#PittScience2019 Wednesday · Human Metal Contamination: Lessons from Greening the Steel City Emily Elliott, PhD Reactive Nitrogen in Pittsburgh Streams and Fluvial Ecosystems Sarah

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Wednesday 16 OCTOBER

1:00 p.m. Registration location: Alumni Hall Foyer, 1st Floor

2:00–5:00 p.m. Special Symposium: William (Chet) de Groat, PhD — 51 Years as a Pitt Faculty Icon location: Alumni Hall, Room 121, 1st Floor

This symposium at Science 2019 recognizes the unparalleled basic/clinical research advances, teaching, and mentoring that have been provided to the University community by Chet de Groat, PhD, Distinguished Professor of Pharmacology and Chemical Biology. Dr. de Groat officially “retired” in May 2019 but is still publishing important new advances and providing mentorship to his many colleagues—all of whom revere him. Please join us for this celebration of academic excellence and, in particular, the many contributions of this supremely kind and generous person.

introduction: Bruce Freeman, PhD

faculty speakers: Lori Birder, PhD; Naoki Yoshimura, MD, PhD; Jonathan Beckel, PhD

graduate student speakers: Joseph Galley; Matthew Keeney

keynote lecture:

Anthony Ford, PhD Plumbing, Wiring, Hollow Organs, and New Therapeutics

4:00 p.m. Michael G. Wells Entrepreneurial Scholars Lecture

location: Alumni Hall, Auditorium, 7th Floor

This year’s Wells Lecture features a panel of Wells Student Health Care Competition alumni who went on to form startup companies. They will share their experiences behind launching companies from the University and the opportunities and challenges of growing their companies as part of the region’s innovation ecosystem.

panelists:

Joseph Pugar Cofounder and CEO, Aruga Technologies

Lorenzo Soletti, MBA, PhD Cofounder and CEO, Renerva LLC

Eunice Yang, PhD Associate Professor of Mechanical Engineering, Pitt Johnstown Founder, OK2StandUp

panel moderator: Rich Lunak, President and CEO, Innovation Works

William (Chet) de Groat, PhD

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4:45 p.m. Michael G. Wells Student Health Care Competition and Kuzneski Innovation Cup Winner Announcements

location: Alumni Hall, Auditorium, 7th Floorpresenters: Michael G. Wells, MS, MBA;

Andrew and Laurie Kuzneski

The Michael G. Wells Student Health Care Competition brings together University of Pittsburgh students who are developing health care innovations. The competition is sponsored by the Michael G. Wells Entrepreneurial Scholars Fund.

The Kuzneski Innovation Cup, sponsored by local entrepreneurs Andrew and Laurie Kuzneski, involves Pitt students who are developing innovations in fields outside of health care that can improve people’s lives.

Early in the day, student finalists for both competitions will pitch their innovations to judges from the local business community. The winners will be announced before the start of the Innovation Showcase, where all competition participants can share and discuss their innovations.

5:00 p.m. Opening Reception and Innovation Showcase

location: Alumni Hall, J.W. Connolly Ballroom, 1st Floor

Join the University of Pittsburgh Innovation Institute for a first look at the latest Pitt-generated innovations in health care, assistive technologies, Internet of things, information technology, human performance, and more. Many of these technologies are available for licensing, and others already form the basis of local, early-stage companies.

You will have the unique opportunity to network with these inventors and founders, as well as with local entrepreneurs, investors, and community leaders. Don’t miss this opportunity to view novel Pitt discoveries that have already received development funding and mentorship from a host of sources on campus. All Science 2019 registrants are invited to this eagerly anticipated opening reception.

Science2019SCHEDULE

Wednesday 16 OCTOBER

Science 2019 events will take place in Alumni Hall and the William Pitt Union.

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Thursday 17 OCTOBER

8:00 a.m. Registration

location: Alumni Hall Foyer, 1st Floor

9:00 a.m. Spotlight Session 1: Inflammation, Immunology, and Disease location: Alumni Hall, Room 121, 1st Floor

moderator: Mark Shlomchik, MD, PhD

Mark Shlomchik, MD, PhDInnate Immunity and Autoimmunity

Greg M. Delgoffe, PhDFeast and Famine: How Nutrient Availability Affects T-Cell Function

Mandy McGeachy, PhDImmune/Stromal Cell Interactions Energize the Base

Fadi Lakkis, MDImmune Sensing and Memory of Organ Transplants: A Job Not Only for Lymphocytes

