PATIENT WITH IDIOPATHIC THROMBOCYTOPENIA PURPURA A Case Study Presented to The Clinical Instructors AUP College of Nursing Silang, Cavite In Partial Fulfillment Of the Requirements in Maternal & Child Health Nursing Care Management Presented By: Jabat, Sienna Adante, Lindy Sales, Raymond Tuazon, Stephen
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
PATIENT WITH IDIOPATHIC THROMBOCYTOPENIA PURPURA
A Case Study
Presented to
The Clinical Instructors
AUP College of Nursing
Silang, Cavite
In Partial Fulfillment
Of the Requirements in
Maternal & Child Health Nursing Care Management
Presented By:
Jabat, Sienna
Adante, Lindy
Sales, Raymond
Tuazon, Stephen
March 13, 2011
CHAPTER I
INTRODUCTION
Idiopathic thrombocytopenic purpura is a blood disorder characterized by an abnormal
decrease in the number of platelets in the blood. Platelets are cells in the blood that help stop
bleeding. A decrease in platelets can result in easy bruising, bleeding gums, and internal
bleeding. ITP is a disease that affects all ages, but is more common among children and young
women.
There are 2 forms of ITP: acute and chronic. The acute form, which is normally found in
children, is a disease that is self-limiting usually following a viral infection of 1-6 weeks. This is
most commonly seen in young children (2 to 6 years old). The symptoms may follow a viral
illness, such as chickenpox. Acute ITP usually has a very sudden onset and the symptoms
usually disappear in less than six months (often within a few weeks). The disorder usually does
not recur. Acute ITP is the most common form of the disorder. In the chronic form, the onset of
the disorder can happen at any age, and the symptoms can last a minimum of six months or
several years. Adults have this form more often than children, but it does affect adolescents.
Females have it two to three times more often than males. Chronic ITP can recur often and
requires continual follow up care with a blood specialist (hematologist).
Idiopathic- means the cause is unknown.
Thrombocytopenia- means a decreased number of platelets in the blood.
Purpura- refers to the purple discoloring of the skin, as with a bruise.
Significance of the Study
As will be made evident in the follow presentation of research, ITP is becoming more and
more of a problem as prevalence rates increase. In the United States alone, it affects
approximately four to eight per 100,000 children under the age of 15 each year. The purpose of
performing this study is to provide knowledge to all those present with vital information that will
aid them in handling future cases and incidences relating to the topic.
As students and professional healthcare providers, we have the responsibility to care for
our patients affected by this disease as well as others. By obtaining knowledge and proper
understanding of the disease and how it works, ITP’s progression and prevalence can be
monitored, controlled, and ultimately stopped.
Objectives of the Study
At the end of this case presentation, students will be able to:
1) Define Idiopathic Thrombocytopenic Purpura
2) Identify risk factors associated with the disease
3) List signs and symptoms related to ITP
4) Know what body systems ITP affects and how
5) Understand the pathophysiology and disease process
6) Apply proper management in caring for patients with ITP
7) Formulate appropriate nursing care plans for patients with ITP
CHAPTER II
PATIENT DATABASE
Demographic Data:
Baby Ayesha E. Tompong was delivered via normal spontaneous delivery by her mother
Evalyn Tompong at Calamba Medical Center with the service of Dr. Fonte Delmundo on July
31, 2010. Ayesha currently resides at BLK 71 Lot 10 Phase 2 Asia 2 Kapayapaan Ville,
Canlubang, Calamba City, Laguna. Ayesha was admitted in the Pediatric Department of
Calamba Medical Center on November 16, 2010 with a chief complaint of rashes and epistaxis.
She was diagnosed with Idiopathic Thrombocytopenic Purpura.
Developmental Tasks:
a) Erik Erikson (Psychosocial Development)
Stage: Infancy
Age:Birth-18 months
Central task: Trust versus Mistrust
Developmental task: Learn to build trust with others. This is so important because the
baby needs to feel attention in order to develop security within environment.
Whenever the baby cry the mother gives her a comfort we can see that the child has a
trust to her mother, that every time I check her V/S the child cries so the part of the
mother is to give her a comfort so the baby builds a trust.
b) Sigmund Freud (Psychosocial Development)
Stage: Oral
Age: birth to 1 ½ years
Developmental task: Mouth is the center of pleasure (major source of gratification and
exploration), security is primary need, Major conflict: weaning.
