmentosa. Invited Update to Review No. 21. National Organization for
movimenti oculari e ambliopia, glaucoma, Casa Editrice Mattioli, Fidenza, 1991, p. 253-262. 2. Rispoli E, Vingolo EM, Onori P, Iannaccone A, Steindl K. Comparazione di alcuni parametri clinici e
strumentali nella Retinite Pigmentosa: ERG ed alterazioni del campo visivo [Italian]. In: Cordella M, Baratta
G, Macaluso C, eds., Retinite Pigmentosa, movimenti oculari e ambliopia, glaucoma, Casa Editrice Mattioli,
Fidenza, 1991, p. 263-273. 3. Pannarale MR, Rispoli E, Vingolo EM, Pannarale L, Forte R, Iannaccone A. Cataract complicated by
Clinical and Genetic Research. CRC Press, Boca Raton, 1992; pp. 145-149. 4. De Propris G, Iannaccone A, Amodeo S, Onori P, Pierazzi C. Clinical observations in 10 cases of
Laurence-Moon-Bardet-Biedl Syndrome. [Italian] Proceedings of the 72nd National Congress of the Italian
Society of Ophthalmology. Arti Grafiche Dial, Mondovì (Cuneo), 1993, p. 1089-1100. 5. Forte R, Onori P, Steindl K, Iannaccone A, Pierazzi MC, De Ruggieri G, Grammatico P. Visual acuity in
retinitis pigmentosa patients with defined inheritance pattern. In: E. Rinaldi, ed.: Retinitis Pigmentosa.
Present knowledge and outlook, Edizioni Liviana Medicina, Naples, 1993; pp. 262-272. 6. Steindl K, Grammatico B, Forte R, Iannaccone A, Vingolo EM. Gyrate atrophy: clinical and genetic
aspects. In: E. Rinaldi, ed.: Retinitis Pigmentosa. Present knowledge and outlook, Edizioni Liviana
Medicina, Naples, 1993; pp. 345-350. 7. Vingolo EM, Iannaccone A, Forte R, Tanzilli P, Sciò F. Thymopentin in the treatment of retinitis pigmentosa:
Results after a three-year follow-up. In: E. Rinaldi, ed.: Retinitis Pigmentosa. Present knowledge and outlook,
Edizioni Liviana Medicina, Naples, 1993; pp. 437-445. 8. Del Porto G, Vingolo EM, David D, Steindl K, Wedemann H, Forte R, Iannaccone A, Gal A, Pannarale MR.
Clinical features of autosomal dominant retinitis pigmentosa associated with the Gly-188-Arg mutation of
the rhodopsin gene. In: Hollyfield JG, La Vail MM, Anderson RE, (eds) Retinal Degeneration: Clinical and
Laboratory Applications. Plenum Press, New York, 1993; pp. 91-101. 9. Iannaccone A, Vingolo EM. Psychophysical determination of visual function in patients with tapetoretinal
degenerations [Italian]. In: Sviluppo ed alterazione della visione, Proceedings of the 25th Meeting of the
Italian Orthoptist Association. Verduci Editore, Rome, 1994, p. 249-253. 10. Vingolo EM, Pannarale L, Forte R, Iannaccone A, Pannarale MR. The immune system and retinitis
pigmentosa: Pathophysiological bases for new therapeutic approaches. [Italian] Proceedings of the 73rd
National Congress of the Italian Society of Ophthalmology. Arti Grafiche Dial, Mondovì (Cuneo), 1994, p. 379-389.
11. Cassone-Faldetta M, Gobbi F, Laurenti O, Pannarale L, Iannaccone A, Vingolo EM. Central retinal vein
occlusion in chronic lymphoid leukemia (CLL): case report. Proceedings of the 12th Congress of the
European Association of Internal Medicine. ELA, Grupo Aran, Madrid, 1995: p. 337-341. 12. Vingolo EM, Bellelli A, Pannarale L, Iannaccone A, Forte R, Santori M, Grenga R. Cataractogenesis in
retinitis pigmentosa: spectroscopic fluorescence analysis of aqueous humor composition. In: Anderson RE,
LaVail MM, Hollyfield JG, eds, Degenerative Diseases of the Retina. Plenum Press, New York, 1995: 403-407. 13. Iannaccone A, Vingolo EM, Grammatico B, Forte R, Tanzilli P, De Bernardo C, Rispoli E, Del Porto G,
Pannarale MR. Scotopic threshold responses and rod intensity-response functions as sensitive indicators
of the carrier status in X-linked recessive retinitis pigmentosa. In: Anderson RE, LaVail MM, Hollyfield JG,
eds, Degenerative Diseases of the Retina. Plenum Press, New York, 1995: 371-376. 14. Tanzilli P, Iannaccone A, Rispoli E, Del Beato P, Vingolo EM. Cone-rod dystrophy with progressive selective
involvment of the OFF cone system. [Italian] Proceedings of the 74th National Congress of the Italian Society of
Ophthalmology, Rome, November 17-20, 1994. Casa Editrice Mattioli, Fidenza (PR), Italy, 1995: 705-714.
