Parallel and Simultaneous Dispensing of Nanoliter Volumes for the Production of BioChips and Diagnostic Tests Bellows Dispensing Technolog
Parallel and Simultaneous Dispensing of Nanoliter Volumes for the Production of BioChips and Diagnostic Tests Bellows Dispensing Technology.
Dec 17, 2015
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Parallel and Simultaneous Dispensing of Nanoliter
Volumes for the Production of BioChips and Diagnostic
Tests
Bellows Dispensing Technology
Bottom valves are opened
Dispenser is ready for dispensing
Top valves are closed
Bellows are filled and expanded
Connections to individual reagent reservoirs
Bottom valves
Top valves
Bellows
Dispenser needles
bottom valves opened
Lilliput Plate is positioned
top valves are closed
Bellows are filled and expanded
Connections to individual reagent reservoirs
bottom valves opened
Dispensing starts
top valves are closed
mechanical compressionof the bellows
Connections to individual reagent reservoirs
bottom valves opened
trackdown of the Lilliput chip
Connections to individual reagent reservoirs Dispensing ready
top valves are closed
mechanical compressionof the bellows
bottom valves opened
Removal of theLilliput chip
top valves are closed
mechanical compressionof the bellows
removal of the Lilliput chip
Connections to individual reagent reservoirs
Valve operation
top valves are closed
Connections to individual reagent reservoirs
bottom valves are closing
bottom valves are closing
Valve operation
top valves are closed
Connections to individual reagent reservoirs
bottom valves are closing
Valve operation
top valves are closed
Connections to individual reagent reservoirs
bottom valves are closing
Valve operation
top valves are closed
Connections to individual reagent reservoirs
bottom valves closed
Valve operation
top valves are opening
Connections to individual reagent reservoirs
bottom valves closed
Valve operation
top valves are opening
Connections to individual reagent reservoirs
bottom valves closed
Valve operation
top valves are opening
Connections to individual reagent reservoirs
bottom valves closed
Bellows ready for refill
top valves are open
Connections to individual reagent reservoirs
bottom valves closed
Bellows ready for refill
top valves opened
Connections to individual reagent reservoirs
bottom valves closed
Bellows refill
top valves opened
Connections to individual reagent reservoirs
Bellows expand
bottom valves closed
Bellows refill
top valves opened
Connections to individual reagent reservoirs
Bellows expand
bottom valves closed
Bellows refill
top valves opened
Connections to individual reagent reservoirs
Bellows expand
bottom valves closed
Bellows refill
top valves opened
Connections to individual reagent reservoirs
Bellows expand
bottom valves closed
Bellows refill
top valves opened
Connections to individual reagent reservoirs
Bellows expand
bottom valves closed
Bellows refill
top valves opened
Connections to individual reagent reservoirs
Bellows expand
bottom valves closed
Bellows refill
top valves opened
Connections to individual reagent reservoirs
Bellows expand
top valves are closing
bottom valves areopening
Valve operation Connections to individual reagent reservoirs
Valve operation Connections to individual reagent reservoirs
top valves are closing
bottom valves areopening
bottom valves opened
Dispenser ready for operation
top valves closed
Connections to individual reagent reservoirs
SpecificationsSpecifications
Accuracy: VC < 2%
Volumes: 200nl up to 2000nl [2µl – 100µl]
Bellows size: 3µl up to 2ml
Channels: 1 to 384 in parallel
Reagents: 1 to 192 different solutions simultaneously
Operation Modes: - constant dispensing from reservoirs- aspirate and dispense
Outlet: - stainless steel needles (teflon or paralene coated)- pipette tips
Movement Control: Stepper motor. Resolution 14,9 steps to squeeze 1 nl
References: - manufacturing of 384 well plates - manufacturing of Lilliput Chip- manufacturing of 96 well Micro Titer Plates
Accuracy: VC < 2%
Volumes: 200nl up to 2000nl [2µl – 100µl]
Bellows size: 3µl up to 2ml
Channels: 1 to 384 in parallel
Reagents: 1 to 192 different solutions simultaneously
Operation Modes: - constant dispensing from reservoirs- aspirate and dispense
Outlet: - stainless steel needles (teflon or paralene coated)- pipette tips
Movement Control: Stepper motor. Resolution 14,9 steps to squeeze 1 nl
References: - manufacturing of 384 well plates - manufacturing of Lilliput Chip- manufacturing of 96 well Micro Titer Plates
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