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Pharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System of Medicine (Unani) DISSERTATION SUBMITTED IN PARTIAL FULFILMENT OF REQUIREMENTS FOR THE DEGREE OF MASTER OF PHILOSOPHY IN BOTANY TO THE ALIGARH MUSLIM UNIVERSITY ALIGARH-20200I s AUGUST I98I RASHEED UDDIN AHMAD
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Page 1: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

Pharmacognostical and Botanical Identification of Some Important

Bark Drugs Used in Indian System of Medicine (Unani)

DISSERTATION SUBMITTED IN PARTIAL FULFILMENT OF

REQUIREMENTS FOR THE DEGREE OF MASTER OF

PHILOSOPHY IN BOTANY TO THE

ALIGARH MUSLIM UNIVERSITY

ALIGARH-20200I

s AUGUST I98I

RASHEED UDDIN AHMAD

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Ds 2,/ 7

2 4 HAY !S83

^

<% CHE> m^

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OP sane C4PGRTANT svRK vmx^ usBD m Tt^mi SYSTEM a? tmDicma immt)

Dlssarxation submitted In partial falf Ument of tiio requlroratitts for tha deqreo of r*3ster of Philosophy In aotany to the /dlg^rh ;'Sisliw University, nllg-Jrh - 202001.

ri^HliiiD UK'tr-i rt!I4iP

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tha illssartatlon entitled "FtidTaacognostleal and jSotanioal idtntlf leatlcin nf toad iapi»rtaiit Bark Qmqn used In Indian SyitaiKi of M^dieina « Unani* syhiitted by Raaheed Uddtn Atnad is eonaidtsed suitayie §»s i3t» avord of M.Phil da^soa in aatany

Header, oapartiaant of Botany

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A C K n Q i h E Q G E M S t| T

I take th is opportunity to axpress tay sincere gratitude and thanks to Dr. A.K. % Ghousa, Reader, Oapartn»nt of Botany, Allgarh ?*jsllai University. Aligarh and Dr. M.S, /m^arl, Senior Scientific Officer and Ofllcer-ln-Charge, Pharraccopaelal Laboratory for Indian fJlsdlclnes (P*I.•I•^U}, Ghaslabad for suggesting me this problem and for the i r constant supervision and guidance. I also thank Dr, J»3, qadry. Principal, Handard Co l l e^ of Phdraacy, New Deihl-4i0062 for helping FUG from time to tlrae In th i s regard.

fAy thanks are also due to Hakln B*H, naziiack. Deputy Adviser (Unanl), Department of Htealth, ?Enlstry of Ileaith and Family vielfareg !«ew DelhWllOOll for extending cooperation and helo during ths course of th i s «ork. Tf^nks are also duo to Valdya Bhagwan Uash, Daputy Adviser (Ayurveda), Deptt. of Health, rUnlstry of !»)alth and Pan ly .#lfa2M, Mev; Delhl-l iooil ^nd to njy coileoguo MaUlr S.I . Yusuf, iiesearch Officer (Unanl), Depart-nj^t of H^slth, Ministry of Hoalth and Family .fclfare, mn Delhl-XlOOll fn:* thmr holp on 'irltinq the Ayurvadlc and Dlianl aspects of the drugs respectively. Lastly I tfienk my wife Dr. Zeenat Basheed, who has been a constant source of encoui*a<|oinent throughout the ^Tinting of t h i s >r«>rk specially by glvlna constructive suggestions on the cheialcal aspect ox the t f e s l s .

Dopaartsant of Haalth, BASHaED UDDIN hB¥iD Ministry of Haalth ^ PsEilly i^ifare. New Dalhl-llOOil.

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C O H Y E N T S

I, Ijitroduction i_Ai

2» n«vl0v^ of Litsrature 4_2 8

(A) Historical A_2i

1) Chinese School of ^^dldne S U.) Inalen School of 'tedicina {Ayurveda) e

l i t ) ct^yptlan School of ;vtedlcine 8 Iv; ac«ei5 - «^^^»«*of ?*>dlcine ^ v) arab School of ?^dictns i 5

vl) Qraeo wv-ab. System of rtedlclne (Unanl) 2 0

(B) IiwoilQtt of Umnl Systam 2i (G) Indian ic l sn t l f l c Cksntributlon 2 2

3 . Pifean of '.itork 29

4 • Met hod olo gy 3 0

6, appDndlces

(A) List of Single Drugs used in Unanl System ' -^ ' (Bi List of InportiJnt n .-k 'rug;3 u^od in -.S,. «., I-III (C) List of aark Drugs to bo vwrKed out I {O) -10 fa ranee l i s t of t\w v/ork done on B irk Dtugs 1-H

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U ) INTRODUCTIGN

There are about X50O*20CX) plant species In the l l toratux*

of drugs report^^d to be madlcti^l In our counrtry* They axB

attr ibuted vdth a nuiidaer of mdioit^l vlirtues, uses, properties

and also r^spmber&d i4th a nuaisjr of different vernacular naoes

In Unani» Ayurveda and Siddha Systems of :adicina. At present

sod© l&X) dnig yielding plants are ^ 1 1 Idontlfii d d>r^ well known

wdth their useo «nd vernacular names. S t i l l there are raany

important druq yielding plants com^nly used in our Indian Systems

of r^dlcine yot to be identifl&d and studied for tlieXr medicinal

values* Therefore, thore i s a meed to take up th is aroblera on a

large scale for their ojcact identification, oxporissJrital cult ivation

anti scientif ic !.?v&j.uatlon by ujoans of iiotanical, phamacognostical,

cbiniical, :ih WK*/.'CO logical and clinical scroening e t c . , to lay down

the standards for single drugs and also th» comtjound formulations

so t tBt a st-»ndard phv^rnracopoela could be produced In order to

brif^ the parity in ths compoundl forinulations, end to produce

standard druos throughout the country at par with Mlopathic

Syaten. •

our country at present is not self sufficient in pharmaceu­

t i c a l productions. Keeping in vlevy ths exp^^idlncj netds of the

pharnia«:eutical Industries and their increasing den^nis for a

maxiajum output for raoetlng the iwblic dein£'nds, ^lt^lost attention

should be paid to the production of raw taatPriaj. (in thi? form of

crude drugs) by way of ejjperlnental oultivatlon through various

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* * • * 5 » * *

survwy uni t s , rasearch centres md other Inst i tut ion^ xtiining

under th© auspices ef i taty and c©n«irdi Oovtimaents in the country.

In Itoani, Ayurveda andl Siddha Systaas the dztigs ar© us«d In crude

fcrias only i . c , vtlthoyt scl-^nxi^lc »3f/3luetiori« Mn tliesa drugs

wtli !» oviluMt'^u on thQ l ines , raentionad above, ther» the i«al

rc la of tliOGS drugs cen be undorsto^J in coiabriting different

di£ieasQ3 at par virih ^ lopa th ic System*

Basically ihQ drugs of Indian Systesis of sitdiGine C^ani^

Ayurveda ar.c' liUdiha) Jte used ei ther singly or in coidbinations

of the variaui* foarol-tlons. A nuabsr of plants ajoj tacdictnally

in our syac^Jiss have chPraically toon aiwlysad as ovld&nt fijoa the

publisl^d ^ork in the country as wi&ll as ateuad. fe slipuld m)w

t r y them pH^rnianoloqically end c l in ical ly to prove t*r efficacy

of t t » exact, affective and active e^^mleai comtituents* the

ph3rn»colo.3icul testing of th£? coapotind cruci© uicuq^ (used in

various for^milations) can pot hB don*- unless aach and every

single drug yielding plant i s Ictentlfl^d bo tain lea l l y , phamacog-

no3tlC3lly atd chsraicatly and t l^n pirt for phsrn^icologlcal and

c l in ica l t r i a l s ,

India is full iiith important oediclnal f lora, especially

th5 Hiraalayan ranrjes extending froa South Bast to florth itest,

the Gangetic plains and the Wesitern Gihats ertenr^ino frotn North

to South, providing liaraense scoiae for ^search vorkers to explore

the f i e ld . This ii^alth is in surplus and ctm easi ly he u t i l i sed

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- 3 -

to fead out thp drug Industry as far as t l ^ cruda source Is

concernedt Uioar mcU a yld* rar^o of cllradtic conditions of our

couritry, i t Is naturul to vwa a vdcte range of ns^dlclnal plants ,

even tho iUanti of troplca.l mH s»»^>-tropic£ J, c' i.plnc: <3nd sub-

nlplns rc.-5lo-;a ..re x t '.^th In ons part or the other. I t Is

f'ifficiiXt tn flu'i 3ny other c-unt^y of cij i l l jr tj'pe, v/hsr© such

a varioty ox .ii'dl^ln-^i plants grov viil'U :^early 50 per cent of

plants used In tte i^rltish Pharraacopooia are reportc J tc grow In

our cointry, l>v>uqh '.^th variation In the spaclei^. *1o3t of those

plants grovln;j Hid In our country ar^ enivjally c d l i c t e d for the

p» armt«c*3utlt Rl Indiujtry. .. vary Itolt-^d ymmtor rf dTugg used in

our systems la Iraported.