15. Iannaccone A, Vingolo EM, Tanzilli P, Del Beato P, Pannarale MR. Long-term results of a pilot study on
thymopentin in the treatment of retinitis pigmentosa: pathophysiological considerations [Italian] Proceedings
of the IV National Congress of the Italian Association for Ocular Pharmacology (AISFO), Isola di Capri,
October 13-15 1994. Mediconsult, Catania, Italy, 1996; p. 461-473. 16. Iannaccone A, Falsini B, Haider N, Del Porto G, Stone EM, Sheffield VC. Bardet-Biedl syndrome. Phenotypic
characteristics associated with the BBS4 locus. In: Hollyfield JG, La Vail MM, Anderson RE, eds, Retinal
Degenerative Diseases and experimental Therapy. Kluwer Academic/Plenum Press, New York, 1999: pp. 187-199.
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 26 of 35
Published and presented abstracts 1. Iannaccone A, Tanzilli P, Rispoli M. ERG recording: low-noise techniques in retinitis pigmentosa
Invest. Ophthalmol. Vis. Sci. 1992; 33 (4 Suppl): 840. 2. Vingolo EM, Iannaccone A, Onori P, Steindl K, Rispoli E. Correlations between perimetric and
3. Vingolo EM, Rispoli EM, Iannaccone A, Steindl K, Tanzilli P, Del Porto G, Pannarale MR. Scotopic threshold
response abnormalities in X-linked RP carriers. Invest. Ophthalmol. Vis. Sci. 1993; 34 (4 Suppl.): 1271. 4. Iannaccone A, Rispoli E, Vingolo EM, Onori P, Pannarale MR. Progressive night blindness and
supernormal ERG responses: a case report. Invest. Ophthalmol. Vis. Sci. 1993; 34 (4 Suppl.): 1271. 5. De Propris G, Iannaccone A, Vingolo EM, Amodeo S, Leonardi A, Pannarale MR. Ophthalmological features
of the Laurence-Moon-Bardet-Biedl phenotype. Invest. Ophthalmol. Vis. Sci. 1993; 34 (4 Suppl.): 1369. 6. Vingolo EM, Palestini M, Scalfati M, Mechella M, Iannaccone A, Teofili MT, Forte R. Epithelial corneal
abnormalities in Alport’s syndrome: a case report. SPOVS Proceedings. Proc. Vis. Sci. 1993; p.11.
7. Forte R, Vingolo EM, Iannaccone A, Gobbi F, Rispoli E, Pannarale MR. Contrast sensitivity function for the clinical evaluation of cystoid macular edema in retinitis pigmentosa. Proposal of a new therapeutic approach by Deflazacort. SPOVS Proceedings. Proc. Vis. Sci. 1993; p. 28.
8. Iannaccone A, Vingolo EM, Tanzilli P, Rispoli E. The Scotopic Threshold Response in different forms
of Congenital Stationary Night Blindness. Invest. Ophthalmol. Vis.Sci. 1994; 35 (4 Suppl.): 1377. 9. Vingolo EM, Iannaccone A, De Propris G, Tanzilli P, Rispoli E, Pannarale MR. Electroretinographic
abnormalities in the Laurence-Moon-Bardet-Biedl phenotype. Invest. Ophthalmol. Vis.Sci. 1994; 35 (4 Suppl.): 1958.
10. Forte R, Pannarale L, Iannaccone A, Vingolo EM, Santi G, Pannarale MR. Cystoid macular edema in
retinitis Pigmentosa: clinical and functional evaluation of patients treated with deflazacort. Invest. Ophthalmol. Vis.Sci. 1994; 35 (4 Suppl.): 1958.
11. Rispoli E, Vingolo EM, Iannaccone A, Forte R, Grammatico B, De Bernardo C, Steindl K, Pannarale
MR. Electroretinographic measures in carriers of X-linked recessive retinitis pigmentosa Invest. Ophthalmol. Vis.Sci. 1994; 35 (4 Suppl.): 2159.
12. Iannaccone A, Vingolo EM, Tanzilli P, Forte R, Rispoli E. Steady-state flash visual evoked potentials in the
Laurence-Moon-Bardet-Biedl syndrome. Preliminary observations. 5th International Evoked Potentials Symposium, Milan, Italy, September 4-7, 1994: p. 56.
13. Rispoli E, Iannaccone A, Vingolo EM, Rispoli M. Rod ERG frequency-response function: normative data and
clinical applications. Invest. Ophthalmol. Vis. Sci. 1995; 36: S446. 14. Vingolo EM, Iannaccone A, Rispoli E, Grammatico B, Pannarale L, De Bernardo C. Different rod pathways’
abnormalities in RP2 and RP3 XLRP carriers. Invest. Ophthalmol. Vis. Sci. 1995; 36: S925. 15. Iannaccone A, Vingolo EM, Forte R, Rispoli M, Arrico L, Rispoli E. Clinical and electroretinographic
findings in the Goldmann-Favre vitreoretinal dystrophy. Invest. Ophthalmol. Vis. Sci. 1995; 36: S926. 16. Iannaccone A, Cideciyan AV, Sheffield VC, Stone EM, Jacobson SG. Phenotype of chromosome 8q-
linked autosomal dominant retinitis pigmentosa. Invest. Ophthalmol. Vis. Sci. 1996; 37 (suppl. 4): S345. 17. Lyubarsky A, Iannaccone A, Chen J, Xu J, Pugh EN. Cone PII component of murine ERG isolated by
flashed background. Soc. Neurosci. Abs. 1996: 22 (Part 1): 121. 18. Haider N, Kwitek-Black AE, Iannaccone A, Carmi A, Elbedour K, Nishimura DY, Stone EM, Sheffield VC.
