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Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor of Graduate Biostatistics Drexel University College of Nursing and Health Professions Philadelphia, PA © ICHE J.Ruggiero, PhD. 2009
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Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

Jan 28, 2016

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Page 1: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

Presented byJohn Ruggiero, MPA, PhD

Vice President, Education and OutcomesInstitute for Continuing Healthcare Education

Philadelphia, PA

Adjunct Professor of Graduate BiostatisticsDrexel University

College of Nursing and Health ProfessionsPhiladelphia, PA

© ICHE J.Ruggiero, PhD. 2009

Page 2: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

Disclosures

John Ruggiero has no interest in selling technology, a program, product, and/or service to CME professionals. There are no

financial disclosures to report.

Page 3: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

STATISTICS?! WHY SHOULD I BE INTERESTED IN THAT? Statistics create order from chaos Statistics empower one to consider and

complete the larger picture Statistics help us become better citizens Statistics create outcomes—historical

reports that evoke decisions

Page 4: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

A BIT OF HISTORY

Page 5: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

THE REALITY

Every person in an organization should understand his/her individual and organizational expected goal(s) for success.

The information should be used to measure and improve effectiveness.

Page 6: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

LEARNING OBJECTIVES

At the end of this lecture, learners should be

able to:

1. Generally explain the terminology used with statistics

2. Analyze the information presented3. Discern the relevant information

from the irrelevant information

Page 7: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

KEY COMPONENTS TO A STUDY Population ( µ ) v. Sample ( x ) Collection of Data Independent variable v. Dependent

variableExample: Correlation between education

and a commitment-to-change performance

Page 8: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

DESIGNING A STUDY

DESCRIPTIVE STATISTICSDescribing a situation –

The collection of data occurs before the analysis

INFERENTIAL STATISTICSHypotheses describe a situation – The researcher makes educated

guesses, collects the data and then analyses whether or not the hypotheses were correct

Page 9: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

SAMPLING: HOW TO GET THE DATA Random Sampling

Samples are chosen without rhyme or reason Systematic Sampling

Samples are chosen by every kth number Stratified Sampling

Samples are divided into groups and then randomly chosen from those groups

Clustered SamplingSamples are chosen from a specific cluster for

purposes of the study design

Page 10: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

MAKING OBSERVATIONS Collect the data

○ Rating learning objectives○ Rating faculty○ Was the education fair and balanced?

Measure your Central Tendency and DispersionMean, Median, and ModeStandard Deviation

Page 11: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

EXAMPLE 1

Using a scale of 1-4 (ORDINAL DATA):1. Learning Objective was not met

2. Learning Objective was partially met

3. Learning Objective was met

4. Learning Objective exceeded expectations

The mean of learning objective 1 is collected among 10 learners from a small regional dinner activity

Page 12: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.
Page 13: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

EXAMPLE 1 ANALYSIS Using a scale of 1-4 (ORDINAL DATA):

1. Learning Objective was not met

2. Learning Objective was partially met

3. Learning Objective was met

4. Learning Objective exceeded expectations

At a mean of “3”, learners from this activity believed that Learning Objective 1 was met. The margin of error is (±1.247).

Page 14: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

OBJ 1

0

5

10

15

20

1 2 3 4

OBJ 1

Page 15: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

70%

10%

0%

20%Physicians

Nurses

Pharmacists

Other

Page 16: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

HISTOGRAMS

A histogram, or normal distribution curve, is used to graphically represent the normalcy of the mean related to all other data values from a study

ENGLISH!

Page 17: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

Most of your data centers around the

mean

Extraneous data falls here

Page 18: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

Histogram on Practice Change

02468

1012

1 2 3 4

Bins

Series1

Page 19: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

DOSE OF REALITY

Pretty charts, animated graphs, and clean presentations don’t mean a thing, unless…You measure the results against a previous

educated guessThe study can be repeated

Page 20: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

HYPOTHESES:THE EDUCATED GUESS Alternate v. Null

H1 (Alternate)○ The research hypothesis○ An observed effect is genuine – there is a

definite change

H0 (Null)○ There is no change to the study

Page 21: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

HYPOTHESES EXAMPLE (Figures are fictitious). Let’s assume that the

national mean for victims of domestic violence is reported at 7%. This can be assumed because a cluster sample of 1500 people who had entered a medical facility emergency room in the past 12 months was completed.

