Pooled Analysis of Trials Pooled Analysis of Trials Comparing Titanium Nitride Comparing Titanium Nitride Oxide Coated Stents with Oxide Coated Stents with Paclitaxel Eluting Stents Paclitaxel Eluting Stents in Patients Undergoing PCI in Patients Undergoing PCI Otto M. Hess Otto M. Hess Swiss Cardiovascular Center Swiss Cardiovascular Center University Hospital, Bern University Hospital, Bern otto.hess @ insel.ch otto.hess @ insel.ch
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Pooled Analysis of Trials Comparing Titanium Nitride Oxide Coated Stents with Paclitaxel Eluting Stents in Patients Undergoing PCI Otto M. Hess Swiss Cardiovascular.
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Pooled Analysis of Trials Pooled Analysis of Trials Comparing Titanium Nitride Oxide Comparing Titanium Nitride Oxide
Coated Stents with Paclitaxel Coated Stents with Paclitaxel Eluting Stents in Patients Eluting Stents in Patients
Undergoing PCIUndergoing PCI
Otto M. HessOtto M. Hess
Swiss Cardiovascular CenterSwiss Cardiovascular Center
University Hospital, BernUniversity Hospital, Bern
otto.hess @ insel.chotto.hess @ insel.ch
Conflict of Interest Conflict of Interest StatementStatement
Clinical outcome in the propensity-Clinical outcome in the propensity-score-matched groupsscore-matched groups
ConclusionsConclusions1. Titanium-coated stents show a similar safety
and efficiency as DES of the first generation over 3 years suggesting no benefit of first generation drug eluting stents over Titanium-coated stents
2. Stent thrombosis rates are low for all 3 stent types but are lowest for Titanium-coated stents. However, dual antiplatelet therapy was carried out only for 3 months in Titanium-coated and 12 months in drug-eluting stents
3. Thus, bio-active stents are a true alternative to DES of the first generation specifically in patients with an increased bleeding risk and in elderly.