Physics, Pharmacy, and the Future Richard P. McCall, Ph.D. Professor of Physics Chair, Department of Basic Sciences St. Louis College of Pharmacy St. Louis, Missouri Reading glasses • Converging lens • Power • +1.00 D, +1.25 D, +1.50 D, +2.00 D, +2.50 D, …. • Hyperopia (farsightedness) or presbyopia • near point is farther from eye for comfortable reading • person needs to see close objects clearly • Example • near point at 40.0 cm, object at 20.0 cm • P = +2.50 D Earplugs • Difference of two intensity levels related to ratio of two intensities • NRR - used to rate effectiveness of earplugs • Typical values range from 12 to 33 dB Syringes and needles • Flow rate • Flow rate equation • Viscosity • Poiseuille’s law • Dependence on radius to the 4 th power: r 4 • Needle is rate-limiting step in IV fluid flow • Pressure difference along needle depends on • height (or depth) of fluid • pressure in vein Tablets • Scoring surface makes breaking tablet easier • Torque, elastic limit • Glynase PresTab Tablet • For Type II diabetes • Special shape allows tablet to The Eye • Acts like a converging lens to produce a real image • Most refraction occurs at the cornea • Lens – small amount of refraction needed for proper focus – accommodation • To see distant objects • ciliary muscle is relaxed, largest diameter • ligaments pull outward on lens – flatter shape • To see close objects • ciliary muscle is tense, smaller diameter • ligaments lose tension on lens – fatter shape • As a person ages • lens becomes denser and less flexible • does not relax to its fatter shape • difficulty seeing close objects (presbyopia) The Middle Ear • Eardrum, ossicles, and Eustachian tube • Ossicles – malleus (hammer) is connected to the eardrum; incus (anvil); stapes (stirrup) connected to oval window • Create much larger force on oval window – needed for wave motion in fluid of inner ear • This increased force is a result of two factors. • surface area of eardrum compared to stapes • lever system mechanical advantage ABSTRACT Teaching at a college of pharmacy, I learned early on that it was important to point out the relevance of physics to students. I spent time looking for applications specifically in a pharmacy setting, as well as applications to other courses in the curriculum, including anatomy and physiology. Now in my 18th year of teaching an IPLS course at STLCOP, the College is looking to expand our physics offerings as we begin two new B.S. degree programs this fall. We are also planning a new physics laboratory, with new experiments and equipment. As a new department chair, I am looking for two new physics faculty to develop these courses, labs, and experiments, as well as to develop more advanced elective courses appropriate for life sciences students.. THE FUTURE OF PHYSICS AT STLCOP Two new integrated BS/PharmD programs starting Fall 2014 New physics courses being developed New physics laboratory coming soon BS in Health Sciences Physics I and Physics I BS in Health Humanities Principles of Physics Need new faculty interested in developing IPLS courses PHYSICS AND PHYSIOLOGY PHYSICS IN THE PHARMACY Pre-Prof& ProfYear1 Curriculum forthe Integrated BSHS/Pharm D (129 credithours) FRESHM AN YEAR Fall Spring Biology I 4 Biology II 4 Chem istry I 4 Chem istryII 4 College W riting I 3 College W riting II 3 Pre-Calculus/Calculus/Statistics 3 Pre-Calculus/Calculus/Statistics 3 FoundationsofLearning 2 Introduction to Healthcare 2 TO TAL16 TOTAL16 SOPHOM O RE YEAR Fall Spring Anatom y 4 Physiology 4 Chem istry III 4 Chem istryIV 4 Hum anitiesI 3 HumanitiesII 3 Statistics/Sociology/Psychology 3 Sociology/Psychology 3 Literature orSocial Science 3 Literature orSocial Science 3 TO TAL17 TOTAL17 JUNIOR YEAR Fall Spring M icrobiologyorBiochemistry 4 M icrobiologyorBiochemistry 4 PhysicsI 4 PhysicsII 4 HumanitiesSelective 3 ScientificorProfessional W riting Selective 3 M icroeconom icsw /Healthcare Em phasisor Healthcare Com munication 3 M icroeconom icsw /Healthcare Em phasisor Healthcare Com munication 3 Bio/Phys/Health Sci Elective orOpen 3 or 0 Open orBio/Phys/Health Sci Elective 0 or 3 TO TAL17 or14 TOTAL14 or17 PROFESSIONALYEAR 1 Fall Spring PrinciplesofDrug Action 4 Intro to PatientCare 4 (Intro, W ellness& SelfCare, Derm ) Pharm acy Calculations (studentscan take the proficiency testup to w eek4 ofthe sem ester) Innovative Applied Pharm aceuticsI 2 (sem esterlong course) SkillsLab 1 (pre-lab lecture + 2-hrlab; coordinate w /all courses; calculations refresher) PrinciplesofMolecularBio/ Genetics(w /lab) 3 Innovative Applied Pharm aceuticsII 4 (coordinate w /skillslab asappropriate) PublicHealth Fundam entals 3 in Pharm acy AND IPPE: Clin Prev/Pop Health 1 BasicDrug Info/Intro to EBM 2 & Inform atics AND PrinciplesofImmunology 2 M edical Physiology 3 OtherElective 3 TO TAL16 TOTAL16 Pre-Prof& ProfYear1 Curriculum forthe Integrated BSHH/Pharm D (128 credithours) FRESHM AN YEAR Fall Spring BiologyI 4 Biology II 4 Chem istry I 4 Chem istryII 4 College W riting I 3 College W riting II 3 Pre-Calculus/Calculus/Statistics 3 Pre-Calculus/Calculus/Statistics 3 FoundationsofLearning 2 Introduction to Healthcare 2 TO TAL16 TO TAL16 SOPHOM ORE YEAR Fall Spring Anatom y 4 Physiology 4 Chem istry III 4 Chem istryIV 4 HumanitiesI 3 HumanitiesII 3 Statistics/Sociology/Psychology 3 Sociology/Psychology 3 Literature orSocial Science 3 Literature orSocial Science 3 TO TAL17 TOTAL17 JUNIO R YEAR Fall Spring M icrobiologyorBiochemistry 4 M icrobiologyorBiochemistry 4 PrinciplesofPhysics 4 Health Hum anitiesSelective (Option 1) 3 HumanitiesSelective 3 Scientific/Professional W riting Selective (Op 2) 3 M icroeconom icsw /Healthcare Em phasisOR Healthcare Com munication 3 M icroeconom icsw /Healthcare Em phasisOR Healthcare Com munication 3 Free elective 3 Health Hum anitiesSelective (Option 3) 3 TO TAL17 TO TAL16 PRO FESSIONALYEAR 1 Fall Spring PrinciplesofDrug Action 4 Intro to PatientCare 4 (Intro, W ellness& SelfCare, Derm ) Pharm acy Calculations (studentscan take the proficiency testup to w eek 4 ofthe sem ester) Innovative Applied Pharm aceuticsI 2 (sem esterlong course) SkillsLab 1 (pre-lab lecture + 2-hrlab; coordinate w /all courses; calculations refresher) PrinciplesofM olecularBio/Genetics(w /lab) 3 Innovative Applied Pharm aceuticsII 4 (coordinate w /skillslab asappropriate) PublicHealth Fundam entals 3 in Pharm acy AND IPPE: Clin Prev/Pop Health 1 BasicDrug Info/Intro to EBM 2 & Inform atics AND PrinciplesofImmunology 2 M edical Physiology 3 (open) TO TAL16 TO TAL13 2 2 1 1 v A v A L p r L p r Q 8 8 4 4 2 1 2 1 log 10 I I 10 2 1 10 I I Av t V Q p gh