Pharmaceutical Analytical Chemistry Department specification analytical.pdf · highlights the basic principles underlying each experiment. Week Experiments 1 A redox ... Pharmaceutical

جامعة مصر للعلوم والتكنولوجيا Course Specificationلوم والتكنولوجيا جامعة مصر للع

وحدة ضمان الجودة2016 - 2015 ئى والتصنيع الدوا علوم الصيدليةة الكلي

Pharmaceutical Analytical Chemistry Department

جامعة مصر للعلوم والتكنولوجيا Course Specificationلوم والتكنولوجيا جامعة مصر للع

وحدة ضمان الجودة2016 - 2015 ئى والتصنيع الدوا علوم الصيدليةة الكلي

جامعة مصر للعلوم والتكنولوجيا Course Specification جامعة مصر للعلوم والتكنولوجيا

ضمان الجودة 2016-2015 والتصنيع الدوائى علوم الصيدليةة الكلي

PHCM101





1


A. Basic Information

Program(s) on which the course is given Bachelor of Pharm. Sciences

Department offering the course Pharmaceutical Analytical Chemistry Department

College offering the program College of pharmaceutical Science & Drug Manufacturing, MUST University

Dept. responsible for teaching the course Pharmaceutical Analytical Chemistry Department

Academic year / level First level , Second Semester

Course title General Chemistry

Course code PHCM 101

Contact hours ( credit hours ) Lecture: (2), Practical: (2), Total 3 credit hours

Course coordinator Prof. DrELZayinyAbaid

Major or Minor element of programs Major

Date of specification approval 1/9/2015

B. Professional Information The course aim and intended learning outcomes are based on that mentioned in the program specifications, with more course-related specific details. 1. Overall Aims of Course To teach the student fundamental chemical ideas including the mole concept, atomic structure and periodicity of properties in elements, photon energy and its uses in pharmacy, medicine and instrumentation, introduction to quantum mechanics, theories and types of chemical bonding, energy and chemical bonding, chemical kinetics..



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2. Intended Learning Outcomes of Course (ILOs)

a- Knowledge and Understanding:

By the end of the course, the students should be able to:

a1- Recognize Structure of atoms and molecules.

a2- Describe methods Chemical changes

a3- Understand fundamentals of Energy; photon and thermal.

b- Intellectual Skills

By the end of this course, the student should be able to: b1- Asses in chemical changes.

b4- Asses Anticipating molecular interactions and dynamics

b5-Expecting material properties and behaviour.

Professional and Practical Skills:

By the end of the course, the student should be able to: c1- Apply the given techniques used in medical diagnosis and treatment e.g.MRI, Photodynamic

therapy (PDT).

c2- Build a suitable methodology to solve chemical problems. C3- carry out all stoichiometric chemical calculations and finally can calculate the

purity, yield percent, reaction rates, enthalpy, entropy changes during chemical reaction.

C4- Demonestrate skills that enable him to use chemical laboratories

c3- Grasping the instrumentation of photon- based methods. c- General and Transferable Skills

By the end of the course, the student should be able to: d1- work effectively both in a team and independently on solving general and inorganic chemistry problems. d 2.communicate effectively with his lecturer and colleagues.



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3. Contents

Lecture number

Topic

`1 The mole concept. Naming inorganic compounds. Mass spectrometry.

1 Photon energy and its applications. Lasers and laser techniques.

1 An introduction to quantum mechanics.

1

Photon – based techniques of analysis, nuclear magnetic resonance (NMR), electron spin resonance (ESR) and magnetic resonance imaging (MRI), X-ray emission and X-ray fluorescence, infrared spectroscopy, neutron activation analysis.

2

Chemical bonding, types of chemical bonds, theories of chemical bonding including molecular orbital (MO) and valence bond (VB), and VSEPR theories.

