Pfizer Innovative Health - Alabama Hospital Association · 2016-10-27 · • Pfizer shares common interests with health systems via their dedication to improving healthcare and health

Confidential. Internal Use Only.

Keith Connell, Regional Business Director

Pfizer Innovative Health


Pfizer Innovative HealthPfizer Innovative Health is committed to discoverin g, developing, manufacturing, and delivering innovative products and vaccines that ch ange the outcome of chronic conditions and devastating diseases around the world. Our por tfolio helps people at every stage of life –from prevention to treatment to wellness. The pati ents always comes first.

The mission of the hospital Auxiliaries is to impro ve the health of those they serve through compassion, respect and innovation. I n order for their goal to be realized, they strive to provide high value, custom er-oriented, compassionate services to patients and other customers. In doing so, they contribute to healthier communities where each of them live.

Alabama Council of Hospital Auxiliaries


• Pfizer shares common interests with health systems via their dedication to improving healthcare and health outcomes for patients through the generation and use of objective, scientifically reliable, evidence-based research.

• Pfizer partners on quality health improvement initiatives in diabetes and chronic pain management.

• Pfizer works together with health systems to jointly develop and launch a projects of shared public interest that may positively impact healthcare for target patient populations in diabetes by using health system and Pfizer expertise and resources.

• The primary goal is to improve the health of target populations by promoting the use of evidence-based tools and research to reduce variability in care delivery, improve the overall patient experience of care and to improve the coordination of care, which may result in improved outcomes and overall lowered total costs of care.

Pfizer and Health Systems

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Diabetes and Diabetic Peripheral Neuropathy (DPN) in the United States

• Diabetes affects 29.1 million people in the US (9.3% of the population)1

– An estimated 27.8% are undiagnosed

• Diabetes is the leading cause of nontraumatic lower-limb amputations in the US2

• DPN is the most common presentation of neuropathy in diabetes3

– Decreased sensation in the feet and legs can lead to foot ulceration

– Painful DPN symptoms (burning, tingling, shooting, electric shocks) can have a profound effect on sleep, mood, ability to perform daily activities, and quality of life

~29.1 million Americans have diabetes 1

~29.1 million Americans have diabetes 1

Up to 14.6 million have DPN3

~5.8 million have pDPN 3

Up to 50% of patients with diabetes have

DPN2

~20% of patients with diabetes have

pDPN2

1. Centers for Disease Control and Prevention. National Diabetes Statistics Report: Estimates of Diabetes and Its Burden in the United States, 2014. Atlanta, GA: U.S. Department of Health and Human Services; 2014.

2. CDC. National Diabetes Fact Sheet: Atlanta, GA: Department of Human Services, Centers for Disease Control and Prevention; 2011.3. Tesfaye S, et al. Diabetes Metab Res Rev. 2012;28(suppl 1):S8-S14.


Age-Adjusted Prevalence of Diagnosed Diabetes Among US Adults: 2014 1

1. CDC National Diabetes Surveillance System. http://www.cdc.gov/diabetes/statistics/slides/maps_diabetes_trends.pptx. Accessed October 16, 2016.Age-adjusted percentage of US adults with diagnosed diabetes.

All States Median: 9.1%1. Puerto Rico 14.2%2. West Virginia 12%3. Mississippi 11.9%4. Alabama 11.8%5. Tennessee 11.7%


Relationship Between Pain Severity and Impact of pDPN on Daily Function 1

42%

26%

12%

34%

20%16%

57%

50%

28%

52%

42% 42%

82% 84%

49%

79%

70% 69%

0

10

20

30

40

50

60

70

80

90

100

Sleep Walk Drive Exercise Work Perform DailyActivities

Per

cent

“A

Lot

” or

“S

omew

hat”

Affe

cted

Mild Pain (n = 50) Moderate Pain (n = 149) Severe Pain (n = 194)

† †

†

†

† †

*

*

*

* *

1. Sadosky A, et al. Patient. 2014;7:107-114.

*P ≤ 0.05 versus mild; †P ≤ 0.05 versus mild and moderate.


Alabama Diabetic Peripheral Neuropathy Awareness Month, September 2016

ADA Standards of Medical Care 1

• All patients should be assessed annuallyfor DPN using medical history and simple clinical tests:‒ Patients with type 1 diabetes ≥5 years‒ All patients with type 2 diabetes

• Perform a comprehensive foot evaluation each year to identify risk factors for ulcers and amputations

• DPN symptoms, especially neuropathic pain, can be severe and can impact quality of life, limit mobility, and contribute to depression and social dysfunction

• Therapeutic strategies for the relief of specific symptoms related to painful DPN are recommended because they can potentially reduce pain and improve quality of life

1. American Diabetes Association. Diabetes Care. 2016;39(suppl 1):S72-S80.


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Economic Costs of Diabetes in the U.S. in 2012

1. American Diabetes Association. Diabetes Care. 2016;39(suppl 1):S72-S80.

2. Gordois A et al. Diabetes Care. 2003;26(6):1790-1795.

• Average medical expenditures for people diagnosed with diabetes is $13,700 per year, of which $7,900 is attributed to diabetes – 2.3 times higher than expenditures in

the absence of diabetes

• Care for people with diagnosed diabetes accounts for more than 1 in 5 health care dollars in the U.S. More than half is directly attributable to diabetes.

• Hospital inpatient care is the single largest contributor to the attributed medical cost of diabetes (43% of total medical cost)

• Medications represent 28% of all health expenditures attributed to diabetes

$176B

$69B

$0

$50

$100

$150

$200

Est

imat

ed C

ost o

f Dia

gnos

ed D

iabe

tes

(In

Bill

ions

of $

)

Direct Medical Costs

Reduced Productivity

Total Estimated Cost of Diagnosed Diabetes in 2012

$245 Billion

Up to 27% of the direct medical cost of diabetes may be attributed to DPN.2

Confidential. Internal Use Only. 10

Worldwide Research and Development

Pfizer Innovative Health - Alabama Hospital Association · 2016-10-27 · • Pfizer shares common interests with health systems via their dedication to improving healthcare and health

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