Melanie Swan MS Futures Group +1-650-681-9482 @LaBlogga, @DIYgenomics www.MelanieSwan.com [email protected]March 31, 2012, Sunnyvale CA Slides: http://slideshare.net/LaBlogga Image credit: Natasha Vita-More, Primo Posthuman Elements of a Principia Posthuman Human Body 2.0 Redesign, Democracy, and Next-generation Intelligence
Elements of a Principia PosthumanHuman Body 2.0 Redesign, Democracy, and Next-generation Intelligence
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Human Body 2.0 Redesign, Democracy, and Next-generation Intelligence
March 31, 2012Principia Posthuman 2
About Melanie Swan
Founder DIYgenomics, futurist and applied genomics expert
Current projects: MelanieSwan.com Education: MBA Finance, Wharton; BA
French/Economics, Georgetown Univ Work experience: Fidelity, JP Morgan, iPass,
RHK/Ovum, Arthur Andersen Sample publications:
Source: http://melanieswan.com/publications.htm
Swan, M. Crowdsourced Health Research Studies: An Important Emerging Complement to Clinical Trials in the Public Health Research Ecosystem. J Med Internet Res 2012, Mar;14(2):e46.
Swan, M. Scaling crowdsourced health studies: the emergence of a new form of contract research organization. Personalized Medicine 2012, Mar;9(2):223-234.
Swan, M. Steady advance of stem cell therapies. Rejuvenation Res 2011, Dec;14(6):699-704. Swan, M., Hathaway, K., Hogg, C., McCauley, R., Vollrath, A. Citizen science genomics as a model for
crowdsourced preventive medicine research. J Participat Med 2010, Dec 23; 2:e20. Swan, M. Multigenic Condition Risk Assessment in Direct-to-Consumer Genomic Services. Genet Med
2010, May;12(5):279-88. Swan, M. Emerging patient-driven health care models: an examination of health social networks,
consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009, 2, 492-525.
March 31, 2012Principia Posthuman 3
CONTACT presentations
Data Visualization in Second Life (2008)
Future of Life Sciences: the Great Convergence of Life and Technology (2009)
Revolutionizing Biology with Personal Genomes (2010)
Principia Posthuman (2012)
Slides: http://slideshare.net/LaBloggaImage credit: Natasha Vita-More, Primo Posthuman
March 31, 2012Principia Posthuman
The future is notoriously hard to predict
4
Positional nanoassembly
Young lady’s illustrated primer
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Simple models for thinking about the future
Past Present Future
Image: http://www.sydmead.com
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The role of time in thinking:GPS for the Mind exercise
Plot time orientation: certainty, possibility, probability www.mindtimemaps.com/start/contact
Image: http://www.mindtime.com
Source: Fortunato, VJ and Furey, JT. The theory of MindTime: The relationships between Future, Past, and Present thinking and psychological well-being and distress. Personality and Individual Differences. January 2011, 50(1), pp. 20-4. http://www.miindtime.com
certainty possibility
probability
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GPS for the Mind exercise
CONTACT GPS for the Mind exercise (4 minutes)
1. Sign up for a free account at www.mindtimemaps.com (use an anonymous name if you prefer)
2. Complete the GPS for the Mind exercise at the community site: www.mindtimemaps.com/start/contact
3. Results: return to the community site www.mindtimemaps.com/start/contact and click on the Groups icon, then CONTACT to see the results
Whole organ decellularization and recellularization (heart)
Organ regeneration (urethra)
DNA nanotechnology latch box for drug delivery
Image credit: Aarhus University
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Agenda
Context for Principia Posthuman Elements of a Principia Posthuman
Quantitative: science, human body 2.0 redesign Qualitative: social constructs, democracy Concepts: philosophy, next-generation
intelligence
Conclusion
March 31, 2012Principia Posthuman
Agency: collective intelligence computing
18
Crowdsourcing
Quantified self-tracking
DIYbio labs
Consumer blood tests
Citizen science
Concierge research
Consumer genomics
Health 2.0:Crowdsourced
health computing
Ambient mental performance optimization
Continuous sampling
March 31, 2012Principia Posthuman
Mobile is the platform
Explosive growth US: more cell phones (328 m) than people (315 m)1
One billion+ worldwide smartphone users by 20132
App downloads: 5 bn in 2010 versus 300 mn in 20094
Health-related apps: 7,0004
81% physicians using smartphones 20123
Studies: thousands recruited in months2
Intimate continuous interaction platform Phone loss noticed within 5 minutes vs. 1 hour for wallet loss Kids chat with Siri as virtual friend
19
1Kang C. Number of cell phones exceeds US population. Washington Post. October 11, 2011.2Dufau S. Smart phone, smart science: how the use of smartphones can revolutionize research in cognitive science. PLoS One. 2011.3Kiser K. 25 ways to use your smartphone. Physicians share their favorite uses and apps. Minn Med. 2011. 4Boulos MN. How smartphones are changing the face of mobile and participatory healthcare. Biomed Eng Online. 2011.