In v*Gv; of thQ above niantlon^tj d l f f lcul t las Coverninsrtt of

India In th^ '^inistvy of Health and Family »lalfaro (Dt'partment of

•-iaalth) hJr?. oita'ljllfjhJd c Cell vdth tliP mm2 liiu.lt n Systems of

'fedlclne (i!»3.'4,) no\< Tr^c It tonal Sy^tini^ ox piiiclne (V«3.:.U) to

carry out thj rosearch ^msk on tha drugs J-VJO In t ' ^ s e aysterag and

pCQpsxn 3 W.-rtlonal Pharmicopoalg :*o:: e l l 'zh*i t\\xoa Systems

raspectlvaly under the i3rugs and Gosnetlcs a c t , J.940, To speed

up the P-Qs-inrch '.^jrk on those drugs the f^lntstry has established

a Drug Standardization ^nd Tasting Laboratory/ with th© naiae P.L.I«M,,

(Phsrreco'xjolal ?*aboratory for Indian *dlcines) a t (Siazlabad.

/vlong d t h th is the "ainlstry of Health has «Iso estahJ-lshed

separata councils for lJh«inl,Ayur«/eda and Siddha »ysteina at Nfew Delhi

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a* 4 *•

as Headquarters. These councils protaote the viork by sanctioning

various projects and sehen^s to carry out the research work on

a l l the aspects of the drugs used in tn^i^n Systetas of ?A»diciii@.

(2) RBViaw a? LCTERAtlBE

(A) HI3TCRICAL

To understand exactly the usage of drugs of plant origin

(basically) and other originst es to how they canit into prominanee

in medicine through out the vvorld, i t is necessary to go through

the developmental history of these drugs* This vdll help not

only to the students, research scholars, and the imrkers engaged

in t h i s field but also to tho physicians and t l ^ manufacturers of

the drugs of Indian System of J^dicine especially the Unani System

in th is country, yBscause at present our Systems of Medicine

(iMani, Ayurveda and Siddha) have a number of drugs in coixnon,

though they are of different origin, source and belong to different

schools of medicines. These drugs even now are identified with

different vernacular and comsion names though the botanical identi ty

i s one and the same. Similar is the case vidth animal and mineral

drugs, due to which identification of the actual drug becomes

diff icul t and leads to adulteration and substitution and l a s t ly

to the 8ul>>standard cy wrong preparation of the drugs in these

systems.

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- 5 -

The history of the drug usaqo goes back to the pro-

his tor ic ora. Basically thsro are three schools of raedldn^ in

th9 v40zXd vfhieh can be assigned to u t i l i s e the drugs of plantSt

animal anri lalneral origki for curing differsitt typos of ailraents

In different ways, with a difference of few hundred years of

developisent of t h i s knowledge, siimiltaneously. These am Chinese

SCIK>QI of Medicine (2,735 B.C.) in th i Bast, Indian ?4»dicine

(4,500 - 1,600 and 2,900 - 600 B.C.) and the Greek ?tedicln»

(460 B.C.) in the .fest respectively,

( i ) CHINESE SCHOOL OF f BDICINa

Origin of the Chinese medicine Is at tr ibuted to the mythical

god believed to have flourished about 2,739 B.C. The Chinese

madlcine t^s a Fhanaacopoeia l ike con^llation in Chinese called

•Pun Tsao* or the 'Great Herbal • , having 40 volurass describing

several thousand preparations. Chinese ^ r e the ear l ies t to

en^loy goose grease the *adeps aiabsrlnus* of tlw la te r phanpcopoelas

as a preferable fat for Inunction, and thP modem scient i f ic

researches on the peneteratlng properties of fat places I t on top.

The other nedlclnes employed by the Chinese from various origin

(plant , anitaal and mineral) are described bslowi-py\NT ORIGIN I

1. Sea yfeed as Iodine Source

2 . Rhubarb

3. /M:onites

4 . Cannabis

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«• Q • •

S« Sphidira (Sph^drins soiirc©)

6. Caiaphor

i . Iron

2. Swiphur

3* ?Aircury

4 . Aluia

i^B^aL OaiGIMl

2. Toad's Sye-llds

3# Sarthworms

(II) iNDBN scHoa OF mmcim (AVUFtVEm)

The vedas ar© the earliest sacrad boolss of Hindu isytholo^y,

Thoy ar© feur In maiibar vl8#, Rlgveda, Saiavada, Vajurvada and

Atharvaveda» Hindus believed that they W&TQ th© words of God

and never coaiposed by raan* I t was swpps^ed that they v«re ta^^ht

by the Qetd to the sagas (revealed v^ were the seers of t ru th) .

There was really no veda called Ayurveda, Its exlstance Is a

rayth. According to Susruta I t Is an upanga of Atharvaveda, I t

was raised to the Status of a veda dnd appended to the Atharvaveda

to give the science of nedlcln© the necessary sanctity m^

authority* Ayurveda is the najae, v^lch th© ancient iJfKllan gave

to thslr science of medicine (Ayur-iauans l i fe and Veda to know

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wm f tm

or a t t a i n ) . There are t»*o versions of I t s or ig in . The raedlcal

school traces I t s origin to Bhardwaja, «ho received I t from the

God Indra* The surgical school traces i t s origin to Dhamrantari,

viho received I t also froa th i s Sod. According to Charaka,

Ayurveda eraenatod from the creator •Brahma* who revealed I t In

I t s en t l r l ty to Prajapathl, *l«ord of the c rea tures ' . From him

i t v/as passed on to the As^ns , the divine t-vin horsenen, the

helpers and the healers among vedlc gods. They passed I t on to

Xndra, king of the god, and from him mankind received I t s divine

wisdom. Other sources believed I t to be derived from Rigveda

compiled beti^een 4,SO0ui,6oo B.C. and Ayurveda 2,500 B.C. Charaka

and Susruta are considered highest authori t ies . Charaka gives

50 groups of ten herbs each, till© Susruta has ar ran^d ?60

herbs In 37 s e t s .

In Ayurveda, beside the classical works of Charaka and

Susruta, there are many i i^»rtant works called 'Nlganthu* on

Ayurvedic !A3terl»>l^dlca« The oldest ffeterla-Medlca •Nlganthu*

appears to be tha t of Oeodas Kashiraj of Banaras (a king} who is

also believed to be the Incarnation of lord Dhanvantarl. H& Is

believed to have taught his •Dhanvantarl Sangatha» to his d isc iples ,

av^oo9^hem Susruta was the most renowned. I* Is believed to have

written anothsr book "Raj Nlganthu* on drugs but some believe

i t to be written by another Valdya nac^d Dhanvantarl, wtK) lived

during ik& tlma of king Vlkramadltya* There are about 400 drugs

(herbs) described In th i s book, v^leh has been glvjjng Inspiration

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«• s **

to raany authors l«iter as the raaln source.

Sarangdhar is believed to hMm lived in 8th Century A.o*,

has licrltten a book on materla-rafBdlca namd aft»r him* Bteva?aisra,

vAm Is ballevad to have liva<lln i4th Century A«D. was a learned

valdya of his tlias and was a nsitlv® of B^iaras (now Varanasi) has

written a comprehansiv© treatise on .-^dlclne named 'Bhavaprakash*

of i-tfhlch •Bhavaprakash Niganthu* forms a part^ descrlbii^ more

than 600 <teigs Including some druga of otter systetas. Narhsrl is

quoted in Hngllsh books on Ayurvedic drugs as native of Singhaiaar,

Kashmir, He is described to be the author of •Chauramanl* or

•Raj Nighfflithu*. ThQ nasie of Lala Salig Bam i^ also wr th

mentioning «*io was a netiva of 'toraKlabad# JP is the author of

•Saligraa Nlganthu* which describes 1574 drugs andi illustrates

some drawings giving their synonyms in other languages*

( i l l ) BO PTmN 3CH0GL OP I DUSII©

In the Itost, bsfore the advent of (Sreek t^dicinSg records

of drugs usage are also availalble In the forra of Egyptian ^iteterla-

ftedica, Assyrian and Babilonian J^aitaacy# The faiious "abers

Papyrus" believed to be ^trltten about 1,900 B.C», contair^ a

collection of prescriptlom aivi foreiul^ with a wide range of uses.

