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Paul K. Shitabata, M.D. Dermatopathology Institute
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Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing

Sep 04, 2019

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Page 1: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing

Paul K. Shitabata, M.D.Dermatopathology Institute

Page 2: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 3: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 4: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 5: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 6: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 7: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing

Basal Cell Carcinoma, Sclerosing Type

Page 8: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing

Pearls Nests of basaloid cells

merging with angular spiky nests

Desmoplastic or scar-like stroma

Page 9: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 10: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 11: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 12: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 13: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 14: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing

Melanocytic Nevus, Intradermal Type

Page 15: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing

Pearls Nests of bland

melanocytes localized to dermis

Maturation, good peripheral circumscription, no cytologic atypia, no mitotic figures in deeper melanocytes

Page 16: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 17: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 18: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 19: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 20: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing

Seborrheic Keratosis

Page 21: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing

Pearls Flattened and fused rete

ridges

Epidermal hyperplasia

Horn pseudocysts

Page 22: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 23: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 24: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 25: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 26: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing

Basal Cell Carcinoma, Superficial Multifocal Type

Page 27: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing

Pearls Basaloid nests attached

to undersurface of epidermis

Look for peripheral palisading

Look for stroma-tumor clefting

Page 28: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 29: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 30: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 31: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 32: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing
Page 33: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing

Compound Melanocytic Nevus

Page 34: Paul K. Shitabata, M.D. Dermatopathology Institutedermpathmd.com/cases/dermatopathology_general/Dermatopathology Slide... · Dermatopathology Institute. Basal Cell Carcinoma, Sclerosing

Pearls May be dome shaped,

symmetrical

Junctional melanocytesmerging with dermal melanocytes

Good maturation with no cytologic atypia or deep mitotic figures