Genetic and physical fine mapping of the chromosome 15 Bardet-Biedl syndrome (BBS4) locus. Am. J. Hum. Genet. 1996; 59: A220.
19. Iannaccone A, Grunwald JE, DuPont J. The effect of 5-isosorbide monitrate (ISMO) on optic nerve head
and foveal choroidal blood flow. Invest. Ophthalmol. Vis. Sci. 1997; 38 (suppl. 4): S275. 20. Iannaccone A, Letizia C. Plasma endothelin-1 concentrations in patients with retinal vascular disease.
Proceedings of the University of Tennessee-Memphis Research Day, Memphis, TN, Nov. 21, 1997, p. 17. 21. Iannaccone A. Clinical manifestations of autosomal dominant retinitis pigmentosa associated with distinct
rhodopsin gene mutations. Proceedings of the University of Tennessee-Memphis Research Day, Memphis, TN, Nov. 21, 1997, p. 18.
22. Iannaccone A. Correlation between Goldmann perimetry and Maximal ERG response in patients with Usher
syndrome. Proceedings of the University of Tennessee-Memphis Research Day, Memphis, TN, Nov. 21, 1997, p. 18.
23. Iannaccone A. Rod-driven and extramacular contributions to the 10-Hz flash visual evoked potential. Invest.
Ophthalmol. Vis. Sci. 1998; 39 (suppl. 4): S185. 24. Iannaccone A. Phenotypical differences in autosomal dominant retinitis pigmentosa associated with distinct
31. Iannaccone A, Ciccarelli ML, Orten DJ, Weston MD, Baldi A, Jablonski MM, Kimberling WJ. Kinetics of visual field
loss in Usher syndrome type 2. [ARVO abstract] Invest. Ophthalmol. Vis. Sci. 2001; 42(4 Suppl): S77. 32. Wohabrebbi A, Iannaccone A, Jablonski MM. Downregulation of a novel photoreceptor protein
http://www.iovs.org/search.dtl?arvomtgsearch= true 38. Wang XF, Iannaccone A, Wohabrebbi A, Jablonski MM. Human Anti-Photoreceptor (HAP-1) Expression in
Abstract 55. Free access online at: http://www.iovs.org/search.dtl?arvomtgsearch=true 43. Meng S, Satterfield S, Iannaccone A, Kenyon E, Harris T, Newman A, Simonsick E, Kritchevsky SB, for the
Health ABC Study. Self-reported and measured visual function and walking difficulty in community-dwelling
older adults. [SER (Society for Epidemiologic Research) abstract] Am. J. Epidemiol. 2004; S2 (Abstract 005)
- Free access online at: http://www.epiresearch.org/meeting/abstractbook.pdf 44. Mura M, Sereda C, MacDonald IM, Iannaccone A. Clinical and functional findings in a family with
choroideremia due to a deletion of the entire CHM gene. [ARVO abstract] Invest. Ophthalmol. Vis. Sci. 2005;
46: E-Abstract 534. Free access online at: http://www.iovs.org/search.dtl?arvomtgsearch=true 45. Iannaccone A, Gallaher K, Mura M, Kenyon E, Harris TL, Todd WA, Harris T, Johnson KC, Satterfield S,
Kritchevsky SB. Macular Pigment Optical Densitometry in the Elderly: Findings in a Large Biracial Mid-South
Sample and Effect of Optical Blur in Pseudophakic Subjects. [ARVO abstract] Invest. Ophthalmol. Vis. Sci.
2005; 46: E-Abstract 1567. Free access online at: http://www.iovs.org/search.dtl?arvomtgsearch= true 46. Gallaher K, Mura M, Todd WA, Kenyon E, Harris TL, Satterfield S, Harris T, Johnson KC, Kritchevsky SB,
Iannaccone A. Test-Retest Variability of Macular Pigment Optical Densitometry in the Elderly: Findings from
the Health ABC ARMA Study. [ARVO abstract] Invest. Ophthalmol. Vis. Sci. 2005; 46: E-Abstract 1570. Free
access online at: http://www.iovs.org/search.dtl?arvomtgsearch=true 47. Wang XF, Iannaccone A, Jablonski MM. Contribution of Müller cells toward the regulation of
recipient. Free access online at: http://www.iovs.org/search.dtl? arvomtgsearch=true 51. Iannaccone A, Sahu PD, Atkins S, Wang X-F, Ayyagari R, Jablonski MM. Evidence for cone and rod
dysfunction in autosomal dominant Stargardt-like disease associated with a 5-bp deletion in ELOVL4.
XVII International Congress of Eye Research, Buenos Aires, Argentina, October 29 – November 4, 2006. 52. Jablonski MM, Iannaccone A, Reynolds DH, Gallaher P, Allen S, Wang XF, Reiner AJ. Age-related decline
of VIP-positive submacular vasoactive neural networks. XVII International Congress of Eye Research,
Buenos Aires, Argentina, October 29 – November 4, 2006. 53. Renzi LM, Iannaccone A, Gallaher KT, Satterfield S, Kenyon E, Harris T, Johnson KC, Kritchevsky SB,
Schalch W, Johnson EJ. Relationships Among Macular Pigment Optical Density (MPOD), Serum Lutein (L),
http://www.iovs.org/search.dtl? arvomtgsearch=true 61. Iannaccone A, Johnson EJ, Armstrong JT, Kenyon E, Harris T, Satterfield S, Johnson KC, Kritchevsky
SB. Macular Pigment Optical Density, C-Reactive Protein, and Serum Lutein and Zeaxanthin in the Elderly.
http://www.iovs.org/search.dtl? arvomtgsearch=true 62. Iannaccone A, Miyake N, Ciccarelli ML, Cheng L, Andrews C, Campioni M, Baldi A, Kerr NC, Engle EC.