The followjing drugs of plant, lainerals and anliaal origin are

described In t t e Egyptian rteterla « Rfedica (Ebers Papyrus).

They aret-

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« 9 -

SLAKT (B£G£Nt

1 . Oil (of plant soured)

2 . ^ n e (of plant sourco)

3 . Bear (of plant source)

4* ^ a s t -•>do-»

5. Vlnogar -do-

6« Turps ntine

8» Castor o i l

9, '.iyrrh

IQ. 'tastich

1.1 • Franklncc-nse (of olant soiarc©)

IP. ./orm Wood

J. 3 . Hloaa

.14. ')'i5.u'"l

13 • Cumin

16» Pi3ppor:dnt

17, /-mi 33

19. Fonnoi

IC. Saffron

20. Lotuu flovgora

21. Llnusjed

22. Jonlp^^r berrlao

23. lisntenQ

24. ?oppf

25. 'Sandra gora

26. Gentian

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• 10 ••

27» CoXchicum

28* Squill

29. Cedar

30* Elder a0rrles

31 • Honey

32. Grapes

33. Onion

34. Garlic

35. Acacla

36. Date Blossoins

1 • Iron

2 . Load

3 . ^Itwn^n

4 . 'lagnesla

5 . Nltro

6. VeroUlon

7 . Copper Sulphate

8 . ithlte Lead

9. Crude Sodlura Carbonate

10. Salt

11. Precious Stone (in finely powdered «Calcln0d» forms)

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- 1 1 *

fiitifimL cBzm.ni

I*

2.

3 .

4,

6.

7.

8,

hizzardH Blood

Swine's Teeth

Putrid %at

Stinking Fat

?itolstur0 from Pig's Ears

AUk

Goose Grease

Afs's Itoofs

9. Anlcjal Fats (from various sourcoa)

10, Excreta of various animals (including BJman beings, i)onkay'6, Antelopes, Uoqs and Cats and oven F i l e s ) .

In the l ibrary of St^rdana-Polus a t ^ishurbanipal (650 B»C.)

clay table ts have been found belonglijg to Assyrlens and

Babylonians, relating to aodlcal and pharcstxeuticfd subjects.

The IT l i s t of drugs resembles that of HgyiJtian 'laterla ^Aadlca,

whore 2S0 herbs, and 120 mlnaraXs and stcsnas ©re described,

among which are Cassia, Cinnamon, Costus, Qj'rls Root, Anise,

jasmine. Oleander, Allanander, Cathartica, fttnt, Ifenbane,

Liquorice, Alcohol, Terpentine and Bser of Plant origin while 6f

anlaal and mineral origin ars F^ts, a l l s , .fex, Bltucien and

hixM e t c .

(Iv) GREEK SCHOOL CF fJlSDlXJlNUt

The Greek medicines' origin Is traced back to A-esculaplus

v4» was probably a historical personage ar^ subsequently cteif".ed

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by the Egyptian and other ancient people. Actually In the vfest

the history of medicine and phiraacy berjins from Hippocrates,

v^o bom In the Iseland of Cos In 460 B#C« and Is considered to

be the father of oysdlclne and said to bo a dessendent of

Aesculapius, fii his viorltlng Hippocrates has laantloned nearly

40O slTsples as isBdlcinal substatnces* Theophrastus (370»287 B.C.),

l a t e r on who received the herb garden of rtrlatotle, rnontloned In

•on the History of Plants* and In another book "on the Causes

of Plants'* 500 drugs. HOa«ver„ t t e most autl^rltatlv© and

significant Pharrnocopoelal t roat lse of the Greeks was the text

of Oloscorldos (60A*D»)* Met i s said to becoiae Surgeon In Meuro*s

anay to leam the flora and fauna of different countries. During

his anay career, ho tra^relled I taly, GraQce, Hsia ?4lnor, Spain

and France, where he collected a vast number of drug samples of

plant, anliaal and mineral origin and confiiwsd ths l r Identity

and mineral virtues v/he raver he got the oppoitunlty. His famous

t rea t i se on laaterla-medlca was f i r s t published In Venice (Greece)

In 1499 and for 160U years I t served as -Pharmacological Vadtnecuia

In the history of raodlclne* This book vias translated Into arable

and other European languages and is very often quoxed In the

works of Arab authors. This t rea t i se «»as arranged In alphabetical

order and described the drugs of different origin (plant, animal

and ndnoral). Those aret

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- 13 -

PLANT ORIQINl

1.

3 .

4 .

S.

6.

7.

8*

9.

10,

i i«

12.

13.

14.

15.

16.

17.

18,

19.

20.

21.

22.

23.

HCacia

Aconlta

rtloos

^ t lse

SalGara

Bitter Almond

Buck Thorn (Rhanmus)

Cardaigoia

Cutnln

Dill

Hlatarlum (Jtilce of t t e Cuciaaijer f ru i t )

Gantlan

I^mlock

Juniper

Lattuce Vinegar (Vinegar of Lactuca)

Llchsns

Llcorlc© (Liquorice)

,/iandrak6 (:4andragorQ)

Mint ('4Bntha)

penny Ho^l (Penny wwrfc)

poppy

Rosa Cdl

ti/ona Jood

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2* Arsenic

3. Bitumen

4* 31rd Lln»

5 . Bcin9 (Salt)

6. Calaraifia

7 . Caustic Lyo

8* Soct

9* Vordtglrls (basic Coppar acet^t©)

iO. ftilte Lead

XI. A nwisBi: of mstsllc oxides. Sulphates and Sulphides.

mtm. mtm,n; 1. Ash of Hlp^caiBpus

2 . Cjnthrldos

3. Fish glus

4. Uirino

ariiiipsi

X. Boiled Oil

2 . Starch

3 . iiin9

Aiaongst other Oreak vwrksrs the w^imB of Pliny the eldar

(23-79 A.D.) and Galfen (130 A.D.) are w r t h nisntlonlnq» Pliny a

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contemporary of Dloscorldtes on '•Natural Histoary* wrote 37 boo)«»

out of vMch 20-27 deal with medical botany (oiedicinea derived

from plants}t 2S*33 deal vdth BMt&ri»i«edicd i . e . othnr than

botany (drugs dterlved from ths bodies of wsn and other land

aniiaals )* Similarly Oslen, who is believed to have died in

Sicily and born at i rgan&na, has kept a pharmacy for a long time

and is bcli3vad to h3ve dovelopsd a nuaibsr of msdicinal

preparations of plant origin called "Galenicals*. On Pharmacology

Galen Is credited vdth 30 books. In om of the books (translated

Ittto Latin under the t i t le "De Clmpliclbus*, Items have been

arranged in alphabetical orders and enjoyed great repute* His

other works arsre translated Into nrablc. He also became the

Physician to Comodkts and during his trcivel devoted a great deal

of his time in collecting the choisest drugs to have at his

disposal. In his writings he alvays empnasised on the importance

of tlie pure drugs and careful liendling of them and advised to

the r&adBi:s *in order to know the druijSf inspect them not once

or twice but frec^antly, for tliough twins look alike to strangers,

they arc e33lly distinguished by frionda".

(v) H:mB SCHOCL OF FAdDiClHst

/tfter the dteclina of oBdiclne in 'ionQ a?id the texts of

earlier Greek wrkers ware foresaken, Galen gradually assumed

highest authority in modleijie and luckily tha oroek medic ir^ found

its votarias in Arabs, who trcinslated as naioh .Ajrk into Arabic

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X6 *•

as they could found* Great contributions have been niade by

ths Arab physicians on the ajadiclnal proporties of the plants»

though thei r publications are based on the oaterla-iaBdlca of

Dioscorides and Gslen etc*, but '.vith lo ts of vPvi additions

alongi^th the foot notes and coiaraontarlos. There Is an abundance

of references of the book •^^Imallki* of Ali-ibn-Abbas, and for

the develoofuont of t l ^ Arab loadlclr^ as a wihole, the naiaes and

the contribution of luiain^rlos l ike Qusta-bln-Lauqa^ Hajjaj-bin-

*%tar, Ibn-ui-Batriq, Isa-bln-Vahya, Ahn3ad«bln«abi-al-*Ashat,

Ibn»l-Jaljal (GcslgiJl), Abu :iahai .'JU^ihi, / •li-lai-Saadiq, Abul

Hasan aarshl , All-bln-!>lzvian, Ibr*»Wiiafid, Maki:*! E.na5luddln Abul

Mansoor Sald-bin-Bushar-bln-^^bdus, Jcrjl-^idnn, Abdul Q^slm

Halaf lbn-3l«^bba3 al«.2ahra4Ji, VUhann^bln-'i*ini' *\'ayh (777«857 A.D.)