1 Electronic transitions in molecules, bond orders calculation, singlet oxygen.

1 Effect of chemical bonding on material properties; graphite, clays and zeolites.

1 Redox reactions. The formal charge concept.

1 Energy of chemical bonds and enthalpy changes. Thermochemistry.

1 Chemical kinetics. 1 Nuclear chemistry and its applications.

Practical Prior to each experiment there is a tutorial for about 20 minutes which highlights the basic principles underlying each experiment.

Week Experiments 1 A redox reaction caused by light. Laser and X-ray diffraction.

2 The mole concept and the determination of the atomic mass of a metal by gas evolution



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3 Density of a single crystal by floatation method 4 Study of heating and cooling curves. Application of Gibb's phase role

5 Volume changes upon mixing. The salting out of ethanol and water. Encapsulation of organic chemicals within a starch matrix.

6 Molecular weight of a polymer from viscosity measurements. 7 Ionic equilibrium. 8 Miscibility as a function of temperature: water- phenol system. 9 The catalytic decomposition of hydrogen peroxide.

10 Kinetics of the reaction between iodide ion and hydrogen peroxide in an acidic medium.

11 Thermochemistry 12 Preparation of colloidal iron oxide nanoparticles and its destabilization.

4. Teaching and Learning Methods 4.1- Lectures 42- Practical sessions

5. Student Assessment Methods

5.1. Quiz to assess efficient study.

5.2. Written exams to assess knowledge and understanding as well as intellectual skills.

5.3. Practical exams to assess professional and practical skills. Assessment Schedule

Quiz I ……………………………….…..Week: upon course progression Midterm…………………………………7-8th week Practical exam…(2)………......................12-13h week Final exam……………………………….14th week

Weighting of Assessments Mid-term examination. 16.66%

Final examination. 40%

Practical examination 30% Quiz 13.33%

Total 100%

6. List of References 6.1- Course Book:

Supplied by the Department. 6.2- Essential Books (Text Books) 1- T. L. Brown, H. Eugene Le May, Jr, B. E. Bursten, C. J. Murphy and P. Woodward, "Chemistry; the Central Science", New Jersey Prentice Hall; 12 Edition (2011).



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2- R.H. Petrucci, W.S. Harwood and F.G. Herring, "General Chemistry: Principles and Modern Applications", Prentice Hall, Eighth Edition (2002). 3- D. D. Ebbing and S. D. Gammon "General Chemistry", Houghton Mifflin Company, Boston, New York, 9th ed. (2009) 4- J. E. Brady and G. E. Humiston "General Chemistry", John Wiley, New York, Chichester (1986). 5- G. Hill, J.S. Holman, Graham C. Hill "Chemistry in Context", Nelson Thornes; 5th edition (2000). 6- P. W. Atkins "Concepts in Physical Chemistry", Oxford University Press, Oxford (1995).

7. Facilities Required for Teaching and Learning

Overhead projector, computer aided data show

Coordinator of CourseProf. Dr. El-ZeinyMousaEbeid

Head of Department:Prof. Dr. Laila El-Sayed Abdel Fattah

Date:1/9/2015




ضمان الجودةوحدة 2016-2015 والتصنيع الدوائى علوم الصيدليةة الكلي

PHCM122





1







Academic year / level First level , Second Semester

Course title PharmaceuticalAnalytical Chemistry I



Course coordinator Prof. DrLaila El-Sayed Abdel Fattah



B. Professional Information The course aim and intended learning outcomes are based on that mentioned in the program specifications, with more course-related specific details.

1. Overall Aims of Course After completing this course the student should gain several competencies in the

area of qualitative inorganic chemistry that would enable him to work the

different related field of analysis (forensic chemistry ,water analysis,

environmental pollution),to be able to apply previously known analytical methods

in the different areas of inorganic analysis,and to provide the students with a

quantitative sense in chemical analysis as well as adequate knowledge on

volumetric analysis includingAcid-base reactions (in aqueous and non - aqueous

media).



