Overview of and Update on the Reorganization :

Overview of and Update Overview of and Update on the Reorganizationon the Reorganization : :Endocrinology, Metabolism, Nutrition, and Endocrinology, Metabolism, Nutrition, and Reproductive Sciences (EMNR) IRGReproductive Sciences (EMNR) IRG

Proposed by the Panel on Scientific Proposed by the Panel on Scientific Boundaries for ReviewBoundaries for Review

Center for Scientific Review, N I H,Center for Scientific Review, N I H,U.S. Department of Health and Human ServicesU.S. Department of Health and Human Services

Center for Scientific Center for Scientific Review Review (C S R ) (C S R )Receives, processes, and refers Receives, processes, and refers

applications submitted to NIH and applications submitted to NIH and some other DHHS agencies.some other DHHS agencies.

The primary goal is to see that NIH The primary goal is to see that NIH applications receive fair, independent, applications receive fair, independent, expert, and timely review--free from expert, and timely review--free from inappropriate influence—inappropriate influence—

so NIH can fund the most promising so NIH can fund the most promising research.research.

C S RC S R CSR reviews about 70 % of grant CSR reviews about 70 % of grant

applications submitted to NIHapplications submitted to NIH

CSR reviews most investigator CSR reviews most investigator initiated, fellowship, SBIR/STTR initiated, fellowship, SBIR/STTR applications sent to NIH from USA applications sent to NIH from USA and foreign countriesand foreign countries

(R01, R21, R15, F32, SBIR/STTR)(R01, R21, R15, F32, SBIR/STTR)

Beginnings of the Beginnings of the ReorganizationReorganization

In late 1996, Dr. Ellie Ehrenfeld came to In late 1996, Dr. Ellie Ehrenfeld came to NIH and was soon led by discussions with NIH and was soon led by discussions with scientists inside and outside of NIH to scientists inside and outside of NIH to propose a systematic reorganization of propose a systematic reorganization of CSR's study sections so they can better CSR's study sections so they can better review the increasingly complex and review the increasingly complex and diverse grant applications submitted to diverse grant applications submitted to NIH. NIH.

Panel on Scientific Boundaries for Panel on Scientific Boundaries for Review (PSBR): Phase 1Review (PSBR): Phase 1

Defined principles for organizing science Defined principles for organizing science into clusters of study sections called into clusters of study sections called Integrated Review Groups (IRGs)Integrated Review Groups (IRGs)

Recommended a set of 23 IRGs (EMNR Recommended a set of 23 IRGs (EMNR IRG was one them) Developed process for IRG was one them) Developed process for establishing study sectionsestablishing study sections

Recommended guidelines for “cultural” Recommended guidelines for “cultural” practices in study sectionspractices in study sections

Input from Research Communities – Input from Research Communities – Phase 1Phase 1 PSBR presented its draft report to CSR in May PSBR presented its draft report to CSR in May

19991999 Draft report was sent to professional societies – Draft report was sent to professional societies –

many of whom organized group responsesmany of whom organized group responses Draft report was also posted on the Web for Draft report was also posted on the Web for

individual comments (~750 received)individual comments (~750 received) All comments were consideredAll comments were considered Meetings and teleconferences were held with Meetings and teleconferences were held with

concerned communitiesconcerned communities Draft report was revised Draft report was revised Report was finalized after it was accepted by Report was finalized after it was accepted by

the CSR Advisory Committee on January 10, the CSR Advisory Committee on January 10, 20002000

Panel onPanel on Scientific Boundaries for Review Scientific Boundaries for Review

(PSBR)(PSBR)

January 2000,January 2000,

23 IRGs were outlined with the 23 IRGs were outlined with the expectation that, as much as possible, expectation that, as much as possible, new study sections would be designed new study sections would be designed to bring basic science studies closer to to bring basic science studies closer to the organ or disease that they addressthe organ or disease that they address

http://www.csr.nih.gov/Events/http://www.csr.nih.gov/Events/summary012000.htmsummary012000.htm

Panel on Scientific Boundaries for Panel on Scientific Boundaries for Review: Phase 2Review: Phase 2

Design and establish study sections Design and establish study sections for each IRGfor each IRG

Guidelines for Phase 2Guidelines for Phase 2

Seven IRGs (recently established) Seven IRGs (recently established) were exempt from reorganization were exempt from reorganization ( Neuroscience, Behavioral and social ( Neuroscience, Behavioral and social sciences, AIDS and related research)sciences, AIDS and related research)

