Pituitary G land Posterior Lobe

BY: ELENA SEIFERT & KRISTEN THORNEPERIOD 8

1/8 /14

Pituitary Gland Posterior Lobe

Location

Part of the brain

What type of hormones are produced?

ADH (antidiuretic hormone)Oxytocin

How do these hormones affect the body?

ADH- Promotes reabsorption of water by the kidneys

Oxytocin- strongly affects human social interactions, stimulates uterine contractions during childbirth and facilitates breast feeding AKA the “love hormone”

Maintenance of homeostasis

ADH- helps maintain water and electrolyte balance

The pituitary and the hypothalamus glands work together to regulate the release of other hormones in the body.

Feedback Mechanisms

ADH- when there is not enough water in the blood ADH is secreted so the kidneys reabsorb water (negative feedback)

Oxytocin- during childbirth, oxytocin is released to stimulate uterine contraction and lactation from the mammary glands (positive feedback)

Antagonistic Hormones

Vasopressin Receptor Antagonist (VRA)- blocks ADH for those with congestive heart failure

Atosiban (oxytocin receptor antagonist)- blocks Oxytocin to control emotions and hormones

Disorders

With a damaged or malfunctioning pituitary gland, your body would lose the normal ability to regulate the hormones released by most endocrine glands.

Disorders of the posterior pituitary gland are: diabetes insipidus Syndrome of Inappropriate Antidiuretic Hormone

Secretion (SIADH)

Diabetes insipidus

Condition where the kidneys are unable to conserve water due to lack of ADH

Symptoms- Extreme thirst Excessive urine volume

Treatment- Medication (vasopressin)

SIADH

Condition where high levels of ADH cause the kidneys to absorb excessive amounts of water.

Symptoms- Nausea/vomiting Cramping Seizures Coma

Treatment- Surgery to remove the gland releasing ADH Medication to block ADH

Sources

http://someinterestingfacts.net/wp-content/uploads/2012/12/Pituitary-gland.jpg

http://droualb.faculty.mjc.edu/Course%20Materials/Physiology%20101/Chapter%20Notes/Fall%202011/chapter_6%20Fall%202011.htm

http://scientopia.org/blogs/scicurious/2009/11/09/oxytocin-starting-with-the-basics/

http://www.emoryhealthcare.org/pituitary/pituitary-gland.html http://faculty.clintoncc.suny.edu/faculty/michael.gregory/files/bio%20102/bi

o%20102%20lectures/endocrine%20system/endocrin.htm

http://www.frontalpioneer.com/2013/04/adhoxytocinprolactin-podcast.html http://www.drugs.com/drug-class/vasopressin-antagonists.html http://www.lpch.org/DiseaseHealthInfo/HealthLibrary/diabetes/siadh.html http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001415/#

adam_000377.disease.symptoms http://

www.urmc.rochester.edu/Encyclopedia/Content.aspx?ContentTypeID=90&ContentID=P01974