Predicting visual performance from wavefront quality metrics in cataract Konrad Pesudovs Katja Ullrich NH&MRC Centre for Clinical Eye Research, Flinders Medical Centre & Flinders University, Adelaide, South Australia Financial disclosure: The authors have no financial interest
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Predicting visual performance from wavefront quality metrics in cataract Konrad Pesudovs Katja Ullrich NH&MRC Centre for Clinical Eye Research, Flinders.
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Predicting visual performance from wavefront quality metrics in
cataract
Konrad Pesudovs
Katja UllrichNH&MRC Centre for Clinical Eye Research,
Flinders Medical Centre & Flinders University, Adelaide, South Australia
Financial disclosure: The authors have no financial interest
Background and Purpose• Cataract affects visual performance via higher order
aberrations and light scatter• Wavefront aberrations occurring in cataract have been
described in terms of the Zernike polynomial decomposition but neither Zernike terms nor RMS predict visual performance
• Other methods for organising wavefront data exist – wavefront quality metrics
• Attempts to connect wavefront quality metrics to visual performance in cataract are lacking
PURPOSE: To determine which wavefront quality metrics are most predictive of visual performance in patients with cataract
Population and Visual Performance
• Prospective, cross-sectional study of consecutive patients attending the Cataract Assessment Clinic at Flinders Medical Centre
• Wavefront data exported to VOLPro software v7.25 (Sarver and Associates) and 10th order Zernike expansion derived
• Zernike data exported to GetMetrics v.2.02.006 (University of Houston, College of Optometry) by Thibos and Applegate for calculation of wavefront quality metrics
• 31 metrics of wavefront quality designed to be predictive of visual performance were calculated for the pupil plane and the image plane as per: Thibos LN, Hong X, Bradley A, Applegate RA. Accuracy and precision of objective refraction from wavefront aberrations. J Vis 2004;4(4):329-51.
• Linear Regression with SPSS Software V15.0 (SPSS Inc)
Results - visual acuity and wavefront quality metrics
• Visual acuity and logPFWc, r2=-0.37, p<0.001
• The strongest correlate of all three measures of visual performance was the pupil fraction metric PFWc
Results – contrast sensitivity and wavefront quality metrics
• Pelli-Robson contrast sensitivity and logPFWc, r2=0.39, p<0.001