Overlap is goodOverlap is good Though applications should, in Though applications should, in

general, be reviewed in IRGs focused general, be reviewed in IRGs focused on specific diseases or organ systems, on specific diseases or organ systems, there are cross-cutting themes that there are cross-cutting themes that should be clustered together instead should be clustered together instead of being distributed across many IRGsof being distributed across many IRGs

Preparation for Phase 2Preparation for Phase 2Mock Sort of ApplicationsMock Sort of Applications

~10,000 applications from May 2000 ~10,000 applications from May 2000 Council round were sorted into the Council round were sorted into the proposed study sectionsproposed study sections Referral staff followed PSBR guidelines Referral staff followed PSBR guidelines

and identified ambiguities and identified ambiguities Review staff reviewed the resulting sort Review staff reviewed the resulting sort

and identified overlaps, errors, and and identified overlaps, errors, and disagreementsdisagreements

A database was constructed to A database was constructed to catalog issues and concerns catalog issues and concerns

Preparation for Phase 2 (cont’d.)Preparation for Phase 2 (cont’d.)

A second mock sort was conducted A second mock sort was conducted using applications from the October using applications from the October 2002 Council round to identify new 2002 Council round to identify new trends and make appropriate course trends and make appropriate course correctionscorrections

Process for Process for Implementing Implementing Phase 2Phase 2

For each proposed IRG, CSR Division Directors For each proposed IRG, CSR Division Directors appointed Steering Committees composed of CSR appointed Steering Committees composed of CSR review and Institute program staff to-- review and Institute program staff to-- Identify all scientific communities involved in IRGIdentify all scientific communities involved in IRG Contact relevant professional societies for Contact relevant professional societies for

nominationsnominations Select and convene Study Section Boundaries Select and convene Study Section Boundaries

(SSB) Teams of experts in field plus (SSB) Teams of experts in field plus representative(s) from parent PSBRrepresentative(s) from parent PSBR

SSB Teams involving 384 external experts and 180 SSB Teams involving 384 external experts and 180 representatives from NIH Institutes and Centers representatives from NIH Institutes and Centers drafted designs for 16 IRGs based on sorted drafted designs for 16 IRGs based on sorted applications and the comments databaseapplications and the comments database

Process for Process for ImplementingImplementing Phase 2 Phase 2 (Cont’d)(Cont’d)

Proposed study sections were posted on the Web Proposed study sections were posted on the Web for broad community comment (over 1,800 for broad community comment (over 1,800 received)received)

Additional consultations and revisions were madeAdditional consultations and revisions were made When overlaps occurred, CSR solicited input from When overlaps occurred, CSR solicited input from

relevant communities to make appropriate relevant communities to make appropriate modifications and held final recommendations modifications and held final recommendations until all SSB Teams provide inputuntil all SSB Teams provide input

CSR Advisory Committee has reviewed all but two CSR Advisory Committee has reviewed all but two SSB Team proposals SSB Team proposals

Study Section boundaries will only be final once Study Section boundaries will only be final once all SSB teams have completed their deliberationsall SSB teams have completed their deliberations

CSR anticipates it will complete its CSR anticipates it will complete its reorganization in early 2005reorganization in early 2005

Current Status for EMNR IRGCurrent Status for EMNR IRG SSB Team of the EMNR IRG met in April, SSB Team of the EMNR IRG met in April,

20022002

proposed 7 study sectionsproposed 7 study sections CSR Advisory Committee has approved CSR Advisory Committee has approved

study section recommendations for study section recommendations for EMNR IRG on May 12-13, 2003 EMNR IRG on May 12-13, 2003

Implementation will be one year after Implementation will be one year after study sections established by the CSR study sections established by the CSR DirectorDirector

First meetings of components study First meetings of components study sections expected for June 2004 sections expected for June 2004 (receipt of Feb/March)(receipt of Feb/March)

(We are right on schedule)(We are right on schedule)

Study Section Boundary (SSB) Study Section Boundary (SSB) Team of EMNR proposed 7 study Team of EMNR proposed 7 study sectionssections

Molecular and Cellular Endocrinology (MCE)Molecular and Cellular Endocrinology (MCE) Integrative and Clinical Endocrinology and Integrative and Clinical Endocrinology and

reproduction (ICER)reproduction (ICER) Cellular, Molecular and Integrative Reproduction Cellular, Molecular and Integrative Reproduction

