Management of Management of Management of Management of Hepatic Cysts Hepatic Cysts Hepatic Cysts Hepatic Cysts S bil V l MD S bil V l MD Department of Surgery Department of Surgery Sybile V al, MD Sybile V al, MD SUNY Downstate Medical Center SUNY Downstate Medical Center August 15, 2008 August 15, 2008 www.downstatesurgery.org
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Management OF hepatic cysts. Cyst aspiration is associated with high rates of recurrenceof recurrence – Surgical treatment (wide unroofing or resection) is associated with good...
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Management ofManagement ofManagement of Management of Hepatic CystsHepatic CystsHepatic CystsHepatic Cysts
S bil V l MDS bil V l MDDepartment of SurgeryDepartment of SurgerySybile Val, MDSybile Val, MD
SUNY Downstate Medical CenterSUNY Downstate Medical Center
August 15, 2008August 15, 2008
www.downstatesurgery.org
QuestionsQuestions1. Ultrasonography demonstrates a liver cyst with a thick wall
d i Th i h ld b d i dand septations. The patient should be adviseda. To have repeat sonograms every 6 months for 2 yearsb. Interventional radiologist for aspiration and biopsyc. Surgical referral for laparoscopic fenestration d. Surgical referral for complete resection
2. Cyst wall in cases of cystadenomas should bea. Partially resectedb. Completely resectedc. Suture ligatedd. Fenestrated
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QuestionsQuestions3. Sclerotherapy with alcohol leads to
a. Necrosis of cyst wallb. Fixation of the cells lining the cyst cavity thus disabling
their ability to secrete fluidc. Is never performed because it leads to cholangitisd. Has 100% success rate
4. Polycystic liver disease is a contraindication for laparoscopic fenestration
a. Trueb. Falsec. I don’t knowd. All of the above
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QuestionsQuestions5. Laparoscopic fenestration
a. Has lower recurrence rates than open unroofingb. Is considered the procedure of choice for congenital cystsc Is less morbid than traditional unroofingc. Is less morbid than traditional unroofingd. A is the only incorrect answer!
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Case PresentationCase PresentationHi tHi tHistoryHistory
• HPI: • PSH:– 56 YOF 5 week h/o
RUQ pain
PSH:– TAH/BSO– Cyst aspiration
• PMH:
y p
• Meds:• PMH:– HTN– Endometrial cancer
– Hyzaar
– No allergies
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Case PresentationCase PresentationImagingImagingImagingImaging
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Case PresentationCase PresentationI iI iImagingImaging
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Case PresentationCase PresentationPh i l E & L bPh i l E & L b
• ConclusionsConclusions– Laparoscopic technique was associated with
a reduced morbidity (25%) and shortera reduced morbidity (25%) and shorter hospital stay (3 days) compared with open deroofing (36% and 8 days)g ( y )
– With respect to recurrence, radical deroofing is key
Martin / Annals of Surgery 1998 Vol 228 167-172
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Well, what about the long termWell, what about the long term results?
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Long term resultsLong term results
• Retrospective review over 15 yearsRetrospective review over 15 years• Total of 78 patients
57 h d i l t– 57 had simple cysts– 8 hydatid cysts– 8 hepatobiliary cystadenomas– 1 hepatobilary cystadenocarcinoma
Regev et al Large cystic lesions of the liver in adults: A 15 year experience in a tertiary center Journal of American College of Surgery, 2001 Vol 193 36-45
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Long term resultsLong term results
• Retrospective review over 15 yearsRetrospective review over 15 years• 57 had simple cysts
88% f d b/ i– 88% referred b/c pain– 96.5% had normal hepatic biochemical profile
%– 49% underwent perc aspiration– 84% (48) managed surgically
• 30 laparotomy• 18 laparoscopically
Regev et al Large cystic lesions of the liver in adults: A 15 year experience in a tertiary center Journal of American College of Surgery, 2001 Vol 193 36-45
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Long term resultsLong term results
• Results:Results:– Recurrence seen in all pts s/p aspiration
No operative deaths or major complications– No operative deaths or major complications– 2 pts continued to have pain post operatively
12 5% (6/48) demonstrated recurrence– 12.5% (6/48) demonstrated recurrence• 2/18 in laparoscopic group• 4/30 in open group• 4/30 in open group
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Long term resultsLong term results
• Concluded:Concluded:– Cyst aspiration is associated with high rates
of recurrenceof recurrence– Surgical treatment (wide unroofing or
resection) is associated with good outcomesresection) is associated with good outcomes– Laparoscopic unroofing has become the
procedure of choice for large simple cysts and p g p yis associated with low complication and recurrence rates
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Location of cyst is a key factorLocation of cyst is a key factor influencing surgical outcome
Bia et al / Hepatobiliary Pancreatic Dis Int 2007
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Adjuncts to lap fenestration?Adjuncts to lap fenestration?