The main focus of this task is to make feeding a pleasurable experience giving the child a
sense of comfort and security. This is met by the mother breastfeeding the baby to initiate
satisfaction of baby’s needs.
Health History
a) Family History
- (+) hypertension on father’s side
- (+) asthma on mother’s side
b) Past Medical History
-NSD
-cough and colds 6 days prior to admission
-a fever 3 days prior to admission
c) History of Present Illness
Six days prior to admission the mother brought baby Ayesha to the local health center to
have her DPT vaccination. The mother verbalized that the procedure that they used was
improper, because the equipment was not cleaned properly. Also, alcohol was not used to
disinfect the injection site. After two days, the baby had a high fever with a temperature of 38
Celsius. The mother also noticed blood coming from Ayesha’s nose and rashes all over the body.
She was brought to Calamba Medical Center for treatment.
Nursing Assessment
Assessment for Idiopathic Thrombocytopenic Purpura
Normal Findings Book Picture Actual signs and symptoms of Patient
INTEGUMENTARY
Even in color Hair Distribution
even Warm to touch Good Skin turgor No lesions, lumps
or masses Firm nails Acynotic nail beds Good capillary refill
(<3 sec)
Pallor/ Jaundiced of mucous membranes
Pallor/Cyanotic nail beds
Pallor of gums, conjunctiva and palmar creases
Petechiae, purpura, and large bruises
Cool to touch Nails become
brittle and may lose the normal convex shape; over time, nails become concave and fingers assume clublike appearance.
Poor capillary refill time
General Pallor Pale palpebral conjunctiva Warm to touch (+) Petechiae (+) Purpura (-) Bruises
1. Monitored platelets daily. Risk of bleeding increases as platelet count drops:
<20,000/mm3 = severe risk
20,000 to 50,000/mm3= moderate risk; may note prolonged bleeding at invasive sites
50,000 to 100,000/ mm3= mild risk; does not usually require treatment.
>100,000/mm3= No significant risk.
2. Monitored coagulation parameters (fibrinogen, thrombin time, bleeding time, fibrin degradation products) if indicated. Changes in
coagulation profile maybe marked by ecchymosis, hematomas, petechiae, blood in body excretions, bleeding from body orifices, and change in
neurological status.
3. Inspected patient irregularly for evidence of the following:
Spontaneous petechiae (all skin surfaces, including oral mucosa)
If any significant bleeding occurs, monitored vital signs closely until bleeding is controlled.
Early assessment facilitates prompt treatment and reduced risk for complications. Patient safety is priority.
Dependent:
1. Administered IVIg. Immunoglobulins are proteins manufactured in the body that the immune system uses to produce antibodies and various
factors, which are used to communicate with immune system cells and modify the immune reaction.
Evaluation
Short term:
Goal met. After 8 hours of nursing intervention the patient manifested no signs of active bleeding.
Long term.
Goal met. After 3-5 days of nursing intervention the patient’s platelet count will returned to within the normal range of 150-400 k
PROBLEM #4: Rashes
Cues:
Subjective:
“Napansin kong may rashes ang kamay ng anak ko.” Mother stated
Objective
-Rashes
-Disruption of skin surface (epidermis)
-Poor capillary refill (4-5 sec)
Nursing Diagnosis:
Impaired skin integrity related to altered immune system as manifested by rashes
Altered epidermis due to bleeding and tiny purple spot on the skin
Planning
NOC: Skin and mucous membrane
Short term:
After 8 hours of nursing intervention the patient will be able to manifest decreased rashes, redness on the skin
Long term:
After 2 weeks of nursing intervention the patient will be able to improved or have good capillary refill and regain skin integrity such as remove
the rashes
NIC: Infection Protection
Independent:
1. Assess the history of condition, including age at onset, date of first episode, original site, characteristic of skin, and any changes that
have occurred. Redness, swelling, pain, itching are signs of the body’s immune response to localized tissue trauma.
