PHOTONIC NANOSTRUCTURES WITH CONTROLLABLE AND MULTIFUNCTIONAL PROPERTIES Simion Astilean Babes-Bolyai University Faculty of Physics Molecular Spectroscopy.

PHOTONIC NANOSTRUCTURES PHOTONIC NANOSTRUCTURES WITH CONTROLLABLE AND WITH CONTROLLABLE AND

MULTIFUNCTIONAL PROPERTIESMULTIFUNCTIONAL PROPERTIES

Simion Astilean

Babes-Bolyai UniversityFaculty of Physics

Molecular Spectroscopy GroupCluj-Napoca

Current challenge of nanofabrication

To control:To control: the size, shape, composition, spatial organization and chemical (biological) function of nanostructures

Artificial nanostructures meet biomolecules

Main points of our research

Developing an experimentally inexpensive method of controlled nanofabrication:

The method is based on self-assembling process and nanosphere lithography and is able to fabricate large-area of highly ordered and shape-size-controlled nanostructures.

Fabrication of multifunctional photonic nanostructures: Periodic arrays of noble-metal nanoparticles, Periodic arrays of nanoholes in metallic films, Photonic crystals, Self-assemblies of functionalized polymer nanospheres, Etc.

Using light (photons) to extract and process information on the nanoscale:

Optical bio-chemo-sensing, Ultrasensitive spectroscopic analysis, Photonics application,Etc.

Work on progressWork on progress

SEM pictures of self-assembled monolayer of polystyrene nanospheres

Starting with self-assembly of polystyrene nanospheres

AFM and SEM pictures of self-assembled multi-layers of polystyrene nanospheres

1. Regular Arrays of Noble-Metal Nanoparticles

2. Regular Nanoscale Hole-Arrays in Noble-Metal Films

Using self-assemblies of polystyrene nanospheres as templates for nanolithography

ApplicationsApplications

Nanostructures for optical chemo-bio-sensing applications

Nanosized optical biosensors based on surface plasmons resonances (SPR)

Metal

Light Light

Plasmon

Plasmon

100 nm

Linker

BiomoleculeFG

Biomedical applications

Conventional instruments

Advantages of this approach

receptor-ligand interactions;

DNA hybridization;

enzyme-substrate interaction

protein conformation studies

label-free immunoassay;

high-throughput screening in pharmaceutical industry;

uses expensive sensor chips;

limited reuse capacity;

complex chemistry for ligand or protein immobilization

nanostructured support is cheap and easily synthesize;

can be coated with various proteins or protein-ligand complexes by charge adsorption;

monitored in any UV-vis spectrophotometre;

Surface Plasmon ResonancesSurface Plasmon Resonances

500 600 700 800

Ext

inct

ion

Wavelength [nm]

500 600 700 800

Ext

inct

ion

Wavelength [nm]

Controlling the propagation, emission and detection of light on the nanoscale

Nanostructures for photonic applications

2

( )2

( )1

f if

r

d E

Novel spectroscopic tools for ultrasensitive analysis

Novel class of optical materials

Novel light sources

Single Molecules Spectroscopic Fingerprint

Fluorescence decay control

Surface Enhanced Raman Scattering (SERS)

Surface Enhanced IR Absorption (SEIRA)

Photonic Crystals

Photonic Integrated Circuits

Telecommunication Devices

Zero-Threshold Lasers

Single - Photon Light Sources

Quantum Information Devices

SERS ResultsSERS Results

1800 1600 1400 1200 1000 800 600 400

Rhodamine 6G molecules

633 nm

514 nm

solid sampleIn

tens

ity [a

u]

Raman shift [cm-1]

400 600 800

Laser lines 633 nm514 nm

Ext

inct

ion

Wavelength [nm]

Fluorescence Decay ControlFluorescence Decay Control

10 20 30

Co

un

ts

Time [ns]

Interdisciplinary approachInterdisciplinary approach

Required techniques for fabrication, processing and characterization of nanostructures

StructuralStructural ChemicalChemical OpticalOptical OtherOtherTEM

AFM

XRD

Confocal optical microscopy

Surface chemistry*

Nanosphere synthesis

and functionalization

Bioconjugation and linkage

UV-vis spectroscopy*

Fluorescence spectroscopy and lifetime measurements

Raman spectroscopy* (microRaman, SERS)

Infrared spectroscopy*

Reactive ion etching

Metal film deposition

Modeling and

Computing techniques*

RMN

EPR

* Our laboratory facilities

We are looking for partners…

NationalNational

1. Centrul de Biologie Moleculara (Institutul de Cercetari Experimentale interdisciplinare al Univ Babes-Bolyai, Cluj-Napoca)

2. Laboratorul de Materiale Nanostructurate Avansate (INCDTIM, Cluj-Napoca)

3. Catedra de Macromolecule (Univ Tehnica Gh Asachi, Iasi)

4. Institutul National de Chimie Macromoleculara P. Poni (Iasi)

5. Centrul de Fizica Plasmei, (Facultatea de Fizica, Univ. Al I Cuza, Iasi)

InternationalInternational

1.Prof Sigrid Avrillier, Lasers Physics Laboratories, Paris University and SOPRA, France

2.Prof Gerard Bidan, Laboratoire d’Electrochimie Moleculaire et Structures des Interfaces, DRFMC, CEA, Grenoble, France.

3.Dr Anne Corval and Dr Patrice Baldeck, Laboratoire de Spectrometrie Physique, Univ Joseph Fourier Grenoble France

4.Prof Arnulf Materny, School of Engineering and Science, International University Bremen, Germany

5. Prof WL Barnes, School of Physics, University of Exeter, UK

6.Dr Gilad Haran, Single Molecule Laboratory,Weizmann Institute, Rehovot, Israel

7.Dr Victor Weiss, Optronic Center, ELOP Electrooptics Industries Ltd, Rehovot, Israel

8.Dr Peter Persephonis, University of Patras, Patras, Greece

Groups already contacted and interested in this research

Conclusions and PerspectivesConclusions and Perspectives

This project develops an experimentally This project develops an experimentally simple technique for controlling the simple technique for controlling the fabrication of nanostructures.fabrication of nanostructures.

The fabricated nanostructures have a real The fabricated nanostructures have a real potential for relevant biosensing, photonics potential for relevant biosensing, photonics and ultrasensitive spectroscopic and ultrasensitive spectroscopic applications.applications.

This method of nanofabrication could be This method of nanofabrication could be extended to semiconductors, polymer, extended to semiconductors, polymer, ceramics and magnetic materials.ceramics and magnetic materials.