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2. Intended Learning Outcomes of Course (ILOs)

a- Knowledge and Understanding:

By the end of the course, the students should be able to:

a1- Recognize qualitative inorganic analysis and the chemical reactions

involved.

a2- Describe methods of separation and identification of anions and cations.

a3- Understand fundamentals of analytical chemistry.

a4- Recognize methods of handling of basic analytical tools.

a5-Explain analytical data.

a6-Descibe theories of acid- base reactions in aqueous and non aqueous media with

focusing on their application on the analysis of pharmaceutical substances.


By the end of this course, the student should be able to: b1- Asses in the judgement on the suitable scheme for the systematic examination of

cations as well as anions either in simple mixture or in special admixtures producing

difficulties.

b2-Analyze the application of statistical treatment on the analytical results and data.

b3- Select solvingequilibria problems e.g. calculation of different ionic species

(pH, pOH, pNa …etc).

b4- Asses the result of calculation of different physical constants (pKw, pka,pKb…etc)

to solve analytical problems.

c- Professional and Practical Skills:

By the end of the course, the student should be able to: c1- Apply the given schemes for identification of anions and cations.

c2- Design certain schemes for the analysis of anions and cations.

c3- Build a suitable methodology to solve analytical problems. c4- Develop the procedural steps and carrying out the necessary measure to get reasonable results. c5-Demonestrate skills that enable him to use analytical laboratoriesempolying volumetric

analysis.



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d- General and Transferable Skills

By the end of the course, the student should be able to: d1- Practice independently in different quality control labs. d2-Evaluate and make decision to deal with different qualitative or quantitative analytical problems in pharmaceutical and biomedical fields. d3- Develop different written skills for reports or assay with standard scientific guidelines learned from this course .

3. Contents

Practical number

Lecture number

Topic

0 2 Introduction to chemical analysis Le Chatelier principle Electrolytic dissociation theory Degree of ionization Chemical equilibrium Law of mass action Solubility product Common ion Complex ion formation

3 2 Systematic examination of anions and their mixtures

Carbonate group Sulphur group Halide group Cyanogen group Phosphate group Nitrate group

3 2

Systematic examination of cations Group I cations Group II cations Group III cations Group IV cations Group V cations Group VI cations Scheme for analysis of unknown mixtures

1 2 Midterm exam

1 4 * Introduction of quantitative analysis - Types of analytical techniques. - Statistical treatment of analytical data

* Volumetric analysis - Reactions suitable for titrimetric analysis; types &



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requirements. - Titration methods - Standard solutions and methods of expressing

concentration * Acid-Base titration in Aqueous medium:

- General concept of acids and bases - Hydrogen Ion Exponent & the pH scale & calculation

of pH of different systems - Buffer solutions - Acid –Base indicators - Acid-Base titration curves & their derivatization.

- Application of acid –base titration in aqueous medium with emphases on its use in drug analysis

3 2 * Acid-Base titration in Non-aqueous media - Types of non-aqueous solvents - Titration of weak acid & base - Indicators to detect end points

* Application of Acid-Base titration in non-aqueous media with emphasis on its use in drug analysis

1 2 Final exam

4. Teaching and Learning Methods 4.1- Lectures 4.2- Tutorials and discussion sessions 4.3- Practical sessions

5. Student Assessment Methods 5.1. Quiz to assess efficient study. 5.2. Written exams to assess knowledge and understanding as well as intellectual skills. 5.3. Practical exams to assess professional and practical skills. 5.4. Oral exams to assess all types of skills and mainly general and transferrable skills

Assessment Schedule Quiz I ……………………………….…..Week: upon course progression Practical exam…(1)………......................6th week Midterm…………………………………7-8th week Practical exam…(2)………......................12-13h week Final exam……………………………….14th week Oral exam………………………………..14th week

Weighting of Assessments Quiz 13.3% First Practical exam15% Midterm16.7%



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Second practical exam15% Final exam 30% Oral exam 10%

Total 100%

6. List of References 6.1- Course Book:

Supplied by the Department. 6.2- Essential Books (Text Books) Vogel’s for qualitative inorganic analysis. 6.3- Recommended Books Gary D. Christian, "analytical chemistry", John Wiley& sons, INC (1994) Martindale: the complete drug reference


7.1- Procurement of latest edition of the above mentioned texts and othersto update the education process.

