9/22/2015 1 by Scott Cerreta, BS, RRT Director of Education www.copdfoundation.org [email protected]Understanding COPD - Recent Research and the Evolving Definition of COPD for MNACVPR CONFLICT OF INTEREST • I have no financial conflict of interest that relates to this presentation. Any use of brand names is not in any way meant to be an endorsement of a specific product, but to merely illustrate a point of emphasis. OBJECTIVES 1. Discuss current literature and research that warrants the need to change COPD definitions and guidelines. 2. Describe current research that challenges the current definition of COPD today and treating patients with seven severity domains. 3. Describe concepts of mild-COPD, early-COPD and pre-COPD. 4. Identify how these changes will someday impact future diagnosis and treatment recommendations.
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PowerPoint Presentation...9/22/2015 2 NHLBI DEFINITION • Chronic Obstructive Pulmonary Disease • Serious lung disease that over time makes it hard to breathe • Emphysema •
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Understanding COPD - Recent Research and the Evolving Definition of COPD
for MNACVPR
CONFLICT OF INTEREST
• I have no financial conflict of interest that relates to this presentation. Any use of brand names is not in any way meant to be an endorsement of a specific product, but to merely illustrate a point of emphasis.
OBJECTIVES
1. Discuss current literature and research that warrants the need to change COPD definitions and guidelines.
2. Describe current research that challenges the current definition of COPD today and treating patients with seven severity domains.
3. Describe concepts of mild-COPD, early-COPD and pre-COPD.
4. Identify how these changes will someday impact future diagnosis and treatment recommendations.
• Are there different types of COPD • Using HRCT and identified a large
number of people with emphysema despite normal spirometry
• 10,300 subjects
• Spiromics – Dr Rennard
• Identifying subsets of people with COPD
• Why do some COPD patients respond to treatment while others do not?
• Collection & analysis of phenotypic, biomarker, genetic, genomic, and clinical data from subjects with COPD
• 3,200 subjects
COPDGENE
• At least 10 pack-years of cigarette smoking
• Spirometry that meets one of four Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages or normal (FEV1 greater than 80% of predicted level and forced expiratory volume in 1 second/forced vital capacity [FEV1/FVC] greater than 0.7)
• No Grade U
• Self-designation of non-Hispanic white or African-American
Despite being the third leading cause of death in the United States, there is very little funding for COPD. COPD is presentable and treatable but the lack of research,
awareness and education has resulted in millions of unnecessary hospitalizations, complications and deaths.
PATIENT CENTERED OUTCOMES RESEARCH INSTITUTE
• Independent research organization authorized by Congress as part of the 2010 Patient Protection and Affordable Care Act • Fund comparative clinical effectiveness research that provides patients and their caregivers the information they need to make better informed health care decisions
COPD FOUNDATION PCORI PROJECTS
PELICAN: comparative effectiveness of a PEer-Led O2 Infoline for patients and CAregivers - evaluate whether a peer-led O2 infoline for patients and caregivers will increase adherence to oxygen prescription and improve health in patients with COPD discharged from the hospital with an oxygen prescription
PArTNER: PATient Navigator to rEduce Readmissions - focuses on developing and testing a program that combines a community health worker (lay patient advocate, acting as a "Patient Navigator") and a peer-led telephone support line to increase social support, improve self-efficacy and decrease post-discharge acute care use. ClinicalTrials.gov
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PELICAN FLIER
• We need your help
• Oxygen coaching
• Anyone with 24/7 oxygen use
• Be part of the future discoveries in COPD through research
“You might have lost your breath, but you haven’t lost your voice”
Empowering Patients through Research
COPD360SOCIAL & INFOLINE
9/22/2015
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More patient focused COPD
research is the answer to
finding more effective therapies
and eventually cures to help the
millions of COPD patients.
“After registering I felt
as though I was a part
of a major breakthrough
for COPD.”
“By joining the COPD
PPRN we have nothing
to lose and everything to
gain.”
“Registering for the PPRN is an opportunity for
me to contribute to the body of research that
may make the key discovery that leads to the
cure. Being a part of this program is very
empowering and makes me feel like I’m doing
my part to help.”
YOU CAN HELP !
• Request postcards to share at support groups, clinics, respirator care departments, etc
• Posters and paper surveys available for some locations.
• www.copdpprn.org
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SUMMARY
1. Implications for treatment of COPD is ever evolving based on the evidence.
2. COPD is involved with several studies and has many programs to improve quality of life for people living with COPD.
3. LDCT lung cancer screening is a win for lung health and COPD early dx.
4. Patients have the power in finding cures. Join the Patient Powered Research Network (PPRN).