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The risk of fetal death innonanomalous pregnancies aectedby polyhydramnios
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PHYSIOLOGY OF AMNIOTIC FLUID Early pregnancy: composition of AF
similar to ECF. Transfr of !atr across
amnion an" t#ro$%# ftal s&in.
By second trimester: ft$s '%ins to
$rinat s!allo!( an" inspir AF D$rin% last )*+of pr%nanc,( AF is principall, compris" of ftal$rin.
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NORMAL AMNIOTIC FLUID VOLUMENORMAL AMNIOTIC FLUID VOLUME
WeeksGestation
Fetus Amniotic Fluid Placenta!" ml" !"
16
28
36
40
100 200 100
1000 1000 200
2500 900 400
3300 800 500
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DEFINITIONS:
Pol,#,"ramnios- >) cc amniotic /$i"
Amniotic Fl$i" In"0 1 lar%st 2rtical
poc&t in 3 4$a"rants
pol,#,"ramnios >)3 cm.
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Etiology of
olyhydramnios:Fetal !nomalies Pro'lms !it# s!allo!in% an" GI a'sorption
Incras" trans$"ation of /$i"-
anncp#al,( spina 'i5"a Incras" $rination- anncp#al, 6lac& of ADH(
stim$lation of $rination cntrs7
Dcras" inspiration
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"auses of polyhydramnios
Ftal malformation- 8 GIT-
sop#a%al*"$o"nalatrsia(
trac#osop#a%al5st$la.
8 CNS- anncp#al,69s!allo!in%(0pos" mnin%s( noanti"i$rtic #ormon7.
T!in8t!in transf$sion
: ftal pol,$ria.
H,"rops ftalis-con%sti2 #artfail$r( s2r anamiaor #,poprotinmia :
placntal trans$"ation
"ia'ts mllit$s
6osmotic "i$rsis7.
I"iopat#ic.
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olyhydramnios
types
#$ %ild hydramnios &'()*:
a pocket of amniotic +uid measuring ' to ##cm$
,$ moderate hydramnios -)*:
a pocket of amniotic +uid measuring #, to #-cm$
.$ Se/ere hydramnios &-)* 0 t1in0t1intransfusion syndrome :
a pocket of amniotic +uid measuring #2 cm ormore.
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diagnosis of polyhydramnios
S,mptoms-
8 ",spna.8 "ma.8 a'"ominal "istntion
8 prtrm la'o$r.
A'"ominal 0amination-8 ;$tr$s t#an 0pct".8 "i
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SYMPTOMS
D,spna
A'"ominal pain
Contractions prtrm la'or Dcras" Prcption of Ftal
Mo2mnts
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DI!3NOSIS
F$n"al #i%#t = %stationala%
Di>>Sono%rap#,
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6Mot#r7?
D,spna
Placntal a'r$ption
Utrin ",sf$nction
Post8part$m #morr#a%
A'normal prsntation
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6ft$s7?
Ftal pro%nosis !orsns !it# mor s2r#,"ramnios an" con%nital anomalis
@8)B ftal malformations
Prtrm "li2r,
S$spct "ia'ts
Prolaps of cor"
A'r$ption
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s$lt
T# ris& of IUFD in pr%nancis act" ',pol,#,"ramnios !as %ratr at 2r, %stationala% compar" !it# $nact" pr%nancis. T#IUFD ris& in pr%nancis act" ',
pol,#,"ramnios !as mor t#an tims #i%#rt#an $nact" pr%nancis at + !&s
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On%oin% ris& of IUFD is %ratr in lo!8ris&pr%nancis act" ', pol,#,"ramnios at all%stational a%s compar" !it# $nact"pr%nancis !it# t# %ratst incras in ris& at
trm.