A Guide toTitration of OryContin@ Adequare retier in r-t-M-E 10 mq Tablets CSr ffirU b58&. t raaat-t 0xy0onlin. q12h 0ose tt**tw Mundipharma Pharmaceuticals Sdn Bhd 74, Jalan University, 46200 Petaling Jaya, Selangor, Malaysia Tel : (603) 7966 0730 Fax : (603) 7957 9909 Mundipharma Pharmaceuticals Pte Lld .l Q Hoe Chiang Road, #3 2O-04l05 Keppel Towers, Singapore 08931 5 Tel : (65) 6511 1165 Fax : (65) 6511 1167 T Titrate patients every 1 to 2 days, if necessary lncrease the dose of OxyOontin@ Tablets by 25Y" to 507o, if necessary (refer to the chart when titrating upward from 1Omg q12h). Do not increase the dosing frequency. Manage exacerbations of pain with immediate-release medication. Elevate the dose of OxyContin@ Tablets if more than 2 doses of immediate-release opioid medication per day are required. M E t4u/a fuo* Pa^^, E/+rr;/4<t t^lf Af-"