7.2- Chemicals as reagents and indicators for proper lab work. 7.3- Analytical tools as centrifuges, burettes, pipettes and flasks to satisfy the need of

students. 7.4- Computer hardware updating. 7.5 - Overhead projector and data show.

Coordinator of Course: Prof. Dr. Laila El-Sayed Abdel Fattah Head of Department:Prof. Dr. Laila El-Sayed Abdel Fattah

Date:1/9/2015




ضمان الجودة وحدة 2016-2015 والتصنيع الدوائى علوم الصيدليةة الكلي

PHCM 221





1







Academic year / level Second level , First Semester

Course title Pharmaceutical Analytical Chemistry II



Course coordinator Prof. DrLaila El-Sayed Abdel Fattah Assis. Prof. MahaAbdelmoniemHegazy

Major or Minor element of program Major


B. Professional Information The course aim and intended learning outcomes are based on that mentioned in the program specifications, with more course-related specific details.

1. Overall Aims of Course The aim of the course is to provide the students with a quantitative sense in chemical analysis as well as adequate knowledge on volumetric analysis including ,Precipitation reactions ,Complex formation reactions and Redox reactions .



2

2. Intended Learning Outcomes of Course (ILOs) a- Knowledge and Understanding:

By the end of the course, the students should be able to: a1- Understand fundamentals of analytical chemistry. a2- Recognize methods of handling of basic analytical tools. a3- Explain analytical data a2- Recognize theories of precipitation reactions with focusing on their application on the analysis pharmaceutical substances. a3- Describe theories of complex formation reactions with focusing on their application on the analysis pharmaceutical substances. a4- Describe theories of redox reactions with focusing on their application on the analysis pharmaceutical substances.


By the end of this course, the student should be able to:

b1- Propose a suitable methodology to solve analytical problems


By the end of the course, the student should be able to: c1- Develop the procedural steps and taking necessary precautionary measures to get

reasonable results. c2- Demonstrate skills that enable him to work in analytical laboratories empolying

volumetric analysis. c3-Apply the classical methods deals with the analysis of precipitating ions complex

formation reaction for the analysis of different metal ions. c4-Categorize the redox methods for the analysis of pharmaceutical compounds using

compendial or reported methods.


By the end of the course, the student should be able to: d1- Practice independently in different quality control labs. d2-Evaluate and make decision to deal with different qualitative or quantitative analytical problems in pharmaceutical and biomedical fields.



3

3. Contents

Practical number

Lecture number

Topic

3 3 1- Precipitation titrations: -- Solubility products constant. - Solubility of precipitates

- Titration curves of precipitate formation - Argentometric methods.

- Other precipitation methods. 2 3 2- Complex formation titrations:

- Types of complexes -Chelates,sequestering agents and their stability -Stability constant -Metallochromic indicators -EDTA complexes and types of EDTA titrations

application with emphasis on analysis of pharmaceutical compounds

1 2 Midterm Exam 5 6

3- Redox titrations: - Definitions of oxidant &reductant - Single electrode potential & Nernst equation.

- Oxidation potential and factors affecting it -Redox titration curves - Redox indicators *Application of redox on analysis of pharmaceutical compounds including: - Pot. Permanganate titration. - Pot. Dichromate titration. - Cerium(IV) titration -Iodimetry&Iodometry -Andrew's method & KIO4 titration -Bromometry -Periodic acid as oxidant for organic compounds

1 2 Final Exam

4. Teaching and Learning Methods

4.1- Lectures 4.2- Tutorials and discussion sessions 4.3- Practical sessions



4


5.1. Quiz to assess efficient study.

5.2. Written exams to assess knowledge and understanding as well as intellectual skills.

5.3. Practical exams to assess professional and practical skills.

5.4. Oral exams to assess all types of skills and mainly general and transferrable skills

Assessment Schedule Quiz I ……………………………….…..Week: upon course progression Practical exam…(1)………......................6th week Midterm…………………………………7-8th week Practical exam…(2)………......................12-13h week Final exam……………………………….14th week Oral exam………………………………..14th week Weighting of Assessments Quiz 13.3% First Practical exam 15% Midterm 16.7% Second practical exam 15% Final exam 30% Oral exam 10% Total 100%