Abul h^oan al-Tal^rl (9th contur/) , Yaqub bln-I^haq al-Klndl

(8vXJ*«87 A,D.), Abu Bakr 'Aoh:itnnaci bin«-Zakorir Tazl "fahazes*

(854*93a M.D.), Shaikh Bu All Sarins »Avicen ie» (98(V1037 A.D#)f

Abdullah .'Aohaiaioad Al«Xdrlsi "cher l f (1100-1166 A.D.) , Zlauddln

Hbu :%3hacEiad Abdullah Ibn-^-Ahaad ol.-r^allkl *»Ibn«al-!^ltar"

(Il97-4.a48 A*D.) and Iba an nafla (1210-128B A.D.) are worth

mentioning*

Bastdos al l the physicians and workers already ni^ntion^d

In the preceding paras one should not ignore the nas^s of workers

who wrote valuable t reat ise on laarfceri^^aedlca l ike Yahya-bln-Jazla

*fAiqhnl«», Abu T:ehan al-Berruni, Itojl <lain IKldin Attar , Shaikh

YUsuf of Bagdad.

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Jakarta Hazi 'Rhazes* Is ciredltod wdth having written

230 works, Soiao of v^lch are on Jharnpceutlcal a s p ^ t s * Rhazes

aniongst his c^ntomporarles was krmm as Galen of his tltns* His

most fammis contribution Is "Al-Hawl-Kablr* or "Continents of

Rhazes**, Qarlson In his history of inedlelne* classes Phazes

with Hlj^^crates In his Infltionce tipon laocllGinQ*

Avlconna aaongst th© Unanl I^yslclans was krmm siiaply

as Shaikh* Hi Is the ^ r l d rerajwr^d author of th0 book Canon

(Al-qanun) • In fact , he was th© foumter of G i e e o ^ r a b School

of 'tedlclne. During the talddls ages ^te Canon of Avlconna was

by far ths laost popular toxt book of cisdlclns In Huropo and was

roost frequently quoted by la te r writers , Ac^a l ly Avlcenna's

work Wds> considered atithoxitatlve and used by the Universities

of Europe t l U as la te as 1650* I t Is his likeness that adorns

the dlploisa of Phanaaceutical Society of Great Britain. His

second volisae of Cai^n described 119 drugs.

Al-Idr ls l was bom in Sevta and educated in Spain. Ha

i s famous for ths collection of herbs. Alongwlth him the n&tm

of Hahseed-uddin-Surlg who toured th© l i i l l s and forests of his

country Syria, is associated in search of asdiclnal plants*

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Ths rsforenc© of his wrork Is found In the famous book •Al-Aqaqlr*

Ca^llevod to bo to'ltton by |}»vdX«»B^itar} (vhere 1400 drugs are

doscrlbsd^ and referancos of ciora than iSO Arab and Syrian

Physicians Who vrnte concerned u4th the collection of the

information about these drugs are laentioned* Out of th^se 190

Physicians, the name of Al-Idrls i has been referred as 'Sharif»

more than 200 tirass and is ballovad to be un authority of drugs

of plant and aniiKil origin of llorth /ifrica,

Ibn-al-Biditar vi/as chief bo1;onlst in court of Egypt. Ffe

travelled tlirough North rvfrlca, Spain, Grp^c^j I ta ly , Syria and

Hsia .linor. l-Ia visited the botanist of ©v^ry country and the

herbs in the i r natural gro\tth and investl'iated the i r properties

experiniBntally. In his monuntental imtk "Jaae-ul-^fredat* collected the renerks of Dloscarldes, Galen, iiazes, Avlcenna and

others on drugs* Tt deals with 2,C30O drugs out of vihlch 1,700

are of plant origin alone* Another book wjritten by him on materia-

Ejedlca Is known as fKltab»ul-.^lugtol fl-^lwidi^iya-al-lifarreda*.

* according to l^oclerc the naTiss 'Sharif* refers t o Abdullah f*)haraaad Al - Idr l s l . Previously, the exact period in which he wrote the cptarla-aedica wis not knoi^ • I t Is only recently that Prof. Halmut Ritter has announced the presence of the book "Hi rtqaqlr" v#hlle ht» -.-laa scjarchlng thf? nianuscrlpts on th i s topic In iiosqubs and l lberarlea of ConstantInopla^ as l ike the los t book Of Hl - Idr l s l . Later on OT* Max layerhof has published his papcir vi'Siere he has confirmtJd that th is oook Is the samp by rtl«Idrl8l which was deemed l o s t . The manuscript of Al-Agaqlr Is kept In tha l ibrary of History of lidlclne, Istanbul, on v#hlch no data Is vtorltten. Ptevlously I t was believed that »Al Hqaqlr* y as written by Ibn-^l-Baitar,

«« ^ Egyptian edition of the book Is avail^^bft* Part of the work KiQ^ publlsh^^d a t various times In L'- tln under the nam© of •Slrapllca*. A French translation by Leclerc I'-i also available as •Notices e t ant raI ts des nPnuscripts do la Blbllotheque Natlona^le*.

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m X9 •»

Shaikh Da«ood of Antakla vopote a book {ahoat 1CX53 A,H»)

on medicine nara©*! »Tadhklrat-ul-^bafe ( (^MF^J/^) batter

knovKn as 'Tadhklra Dawood AnataHl ( (P^/yh ^Z ) describes

several hundred harbs besides anliaal ai^ mineral origin drugs.

Abul Farj-tbn-al-Qaf (63CV.685 A,H,), the pupU of Hakim

Ibn"l-Abl«4J8alblya (tip famous author of *Tabqat-ul-iAtlW>8 • and

v«a8 given the t i t le of »Aa»etv^-Daula» In the royal fort of

physician). Is the autiK r of several books on medicine besides

a coianentary on Canon (Al-Qanum) of Avlcenna In six volumes.

His book •Kltab-.ul-Urada«flf.al«Jlrahat« contains 20 sections, of

v^lch section 11 gives the description of 212 drugs dealing vdth

surgical practices and! section 20 d^als with Salves, Ointments,

and Oils, used for dressing \«Dunci *

Viisuf-bln-Omar Saheb*ul-VS9iaen (died 694 A«H.) the author

of 'Almotamad* printed in Egypt, has described only frequently

used drugs with tlielr actions.

Arab's contribution may also be recocplsed by going

through the records on the translation work done on litdlan and

Persian books Into Arabic, Tills aspect of study highllc^ts the fatf

that hovu the drugs of different origins (Greek, l^rsian, Indian etc

got mixed up, and were included in their medicaments and the

raatsrla-medlcf thiough ages. VUhanna-bln»*tesawayh In his book

*Jaiie-ul*Tlbb* wrote that a number of books of Sanskrit were

translated into Arabic* The authors whose work was translated are

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KlfilEitr, ManJaJiy Bakhar Sal©h-blii»la>iUia ®tc« th© lfip^i;afit

books transiated are •Isray-ul-ltewalld*, *Kltal>»tjl«Adv«a»» Kitab

Shark-ul-ittiidl*, Kltab»ul«-Soim«9, Kitab Sasini-fWribb-AsBia Aqaqlr-al.

Hind*, »Astankar-.iil»Jara&», «fiikhtasarw4il«Hlnd-fl-al-Aqaqlr,»

•HaJarUiil-Atlbba al-Hlnd al-Tatrtan fl«»al-Aisrai.ml«Alal| 'Ra© a l -

Hind fl-.aUmyat-o*Sansji^» and Shanaq Hindi e tc .