(CMIR)(CMIR) Pregnancy and Neonatology (PN)Pregnancy and Neonatology (PN) Cellular Aspects of Diabetes and Obesity (CADO)Cellular Aspects of Diabetes and Obesity (CADO) Integrative Physiology of Obesity and Diabetes Integrative Physiology of Obesity and Diabetes

(IPOD)(IPOD) Integrative Nutrition and Metabolic Processes (INMP)Integrative Nutrition and Metabolic Processes (INMP)

MEETING ROSTER MEETING ROSTER CENTER FOR SCIENTIFIC REVIEW ADVISORY COMMITTEE CENTER FOR SCIENTIFIC REVIEW ADVISORY COMMITTEE

Endocrinology, Metabolism, Nutrition & Reproductive Sciences Study Section Boundaries Team Endocrinology, Metabolism, Nutrition & Reproductive Sciences Study Section Boundaries Team APRIL 28 - 30, 2002 APRIL 28 - 30, 2002

CHAIRPERSONCHAIRPERSON

LORIAUX, LYNN D., MD, PHD LORIAUX, LYNN D., MD, PHD PROFESSOR AND CHAIRMAN PROFESSOR AND CHAIRMAN DEPARTMENT OF MEDICINE DEPARTMENT OF MEDICINE OREGON HEALTH SCIENCES UNIVERSITY OREGON HEALTH SCIENCES UNIVERSITY PORTLAND, OR 97201 PORTLAND, OR 97201

MEMBERS MEMBERS BIGGERS, JOHN D., DSC, PHDBIGGERS, JOHN D., DSC, PHD PROFESSOR OF CELL BIOLOGY PROFESSOR OF CELL BIOLOGY DEPARTMENT OF CELL BIOLOGY DEPARTMENT OF CELL BIOLOGY HARVARD MEDICAL SCHOOL HARVARD MEDICAL SCHOOL BOSTON, MA 02115 BOSTON, MA 02115

BROWNLEE, MICHAEL A., MD BROWNLEE, MICHAEL A., MD ANITA & JACK SALTZ PROFESSOR OF DIABETES ANITA & JACK SALTZ PROFESSOR OF DIABETES RESEARCH RESEARCH DEPARTMENT OF MEDICINE & PATHOLOGY DEPARTMENT OF MEDICINE & PATHOLOGY ALBERT EINSTEIN COLLEGE OF MEDICINE ALBERT EINSTEIN COLLEGE OF MEDICINE BRONX, NY 10461 BRONX, NY 10461

CHAIT, ALAN, MD CHAIT, ALAN, MD EDWIN L. BIERMAN PROFESSOR OF MEDICINE EDWIN L. BIERMAN PROFESSOR OF MEDICINE HEAD, DIVISION OF METABOLISM, HEAD, DIVISION OF METABOLISM, ENDCRIONOLOGY ENDCRIONOLOGY & NUTRITION & NUTRITION DEPARTMENT OF MEDICINE DEPARTMENT OF MEDICINE UNIVERSITY OF WASHINGTON UNIVERSITY OF WASHINGTON SEATTLE, WA 98195 SEATTLE, WA 98195

CHIN, WILLIAM W., MD CHIN, WILLIAM W., MD VICE PRESIDENT, GENE REGULATION, BONE VICE PRESIDENT, GENE REGULATION, BONE & INFLAMMATION & INFLAMMATION RESEARCH, CLINICAL INVESTIGATION AND RESEARCH, CLINICAL INVESTIGATION AND PLATFORM BIOLOGY PLATFORM BIOLOGY LILLY RESEARCH LABORATORIES LILLY RESEARCH LABORATORIES LILLY CORPORATE CENTER LILLY CORPORATE CENTER INDIANAPOLIS, IN 46285 INDIANAPOLIS, IN 46285

COUSINS, ROBERT J., PHD COUSINS, ROBERT J., PHD BOSTON FAMILY PROFESSOR OF HUMAN NUTRITION BOSTON FAMILY PROFESSOR OF HUMAN NUTRITION DIRECTOR, CENTER FOR NUTRITIONAL SCIENCES DIRECTOR, CENTER FOR NUTRITIONAL SCIENCES FOOD SCIENCE & HUMAN NUTRITION DEPARTMENT FOOD SCIENCE & HUMAN NUTRITION DEPARTMENT UNIVERSITY OF FLORIDA UNIVERSITY OF FLORIDA GAINESVILLE, FL 32611 GAINESVILLE, FL 32611

