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Herpetic Keratitis
Other names :
viral conjunctivitis
acute hemorrhagic conjunctivitis (AHC)
herpes conjunctivitis
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It is a self- limiting infection ofthe eyelids, conjunctiva andcornea due to viral invasion.
It often results in deep ulcersand may be one of the mostcommon cause of blindness inthe United States. It usually lastsfor 1-3 weeks.
Herpetic Keratitis
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Once herpes simplex is present in the eye, it
typically infects the eyelids, conjunctiva (thethin, filmy, mucous membrane that coversthe inside of the eyelids and the white partof the eye) and cornea (the clear, frontwindow of the eye).
It may also infect the inside of the eye;however, this is much less common.
It is acquired via person-to-person contactwith infected eye secretions.
Herpetic Keratitis
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The Human Eye
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The Causative Agent
Herpes simplex type I
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HSV I
General Characteristics:
*Spherical,
*Measures 120-200nm
diameter
*Double stranded DNA withprotein coat havingicosahedral symmetry.
*Enveloped neucleocapsid.
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Symptoms of Herpetic keratitis
Corneal inflammation
Red eye
Eye irritation
Reduced visual acuity Eye pain
Eye tearing
Light sensitivity
http://www.rightdiagnosis.com/sym/corneal_inflammation.htmhttp://www.rightdiagnosis.com/sym/red_eye.htmhttp://www.rightdiagnosis.com/sym/eye_irritation.htmhttp://www.rightdiagnosis.com/sym/vision_loss.htmhttp://www.rightdiagnosis.com/sym/eye_pain.htmhttp://www.rightdiagnosis.com/sym/photophobia.htmhttp://www.rightdiagnosis.com/sym/photophobia.htmhttp://www.rightdiagnosis.com/sym/eye_pain.htmhttp://www.rightdiagnosis.com/sym/vision_loss.htmhttp://www.rightdiagnosis.com/sym/eye_irritation.htmhttp://www.rightdiagnosis.com/sym/red_eye.htmhttp://www.rightdiagnosis.com/sym/corneal_inflammation.htm8/3/2019 Presentation Micro Bio
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Prevention and Control:
Personal hygiene;
drainage precautions;
strict asepsis in eye clinics
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The list of treatments mentioned invarious sources forHerpetickeratitis includes the following list.Always seek professional medical
advice about any treatment orchange in treatment plans.
Treatment of HSV Infections
1-2% trifluridine1% iododeoxyuridine
3% vidarabine
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Herpetic Keratitis
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Acanthamoeba keratitis
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Acanthamoeba
Keratitis
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Acanthamoeba keratitis: Infection of the eye
with a microscopic, free-living ameba(Acanthamoeba) that isreadily found in theenvironment- soil, air and water. Infectionmost often occurs through exposure to
contaminated waterwhilewearing contactlensese.g. swimming or showering in infectedwaters.
It is acquired by swimming in stagnantswimming pools; wearing of contact lensesovernight and while swimming.
Acanthamoeba Keratitis
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It is an infection characterized by the invasion ofa trophozoite into the eyes which on early stageof infection may consist of only mild a mildinflammation but later stages may result insevere pain and cause eye damage and may
complicate to blindness.
Acanthamoeba keratitis is a rare diseasewhere amoebae invade the corneaof the eye.
Acanthamoeba Keratitis
http://en.wikipedia.org/wiki/Rare_diseasehttp://en.wikipedia.org/wiki/Amoebaehttp://en.wikipedia.org/wiki/Corneahttp://en.wikipedia.org/wiki/Human_eyehttp://en.wikipedia.org/wiki/Human_eyehttp://en.wikipedia.org/wiki/Corneahttp://en.wikipedia.org/wiki/Amoebaehttp://en.wikipedia.org/wiki/Rare_disease8/3/2019 Presentation Micro Bio
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Causative agent:
Acanthamoeba spp.
Acanthamoeba KeratitisAcanthamoeba
Phase contrast micrograph of anAcanthamoebapolyphaga cyst.
Scientific classification
Domain: Eukaryota
Kingdom: Amoebozoa
Genus: Acanthamoeba
http://en.wikipedia.org/wiki/File:Acanthamoeba_polyphaga_cyst.jpghttp://en.wikipedia.org/wiki/Biological_classificationhttp://en.wikipedia.org/wiki/Eukaryotahttp://en.wikipedia.org/wiki/Amoebozoahttp://en.wikipedia.org/wiki/File:Acanthamoeba_polyphaga_cyst.jpghttp://en.wikipedia.org/wiki/Amoebozoahttp://en.wikipedia.org/wiki/Eukaryotahttp://en.wikipedia.org/wiki/Biological_classification8/3/2019 Presentation Micro Bio
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Inside the human body
Acanthamoeba
Keratitis
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General Characteristics:
Small, free living amoeba found in stagnant
fresh water, hot tubs, tap water and soil;
Has two developmental stages: trophozoite(Active, motile stage); cyst (Dormant, inactive,nonmotile stage)
Infective stage: Trophozoite
Reproduce by binary fission; encystationswhen environment becomes adverse.
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Life Cycle of Acanthamoeba
Si d S
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Vision impairment
Red eyes Light sensitivity
Severe eye pain
Eyelid swelling Watery eyes
Blurred vision
Sensation of something in eye Excessive tearing
Signs and Symptoms
P ti d C t l
http://www.rightdiagnosis.com/sym/impaired_vision.htmhttp://www.rightdiagnosis.com/sym/red_eye.htmhttp://www.rightdiagnosis.com/sym/photophobia.htmhttp://www.rightdiagnosis.com/sym/eye_pain.htmhttp://www.rightdiagnosis.com/sym/eyelid_swelling.htmhttp://www.rightdiagnosis.com/sym/watery_eye.htmhttp://www.rightdiagnosis.com/sym/blurred_vision.htmhttp://www.rightdiagnosis.com/sym/tear_symptoms.htmhttp://www.rightdiagnosis.com/sym/tear_symptoms.htmhttp://www.rightdiagnosis.com/sym/blurred_vision.htmhttp://www.rightdiagnosis.com/sym/watery_eye.htmhttp://www.rightdiagnosis.com/sym/eyelid_swelling.htmhttp://www.rightdiagnosis.com/sym/eye_pain.htmhttp://www.rightdiagnosis.com/sym/photophobia.htmhttp://www.rightdiagnosis.com/sym/red_eye.htmhttp://www.rightdiagnosis.com/sym/impaired_vision.htm8/3/2019 Presentation Micro Bio
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Avoid swimming in stagnant swimmingpools
Use pre-heated tap water as facial wash
Avoid use of home-made saline solutions
Prevention and Control:
T t t
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Treatment
Topical application to affected eye ofpropamidine isethionate or miconazole
Corneal transplant
Eye removal surgery
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