Spotlight Session 2: Mapping and Understanding the Brain

location: William Pitt Union, Kurtzman Room, Main Floor

moderator: Sarah Ross, PhD

Peter Strick, PhDA Brain-Body Connection

Afonso Silva, PhDUsing Magnetic Resonance Imaging To Travel Inside the Primate Brain

Shawn Sorrells, PhDAdding New Neurons to the Human Brain during Adolescence

Julie Fiez, PhDThe Reading Brain

Spotlight Session 3: It’s the Only Planet We Have

location: William Pitt Union, Room 548, 5th Floor

moderator: Melissa Bilec, PhD

Daniel Bain, PhDHuman Metal Contamination: Lessons from Greening the Steel City

Emily Elliott, PhD Reactive Nitrogen in Pittsburgh Streams and Fluvial Ecosystems

Sarah Haig, PhDFrom Source to Tap: Linking the Drinking Water Microbiome to Human Health and Beyond

Matthew M. Barry, PhDCleaning Up Sustainable Energy Production—Capturing Wasted Energy To Improve Efficiency

10:30 a.m. Exhibit Break


11:00 a.m. Plenary Session 1: Dickson Prize in Medicine Lecture


welcome: Patrick D. Gallagher, PhD

introduction of speaker: Arthur S. Levine, MD

keynote speaker: Ruslan Medzhitov, PhD Host Defense Strategies

12:30 p.m. Exhibits & Lunch


1:00 p.m. Poster Session 1


• Basic Life Science — From Molecule to Mouse

• Translational Life Science — From Animal to Human to Community

• Physical Science and Engineering

• New Research Tools and Techniques

2:00 p.m. Spotlight Session 4: Harnessing Technologies and Systems To Solve Real-World Problems

location: Alumni Hall, Room 121, 1st Floor

moderator: George Klinzing, PhD

Ryad Benosman, PhDWhat Is Neuromorphic Event-Based Computer Vision? Sensors, Theory, and Applications

Andrew Schwartz, PhDRestoring Movement by Recognizing Brain Signaling

Ron Poropatich, MDTrauma Care in a Rucksack

Christopher Wilmer, PhDA Nose for Robots: Engineering Atomically Precise Arrays of Olfactory Receptors

Thursday 17 OCTOBER

Science2019SCHEDULE


Ruslan Medzhitov, PhD

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2:00 p.m. (cont.) Spotlight Session 5: Cellular and Protein Signaling and Trafficking


Moderator: Peter Drain, PhD

Marijn Ford, PhDUsing Cryo-Electron Microscopy To Catch Old Dogs Doing New Tricks: The Story of the Sorting Nexin Mvp1

Allyson O’Donnell, PhDThe Heart of the Matter: Alpha-Arrestin Regulation of the Cardiac Potassium Channel Kir2.1

Quasar Padiath, MBBS, PhDThe Spatial Organization of the Nuclear Lamina

Steven Graham, MD, PhDUbiquitin Carboxyhydrolase L1, Axonal Transport, and Synaptic Function: A Target for Restoring Function after Brain Injury

Spotlight Session 6: Gene Expression, Development, and Disease


moderator: Saleem Khan, PhD

Gerard Campbell, PhDControlling Organ Growth in Flies with Hippos and Badgers

Melissa Mann, PhDAssisted Reproductive Technologies, Advanced Maternal Age, and DNA Methylation Programming

Marianne Seney, PhDOpposite Molecular Signatures of Depression in Men and Women

Yaacov Barak, PhD Paradigm Lost: PPARgamma Is Indispensable for Adipocyte Survival but Not Differentiation

3:30 p.m. Exhibit Break


4:00 p.m. Plenary Session 2: Hofmann Lecture


welcome and introduction of speaker: Arthur S. Levine, MD

keynote speaker: Dina Katabi, PhDHealth Monitoring with Machine Learning and Wireless Sensors

5:15 p.m. Undergraduate Research Poster Reception


At a special reception open to all Science 2019 registrants, undergraduates from across the University will exhibit faculty-mentored posters in basic science, medicine, and engineering.

