Pathways Database System: An Integrated System For Biological Pathways L. Krishnamurthy, J. Nadeau, G. Ozsoyoglu, M. Ozsoyoglu, G. Schaeffer, M. Tasan and W. Xu Bioinformatics Vol. 19 no. 8 2003. Pages 930-937 Presented by Mohamed Uduman Bioinformatics Computing II Spring 043
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Pathways Database System: An Integrated System For Biological Pathways L. Krishnamurthy, J. Nadeau, G. Ozsoyoglu, M. Ozsoyoglu, G. Schaeffer, M. Tasan.
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Pathways Database System: An Integrated System For Biological Pathways
L. Krishnamurthy, J. Nadeau, G. Ozsoyoglu, M. Ozsoyoglu, G. Schaeffer, M. Tasan and W. XuBioinformatics Vol. 19 no. 8 2003. Pages 930-937
Presented by
Mohamed Uduman
Bioinformatics Computing II
Spring 043
Outline
Background Pathways Database System Architecture of the system Data model Tools of the Pathways Database System Other pathway tools Future Developments Conclusion Questions
Background
Genome sequencing – what to do with data? DNA sequence good for analyzing
Organization Evolution Mutation
Biological Pathways “Pathways are the sequential and cumulative action
of genetically distinct but functionally related molecules.”
Background
Biological Pathways Metabolic & biochemical
Transcription & protein synthesis
Signal Transduction
Pathways Database System
Genomic pathway information: Store / manage Analyze Visualize Query
Features GUI tools Multiple abstraction levels for viewing information XML output