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The role of laparoscopic ultrasound in the minimally invasive management of a y as e a age e t o
symptomatic hepatic cysts
Schachter et al / Surg Endosc 2001 15; 364-367
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The role of laparoscopic ultrasound in the minimally invasive management of a y as e a age e t o
symptomatic hepatic cysts
Ad t f l i lt d• Advantages of laparoscopic ultrasound– Allows the precise definition of the structure of the
irregularities and solid papillary growths– Allows for US guided biopsies intraoperatively– Allow differentiation between the portal and venous
structures and the cystic lesionsstructures and the cystic lesions
Schachter et al / Surg Endosc 2001 15; 364-367
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ConclusionConclusionManagement of liver cysts should be individualized by cyst type, symptoms and associated complications
Percutaneous aspiration/ablation therapy may be a feasible option in i l did tpoor surgical candidates
Laparoscopic approaches have proven efficacious for simple cysts and are the treatment modality of choiceand are the treatment modality of choice
Management of specific diseases such as PCLD is more complicated and dictates treatment in centers with hepatobiliary and p ytransplantation expertise
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QuestionsQuestions1. Ultrasonography demonstrates a liver cyst with a thick wall
d i Th i h ld b d i dand septations. The patient should be adviseda. To have repeat sonograms every 6 months for 2 yearsb. Interventional radiologist for aspiration and biopsyc. Surgical referral for laparoscopic fenestration d. Surgical referral for complete resection
2. Cyst wall in cases of cystadenomas should bea. Partially resectedb. Completely resectedc. Suture ligatedd. Fenestrated
www.downstatesurgery.org
QuestionsQuestions3. Sclerotherapy with alcohol leads to
a. Necrosis of cyst wallb. Fixation of the cells lining the cyst cavity thus disabling
their ability to secrete fluidc. Is never performed because it leads to cholangitisd. Has 100% success rate
4. Polycystic liver disease is a contraindication for laparoscopic fenestration
a. Trueb. Falsec. I don’t knowd. All of the above
www.downstatesurgery.org
QuestionsQuestions5. Laparoscopic fenestration
a. Has lower recurrence rates than open unroofingb. Is considered the procedure of choice for congenital cystsc Is less morbid than traditional unroofingc. Is less morbid than traditional unroofingd. A is the only incorrect answer!
www.downstatesurgery.org
The End
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ReferencesReferences1. P. Schachter et al “The role of laparoscopic ultrasound in the minimally p p y
2. A. Regev et al “Large cystic lesions of the liver in adults: A 15 year experience in a tertiary center” J Am Coll Surg 193:36 45 2001experience in a tertiary center J Am Coll Surg 193:36-45, 2001
3. J.F. Gigot wt al “The surgical management of congenital liver cysts” Surgical Endoscopy 15: 357-363, 2001
4 MF H t l “M t d l t f ll f h ti4. MF Hansman et al “Management and long term follow up of hepatic cysts” The American Journal of Surgery 181; 404-410, 2001
5. I. Martin et al “Tailoring the Management of nonparasitic liver cysts” Annals of surgey 228; 167-172 1998Annals of surgey 228; 167 172, 1998
6. M. Morino et al “Laparoscopic management of symptomatic nonparasitic cysts of the liver” Annals of Surgery 219, 157-164, 1994