Previously Bio308 potheses for molecular basis of bipolar disorder •Suggest problem lies in protein targeting How are proteins targeted and delivered? places proteins in membrane and in lumen of organe other) proteins use Sec or SRP mediated translocat come inserted into the ER (and only the ER) nsertion non-ER proteins are sorted and delivered rting lumenal vs membrane proteins –how? http://www.udel.edu/Biology/Wags/histopage/empage/ebv/ebv10.gif
Previously Bio308. Hypotheses for molecular basis of bipolar disorder Suggest problem lies in protein targeting How are proteins targeted and delivered?. Sorting places proteins in membrane and in lumen of organelles. PM (and other) proteins use Sec or SRP mediated translocation to - PowerPoint PPT Presentation
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Transcript
Previously Bio308
Hypotheses for molecular basis of bipolar disorder•Suggest problem lies in protein targetingHow are proteins targeted and delivered?
Sorting places proteins in membrane and in lumen of organelles
PM (and other) proteins use Sec or SRP mediated translocation tobecome inserted into the ER (and only the ER)
After insertion non-ER proteins are sorted and deliveredsorting lumenal vs membrane proteins –how?