HILL, JAMES O., PHD HILL, JAMES O., PHD PROFESSOR PROFESSOR DEPARTMENT OF PEDIATRICS DEPARTMENT OF PEDIATRICS DIRECTOR, CLINICAL NUTRITION RESEARCH DIRECTOR, CLINICAL NUTRITION RESEARCH CENTER FOR HUMAN NUTRITION CENTER FOR HUMAN NUTRITION UNIVERSITY OF COLORADO HEALTH SCIENCES UNIVERSITY OF COLORADO HEALTH SCIENCES CENTER CENTER DENVER, CO 80262 DENVER, CO 80262

KAHN, BARBARA B., MD KAHN, BARBARA B., MD CHIEF, DIVISION OF ENDOCRINOLOGY, CHIEF, DIVISION OF ENDOCRINOLOGY, DIABETES & METABOLISM DIABETES & METABOLISM BETH ISRAEL DEACONESS MEDICAL CENTER BETH ISRAEL DEACONESS MEDICAL CENTER PROFESSOR OF MEDICINE PROFESSOR OF MEDICINE HARVARD MEDICAL SCHOOL HARVARD MEDICAL SCHOOL BOSTON, MA 02215 BOSTON, MA 02215

KING, JANET C., PHD KING, JANET C., PHD DIRECTOR AND PROFESSOR OF NUTRITION DIRECTOR AND PROFESSOR OF NUTRITION WESTERN HUMAN NUTRITION RESEARCH CENTER WESTERN HUMAN NUTRITION RESEARCH CENTER UNIVERSITY OF CALIFORNIA UNIVERSITY OF CALIFORNIA DAVIS, CA 95616 DAVIS, CA 95616

LEIBEL, RUDOLPH L., MD LEIBEL, RUDOLPH L., MD PROFESSOR PROFESSOR HEAD, DIVISION OF MOLECULAR GENETICS HEAD, DIVISION OF MOLECULAR GENETICS COLUMBIA UNIVERSITY COLLEGE OF COLUMBIA UNIVERSITY COLLEGE OF PHYSICIANS & SURGEONS PHYSICIANS & SURGEONS NEW YORK, NY 10032 NEW YORK, NY 10032

MEANS, ANTHONY R., PHD MEANS, ANTHONY R., PHD NANALINE H. DUKE PROFESSOR & CHAIRMAN NANALINE H. DUKE PROFESSOR & CHAIRMAN DEPARTMENT OF PHARMACOLOGY & CANCER BIOLOGY DEPARTMENT OF PHARMACOLOGY & CANCER BIOLOGY DUKE UNIVERSITY MEDICAL CENTER DUKE UNIVERSITY MEDICAL CENTER DURHAM, NC 27710 DURHAM, NC 27710

NILSON, JOHN H., PHD NILSON, JOHN H., PHD JOHN H. HORD PROFESSOR AND CHAIR JOHN H. HORD PROFESSOR AND CHAIR DEPARTMENT OF PHARMACOLOGY DEPARTMENT OF PHARMACOLOGY SCHOOL OF MEDICINE SCHOOL OF MEDICINE CASE WESTERN RESERVE UNIVERSITY CASE WESTERN RESERVE UNIVERSITY CLEVELAND, OH 44106 CLEVELAND, OH 44106

PHILLIPPE, MARK, MD*PHILLIPPE, MARK, MD* PROFESSOR AND CHAIRMAN PROFESSOR AND CHAIRMAN DEPARTMENT OFOBSTETRICS & GYNECOLOGY DEPARTMENT OFOBSTETRICS & GYNECOLOGY UNIVERSITY OF VERMONT UNIVERSITY OF VERMONT COLLEGE OF MEDICINE COLLEGE OF MEDICINE BURLINGTON, VT 05401 BURLINGTON, VT 05401

RICHARDS, JOANNE S., PHDRICHARDS, JOANNE S., PHD **PROFESSOR PROFESSOR DEPARTMENT OF MOLECULAR & CELLULAR DEPARTMENT OF MOLECULAR & CELLULAR BIOLOGY BIOLOGY BAYLOR COLLEGE OF MEDICINE BAYLOR COLLEGE OF MEDICINE HOUSTON, TX 77030 HOUSTON, TX 77030

RIZZA, ROBERT A., MD RIZZA, ROBERT A., MD PROFESSOR OF MEDICINE PROFESSOR OF MEDICINE CHAIR, DIVISION OF ENDOCRINOLOGY, CHAIR, DIVISION OF ENDOCRINOLOGY, DIABETES, METABOLISM & NUTRITION DIABETES, METABOLISM & NUTRITION MAYO CLINIC MAYO CLINIC ROCHESTER, MN 55905 ROCHESTER, MN 55905