Friday18 OCTOBER

8:00 a.m. Registration


9:00 a.m. Spotlight Session 7: Mechanisms of Regeneration


moderator: Kacey Marra, PhD

Neil Hukriede, PhDSlow Regeneration, Smooth Repair, and Fast Recovery

Michael Tsang, PhDFoxm1 Is Required for Heart Regeneration in Zebrafish

Cecelia Yates, PhDMacrophages and Fibroblasts: Tissue Remodeling Game of Thrones

Charles Sfeir, DDS, PhDBeyond Growth Factors: Role of Mg in Cell Differentiation and Tissue Regeneration

Spotlight Session 8: Novel Therapeutic Strategies


moderator: Donald Taylor, PhD, MBA

Graham Hatfull, PhDFrom Petri Dish to Patient: Bacteriophage Discovery, Genomics, and Therapeutic Prospects

Leah Byrne, PhDEngineering AAV Vectors for Retinal Gene Therapy

Erik Wright, PhD, MSCan Cycling between Different Antibiotics Cure the Rise of Antibiotic Resistance?

Berthony Deslouches, MD, PhDTryptophan-Rich Peptide Antibiotics To Overcome Multidrug Resistance by Bacterial Pathogens

Spotlight Session 9: New Materials and Their Applications


moderator: David Vorp, PhD

Jennifer Laaser, PhDPushing and Pulling on Polymers: Driving Chemistry with Force

Yiming Wang, PhDNon-Precious Transition Metal Catalysis for New Synthetic Methods

Warren Ruder, PhDEncoding Material Architecture in Synthetic Gene Networks

Ipsita Banerjee, PhDAn Eye toward Islets: Bioengineering Pancreatic Islet Organoids from hPSC

10:30 a.m. Exhibit Break


Thursday 17 OCTOBER

Science2019SCHEDULE

Dina Katabi, PhD


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11:00 a.m. Plenary Session 3: Mellon Lecture


welcome and introduction of speaker: Arthur S. Levine, MD

keynote speaker: Alejandro Sánchez Alvarado, PhDPast, Present, and Possible Futures for Regeneration Research

12:30 p.m. Lunch and Last Call for Exhibits


1:00 p.m. Poster Session 2


• Basic Life Science—From Molecule to Mouse

• Translational Life Science—From Animal to Human to Community

• Physical Science and Engineering

• New Research Tools and Techniques

2:00 p.m. Spotlight Session 10: Artificial Intelligence


moderator: David Koes, PhD

Christopher Seymour, MD, MScPaging Dr. Watson: Opportunities for Artificial Intelligence-Powered Critical Care

W. Seth Childers, PhDProgramming Cells To Make Complex Decisions

Adriana Kovashka, PhDLearning To Model Visual Rhetoric with Weak Supervision

Aniket (Niki) Kittur, PhDAccelerating Knowledge and Creativity with Crowds and AI

Spotlight Session 11: Oxidative Stress


moderator: Bruce Freeman, PhD

Adam Straub, PhDMechanisms Governing Cardiovascular Redox Equilibrium

Patricia Opresko, PhDUsing a Molecular Sniper To Uncover How Oxidative Stress Shortens Telomeres

Patrick Pagano, PhD Vascular NADPH Oxidases, Double Agents of Change

Sruti Shiva, PhDMitochondrial Oxidants Modulate Cardiovascular Signaling

2:00 p.m. (cont.) Spotlight Session 12: Tumorigenesis — Speeding It Up and Putting on the Brakes


moderator: Steffi Oesterreich, PhD

Alan Wells, MD, DMScPoint-Counterpoint: Reciprocal Communication between the Disseminating Tumor Cells and the Liver Drives Dormancy and Resistance

Ferruccio Galbiati, PhDUnraveling the Role of Cellular Senescence in Cancer

Yi-Nan Gong, PhD Necroptosis and Membrane Damages in Tumor Microenvironments

Yael Nechemia-Arbely, PhDGuarding the Genome: Maintaining Epigenetically Defined Human Centromeres through Error Correction

3:30 p.m. Break


4:00 p.m. Plenary Session 4: Senior Vice Chancellor for Research Lecture


welcome and introduction of speaker: Rob A. Rutenbar, PhD

keynote speaker: Alfred Spector, PhDResearch on the Edge of the Expanding Sphere V. 2.0

Friday18 OCTOBER

Friday18 OCTOBER

Science2019SCHEDULE


Alejandro Sánchez Alvarado, PhD

Alfred Spector, PhD

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#PittScience2019 Wednesday · Human Metal Contamination: Lessons from Greening the Steel City Emily Elliott, PhD Reactive Nitrogen in Pittsburgh Streams and Fluvial Ecosystems Sarah

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