Pharmaceuticals

DNA RECOMBINANT

•DNA MOLECULES FORMED BY LABORATORY METHODS

•FIRST LICENSED DRUG IS HUMAN INSULIN

Vaccines help the body fight infectious diseases. Traditional vaccines may be attenuated form of the pathogen, that is, live pathogen is weakened through chemical or physical process (e.g. vaccines against measles, mumps, polio); whole pathogen that is completely killed or destroyed chemically (e.g. vaccines against flu, cholera, etc.)

VACCINES

•FIGHT INFECTIOUS DISEASES

•WEAKENS BACTERIA

Advantages of a DNA vaccine include the following:

• Plasmids are easily manufactured in large amounts.• DNA is stable and it resists temperature extremes so

storage and transport are straightforward.• The plasmid does not replicate and encodes only

proteins of interest.