Autosomal dominant Duane Retraction Syndrome (adDRS): Phenotypic and molecular effects of the
G228S mutation in the CHN1 (DURS2) gene. AAPOS meeting, San Francisco, CA, April 17-21, 2009. 63. Iannaccone A, Spencer K, Olson LM, Armstrong JT, Johnson KC, Kenyon E, Satterfield S, Johnson EJ,
Kritchevsky SB, Haines JL. Y402H Variant in Complement Factor H (CFH): Association with Age-Related
Maculopathy (ARM) and Correlation with Macular Pigment Optical Density (MPOD), Serum C-Reactive
http://www.iovs.org/search.dtl? arvomtgsearch=true 66. Kerr NC, Iannaccone A, Calzada JI, Kinnick TR, Stone EM. Bilateral Neovascular Membranes in a Child
With Early-onset Autosomal Recessive Best's Vitelliform Macular Dystrophy (arBVMD) Due to Compound
http://www.iovs.org/search.dtl?arvomtgsearch=true 74. Adamus G, Brown L, David L, Schiffman J, Iannaccone A. Identification of Novel Antigenic Targets for
Autoantibodies Against Optic Nerve Antigens in Autoimmune Neuro-Retinopathy. Invest. Ophthalmol. Vis.
Sci. 2010; 51: E-Abstract 5780. Free access online at: http://www.iovs.org/ search.dtl?arvomtgsearch=true 75. Iannaccone A, Neeli I, Lenchik N, Krishnamurthy P, Gerling IC, Radic MZ. Serological Patterns of
Autoreactivity and Identification of Novel Auto-Antigens in Age-Related Macular Degeneration (AMD).
search.dtl?arvomtgsearch=true 76. Iannaccone A, Neeli I, Krishnamurthy P, Lenchik N, Wan H, Gerling IC, Desiderio DM, Radic MZ.
Autoimmunity in Age-Related Macular Degeneration: A Possible Role Player in Disease Development
and Progression. XIVth International Symposium on Retinal Degeneration, Mont-Tremblant, Quebec,
Canada, July 13-17, 2010. 77. Rhadakrishnan-Iyer SS, Forma G, Carboni G, Mutolo MG, Adamus G, Iannaccone A. Patterns of
Visual Field Patterns and Electrophysiological Findings in Autoimmune Neuro-Retinopathy (AINR).
American Academy of Ophthalmology meeting, Chicago, IL, Oct. 16-19, 2010. 78. Omar A, Wang Z, Racine J, Iannaccone A, Lopez I, den Hollander A, Majewski J, Koenekoop RK.
Combining Homozygosity Mapping With Exome Capture To Identify The Causal Gene For Pericentral
access online at: http://www.iovs.org/ search.dtl?arvomtgsearch=true 83. Forma G, Carboni G, Jennings BJ, Iannaccone A. Measures Of Macular Function After Dietary
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 31 of 35
86. Hoffman JD, Olson LM, Spencer KL, Scott WK, Agarwal A, Pericak-Vance MA, Kovach JL, Schwartz S, Iannaccone A, Haines JL. Ethnic Differences In Htra1/arms2 Association In Age-related Macular
http://www.iovs.org/ search.dtl?arvomtgsearch=true 87. Iannaccone A. Macular Pigment Optical Density: Findings in Aging and Age-Related Maculopathy and
Response to Supplementation (Invited speaker). Ocular Nutrition Society 2011 Educational Symposium,
Boston, October 10, 2011. 88. Cox K, Kerr NC, Kedrov M, Nishimura D, Jennings BJ, Stone EM, Sheffield VC, Iannaccone A. Phenotypic
Expression of Bardet-Biedl Syndrome in Patients Homozygous for the Common M390R Mutation in the BBS1
Gene. Pre-ARVO Retinal Ciliopathies 2012 Vision Research meeting, Ft. Lauderdale, FL, May 4-5, 2012. 89. Iannaccone A, Umfress A, Neeli I, Murphy L, Krishnamurthy P, Lenchik, N, Gerling IC, Radic MZ. Evidence
for Auto-Antibodies (auto-Abs) Recognizing Human Macular Tissue Antigens in Serum Samples of Patients
online at: http://www.iovs.org/ search.dtl?arvomtgsearch=true 93. Jackson GR, Scott IU, Kim IK, Bressler NM, Quillen DA, Iannaccone A, Edwards JG. Evaluation of the
AdaptDx™ for detection of age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 2014; 55: E-
Abstract 2996. Free access online at: http://www.iovs.org/ search.dtl?arvomtgsearch=true 94. Epstein RS, Sollenberger E, Adamus G, Iannaccone A. Clinical, functional, and imaging findings in cancer
95. Sollenberger E, Epstein RS, Adamus G, Iannaccone A. Clinical characteristics of autoimmune neuro-retinopathy (AINR). Invest. Ophthalmol. Vis. Sci. 2014; 55: E-Abstract 2509. Free access online at: http://www.iovs.org/ search.dtl?arvomtgsearch=true
96. Ho A, Smith T, Hariri A, Chegarnov E, Ferris FL, Van Veldhuisen P, Sadda SR, Weleber RG, Birch DG, VPA Clinical Trial Group, EZ Area Working Group. Area Measurement of the Ellipsoid Zone (EZ) by SD-OCT and
its Correlation with Visual Field Identifies a Potential Anatomical Endpoint for Clinical Trials in Retinitis Pigmentosa (RP). Invest. Ophthalmol. Vis. Sci. 2014; 55: E-Abstract 3380. Free access online at: http://www.iovs.org/search.dtl? arvomtgsearch=true
