Patologie reumatiche Francesca Galeazzi UOC Gastroenterologia Azienda Ospedale-Università Padova Joint Meeting GISMAD-AIGO-SIED-SIGE DISTURBI DELLA MOTILITA’ GI NELLE PATOLOGIE SISTEMICHE XVI Congresso della Federazione Nazionale delle Malattie Digestive (FISMAD) Verona, 6-9 Marzo 2010
XVI Congresso della Federazione Nazionale delle Malattie Digestive (FISMAD) Verona, 6-9 Marzo 2010. Joint Meeting GISMAD-AIGO-SIED-SIGE DISTURBI DELLA MOTILITA ’ GI NELLE PATOLOGIE SISTEMICHE. Patologie reumatiche. Francesca Galeazzi UOC Gastroenterologia - PowerPoint PPT Presentation
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SSc Wegener Sjogren Beçhet RA LES Poli/Derma Mixed
%
0
Sjogren
27 pts -dysphagia 76% (40.6% severe)
Xerostomia?
•Simultaneous contractions distal (22%) and proximal (11%) esophagus
•No relation with salivary function
Anselmino M et al, Dig Dis Sci 1997
Sal
ivar
y o
utf
low
(g
r/2
min
)
Fibromyalgia
Chronic musculo-skelatal pain without tissue inflammation or damage
Fibromyalgia
IBS
Irritable bladder
FD
TMD Intestinal permeability
Stressors
Pain processing
Pamuk ON et al, J Rheumatology 2009
Fibromyalgia
Pamuk ON et al, J Rheumatology 2009
GI motility and
Rheumatic diseases GI motility alterations commonly described in rheumatic
diseases, affecting > 90% pts in SSc
Except for SSc, specific pattern of motor abnormalities unclear
In SSc GI motility impairment may represent the most relevant internal manifestation, with potentially severe complications
Difficult to identify patients and to predict severity of motor alterations only on the basis of clinical symptoms and in absence of specific “markers” (subgroups of patients?)