2.Maintain proper environmental conditions, including room temperature and ventilation. To provide evidence of the effective of skin
regimen.
3. Maintain proper environmental conditions, including room temperature and ventilation. -Providing comfortable environment.
Dependent:
Evaluation:
Short term
Goal met. After 8 hours nursing intervention the patient manifested decreased rashes and redness on the skin
Long term
Goal met. After 2 weeks of nursing intervention the patient’s rashes all over the body will gone.
PROBLEM #5: Difficulty of breathing
Cues:
Subjective:
“Nahihirapan ang anak kong huminga”, as verbalized by the mother.
Objective:
-RR: 65 bpm (November 16, 2010)
-Seen patient’s lying in bed asleep.
-Pallor of skin and mucous membrane
- Bluish discoloration on left and right upper arms
-difficulty of breathing at rest noted.
Nursing Diagnosis:
Impaired gas exchanged related to decreased oxygen carrying capacity of blood due to bleeding.
A changed in patient’s respiratory rate or pattern maybe one of the earliest indication of the need of oxygen therapy. The change in respiratory rate may result from hypoxymia which is a decreased in arterial tension in the blood manifested by difficulty of breathing.
Planning
NOC: Respiratory status gas exchange
Short term:
After 5 minutes of nursing intervention the client will be able demonstrate the improve ventilation /oxygenation .
Long Term:
After the end of the shift of nursing intervention the patient will be able to have good airway clearance.
Nursing Intervention:
NIC: Respiratory monitoring: oxygen therapy
Independent:
1.Assess patient’s V/S and evaluate for any adverse effect of CO2 toxicity (such as difficulty of breathing). Excessive CO2 blood level may cause respiratory obstruction
2 . Promote frequent position such us sitting and deep breathing exercised. Promote lung expansion.
3. Provide fluid with electrolytes provide supplemental fluid and calories. To prevent dehydration.
Dependent:
1. Adjust O2 level if patient’s shows adverse effect as indicated. ( Oxygen as ordered).Complication usually from prolong O2 therapy.
Evaluation:
Short term:
Goal met. After 5 minutes of nursing intervention the client demonstrated the improve ventilation /oxygenation
Long term:
After 8 hours of nursing intervention the patient have good airway clearance.
PROBLEM #6: Pallor
Cues:
Subjective:
SUBJECTIVE:
“Napansin kong maputla ang anak ko at medyo mabilis din ang paghinga .” Mother stated.
OBJECTIVE:
-pale skin
-thready pulse
-Poor capillary refill 4-5 sec.
-restlessness
-hemoglobin of 102 (Normal value: 130-180 gm/L)
Nursing Diagnosis
Ineffective tissue perfusion related to decreased circulating blood volume due to bleeding
Decrease in oxygen resulting in the failure to nourish the tissues at the capillary level. Tissue perfusion problems can exist without decreased cardiac output; however there may be a relationship between cardiac output and tissue perfusion.
NOC:Tissue perfusion: cardiac
Short term:
After 30 minutes of nursing intervention the patient will be able to improved tissue perfusion
Long term:
After 1 day of nursing intervention the patient will be able to maintain vital signs and increase tissue perfusion
Nursing Intervention:
NIC: Circulatory care
Independent:
1. Assess skin for coolness, pallor, cyanosis, diaphoresis, delayed capillary refill. Changes may reflect diminished circulation/hypoxia potentiating capillary occlusion.
2. Monitor vital signs carefully. Assess pulse for rate, rhythm, and volume. Note hypertension; rapid, weak, thread pulse; and increased/shallow respirations. Sludging and sickling in peripheral vessels may lead to complete or partial obliteration of a vessel with diminished perfusion to surrounding tissues.
3. Maintain adequate fluid intake. Monitor urine output. Dehydration not only causes hypovolemic but increases sickling and occlusion of capillaries. Decreased renal perfusion/failure may occur because of vascular occlusion.
4. Maintain environment temperature and body warmth without overheating. Prevent vasoconstriction; aids in maintaining circulation and perfusion. Excessive body heat may cause diaphoresis, and adding to insensible fluid losses and risk for dehydration.
Collaborative:
1.Assist with treatment of underlying condition such as medications, fluid replacement/rehydration , as indicated. To improve tissue perfusion/organ function.