97. New DD, Lenchik NI, Giorgianni F, Alhatem AH, Beranova-Giorgianni S, Gerling IC, Radic MZ, Iannaccone A.
The apoptosis inhibitor of macrophage/CD5 molecule-like protein (AIM/CD5L) is expressed in the human retina and is a target of autoreactivity in age-related macular degeneration (AMD). Invest. Ophthalmol. Vis. Sci. 2014; 55: E-Abstract 65. Travel Award recipient. Free access online at: http://www.iovs.org/
search.dtl?arvomtgsearch=true 98. Alhatem AH, Lenchik NI, Beranova-Giorgianni S, Klingeborn M, New DD, Giorgianni F, Gerling IC, Radic MZ,
Bowes Rickman C, Iannaccone A. The Apolipoprotein E4 Targeted Replacement (APOE4 TR) Mouse Model of Age-Related Macular Degeneration (AMD) Exhibits Anti-Retinal Autoreactivity. Invest. Ophthalmol. Vis. Sci. 2014; 55: E-Abstract 1173. Travel Award recipient. Free access online at: http://www.iovs.org/
search.dtl?arvomtgsearch=true 99. Iannaccone A, Alhatem AH, Lenchik NI, Giorgianni F, New DD, Beranova-Giorgianni S, Gerling IC,
Ufret-Vincenty RL, Radic MZ. Evidence for Anti-Retinal Auto-Antibodies (AAbs) in the Complement Factor H Chimeric Transgenic (Cfh-Tg) Mouse Model of Age-Related Macular Degeneration (AMD). Invest. Ophthalmol. Vis. Sci. 2014; 55: E-Abstract 1205. Free access online at: http://www.iovs.org/ search.dtl?arvomtgsearch=true
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 32 of 35
100. Iannaccone A, New DD, Giorgianni F, Lenchik NI, Alhatem AH, Beranova-Giorgianni S, Gerling IC, Radic
MZ. Serum Auto-Antibody (AAb) Studies in Patients With AMD Identify the Apoptosis Inhibitor of
Macrophage / CD5 Molecule-Like Protein as a Novel Human Retinal Protein and an AAb Target in AMD.
PO237, American Academy of Ophthalmology meeting, Chicago, IL, Oct. 18-22, 2014. 101. Epstein RS, Sollenberger E, Adamus G, Iannaccone A. Clinical, Functional, and Imaging Characteristics of
Cancer-Associated Retinopathy and Optic Neuropathy. PO232, American Academy of Ophthalmology meeting, Chicago, IL, Oct. 18-22, 2014 (poster received highest grades for its subject area by the AAO 2014 Program Committee).
102. Iannaccone A, Sollenberger E, Epstein RS, Birg A, Adamus G. Optic Nerve/Retinal Ganglion Cell
Involvement in Autoimmune Retinopathies Resulting in Autoimmune Neuroretinopathy. PO547, American Academy of Ophthalmology meeting, Chicago, IL, Oct. 18-22, 2014.
103. Barnett JM, Kerr NC, Iannaccone A. Retinal Dysfunction and Nerve Fiber Layer Loss in Pediatric Patients
on Vigabatrin: An ERG and SD-OCT Study. AAPOS Meeting, New Orleans, LA, March 25-29, 2015 (presentation received Best Poster Award recognition, Retina section).