SEMENKOVICH, CLAY F., MD SEMENKOVICH, CLAY F., MD PROFESSOR OF MEDICINE & CELL BIOLOGY & PROFESSOR OF MEDICINE & CELL BIOLOGY & PHYSIOLOGY PHYSIOLOGY DEPARTMENT OF INTERNAL MEDICINE DEPARTMENT OF INTERNAL MEDICINE WASHINGTON UNIVERSITY IN ST. LOUIS WASHINGTON UNIVERSITY IN ST. LOUIS ST. LOUIS, MO 63110 ST. LOUIS, MO 63110 STEINER, DONALD F., MD STEINER, DONALD F., MD PROFESSOR & SENIOR INVESTIGATOR PROFESSOR & SENIOR INVESTIGATOR DEPARTMENT OF BIOHEMISTRY & DEPARTMENT OF BIOHEMISTRY & MOLECULAR BIOLOGY MOLECULAR BIOLOGY UNIVERSITY OF CHICAGO UNIVERSITY OF CHICAGO CHICAGO, IL 60637 CHICAGO, IL 60637

STRAUSS, JEROME F. III, MD, PHD **STRAUSS, JEROME F. III, MD, PHD ** LUIGI MASTROIANNI JR. PROFESSOR LUIGI MASTROIANNI JR. PROFESSOR DIRECTOR, CENTER FOR RESEARCH ON DIRECTOR, CENTER FOR RESEARCH ON REPRODUCTIVES & WOMEN'S HEALTH REPRODUCTIVES & WOMEN'S HEALTH ASSOCIATE CHAIRMAN ASSOCIATE CHAIRMAN DEPARTMENT OF OBSTETRICS AND GYNECOLOGY DEPARTMENT OF OBSTETRICS AND GYNECOLOGY UNIVERSITY OF PENNSYLVANIA UNIVERSITY OF PENNSYLVANIA PHILADELPHIA, PA 19104 PHILADELPHIA, PA 19104

TALAMANTES, FRANK J. JR, PHD TALAMANTES, FRANK J. JR, PHD VICE PROVOST AND DEAN OF THE GRADUATE DIVISION VICE PROVOST AND DEAN OF THE GRADUATE DIVISION PROFESSOR OF ENDOCRINOLOGY PROFESSOR OF ENDOCRINOLOGY UNIVERSITY OF CALIFORNIA UNIVERSITY OF CALIFORNIA SANTA CRUZ, CA 95064 SANTA CRUZ, CA 95064

VALE, WYLIE W. JR., PHD* VALE, WYLIE W. JR., PHD* PROFESSOR AND HEAD PROFESSOR AND HEAD PEPTIDE BIOLOGY LABORATORIES PEPTIDE BIOLOGY LABORATORIES THE SALK INSTITUTE THE SALK INSTITUTE LA JOLLA, CA 92037LA JOLLA, CA 92037

WEISS, GERSON, MD*WEISS, GERSON, MD* PROFESSOR AND CHAIR PROFESSOR AND CHAIR DEPARTMENT OF OBSTETRICS, GYNECOLOGY DEPARTMENT OF OBSTETRICS, GYNECOLOGY & WOMEN'S HEALTH & WOMEN'S HEALTH UMD-NEW JERSEY MEDICAL SCHOOL UMD-NEW JERSEY MEDICAL SCHOOL NEWARK, NJ 07103 NEWARK, NJ 07103 WHITE, MORRIS F., PHD WHITE, MORRIS F., PHD SENIOR INVESTIGATOR SENIOR INVESTIGATOR JOSLIN DIABETES CENTER JOSLIN DIABETES CENTER HOWARD HUGHES MEDICAL INSTITUTE HOWARD HUGHES MEDICAL INSTITUTE BOSTON, MA 02215 BOSTON, MA 02215