Image credit: http://www.psfk.com
Image credit: tehgaygeek.blogspot.com
March 31, 2012Principia Posthuman
Participatory health activity landscape
20
(Light) Level of Engagement (Intense)
Social media
Mobile health apps
PHRs (personal
health records)
Consumer genomics
Image credit: Getty Images
DIYbio (do-it-yourself
biology)
Quantified self-tracking
Citizen science
March 31, 2012Principia Posthuman
DIYbio (do-it-yourself
biology)
Concepts in participatory health
21
Quantified self-tracking
Citizen science
http://ezramagazine.cornell.edu
http://www.iab.keio.ac.jp
http://thecoolgadgets.com
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Citizen science definition
Institutional science research
Citizen science health and biology
Citizen science: 200+ organizations1
1http://scienceforcitizens.net/finder
Performing scientific investigation without professional training in the field Image credit: http://www.southernfriedscience.com
March 31, 2012Principia Posthuman
Citizen science health – why now?
Tools Plummeting cost of genome sequencing Availability of consumer blood tests Online bioinformatics tools
Education and support Local DIYbio labs, online forums
Source: Extended from Swan, M. Emerging patient-driven health care models: an examination of health social networks, consumer personalized medicine and quantified self-tracking. Int. J. Environ. Res. Public Health 2009, 2, 492-525.
Health collaboration communities
Health social networks
(global & local)
March 31, 2012Principia Posthuman
Agenda
Context for Principia Posthuman Elements of a Principia Posthuman
Quantitative: science, human body 2.0 redesign Qualitative: social constructs, democracy Concepts: philosophy, next-generation
Towards an epistemology of citizen science Provide a structure and context for participant-derived health
knowledge
Q1: Are new kinds of knowledge are being formed through group collaborations such as wikipedia and health social networks?
Q2: How to characterize the knowledge generated by traditional medicine, self-experimentation, and health collaboration communities?
Image credit: http://inkingrey.com
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Ontological shift
Old thinking:
My health is the responsibility of my physician
New thinking:
My health is my responsibility
… and I have the tools to make managing it easy
Image credit: http://efx3.com
March 31, 2012Principia Posthuman
Genome politics and regulation
Our world is not Gattaca Personal genomics has
destigmatized health issues
Issues: human cloning, sex selection, genetic privacy, non-discrimination UN Convention on Human Rights and
Biomedicine 1997 (Ch IV Human Genome) U.S. Genetic Information Nondiscrimination
Act (GINA) 2008
Biocitizenry, health as a human right
Image credit: http://www.sonypictures.com
Image credit: http://sciencephoto.com
30
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Role of participative health: future medicine
Individual
2. Peer collaboration and health advisors
Health social networks, crowdsourced studies, health advisors, wellness coaches, preventive care plans,
boutique physicians, genetics coaches, aestheticians, medical tourism
3. Public health systemDeep expertise of traditional health system
for disease and trauma treatment
1. Continuous health information climate Automated digital health monitoring, self-tracking devices, and mobile apps providing personalized recommendations
Source: Extended from Swan, M. Emerging patient-driven health care models: an examination of health social networks, consumer personalized medicine and quantified self-tracking. Int. J. Environ. Res. Public Health 2009, 2, 492-525.
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Health self-management
Source: Extended from Swan, M. Emerging patient-driven health care models: an examination of health social networks, consumer personalized medicine and quantified self-tracking. Int. J. Environ. Res. Public Health 2009, 2, 492-525, Figure 1.
A new model of health and health care
March 31, 2012Principia Posthuman
Biotechnicity and computational philosophy
33
Computational tools of health-related philosophical discovery •Hardware and software devices and algorithms: quantitative health data streams, health-related smartphone applications, personal electronic health records, quantified self-tracking devices •Crowdsourced human computing networks: crowdsourced disease prediction, health social networks, quantified self n=1 health self-experimentation, crowdsourced health research studies, DIYbio labs
Epistemic advance: new knowledge generation•Content: New data streams, larger data sets, more granular data, higher order magnitude science•Process: New algorithms and new models
Metaphysical shift: new ways of being •Meaning of health and health outcomes•Sense of self and group identity, biocitizenry
Source: Swan, M. Biotechnicity 2.0: Computation-enabled Philosophical Advance in the Epistemology of Human Biology and the Ontology of Bioidentity. 2012. Submitted.
Image credit: http://stemcellresources.org
Concepts
Qualitative
Quantitative
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Agenda
Context for Principia Posthuman Elements of a Principia Posthuman
Quantitative: science, human body 2.0 redesign Qualitative: social constructs, democracy Concepts: philosophy, next-generation
intelligence
Conclusion
March 31, 2012Principia Posthuman 35
GPS for the Mind exercise
CONTACT GPS for the Mind exercise (4 minutes)
1. Sign up for a free account at www.mindtimemaps.com (use an anonymous name if you prefer)
2. Complete the GPS for the Mind exercise at the community site: www.mindtimemaps.com/start/contact
3. Results: return to the community site www.mindtimemaps.com/start/contact and click on the Groups icon, then CONTACT to see the results