104. Epstein RS, New DD, Hollingsworth TJ, Meunier I, Lenchik NI, Lu Q, Gerling IC, Hamel C, Radic MZ, Iannaccone A. Defective mer-tyrosine kinase (mer-TK) function is associated with anti-arrestin and anti-
interphotoreceptor retinoid-binding protein (IRBP) autoantibodies (AAbs) in Mer, Axl, Tyro3 -/- (TAM) mice and in autosomal recessive retinitis pigmentosa (arRP) patients with a null MERTK mutation. Invest. Ophthalmol. Vis. Sci. 2015; 56: E-Abstract 169. Free access online at: http://www.iovs.org/ search.dtl?arvomtgsearch=true
105. Iannaccone A, New DD, Giorgianni F, Lenchick NI, Beranova-Giorgianni S, Gerling IC, Radic MZ. Sera from subjects with age-related macular degeneration (AMD) exhibit strong autoreactivity against human macular Heat Shock Proteins (HSPs). Invest. Ophthalmol. Vis. Sci. 2015; 56: E-Abstract 815. Free access online at: http://www.iovs.org/ search.dtl?arvomtgsearch=true
Iannaccone A. The Cu/Zn+ superoxide dismutase knockout mouse (Sod1-/-), a model of age-related
macular degeneration (AMD), exhibits anti-retinal autoantibodies (AAbs) and marked signs of intraretinal inflammation prior to onset of an AMD-like phenotype. Invest. Ophthalmol. Vis. Sci. 2015; 56: E-Abstract 3986. Free access online at: http://www.iovs.org/ search.dtl?arvomtgsearch=true (Dr. New selected to be session moderator)
107. Hollingsworth TJ, New DD, Giorgianni F, Lenchik NI, Beranova-Giorgianni S, Gerling IC, Lu Q, Wang Y, Radic MZ, Iannaccone A. Peptidylarginine deiminase (PAD4) expression and citrullination levels in normal
and mouse retinas and in murine models of late (Sod1-/-) and early-onset (Tyro3-/-, Axl-/-, Mertk-/- or TAM mice) retinal degeneration. Invest. Ophthalmol. Vis. Sci. 2015; 56: E-Abstract 4636. Free access online at: http://www.iovs.org/ search.dtl?arvomtgsearch=true
108. Koirala D, Iannaccone A, Radic MZ, Hollingsworth TJ, Gerling IC, Beranova-Giorgianni S, Giorgianni F. The
CD5-like (CD5L) protein is expressed by retinal pigment epithelium (RPE) cells and is a key role player in the uptake of oxidized low-density lipoproteins (oxLDL). Invest. Ophthalmol. Vis. Sci. 2016; 57: E-Abstract 5014. Free access online at: http://www.iovs.org/ search.dtl?arvomtgsearch=true
109. Iannaccone A, Radic MZ, Beranova-Giorgianni S, Lenchik N, Hollingsworth TJ, Gerling IC, Giorgianni F.
Circulating autoantibodies in age-related macular degeneration (AMD) recognize human macular tissue antigens implicated in immunomodulation, protection from oxidative stress and apoptosis, and autophagy. Invest. Ophthalmol. Vis. Sci. 2016; 57: E-Abstract 6560. Free access online at: http://www.iovs.org/ search.dtl?arvomtgsearch=true
Other delivered presentations (abstract or proceedings not published) 1. Vingolo EM, Rispoli E, Iannaccone A, Pannarale MR. Hypothesis of immunological treatment of retinitis
pigmentosa: a pilot study with Thymopentin, preliminary results. 2nd Meeting of the Schepens International
Society, Rome, Italy, September 12-16, 1989. 2. Rispoli E, Vingolo EM, Zicari D, Iannaccone A, Napoli A, Gerlini G, Pachì A, Fallucca F. Dynamic
electroretinogram in the evolution of diabetic retinopathy in pregnancy. 2nd International Symposium on
Diabetes and Pregnancy, Fiuggi Terme, Italy, October 27-29, 1989. 3. Rispoli E, Vingolo EM, Iannaccone A. Thymopentin (Timunox) in retinitis pigmentosa: Evaluation of its
therapeutical effects after 18 months of treatment. Preliminary results. XXVI International Congress of
Ophthalmology (ICO), Singapore, March 18-24, 1990. 4. Steindl K, Forte R, Costanzi Porrini S, Iannaccone A, Piane M. Retinitis pigmentosa (RP): Genetic Program. 6º
World Congress of the International Retinitis Pigmentosa Association (IRPA), Dublin, Ireland, July 19-22, 1990.
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 33 of 35
5. Forte R, Di Iullo M, Di Marcantonio F, Ruggiero L, Steindl K, Iannaccone A, Vingolo EM, Cedrone C.
Psychological aspects of patients with retinitis pigmentosa (RP): analysis of subjective and objective
parameters. 6º World Congress of the International Retinitis Pigmentosa Association (IRPA), Dublin, Ireland,
July 19-22, 1990. 6. Steindl K, Forte R, Costanzi Porrini S, Iannaccone A. Distribution of genetic types of retinitis pigmentosa (RP):
review and personal casistic. 6º World Congress of the International Retinitis Pigmentosa Association (IRPA),
Dublin, Ireland, July 19-22, 1990. 7. Vingolo EM, Forte R, Iannaccone A, Pannarale L, Steindl K. Retinal pigmentations: a genetic-clinical
contribution to differential diagnosis. 6º World Congress of the International Retinitis Pigmentosa Association
(IRPA), Dublin, Ireland, July 19-22, 1990. 8. Iannaccone A, Vingolo EM, Forte R, Arrico L, Pannarale MR. Progressive bilateral peripapillary RPE
disturbance with perimetric and electroretinographic evidence of cone impairment. International Workshop on
Retinal Cone Dystrophies, Moorfields Eye Hospital, London, U.K., March 26-27, 1993. 9. Iannaccone A, De Propris G, Pannarale L, Amodeo S, Vingolo EM, Pannarale MR. Clinical survey of 12
cases of Laurence-Moon-Bardet-Biedl Syndrome. 4th Meeting of the Schepens International Society, Hong
Kong, March 30-April 2, 1993. 10. Forte R, Vingolo EM, Iannaccone A, Pannarale L, Pannarale MR. Clinical and electrofunctional evaluation of
a gyrate atrophy pedigree. 4th Meeting of the Schepens International Society, Hong Kong, March 30-April 2,
1993. 11. Vingolo EM, Iannaccone A, Rispoli E, Pannarale L, Amodeo S, Pannarale MR. Three-year experience in
the treatment of retinitis pigmentosa with thymopentin. 4th Meeting of the Schepens International Society,
Hong Kong, March 30-April 2, 1993. 12. Iannaccone A, Giusti C, Forte R, Zompatori L, Pannarale L, Vingolo EM. Simple microphthalmos complicated
by central retinal vein occlusion and hypertensive uveitis. 34th Meeting of the Association for Eye Research
(AER), Granada, Spain, September 15-18, 1993. 13. Grenga R, Bellelli A, Santori M, Iannaccone A, Forte R, Vingolo EM, Pannarale L. Spectroscopic analysis of
acqueous composition in retinitis pigmentosa. 34th Meeting of the Association for Eye Research (AER),
Granada, Spain, September 15-18, 1993. 14. Iannaccone A, Vingolo EM, Tanzilli P, Forte R, Pannarale L, De Propris G, Rispoli E, Pannarale MR.