The sv®'*®^ «*ileh originated In Qse^m and davalopod by

hmtm Into an ©laborata iiiadlcal selenee on the basis of thi

teaching of Hippocrates^ Dloscorldtea and Oalen, is called Grefto'-

Arabic System of Bfedlcli^, i^lch later on» after centuries, e a»

down to India «tlth ^slltB*s advent ssnA flourished «dth tht i^ae

Unanl System cf Fledlclne. I t has Imbibed the best vifhst vm% knmm

to other conteaporajpy systeias of Biidlelnes In BwPt, 3yrla» traq^

P^sla , l^dla, China and otter Middle and Far Eastern Countries,

as already taentlmied*

AsKmgst the m^im Hiyslclai^ the naiaes of Hakim Syed

Mohffii ad Hiisaln, Hakljs Ba^a All t^an of Osccant Hakln ^hasRsad

Azam IQian, Hakiia Bloh^siad Najiaul Ohanl Khm are very Important

to be laantloned* Sltallarly Hakla All <lllanl, Haklis Ktoaln and

loid last ly the naoie of Haklia Shareef Khan may also be liKsluded as

lo^r tan t contrlbtiters* Hakim Syed Ij^iraiad llisaln Mho vnrote

•ltekh»an-ul-^dvlya» Is the pioneer wor^r among the IManl Tablbs

(Physicians) In &)dla* His original work Ift in ^ r s l an language

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which has boon transiatad toto rdu also* It dascrlbas yearly

1»9C30 drugs including hundrods of harbs growing in Xndla* It

also descrlbas Cinchona hark and Quinlno* Hakiia Raza All Khan

of Dace an is the author of *Tadhkirat*uI*Hlnd«, in Parsian

language, on Ihdian he j^ . Ha mentlonad the Sanskrit m¥i South

Indian naiaas of soma herbs cm the basis of his ontn oxperlenee and

o'3servation* Haklia Mohaniaad Asara Itian (dlad In 1902) i s the

autlK>r of "t^ aasterptece "fAjheet-l- zara* in four volu!i9s,

describing several thous£)nd drugs Including soiae used in

Allopathic laedicine* Maklni Mohaci!!iad Hajmil Qliani i an (son of

Hakim Azam Khan*s sister) nrota a voluminous book **Khazanat ul-

Adviya* in 1915. It is on the line of '• fluheat-i-AzaiB* and is In

Urdut induces more Allopathic cssdiclne, describing 2,612 drugs.

(B) Vf<BJSB OP XJ^^X S^E|^;

After giving the overall picture of the history of the

usage of drugs i t is inQsortant to laentlon S€ 9 aspects of

philosophical and theoretical ideas <m v4ilch the treatiBPnt of

QreooW^rabic or Uhani System of Medicine, in our country at

present, is basod. In Uiani Systems of Jtediclne different

theories viz, of Temperament (ittzaj), HiKKJurs (Akhlat), Psychology

(Um-ul-Mafsiflt) and lastly th» Vital Sipirt or Soul (Puh) play

very important role in the treatment of different types of

ailments. It is mil established tl^t only tt^se theories have

led to the evolution of thP present day medical sciences. Amongst

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•• 22 .*

thme^ the theory of »T9©pe3pai!i»iit» and the theory of *fteotirs«

occupy very liaportsnt placo In ciassllying i,\m Individuals

(patients) and the drugs, thslr usagi for varimis aili^nts In

relation to treatsiBnt, diagnosis, and syaptaaatology «tc# In

•^Id systeiB ttier© 3s a general concept of variation In the

tempeiaraant of Individuals (gaiptlc mafcs up) md that Is v*iy the

l4idlvl(&ials and th® drugs are classified Into hot (har), cold

(baarld), aolst (ratab) and dry (yaaMs) types* (kt tho basis of

these theories the us© of these dinigs cans into exlstance by way

of experienceg obsexvatlons and practice, which later on sloway

and gradually caise do m t» the { resent gsf^ratlont

In Iftianl system of midlclne, the drugs used for various

alli!iait are obtained froia plants (i3»stly)« animal and ndneral

smjTces* There Is a general belief In -ttiSs system t l ^ t ths drugs,

soiae how or the otl^rt ^ ^ properties and action to cure the

ailments without side effects* I t Is true also as no toxic effects

so far have been found In the treatiaent of this system but without

scientific e)Q>lanatlon» Similar Is the case vii^ other Indian

systsias of raedlclno* As these drugs are used In their own natural

fornix and used imsynthesleed makes ilm basic distinction bstween

the Allopathic and these systsias* Because of l^ls fact only,

tl^se drugs got the nan» •Cruds drills' am are med either as

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•• 23 ••

s*iole plant (plant origin drugs) or their parts of e.g# root,

8t©o, lea l , flowei?t seed, fruit , bark, modified stnictyr© &TI$

thair by products as gum, reslnt ©jajdat© etct So»tl i»s Uchens,

Itoss and f ^ g l . Plant Fossils aro also tisod as iiqportant taadielnes.

tfhoro as in i odesn Syatoai (Allopathic) tha drugs are used after

selentlfie evaluation ami thereafter synthaalsed for serket needs,

Harlier i t has been raentioned that most of tt^ drugs of

plant origin are mil identif lad botanlcellvi but thai*© ar© s t i l l

a niffld er of drugs i#jose OKact It^nlity i s not oonf iriaed, and

considered to be controversial in nature. This has happened «Jii»

to t i ^ i r unknoim orlglnt procureissnt from abroad, vmm^ uses and

handlif^ from the reaote past, tecauea of the scanty and tiii-

authen^c litera'tore anA also due to us® of different vernacular

nacies in different Irngt^gea e t c . I t has also been iKSticed t l ^ t

the actual drugs described in the anci®tt classical texts either

is not avallabla In oi^ country or al l togetlpr a different

species is utilised in place of the original one* StHaatlraes these

drugs, because of their close resenblance in 8ppearai«:e with each

other are soimgly picked up by unskilled or untrained people

dealing in this tracte* Xf a ^ood, stem, root, b3rk» fruit or

seod etc*t of different drugs (havtog close reseii^ance «vith

each other) is kept in a gunny bag for use, i t beeches diffieult«

even for a professional Botanist or a Itia^tnaeognt^st, to give i t s

botanical identity by just having a glance • I t can be done only

when "Wie drug sasple is Identified to the laboratory by studyif^

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Ml 2 4 iw>

the botanical, phanaacognostlcal end chenilcal characters of

difforentlatlcn or else It can bs Identlflad vihan the source

plant from which th? drug is obtained Is also provided, ^rsly

by seeing the drug sample or by observing It for a longer period

In the ph tBiacy or In the market does not mean that Its exact

botanical or phanaacognostlcal Idsntlty can be made* These types

of Intricacies lead to tte problems of adulteration, wrong

Identification and even tha substitution 'Aiii -those of tt© other

drugs*

It has been noted that taost of the d rugs v«hlch are used

in this system (Uhanl) in o\xr counlary have not been worked out

thoroughly* Soma of them have been «nrked mxt botanlcally an!

some have been ^crked out only for their anatomical characters

and chsiaical constituents. Slcdlarly only lew have been tried

phanaiR:ologlcally and put for clinical trials, but none of them

have been tried at one place for the aforesaid aspects under

quj^ified persons. Moreover the work so far has been carried out

on these drugs are not in agr<miaent with each other. Qm author

specify soiae cliaracters while others differ by giving otl»r

characters. Saae is the case with coinpound fojsaulatlona -^re

the parity is not maintained because one pharmacy makes Its drugs

(foxraulations) according to Its m«i choice and mathodology based

on the literaturs available with i t . ilhlle the same prescription

(formulation) Is made in another j^araacy according to i t s own

methodology and parameters available to i t . It has also been

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noticed that a formula provelent In North doas not coraprlse of

the same Ingredient drugs in South or Vlse-^ersea, Such

coraplications havo X«3d to tho sub-standard and wrong taamifacturln?

and disparity in th© fonaulations through out th© country. As a

result of which laying dov of tha standards of such drugs bseosat

very difficult* H chemist does not have a complete data on chemlca

constituents of a slne^e drug in a single f onaulation which

ultimately causes difficulty to the Pharmacologist in ascertaining

the properties and actions of the active constiti^nts preaent In

th9 drug*

For the convenience of research workers engaged In this

field i t is important to give \»xe the narass of the drugs vihlch

are used in Unani system of cisdlclne v«ith their botanical,

vernacular namas ami the parts used* For this a conprahensive

l i s t of the drugs, used at present In this system. Is appended.