Evaluation:
Short term:
Goal met.
After 30 minutes of nursing intervention the patient manifested good tissue perfusion with pinkish color.
Long term:
Goal met.
After 1 day of nursing intervention the patient improved tissue perfusion as evidence by stabilized vital signs, adequate intake/ output, normal capillary refill.
CHAPTER VI
THE MANAGEMENT
DIAGNOSTIC TEST:
1. Complete Blood Count (CBC)
Type of Test: Blood
Body System and Functions: Hematological System
Normal Findings:
Hematocrit:
Male 41.5%-50.4%
Female 35.9%-44.6%
Hemoglobin:
Male 14.0-17.5 g/dL
Female 12.3-15.3 g/dL
Red Cell Count 4.7-6.1 M/mL
White Cell Count 4.8-10.8 K/mL
Platelet Count 150-400 K/mL
Neutrophils 35%-70%
Lymphocytes 25%-45%
Monocytes 0%-12%
Eosinophils 0%-7%
Basophils 0%-2%
Test Description: The CBC is a combination report of a series of tests of the peripheral blood.
The quantity, percentage, variety, concentrations, and quality of blood cells are identified. The
tests usually included in a CBC are hematocrit, hemoglobin, red cell count, red blood cells
indices, white cell count, and differential white blood cells count. Red blood cell indices consist
of the following tests: stained red cell examination, and platelet count. The differential white
blood cell count consists of neutrophils, eosinophils, basophils, lymphocytes, and monocytes.
November 20, 2010
Blood Component Normal Value (CMC) Patient’s ResultRBC (3.9-5.2 x 10^6/uL) 3.5Hematocrit (0.40-0.54) 0.30Hemoglobin (130-180 gm/L) 102WBC 4.5-11 X 10^9/L 4.5Bleeding Time 1-3 min 1Clotting Time 2-5 minPlatelets 130-400 x 10^3 Ul 120
2. Immune Globulin for I.V.- IV Route only
Immunoglobulins are proteins manufactured in the body that the immune system uses to
produce antibodies and various factors, which are used to communicate with immune system
cells and modify the immune reaction. There are 4 immunoglobulin subtypes, immunoglobulin
M (IgM), immunoglobulin A (IgA), immunoglobulin G (IgG or gamma globulin) and
immunoglobulin E (IgE). IgG are the basic component used in the manufacture of long-acting
antibodies. Immune globulin products derived from human plasma were first used in 1952 to
treat patients with conditions of immune deficiency and chronic lymphocytic leukemia. These
first immune globulin transfusions were administered intramuscularly. In the early 1980s
intravenous preparations of immune globulin (IVIG) were first used to treat patients with
idiopathic thrombocytopenic purpura, an autoimmune condition causing platelet deficiencies.
IVIG is used in many different autoimmune disorders, and most IVIG is produced from
pooled human plasma derived from multiple blood donors. IVIG typically contains more than 95
percent unmodified IgG with intact immune signaling functions along with trace amounts of IgA
and IgM, cytokines, soluble complement, and HLA molecules. IVIG is an immunomodulator
in that it balances the immune system, strengthening immune systems that are too weak
and reducing activity in overactive immune systems. IVIG also contains anti-idiotypes that
neutralize various autoantibodies.
3. Paracetamol- 100mg/ml, 0.5 drops, P.O, PRN
Direct action unclear. Pain relief may result from inhibition of prostaglandin synthesis in
CNS, with subsequent blockage of pain impulses. Fever reduction may result from vasodilation
and increased peripheral blood flow in hypothalamus, which dissipates heat and lowers body
temperature.