Electroretinographic features of patients with the Laurence-Moon-Bardet-Biedl phenotype. [Italian] 1st
National Retinitis Pigmentosa Day, December 11, 1993. 15. Zompatori L, Iannaccone A, Forte R, Pannarale L, Vingolo EM, Pannarale MR. Ultrasonography as an aid for the
diagnosis of cilio-choroidal effusion in microphthalmic eyes. 15th Congress of the Societas Internationalis pro
Diagnostica Ultrasonica in Ophthalmologia (SIDUO), Cortina d'Ampezzo, Italy, January 22-27, 1994.
16. Zompatori L, Forte R, Iannaccone A, Pannarale L, Vingolo EM, Pannarale MR. Ultrasonographic
measurements in the diagnosis of simple microphthalmos. 15th Congress of the Societas Internationalis
pro Diagnostica Ultrasonica in Ophthalmologia (SIDUO), Cortina d'Ampezzo, Italy, January 22-27, 1994. 17. Iannaccone A, Vingolo EM, Tanzilli P, Del Beato P, Santecola R, Rispoli E. Analysis of threshold ERG
responses (STR) in Schubert-Bornschein’s congenital stationary night blindness (SB-CSNB) type 1 and
2. [Italian] 1st Meeting of the Central Italian Ophthalmological Society (SOCI), Rome, Italy, May 13, 1994. 18. Forte R, Iannaccone A, Amoroso L, Vingolo EM, Pannarale MR. Deflazacort as a treatment for cystoid macular
edema in retinitis pigmentosa. 1st Meeting of the Central Italian Ophthalmological Society (SOCI), Rome, Italy,
May 13, 1994. 19. Forte R, Iannaccone A, Gargiulo P, Pierazzi MC, Bosco D, Pantaleo A., Vingolo EM. Acetazolamide as a
treatment for macular edema in patients with diabetic retinopathy. [Italian] 15th Congress of the Italian
Society of Diabetology, Rome, Italy, May 19-21, 1994. 20. Iannaccone A, Forte R, Tanzilli P, Vingolo EM, Roncati S, Rispoli E. Electroretinographic findings in a case
of progressive bilateral atypical cone-rod-like retinopathy. ISCEV @ ARVO Western Hemisphere Meeting,
Deerfield Beach, Florida, May 13, 1995. 21. Iannaccone A. The role of electrophysiology in the diagnosis of retinal and optic nerve functional abnormalities.
Alumni and Residents Day, Coleman Building, UT Department of Ophthalmology, Memphis, May 30, 1997.
22. Johnson DA, Jablonski MM, Iannaccone A. Retinal degenerations and immune system: Update on current
laboratory investigations. Memphis Vision Interest Group Meeting, Coleman Building, UT Department of
Ophthalmology, Memphis, January 26, 1998.
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 34 of 35
23. Iannaccone A. Establishing meaningful genotype-phenotype correlations: Allelic heterogeneity in autosomal
dominant retinitis pigmentosa due to rhodopsin mutations. Memphis Vision Interest Group Meeting, UT
Department of Anatomy and Neurobiology, Link Building, November 19, 1998. 24. Iannaccone A. The ABCs of the ERG. 2nd Annual Clinical Update for the Comprehensive
Ophthalmologist, Peabody Hotel, Memphis, TN, December 12, 1998.
25. Iannaccone A. The importance of Genotype-Phenotype Correlations in Hereditary Retinal Diseases.
Molecular Biology/Molecular Genetics of the Visual System. 1999 UT Memphis Vision Research Symposium,
March 26, 1999. 26. Iannaccone A, Brewer VB, Spiegel PH, Kerr NC, Taylor JS, Pivnick EK. Visual evoked potential (VEP)
abnormalities in children with neurofibromatosis type 1 (NF1): Neuropsychological and
neuroanatomical correlates. 37th ISCEV Symposium, Eilat, Israel, April 11-16, 1999. 27. Iannaccone A. Looks like AMD, but it isn’t. Memphis Eye Society Meeting, Clarks Tower, Memphis, January
19, 2000.
28. Iannaccone A. Macular degeneration: Clinical-genetic correlates. 3rd Annual Clinical Update for the
Comprehensive Ophthalmologist, Peabody Hotel, Memphis, TN, January 22, 2000.
29. Iannaccone A. Maximal ERG response in retinitis pigmentosa due to distinct rhodopsin mutations: physio-
pathogenetic and prognostic implications. 38th ISCEV Symposium, Sydney, Australia, February 13-17, 2000. 30. Iannaccone A. Studies of retinal function in Usher syndrome. Alumni and Residents Day, Coleman Building,
University of Memphis, UT Department of Ophthalmology, Memphis, June 9, 2000.