(See appendix - A ) , giving their most accepted botanical,

vernacular and iingllsh names* l^re It will be noted that s t i l l a

rmmbar of the botanical nataes given In the l i s t for a particular

drug Is also given for the othar which causes confusion. Soraetltnss

the vernacular names and their spellings (due to pronunciation)

lead to such complications, conftislons and doubtful identity of

the chrugs. All this need confirmation*

Before Initiating the actual research work on the aspects

discussed above. It Is essential hew to review the literature

available on this subject In our country. It Is worth n»ntlonlng

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that nest of the work available on the swhjsets cio not ta l ly with

each othBT and seora to be copied from tho oane source* Thsse are

the corapllatl<ms based on published papers, personal Inferraatlons,

and other ynauthentlc published and unpublished s^Jrces. If one

publication deals with botanical idsntlty of the drug, ths other

descrlbas the vemacuLar nmmQ (based on tfm namas given in the

texts) and also on the basis of t te Infoaaatlons given In different

floras. At one hend few of the books deal only vAth the enatondcal

aspects of leaves or any other part, on the other hand few books

c'eal only ivlth chemical 'i^pscts ofiiw drags* Ttougb a l l t h e ^ books

£nd puM.lcations do not throve light on all the aspects of the

etendardlzatlon but they deflnltaly provide Infonaation to ease

the research viork on those drtjgs# Ghly recently few scientists

in different Hesoarch Institutes arei Universities have taken up tv^s

difficult task &m dolag standard ivork by publishing thera In

different journals of the country and alsc; abroad. The liaportant

«iork so far carried out by the qualified scientist on tha Bark Drugs

Is given in the App6*ndi: « 0.

In Unanl Systsra the^ro are a nuabsr of drugs which are used

noii aid then In a ntiaber of con soimd lorEailations are s t i l l

unidentified and considered doubtiltl as far as thsir botanical

Idtentlty Is concerned. Sooe of t tea are jaentlonta herei

(1) Gaozabant A nuabor of botanical naass e.g. Qnosiaa, ^nchusa, Borago etc* are given to I t .

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C2) l^lSE* I t Is a alxttiTd cf five to six species of Llchenus and Is gpnepallv Identified ^3 ^.Sfsllgi 9orlata> vjhlch Is a eopreet Identification for ths drug C|^,rlla and 13 ono of ttsa Llchan, (oi»t of 5»6 spacles) taentiomd abov9*

POT th i s & nusater of botanical nsnws ar© liven in t l ^ l i t e ra ture a, #hlux-antlius BtetJilola e t t . given in the l i t e ra ture 3,g# Lepidiura

To tMs druq various Idomlflc. t lons are qlvon e,g* Abies, Taxus i»nd Haco«rtla e t c .

(5) ^^rambadt For this also dlffuront botanical naraas v l2 , Carcuma, Aconlt«ni, Uelphlnlum e tc , aT& given*

(6) i^g.i^d SaUX^t jgOFf^a jaiypat huta Is ttie genarally accepted botanical nsiaa for th is drug. Other naajes given to i t are Nlarsdenia and D?i9rculind e t c .

(7) Jadwar.t are the general Identification given to th i s drug but according to claasical litftratuaf© the ldtentlfic«jtlon to I t should ^ ZjDdottry*

(9) Bggtol,? tm types of arahml are iisjed. But which onf Is correct la s t i l l not kno'.«m.

W ISiU22S!3 ' Actual Idintif ication of thi* drug la not y»t kno^^t but used very comiaonly*

Like th© above drugs thfi re am many othar v^lch needs

confirmation. In ro ny scient i f ic I»cie5 a single plant is described

to be used for many ailments, sinillariy dlffomnt parts of the

single plant are doscrlbad to be laediclnal. In n»3t of the Unanl

books sonietlne laef of tlTO ifdant Is dascrlbwd MdUlnal and some­

times tha roots of tha aaiaa plant i s descrlb0«i to have ratdiclnal

Page 34: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

pmptxtk^n* tt $» ilfto m^A ttiat m»m iimm INrth tht tibmm

pat%M OS •v9n mox« are rtportttd intdlelnal* Thes* am toai of

1^ iii>tlc»«liM> liitriGa6i«ft found vasf coiaaonly tn Hn tftxH

wNleh has ami» tht i<iifrlili6iitloyi and standardization vmm

dif f ioolt «id oonf usiii9» Ttds cm Is zootlf lad only whan «li

thtao drugs art Blmtlf «id aK^dually i«»rl»d oitt aothtntieolJLy

undo? thi 9iidanea of oos iltOfitt qoaliflod md olnotzo worfaifs

fO]p oach dltelp2.in9*

In tha ll#it of tho ahovo aantiomd porobloao tho inrosont

study has haon taktn tip to vmnk out only sons of tha iaportant

bork drugs usad in ttiani Systoa in ordtr to aehiavo tha goals

of standardlxatlon as It is not p^sihlo to oovor all tNi aspaets

of all tho hark dru^ in a lloltod piriod of tina* Tha fofort,

only tho iaisortant anatoale^ and ehooioal i^raotars oiongwlth

ths dif farontlatlng oharoctars nill ha nnxtkfiA oot so that «

systanatie study of thaso drugs oould ha dims*

Page 35: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

(3) pim Qp m^

To carry (»it thi r«so«RBh WKsk <m ths said ptoblta thi iiaportant Bark Orxs^ used in XirK an Systems of «4Miielfi» (Ukianl) will bt peeeiixed from the inarkirt or from the natiural fourct as tha easa tsay be. tha aettial itudiy idl l lio earrlad mit on thi follo«ilii9 lliiett«»

tha axaot totanleal Idantiflcatian of tha drug ylalding plants MUX be glvan alongvtiyi tha datall daacrlptlon of MDSjE loaieal Charactara, Synonyiii@s» Hal^t and ftebltaty ftUA of Qecttrxsiica aid thalr plao» of avallabUlty and pvoeuranaiit aceordlna to tha taxanoislcal mrm and the Itqsortant floras on tha stthjaot*

(2) ftyxffacoqM:^iC||?^ ;< afft H,< ^Affli I) (fTtida dz^si tha B»rk drugs iidll ba workad out giving

thilr Maeroseopleal (ixtamal) eharaetars y;la Colotir* Si2« (Xangth and diaaater in cos.) and fraetura and flo3tir@s ate* and #ite illcrotcopleal (Sntamal) Ghstactera y ^ , Call StmotuxOf OfU Contents an(i the laoresaniBa Analysis ate*

i l ) Sn^a^cal, C^y^ll^i^,! tha tnportant el^meal constituents so far knOMn i«lll ba given in a table fora and a general diaialcal screening ifill ba ^ne by po fdirlng tha drugs mvi tasted f<ir it^x^etant idtntlfylng oheid eal eharaetars«

i l l ) %^:^S,ttt^s, ,flirt, ,ftd , yrffi(||t Xf any sutoitlttftas or an adulterant at all la InoMti for ^le genuine drugs will be worlcedout giving Its detail botmleal and pharaseog^ nostleai aspects as <lone for the genulna drugs.

iv) l^m* W^mh „lfl „ Aff W Y*» »*«Kly wUl be carried mxt m (a) I eralgn Organic iiattert (b) mtal Mh Contend (e) Acid Insoluble Ash (d) Alcohol Soluble Extractives (e) Water Soluble Bxtraetives etc* according to the laithodo^ logy givan in the Inc&en Fhazaecopeeia (21 )#

Page 36: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

m 30 m

(4) mSTHODOLQay (Hattrlals md jynthods)!

t!# fbUoHlng tsBthodology wlU Im adapted for t ^ f)r«s#fil study*

i} l^^ni<.^„ IdBpi l tYt Th» BatanlcaX tdsntlty of th® drtig yielding plants vdll bo ikins aeeoidln^ to th« noroft of taxsnoaioal eharactdrs !•«• by studying tlii» flositrs mad othsr plsnt ehsraotsfrs given In thd dlfforsnt floras aid taxanoi^cal books*