6. List of References 6.1- Course Book: Supplied by the Department. 6.2- Essential Books (Text Books) R. A. Day, Jr and A. L. underwood, "quantitative analysis ",6th edition, prentice-hall international inc. 1991. * D. A. Skoog, D. M. west, F. J. holler and S. R. crouch, "fundamentals of analytical chemistry", eighth edition brooks / cole-thomson learning, inc. (2004). 6.3- Recommended Books Gary D. Christian, "analytical chemistry", John Wiley& sons, INC (1994) Martindale: the complete drug reference

6.4- Periodicals, Web Sites, etc Different pharmacopoeias (Egyptian &british) Merck Index.



5


7.1- Procurement of latest edition of the above mentioned texts and others to update the education process.

7.2- Chemicals as reagents and indicators for proper lab work. 7.3- Analytical tools as centrifuges, burettes, pipettes and flasks to satisfy the need of

students. 7.4- Computer hardware updating. 7.5 - Overhead projector and data show.

Coordinator of Course: Prof. Dr. Laila El-Sayed Abdel Fattah Assis.Prof.MahaAbdelmoniemHegazy


Date:1/9/2015




وحدة ضمان الجودة 2016-2015 والتصنيع الدوائى علوم الصيدليةة الكلي

PHCM 222





1







Academic year / level Second level , Second Semester

Course title Instrumental & Applied analysis



Course coordinator Assis. Prof. MahaAbdelmoniemHegazy



B.Professional Information The course aim and intended learning outcomes are based on that mentioned in the program specifications, with more course-related specific details. 1. Overall Aims of Course

The aim of the course is to provide students with the basis of the different methods of instrumental analysis. The course also qualifies the students to make use of the knowledge of analytical chemistry to be able to analyze water.



2

2. Intended Learning Outcomes of Course (ILOs) a- Knowledge and Understanding: By the end of the course, the students should be able to: a1- know and use potentiometry in analytical chemistry. a2- Understand UV. Visible spectrophotometry. a3- Identify Luminescence spectrometry mainly spectroflourimetry. a4- Realize flame emission and atomic absorption. a5- Understand the application of different techniques in the analysis of water to be aware of the validity of water to suit different purposes.


By the end of this course, the student should be able to: b1- Distinguish the most suitable methods for the analysis of pharmaceutical compounds. b2- Categorize methods for determination of certain compound in a multicomponents mixture. b3- Interpret the outcomes of different experiments


By the end of the course, the student should be able to: c1- Practice sample analysis with minimum guidance in laboratories dealing with quality control in pharmaceutical industries. c2-Analyze pharmaceuticals & chemical substances. c3-Analyze water samples. d- General and Transferable Skills

By the end of the course, the student should be able to: d1- Practice independently in different quality control labs. d2-Evaluate and make decision to deal with different qualitative or quantitative analytical problems in pharmaceutical and biomedical fields. d3- Develop different written skills for reports or assay with standard scientific guidelines learned from this course .



3

3.Contents

Practical number

Lecture number

Topic

5 3 1- Water analysis - Uses of water for different purposes - Different sources of water - Physical examination of water - Chemical examination of water - Pollution of water - Oxygen absorbed - Dissolved gases

3 3 2- Spectrophotometry - Properties of electromagnetic radiation - Wavelength, frequency & wave number - Monochromatic light & polychromatic light - Interaction of matter with electromagnetic radiation - Chromophores&auxochromes - Beer's Lambert's Law - Different factors affecting absorption spectra (pH, effect of solvent, temp., dilution…..etc) - Colorimetry (Standard series method, Balancing method) - Instrumentation (Source of light, wavelength selector [Filter, prism & grating], cuvettes, associated optics, detectors and recorders) - Deviation from Beer's Law (Real, instrumental & Chemical deviation, stray light)

1 2 Midterm Exam 0 2 3- Spectroflourimetry

- Photoluminescence - Resonance florescence - Stock's shift phenomena - Theory of molecular fluorescence - Quantum yield - Radiationless deactivation - Excitation & emission spectra - Quantitative flourimetry - Factors affecting fluorescence - Instrumentation - Application of spectroflourimetry.