31. Iannaccone A, Swain PK, Baldi A, Conciatori M, Ciccarelli ML, Swaroop A. Familial cone-rod dystrophy with
cystoid macular edema. Alumni and Residents Day, Coleman Building, University of Memphis, UT Department
of Ophthalmology, Memphis, June 9, 2000. 32. Parker TA, Iannaccone A. Correlation between Goldmann visual field size and maximal ERG response in
patients with Usher syndrome. Alumni and Residents Day, Coleman Building, University of Memphis, UT
Department of Ophthalmology, Memphis, June 9, 2000. 33. Lyubarsky A, Lem J, Chen J, Falsini B, Iannaccone A, Pugh EN, Jr. Functionally rodless mice: Transgenic
models for the investigation of cone function in retinal disease and therapy. Fifth Annual Vision Research
Conference, Animal Models of Retinal Degeneration: New Approaches and Applications. Ft. Lauderdale, FL,
April 27-28, 2001. 34. Iannaccone A, Yashar BM, Ciccarelli ML, Gasparri V, Baldi A, Jablonski MM, Sieving PA. Clinical and
functional findings in patients with X-linked juvenile retinoschisis associated with missense mutations in the
XLRS1 gene. XIII Biannual Meeting of the International Society for Genetic Eye Disease (ISGED), Double
Tree Ocean Front Hotel, Ft. Lauderdale, FL, May 4, 2001. 35. Iannaccone A, Ciccarelli ML, Orten DJ, Weston MD, Baldi A, Jablonski MM, Kimberling WJ. Kinetics of
visual field loss in Usher syndrome type 2. Alumni and Residents Day, Coleman Building, University of
Tennessee HSC, Department of Ophthalmology, Memphis, May 11, 2001. 36. Iannaccone A, Ciccarelli ML, Orten DJ, Weston MD, Baldi A, Jablonski MM, Kimberling WJ. Patterns of
visual function loss in Usher syndrome type 2. 39th ISCEV Symposium, Montréal-Mt. Orford, Canada, June
17-22, 2001. 37. Iannaccone A. X-linked pseudo-Usher syndrome due to mutations in the RPGR gene: A newly recognized
clinical entity. Alumni and Residents Day, Fogelman Executive Center, University of Memphis, Memphis, April
26, 2002. 38. Iannaccone A. Emerging issues in age-related macular degeneration. 6th Annual Clinical Update for the
Comprehensive Ophthalmologist, Peabody Hotel, Memphis, TN, December 7, 2002.
39. Iannaccone A. Disease Spectrum of X-linked Juvenile Retinoschisis: Clinical and Functional Findings. 32nd
Annual UTHSC Ophthalmology Alumni-Residents Day, Fogelman Executive Center, Memphis, TN, April 25, 2003.
40. Iannaccone A. Syndromic Eye Disease. 7th Annual Clinical Update for the Comprehensive Ophthalmologist,
Fogelman Executive Center, Memphis, TN, December 6, 2003.
41. Iannaccone A. Epidemiology of Age-Related Eye Disease in the Mid-South. 8th Annual Clinical Update for
the Comprehensive Ophthalmologist, Fogelman Executive Center, Memphis, TN, December 4, 2004.
42. Iannaccone A. Defining the role of inflammation in AMD. 9th Annual Clinical Update for the Comprehensive
Ophthalmologist, Freeman Auditorium, Hamilton Eye Institute, Memphis, TN, December 3, 2005.
Alessandro Iannaccone, MD, MS, FARVO – Curriculum Vitae – Page 35 of 35
43. Iannaccone A. Longitudinal Measurements of Visual Function in Usher Syndrome Type II. First
International Symposium on Usher Syndrome and Related Disorders, Dr. William J. Kimberling and Dr.
Claes Möller, co-organizers, Boys Town National Research Hospital, Omaha, NE, October 3-6, 2006. 44. Iannaccone A. Role of Autoimmunity in Retinal Diseases. 13th Annual Clinical Update for the Comprehensive
Ophthalmologist, Freeman Auditorium, Hamilton Eye Institute, Memphis, TN, December 5, 2009.
45. Iannaccone A. Update on Treatment Options for Patients with Retinal Degenerative Diseases. 14th Annual
Clinical Update for the Comprehensive Ophthalmologist, Freeman Auditorium, Hamilton Eye Institute,
Memphis, TN, December 11, 2010. 46. Iannaccone A. The Era of Molecular Ophthalmology: Why Getting Your Patient Genotyped Matters. 15th
Annual Clinical Update for the Comprehensive Ophthalmologist, Freeman Auditorium, Hamilton Eye Institute,
Memphis, TN, December 10, 2011. 47. Iannaccone A. The Era of Molecular Ophthalmology: Update on the Valproic Acid Clinical Trial for
Dominant Retinitis Pigmentosa. 16th Annual Clinical Update for the Comprehensive Ophthalmologist,
Freeman Auditorium, Hamilton Eye Institute, Memphis, TN, December 8, 2012. 48. Iannaccone A. The new Center for Retinal Degenerations and Ophthalmic Genetic Diseases at Duke:
Changing the landscape of hereditary blindness. Duke Eye Center Advisory Board Meeting, Hudson