^) ^it^LJSSi33L^ i^ssh samplds (at different stages of growth) 0£ ths aarkst spaol^ns of tha bask drug tiUl bs fxroousod farom dlf Isront locality and souzeos In ^n eotmtvyt 'nd «A11 bs studied ibr thslr li^iortant Mloroseoplcal eharaotsrs* ffreo hand and i&omtosile ssctlons will bs out far the study of Ulezosoopleal characters* Tht staining and mounting will be done aceorcUlng to the usual f)lant islczotechnlques (12 )§ Mloro-4 ! mleal testing will be done on frssh sectlom according to thfi nffthods laid down by Kay ClS) Johansen (12), and trtase (27)* For the study and tl» oeasureBiont of the Isolated tissues and eel Is small pieces of the fliaterlal froa different parts of the bark drugs will bs oaeerated separately in Schultx's fluid, ? shad with water« teased and fsounted in glycerine. The representative dlagrans will be drawn with th8 help of Caiasraluclda* the powder of the bark drugs wHl be examined imder tho ultra«vlolet light according to ^le sKthods described by Chase and I^att (4) ^d %\n florescence ehazteterlstics will be recorded In Urn foai of « tablo*

Page 37: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

«iso9t naiMs mtfi distrilmtijmU <lovt» of £ticil«« Mitiistiry of

Ca) Ahaad, R.y. and Srlvasta¥3» PX#, i977, /^,N^,,|!«.MI-„MatjLor^

and utiXlsal^aii of Mtc elfiiiO^ md /^oaatic p%&tMp Bttfrltmal Hasaaseh £.ali«, Ja rau « Tanif i90«l5$*

(3) AJIHI^ « . A . , X9a» tif^iA or Aga^ Ifidlclng, l&wtt. of mat* of IHdiolnOt Hit* Otltil*

(4) Gliastt C«E» « i^ JPrattt H«« i949t <7* Aiaar* Piara* Ms* (soo*«d!i*)» ^ t 9^«

<S) Cliopsa, R«fl*» Ha^^t S*L« and Choparay ItC*^ 19d6» tp>oa»agy of a^l,art ^lol j i ia^ , ^B(fc% CoiattoU of Solontif le md Indti^trldl Eosearoht Hmt Qalhi,

Ptrt* Ii1^»t Ca].ctft!%a*

(7) QL^^t ^ « i i ^ F*t iyi<*3rt ¥»S« WMI arady^ UR*t i970» ll^l^^&^t^Xti Sl)EtH Odin* i'Mlmh ^* ^ f^MgtiTy fnU (i«Xptiia*

(8) i)of, K.!,,, 18II6. lV^,^ff^i^ mm> ft, l¥l»^t I ^ U a r . Spinkia & Co*^ CaXoi»tta*

(91 Kantiuri^ S*0«H^» ie9t (Xm? II*K ^930i taarlyiiia Qmia>^l^liaikli

(XO) lytni^aPt M»A»» XW4» A Hand BQ<a <^ fliaraa^eanooy. f l ra t Ofte.* CoXXega of Phmameft Kasl^rlsa tiadioaX CoXXofa, tUnipaX, IQasnataiia*

Page 38: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

(u ) iy«r, K.N» md nokamnk^ %, 4960, mmmmmsLMMmsst^

Co*g Inc. nmt 'mtk^ IBZ*

(13) lesbianiddln, M«« i929t Kltffib.*itl AEl«tfly ( t » ^ ) * Vol* ZX

C ^ , I ,. . I, ,;, t A9ao» tarSiiiaa-i-»l^liii?» Vol* 1«IV, !:feifta»i4iU

Tindall & Cox, iondon^ 14»

(1^) ¥hm^ A«, 4906, I^,igM^W^,«8> ^ l » II , t^wal ICl8ho£» l»r«st, y^lcnowt 266-328*

|17) Kirtlkar, K*H* 4Uvl Basy, B«0*t 1979, i|^lwi |^4iej^ial Pla|fit». Vol* l>>3y, !^|}ift* 0(ln«t Allafiabsd*

(18) Ktttuablahl P . , 1962, ^Sm% , % # ^ ,¥i4M%ffif ^^^^^ l ^ p a n s ,

m^ otibi«

(19) y i t i i . A*, i^m^ ift¥,»i#-#%lTO?»flt^^if;y.ii <«»*») »p«n 3ool4ty, Caleittia*

(20) Hadlwml. A.K., 19!W, l ^ j U M k J l ^ i a S ^ ^ ^ l dl ,a. Vel« I & H , Third t ^ » , l>opula7 Boi^ Pep%#, ioa^f*

(al) Pfjajnaac BfOtia of If^ii^ (Tht J&iiii«ii Pharaict^poola), 1966, Soo* odn*, tb» Nisfia^r of Pul^leatloii, <km%* of India press, Oaihl*

(22) S«S4, »#, 1966, y.aidar<l ,^d^,4 R ^ ,: * Vol. IV, Karachi.

(23) S*iah, C»S» and (^kiry, J*S« i9?i , A fojft Boo^ of Pharaaig<NiROiy> first odn*, ai»8srs a*3* Slh^, AhMNlahad*

(2*) ShajPiff, H.t I9f6, hP^P^^k^i^M M%m lYBWySf Jtt Roprt. •dii«, P»riodioal Sook %ai3t|r, I3i|iradi»«

Page 39: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

- * ^ ' ^

:n 125) S JJ gas*. ?• iW3, ^M^^^ l., I ^ ^ l l . .I^^E^WEyt ^»st Indian

(261 Taeishdlsy V» antl Orar, «• , Xfl^t | ,<iif;a, i ^ S<y«#. V0l.I»I^, Otto iSooItx ^ti^piariatf K9tnl^t*to tS/B^«

(Zr) Trtas»» Q^B*, 1966» f>,?rtt . fqft%,ii, lffy,gffmff«iyf ^ ^ • *»• • SaUliwrfi, TiUidftil and Cai»U S»td» lmv&m»

(23) itolildt A* and Siddl<pl« aH*» i9a» ^ttfryy ol^Jj^qa* witti partieulair xmf9mm» to l ia /yra^ (linanl) lAidicino and Ayufvoda, £Rstt* of (ll«t« ^ M»di* 411 mdiml Btsaasehy mndai«d ftiUdin^St DtXM*

(29) iaatl» 3«/i*A*H.t i»3?.I1 ifl fa"y3UiAgab. Watt I* Vol* 4, !«»*at Shain-«t «iAtll>lia^ %»^mf U«ii'«ii^938 f p >!faL*f3?a,fef> l^i^ 3, Vol* St )l(3«4» ^asii^l««^ti^at l«a|iorat 9»t8*

. . F ^ W ' m^fe-ol-Arafe. Sp. m. . vol. t , IKJ.9. Ttbb-«1-Jadld^ l«ahos«ii Bm^*

(30) WaU« 6*t X972» 1 ^^^^ M ^%. ,^,<lfflll*..,tPp<l^^ff M W^* Vol, &»DC» S^« Biprint^ CoffW l^llioation« Dalhl*

(31) 1 ^ ]f<^U^ i f In4,l^. (^« Wafearlala), 19# , Vol. I^IX, CouncU of Selmtlflo «nd Indtistrlj^l Tlttioazoh, W^l Sid* Hoad* 1 19 Saihi*

Page 40: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

W /^ .^PBHP^pa^

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CB> utst Of WB waxKmn: wm, tmm mm m BH

« asislftssiaslii «i < * BBi 2* A< gM i ^ b l ^ mild* BirlE

9* A lifiggU | «^<ic^ BBiiiti* Birk

6. alHSQlfl mlP^^^M ^*^* ^^^

8* ^Ijiiff^p^Am M l a m A* > ^ « Bark

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2« |»ttn i UiJlStfi * ^^* Bark

^4- jjc^wnl^ |jas«iJs«p«ig* wok ^d* ^lUlcarga fflarcoi^v^if, Vahi* Bark

16* Cff^^opl,^ IF;oc«rf (Alt) R.Sr* Root Bark

18* Cai lsaa fg>r,j|r <ite% Ujtm* Reot Bark

19« ^Sfi|& IISiillA 2«inR« l^ot Bark

20« SiflfOT^^a ISiflU «»•» ^ Sbtrm. Bark

^* O^p^ if J M (Bttrs) Msrr* f^ot Bark

23* (j tr^y y,<ti6.% Linn* B«rk

^ * dT^ttitteya f^wiid^ IMnti* Hdot Bark

Page 73: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

(U)

29» C grod^drua if^ncat^ (l.inn«} mm Boot B&tfk 26* Cj lytflspla ^ t n a t t a Uim* Root BarlE