The preparation is indicated in diseases manifesting with pain and fever: headache,
toothache, mild and moderate postoperative and injury pain, high temperature, infectious
diseases and chills
4. Solucortef- 20mg, IV
Solu-Cortef is a corticosteroid. Corticosteroids are hormones produced naturally by the
adrenal glands which have many important functions on every organ system. Corticosteroids
affect the heart and its response to natural chemicals that affect heart rate. They also affect water
and salt balance in the body and allow the body to cope with stress. They do so by increasing the
rate and force of the heartbeat, increasing blood supply to essential areas, such as the heart, brain
and muscles, and increasing the body’s supply of energy by raising blood sugar levels. Solu-
Cortef is also used to control symptoms caused by sudden low levels of corticosteroids in the
body. This can be due to many reasons, including abnormal stress in disorders such as Addison’s
disease, or surgical removal of the adrenal glands. Low blood levels of corticosteroids must be
treated with replacement therapy to ensure the body functions normally. Solu-Cortef is also
used to treat inflammation, and does so by acting within cells to prevent the release of
certain chemicals tat are important in the immune system. These chemicals are normally
involved in producing immune and allergic responses, resulting in inflammation. Decreasing the
release of these chemicals in a particular area reduces inflammation.
5. Comprilex- 1mL, P.O, OD
Comprilex kills actively growing tubercle bacilli by inhibiting the biosynthesis of
mycolic acids which are the major components of the bacterial cell wall of Mycobacterium
tuberculosis. Pyridoxine hydrochloride: Pyridoxine hydrochloride is converted to its active
forms, pyridoxal phosphate and pyridoxamine phosphate, required in the metabolism of proteins,
carbohydrates and fats. It enables body tissues to obtain energy from metabolism to
carbohydrates, fats, and proteins by functioning as coenzymes for various metabolic and
biochemical reactions.
GENERAL EVALUATION OF THE STUDY
A. Implication of the study to:
1.Nursing Education
Nursing education is the furtherment and complete utilization of resources to equip one’s
self with the knowledge and skills necessary to enable him/her to perform at maximum capacity
not only as a nurse in the workplace, but as a certified healthcare provider where ever the calling
may be. We as nurses must be educated in order to apply ourselves within our scope of practice.
2. Nursing Practice
Upon availing of proper education, we must then begin to practice what was taught to us
in order to fulfill that which is expected of us. The field in which we work is full of unexpected
twists and turns and we must be ready to face these head on. Our goal in this chosen career is to
practice the unique set of skills given to us by our mentors to gradually build confidence and
maturity so that we as professionals may be able to restore, promote, and maintain the good
health of those under our care.
3. Nursing Research
There is a continual desire to strive in improving the status and prestige that is our
profession. As the years go by, technology is furthering its grasp challenging our very foundation
of reality. We must continue to update ourselves with the new and upcoming trends, studies, and
research that are being incorporated each and every day. In order for us to meet the demand, we
must fervently yet patiently strive to stay informed, and by doing such, we as nurses can provide
the best care for our patients.
B. Summary and Conclusion:
Hematologic diseases are complex disorders that require the nurse to understand the
hematopoietic system. The nurse is often involved in the administration of blood and blood
products for treatment of these various disorders. Many of the blood disorders are life-
threatening; others are easily controlled with proper nutrition or regular medication.
Because blood and blood product transfusions are widely used in the treatment of
hematologic disorders, it is vital that you understand this procedure, the implications of these
procedures, and the proper techniques of administration so the client will receive safe and
effective care.
Idiopathic Thrombocytopenic Purpura is a blood disorder characterized by an abnormal
decrease in the number of platelets in the blood. Knowledge of the interaction of the genetic
profile coupled with a person's lifestyle, work environment, and family context provide a more
holistic picture of a person's health profile. The clinical implications are that this knowledge will
provide opportunities for health professionals to advise families on individualized treatment
options or to tailor health promotion to future disease states based on genes and their interaction
with the environment.
Educational programs have significant positive effect on increase in knowledge of
parents about the disease. No significant differences were found between the three groups tested
in terms of the mean age, gender, level of education, job, number of affected children, and age of
the child. However young parents were better educated as regards knowledge about blood
disorders such as Idiopathic Thrombocytopenic Purpura.
My patient has a good prognosis if she continues to adhere to the medical advices her
physician ordered. Continues transfusion of platelets and IgG can do so much for my patient,
combined with proper nutrition and adherence to her medications.
CHAPTER VII
REFERENCES
Book Sources
1. Kozier & Erb’s Fundametals of Nursing 8th edition
2. Fogarty PF, Segal JB. The Epidemiology of Immune Thrombocytopenic Purpura. Curr Opin Hematol.2007