My educated guess is that 7% is too low. I therefore believe that after educating targeted emergency room medical staff, and agreeing that every patient (regardless of visitation cause) is directly asked if they are a victim of domestic violence, the national mean will increase.

Page 22: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

HYPOTHESES EXAMPLE Cont’d H0 (Null)

µ = 7%

H1 (Alternate)µ ≠ 7%

This is a two-tailed testRule of thumb: When hypotheses are written

with equality statements (= to) a two-tailed test can be assumed. When hypotheses are written with inequality statements (>,<) a one-tailed test can be assumed.

Page 23: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

HYPOTHESES TESTING Declare an alpha (α) level of significance

○ Usually .01, .05 or .10○ This becomes known as the Critical Value○ Critical Value is compared to the z table. z-score

is then identified Recognize the p-value

○ The probability of getting values of the test statistic as extreme, or more extreme than, that observed if the null is true.

Statistical Significance○ If the p-value is less than the alpha, or when

completing a test value, the value falls within the Critical Value (beyond the z-score), one rejects the null hypothesis

Page 24: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

P-value is = .05 while the observed value is 1.645. If the result is greater than 1.645, or in the critical region (5%), then you reject the null.

Page 25: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

RELATING HYPOTHESES TO THE CME INDUSTRY

How could you use alternate and null hypotheses to assist you with one of your CME initiatives?

Page 26: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

CONFIDENCE INTERVALS

Can the study be repeated at a specific level of confidence?Statisticians will usually choose either 99%,

95%, or 90% confidence percentages○ Example: If you claim 95% confidence with

your results, you are basically saying that no matter how many times you repeat a study, 95% of the time the mean and all other results will be similar.

Why this is important for CME

Page 27: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

CONFIDENCE INTERVAL TESTS CI Test of the Means

○ (n > or = 30)

T-test ○ (n < or = 29)

Page 28: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.
Page 29: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

CORRELATION & REGRESSION Correlation is the association between

two quantitative variables Association is linear The correlation coefficient is measured

on a scale that varies from + 1 to -1. Symbol for correlation is r

Page 30: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

Correlation Graphs

Le, C.T. (2001).

Page 31: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

Correlation Example

Le, C.T. (2001).

Page 32: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

Regression (The Trend)

Ruggiero, J. based on Le, C.T. (2001).

Page 33: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

LOOK FAMILIAR?

Page 34: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

Survival Curves Survival curves illustrate prognosis. The

percentage of patients reaching an endpoint (for example: death, recurrence of disease, or cure) is plotted on the y (vertical) axis against time on the x (horizontal) axis.

The Kaplan-Meier method is preferred unless there is an extremely large number of patients being studied

Page 35: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.
Page 36: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

MISUSES OF STATISTICS

Loaded-questions Self-interest Precise numbers Voluntary response

Page 37: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

APLLICABLE TO CME? Yes For professionals, statistics can be

considered the science ofCollecting dataSummarizing dataDrawing practical conclusions

Statistics assist with Outcomes Measurements

Tracking Change in Practice and Behavior Tracking Change in Knowlegde

Page 38: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

Resources Le, C.T. (2001). Health & numbers: A problems-based

introduction to biostatistics. (2nd Edition). NY: Wiley-Liss.

Levine, David M., Mark L Berenson, David Stephan. (1999) Statistics for managers: using Microsoft Excel. Upper Saddle River, New Jersey. Prentice-Hall

Motulsky, Harvey. (1995) Intuitive biostatistics. Oxford University Press Inc.

Patten, Mildred L. (2002). Understanding research methods: An Overview of the essentials (3rd ed.). Los Angeles: Pyrczak Publishing.

Swinscow, TDV. (2006). Statistics at square one. Ninth edition. BMJ Publishing Group.

Page 39: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

QUESTIONS?

Page 40: Presented by John Ruggiero, MPA, PhD Vice President, Education and Outcomes Institute for Continuing Healthcare Education Philadelphia, PA Adjunct Professor.

THANK YOU

John Ruggiero, MPA, PhD

E-mail: [email protected]

TEL: (215) 446-8088

ext 1440