28 . 9S2Saaaa l8l52Qyki.a»«^Wam, Bajfk

30. Q^ff1i ??ycayw SiS^k ^ « ^ * Bark 31* %ftlyii^a indi^^ Um* Baxk

^ « ^ , 3 ^ ^ ll^ac^l,« (!.i])n«) Siflngljft Bazk

33* fXn^ ,„feg|ia» rff,lr«, I-lim. Bixk 3** , c« , h^g l<** Linn.f * Tioot Bark

3S* l l S i a ffiA^^^^ J* nn- Bark 36* a a a ^Sl!tlt Roxb. 8axk

37. ^,FPMf. W^m «^i«» S k 38. gKaiJaaS&Sa* I-^n* r<i^B»rk

39. q^s.tYPli^ W¥Pm^ ^ ^ n * Bark

^* Il9 . rif .nff ?X^\^!t^^^.^^ '^X Bark ^* l^^lliS* toq^^^^* CLlnii.J aactelds. aark

4 3 . mMm l^^\P9^ifm^^* JftJti-^9* Bark

45. g A M at»< ay*c|l Lliw. Root Bark

46 . a s i l I&SSS& J*i«»» Bark 4 7 . MljChaila ^|yafpa^a Linn* Bai^

48» ^V«W80,m alSOai J- nn* Bai?k

49 . mkmi^l^JdSSSi^^* B8rk

Page 74: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

am

Si* SSldi^ ||l|fdl|<5U!| UiH Boot Bark

»«• !ar.»yail %1» %(gm^»m i^^^^ J SUva h^i^ Boot Sark

^ * <^i^^o« Aft Uff a v»n(t* Bark

^* ipmm^n atoasa Ctsiw*) mtr* sark si^ tern ss£aaaA^R£.o» »«»• sark ^ * ,i:t»;m '3PM?l i<? l <ffl ^«xb« Bark

60« SIffiSSIS lin^^torV ollv« sark

^ • amilft ilCTfltmrg i-««k. Bark

62* M i a mSBSM. >-^* Bark

^ « S.«raca , a ^ « (i^cs^O^*.. w^ld Bark

< « ,a. l?Wiyi. mm^if}^?:*, OLlnn.) I^rs* Bark

«»• ^aabania J^^SPL il'^m*) MCVY. mrk

^ » ^i^^a^ «y>biiaita Gaortn.l. prk

^ * g>P0iyiS,as Jlii patfli,, t»tra!> Bark

^ * S|tg»i^ui f ^^ Loiir« sark

70. ^.te:c,l|ff& «m>n<#<^ J-^n* ''Oot Bark

7 i . §Bl y2£08 sgcgawa T^xb. Bark

72. l a s t o a J&SQ^ Unn.f. Bark

73. I^,wU*» lgy ii ,«'fc» (a.Oai)Stt«« Bark

74. y r n ^ l l , ^ , BM^ HS ^ Bark

7S« Zanttyxyliwi a^taai Hoxb. 8ai^

76* ZiiYolyt i s d 3 ^ ^^ « S^^

77. Sl^igf^.. xyloearPBg WUld. Sark

Page 75: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

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Page 76: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

CD) HSFSRENSS LIST OF tm H3RK D<m OK »IPK ITUGS

1* Afisari, I4.S* «nci (li|]it«» H»C«. X97Jlt *Phartt«eognottlcai Studlod on Capparlg Ktyjatitcl Urm*. Jour. n«s. Ind. SPd., V o l . VX» !*>: fV p . JilS. '

2* B38U, ft.K* and Jonoja, A.H*^ i949« *iChiale«l IhVistl^ation of fgtwia ffi[t»4fl?i mla t«li»i.«» bid* J. Thaim., vo l . XX, 1^.6^ p» 191•

3. atattaoharyay X«C. i9il« ^Hiamacognostic^Jl Study of Chattia Bark M j d a m j N I I ^ ^ ^ S r A Vol. XI (2). 1^^»jr . of Scl»

4 . Datta, SX« md BaX. S.N.. i949 apHanaacomiostlcal Studlaa on IQarehl Bax1c*» 1^« J . Phasaaeyt Vol. Vfl, ^)o.4, p. 1X3.

5 . 03tta» S.C. and BaX, S.H., X946. •fhaxiMieognostlcaX Stodlat m Cinehona*, Snd. J« Pha»aey, Vol. VIZX» Ho.2, p. 85»97*

6 . Qupta^ L.P., Son» S«l « and Udypa, K,H*. X976, apbamacognostieaX and PharaaooXogieaX Studiis on ToanAnalia aritina*. Z^. J . Pharaacy, VoX. ICXt ^-^v P* ^^*

7. Oupta, R.C* «id KapooTt L.D.« X97S "ThamacognottlcaX Studlat ^•Strlrtj^jj^t m ^ ^ t e ^ m i m B»nth.-Sttni Bark.

8. Oupta B.C. «nd Kapoor, !.«D.,X973 *l^naicognostle Study on «Stris1v.XX* AXbixxla Xelabaok Banth •» Stan Bark«t J. Has* Xmd. Mid,, Vox. VXXI, Ho. 2 , p. 29«

9« Gupta ft E.C. mvA Ktmas^ L.D.t X974t ^Iharnaeo^nostlo Study tm *Siriah « III* AXblz^ia pjeoeara Bash • Stan Bark*. J. Baa. ind. iHd., Vi^. IVt NO* 3t 9* ^ «

XO. iiBhta« G.B. mi Piil^l^ C*H*, X9at. "ChscilcaX ExaffitHatlon Of v S . ^ ^ m l ^ ^ l ^ * ' ^ ^ — Ro«&t*t W . J . Wiamiacy»

XX. mtra, R. and Kapoor, L.0%, X9?X, ^ Goa^ratlva Pharaacognottle Study of COBMireiaX iaa^lea of tha Varu Bark*, J. '^es, Ind. Sled., Vol. VI, No.4» p. X7S.

X2. MXtra, R. and Kapoor» !«.0«, X974 "Fhamaeognostie Study on tha Boot Bark of C^taayai nirva;La. ffm. (Varum 1% J. Ras. Bid, IlidX.t Vox. XX, NO. 3^ p. 49*

X3 antra, H., «id Kapoor, UD. X974, ^PharmacognottlcaX Stt»ly cm *PXakiha l u staa Bark of Pict» tslala Roxb«. J. Raa, Ind. iHd., Vox. IX, NO. 3 , p. XX5. * * ^ ^

Page 77: Pharmacognostical and Botanical Identification of Some ...ir.amu.ac.in/6927/1/DS 317.pdfPharmacognostical and Botanical Identification of Some Important Bark Drugs Used in Indian System

Hi)

14* 9rak«fth» A« and Pratsd, S*. 19699 "Phiriafteo^ROstleal Studies m th* lark «rf .SSad^Sa l n t o » V * i i t . (SirmiaiEa}*, Irid. j .

i5« Praieath. A. and i^asadt S*« X969t "PharaaeodpiKistieal Stud U s en ttw Barks of fiflli£ iSSnbS^ ^^^« (BUvdJ»« Xnd. J, Phaita. p« 97#

16* I¥a9ad, s*, Jain* V.K* and mtra, R«. 1967, •Phazsacognostlcal St»dl«s on tha Bark of Bohltak «• Oadi^ l^shpa, Tacoatlla ^M..<fi^ isean", 2 , 1 , J. Ra«» Ihd, Biwi., Banaras Hinchi

,vtriltf« 8anara»« p* 25*

Banazas, 317«a25»

18* l^asad, S« and Kaul, P.fl*« I9S6, <*lNianieeo9io9tl€al Stiidiaa

19. Prasad. S. and l%:aka»h. A. 1967* Pl -J isiacoonoftleai Stodlas

20, Pra;? f«, « , Oupta, P.IC* «nd OiattaetiBs^a. I X . , 1960. Pharoaoognostlcal Studies on Kohitak Barki l^rks of Ervttyrtna

#agloqata Linn* V»T, erlentstls (I.&V1*) MorlU Aaoora r^itttka m^t* Vol* 19 C, m*4^ Jour, of Sol & iSmmt* Has, p« 107«

21* Pzvshothaisan. K*:<« and li&trajant H»K«, 1974 ^O^Mieal Exaialna. tton <tf Pata^ (Starsosparaiia tstraoonua Dc.y*. find. J. I'tiara.t p. 107*

22* Baich«idhuri, H.tj* and Kayfil* E.H*, 1976, "Pliaroiacoffliostlcal

23. Sobraajnian* S«S» and Raaakrisfinsn, S« 1968« ^ Hot* on Chaitlcal Olf fardfitlatlon of the Barks of Dy^on^alat^ mid D* regis,* Ind. J. Uhana., Vol* 30, No.9, p# 2iaU