CASE STUDY Pressure Ulcer, BKA, Buerger’s Disease Thomas O. Shannon, MD PATIENT: 33 year old Caucasian male WOUND HISTORY: Right below-knee amputation several years ago resulting from Buerger’s Disease. The patient began developing pressure ulcers more than 10 months prior to treatment with TransCu O 2™. CO-MORBIDITIES: Buerger’s Disease (thromboangiitis obliterans) and a history of smoking. PREVIOUS TREATMENTS: Multiple courses of intravenous antibiotics and two failed full-thickness skin grafts. TREATMENT: The patient was treated continuously with low-dose tissue oxygenation using the TransCu O2™ at a setting of 10 ml/hr. After 14 days of low-dose tissue oxygenation with the TransCu O2™, a third full-thickness graft was placed. Below is a series of pictures showing the sequence of healing from initial application of the TransCu O2™ (Day 0) through to near complete healing (Day 95). Patient has regained full mobility with the use of his prosthesis. (Pictures courtesy of Dr. Thomas Shannon, M.D., Houston, Texas and Kim Sims, South Texas Medical Supply, Tomball, Texas) Day 0 – Failed full-thickness skin graft prior to application of TransCu O2™. Day 0 – Wound prepared using debridement and jet lavage. The wound was covered with a non-adherent layer (Conformant™29 and further covered with moisture absorbent dressings The TransCu O2™ Wound Cannula was then applied and covered with an occlusive layer (Tegaderm™) to prepare the wound bed for a full-thickness skin graft. Original wound size was 13 cm x 6.5 cm. Day 14 – Wound after 14 days of continuous oxygen diffusion treatment at 10 ml/hr with the TransCu O2™. Granulation tissue and vascularization were notably increased. Copyrighted 2011 Case Study Confidential Do Not Redistribute Without Written Permission From Electrochemical Oxygen Concepts, Inc. 12500 Network Blvd. Suite 310 San Antonio, Texas 78249 (210)-338-7300 690022 rev0611