4

2 4 4- Electrochemistry - Potentiometry (Reference electrodes, [N.H.E., Saturated calomel electrode, Saturated silver/silver chloride electrode], indicator electrodes for redox, complexometry, preciptimetry and neutralization reactions [Hydrogen electrode, antimony electrode, quinhydrone electrode and glass electrode], voltage divider, potentiometer, salt bridge, liquid junction potential, end point determination and applications.

1 2 Final Exam

4.Teaching and Learning Methods

4.1- Lectures (board and data show) 4.2- Tutorials and discussion sessions 4.3- Practical sessions


5.1. Quiz to assess efficient study. 5.2. Written exams to assess knowledge and understanding as well as intellectual skills. 5.3. Practical exams to assess professional and practical skills. 5.4. Oral exams to assess all types of skills and mainly general and transferrable skills

Assessment Schedule Quiz I ……………………………….…..Week: upon course progression Practical exam…(1)………......................6th week Midterm…………………………………8th week Practical exam…(2)………......................12-13th week Final exam……………………………….14-16th week Oral exam………………………………..14-16th week

Weighting of Assessments Quiz 13.3% Practical exam15% Midterm16.7% Second practical exam15% Final exam 30% Oral exam 10%

Total 100%

6. List of References



5

6.1- Course Book: Supplied by the Department. 6.2- Essential Books (Text Books)

"Vogel's textbook of quantitative chemical analysis" fifth edition "Fundamentals of analytical Chemistry" Skoog& West "The chemical analysis of water" second edition, Hunt & Wilson " R. A. Day, Jr and A. L. underwood, "quantitative analysis ",6th edition, prentice-hall international inc. 1991."

6.3- Recommended Books Gary D. Christian, "analytical chemistry", John Wiley& sons, INC (1994) Martindale: the complete drug reference

6.4- Periodicals, Web Sites, etc Different pharmacopoeias (Egyptian &british) Merck Index.

7. Facilities Required for Teaching and Learning 7.1- Procurement of latest edition of the above mentioned texts and others to update the

education process. 7.2- Chemicals as reagents and indicators for proper lab work. 7.3- Analytical tools as burettes, pipettes and flasks to satisfy the need of students. 7.4- Computer hardware updating.. 7.5 - Overhead projector and data show Coordinator of Course:Assis. Prof.MahaAbdelmoniemHegazy


Date:1/9/2015



جامعة مصر للعلوم والتكنولوجيا Course Specificationجامعة مصر للعلوم والتكنولوجيا


PHCM521





1







Academic year / level Fifth level , First Semester

Course title Chemical Quality Control of Drugs



Course coordinator Assis. Prof. MahaAbdelmoniemHegazy



A. Professional Information The course aim and intended learning outcomes are based on that mentioned in the program specifications, with more course-related specific details.

1. Overall Aims of Course The aim of the course isto provide pharmacy students with basic principles and practical experience of the chemical aspects of quality control & quality assurance of drugs (raw materials & drug products).



2

2. Intended Learning Outcomes of Course (ILOs) a- Knowledge and Understanding: By the end of the course, the students should be able to: a1- Understand the ultimate goals of drug product quality control / quality assurance

(QC / QA) program. a2- Know the sources of quality specifications of drugs and dosage forms.

a3- Identify the chemical purity of medicinal agents and setting of LT for possible contaminants. a4- Recognize classical & Instrumental methods cited in drug compendia. a5- Understand the validation of analytical methods. a6- Understand the stability of drugs and development of Stability Indicating Assay Methods (SIAMs). b-Intellectual Skills

By the end of this course, the student should be able to: b1- Propose suitable methods of analysis of drugs as raw material or in dosage forms or in biological fluids. b2- Distinguish the c- Professional and Practical Skills:

By the end of the course, the student should be able to: c1- Practice different analytical classical & instrumental methods of analysis.

c2- Apply the methods of validation scheme. c3- Practice suitable methods for stability studies (SIAMs).


By the end of the course, the student should be able to: d1- Practice independently in different quality control labs. d2- Evaluate and make decision to deal with different problems concerning the topics of the

course in a systematic way.



3

3. Contents

Practical number

Lecture number

Topic

1 1 - General Introductory background on (QC/QA) concepts

4 1 - Sources of quality specifications Of drugs.

- Ultimate goals of QC / QA 1 1 - Chemical purity of medicinal agents.

Sources of impurities and how to set limits for their presence.

1 2 - Classical method of Analysis as cited by different drug compendia. - Gravimetry. - Fundamentals of titrimetry.

- Application of titrimetry Including acid-base, precipitate-formation, complex- formation, & redoximetry......etc

2 Midterm Exam

1 3 - Instrumental methods of Analysis as cited by different Drug compendia.

- Spectrochemical methods. 1- UV / VIS Specrometry. 2- IR Spectrometry.& NIR Spectrometry 3- NMR Spectrometry. 4- Spctrofluorimetry. 5- AES & AAS

1 1 - Electrochemical methods: 1- Potentiometry. & ISEs 2- Polarography.

- 1 1 - Validation of analytical

Methods.

2 Stability Testing of Drugs - Chemical degradation routes - Stability Indicating Assay

Methods (SIAMs 2 2 Final Exam

-Classical method of Analysis as cited by different drug compendia.



4

- Gravimetry. - Fundamentals of titrimetry.

- Application of titrimetry Including acid-base, precipitate-formation, complex- formation, &redoximetry......etc

4.Teaching and Learning Methods 4.1- Lectures 4.2- Practical training (lab.) 4.3- Class activity. 4.4- Tutorials and Discussion.

5. Student Assessment Methods 5.1. Quiz to assess efficient study. 5.2. Written exams to assess knowledge and understanding as well as intellectual skills. 5.3. Practical exams to assess professional and practical skills. 5.4. Oral exams to assess all types of skills and mainly general and transferrable skills

Assessment Schedule Quiz ……………………………….…..Week: upon course progression Midterm…………………………………8th week Practical exam…………………………...12-13th week Final exam……………………………….14-16th week Oral exam………………………………..14-16th week

Weighting of Assessments Quiz10% Practical exam35% Midterm15% Final exam 30% Oral exam 10%

Total 100%

6. List of References

6.1- Course Book: Supplied by the Department. 6.2- Official and semi official drug compendia. 6.3- "Analytical profile of drug substances" Editor : K . florey, vol.1-vol 20, Academic press 6.4- " Analytical profiles of drug substances and excipients"

Editor.H.G. Brittain ,Vol . 21------,Academic press 6.5- " Isolation and Identification of drugs"



5

Editor: E.GC.Clarke; latest edition 6.6- Remington , The Science and Practice of Pharmacy"

Editor : Alfonso R. Gennaro, Mack Publishing Company; latest edition


7.1- Chemical reagents and indicators for proper lab work. 7.2- Analytical tools and glass wares in amount sufficient to satisfy Students need. 7.3- A reasonable number of pH- meters and UV / Vis spectrometers (student type) to improve the quality of the lab work. 7.4- An IR- spectrometer located in the central lab of the college.

Coordinator of Course:Assis. Prof.MahaAbdelmoniemHegazy


Date:1/9/2015



Pharmaceutical Analytical Chemistry Department specification analytical.pdf · highlights the basic principles underlying each experiment. Week Experiments 1 A redox ... Pharmaceutical

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