WISE, PHYLLIS M., PHD WISE, PHYLLIS M., PHD PROFESSOR OF NEUROBIOLOGY, PHYSIOLOGY PROFESSOR OF NEUROBIOLOGY, PHYSIOLOGY & BEHAVIOR & BEHAVIOR DEAN OF BIOLOGICAL SCIENCES DEAN OF BIOLOGICAL SCIENCES UNIVERSITY OF CALIFORNIA DAVIS UNIVERSITY OF CALIFORNIA DAVIS DAVIS, CA 95616-8536 DAVIS, CA 95616-8536 ZIRKIN, BARRY R., PHD*ZIRKIN, BARRY R., PHD* PROFESSOR PROFESSOR DEPARTMENT OF BIOCHEMISTRY & MOLECULAR BIOLOGY DEPARTMENT OF BIOCHEMISTRY & MOLECULAR BIOLOGY DIVISION OF REPRODUCTIVE BIOLOGY DIVISION OF REPRODUCTIVE BIOLOGY SCHOOL OF PUBLIC HEALTH SCHOOL OF PUBLIC HEALTH JOHNS HOPKINS UNIVERSITY JOHNS HOPKINS UNIVERSITY BALTIMORE, MD 21205 BALTIMORE, MD 21205

DESIGNATED FEDERAL OFFICIALDESIGNATED FEDERAL OFFICIAL MARTIN, MICHAEL, PHD MARTIN, MICHAEL, PHD DIRECTOR DIRECTOR DIVISION OF PHYSIOLOGICAL SYSTEMS DIVISION OF PHYSIOLOGICAL SYSTEMS CENTER FOR SCIENTIFIC REVIEW CENTER FOR SCIENTIFIC REVIEW BETHESDA, MD 20892 BETHESDA, MD 20892

PROGRAM REPRESENTATIVES PROGRAM REPRESENTATIVES BELLINO, FRANCIS, PHD BELLINO, FRANCIS, PHD BIOLOGY OF AGING PROGRAM BIOLOGY OF AGING PROGRAM NATIONAL INSTITUTE ON AGING , NIHNATIONAL INSTITUTE ON AGING , NIH BETHESDA, MD 20892 BETHESDA, MD 20892

DEPAOLO, LOUIS V., PHD DEPAOLO, LOUIS V., PHD DIRECTOR, REPRODUCTIVE NEUROENDOCRINOLOGY DIRECTOR, REPRODUCTIVE NEUROENDOCRINOLOGY PROGRAM PROGRAM REPRODUCTIVE SCIENCES BRANCH REPRODUCTIVE SCIENCES BRANCH NICHD, NIH NICHD, NIH BETHESDA, MD 20892 BETHESDA, MD 20892

FREEMAN, COLETTE S. PHD FREEMAN, COLETTE S. PHD CHIEF, CANCER CELL BIOLOGY RESEARCH CHIEF, CANCER CELL BIOLOGY RESEARCH DIVISION OF CANCER BIOLOGY DIVISION OF CANCER BIOLOGY NCI, NIHNCI, NIH BETHESDA, MD 20892 BETHESDA, MD 20892

HEINDEL, JERROLD J., PHD HEINDEL, JERROLD J., PHD DIVISION OF EXTRAMURAL RESEARCH & DIVISION OF EXTRAMURAL RESEARCH & TRAINING TRAINING NIEHS, NIHNIEHS, NIH RESEARCH TRIANGLE PARK, NC 27709 RESEARCH TRIANGLE PARK, NC 27709 MARGOLIS, RONALD N., PHD MARGOLIS, RONALD N., PHD SENIOR ADVISOR FOR MOLECULAR ENDOCRINOLOGY SENIOR ADVISOR FOR MOLECULAR ENDOCRINOLOGY DIVISION OF DIABETES, ENDOCRINOLOGY DIVISION OF DIABETES, ENDOCRINOLOGY & KIDNEY DISEASES & KIDNEY DISEASES NIDDK, NIH NIDDK, NIH BETHESDA, MD 20892 BETHESDA, MD 20892

OTHER REVIEW STAFF OTHER REVIEW STAFF KNECHT, MICHAEL, PHD KNECHT, MICHAEL, PHD SCIENTIFIC REVIEW ADMINISTRATOR SCIENTIFIC REVIEW ADMINISTRATOR CENTER FOR SCIENTIFIC REVIEW CENTER FOR SCIENTIFIC REVIEW NIH NIH BETHESDA, MD BETHESDA, MD

Integrative and Clinical Endocrinology Integrative and Clinical Endocrinology and reproduction (ICER)and reproduction (ICER)

Physiology and pathophysiology of endocrine Physiology and pathophysiology of endocrine systems, and clinical endocrine and systems, and clinical endocrine and reproductive science investigations (Novel reproductive science investigations (Novel hormone based therapies);hormone based therapies);

Adaptation and response to environmental Adaptation and response to environmental stress and homeostatic challenge, including stress and homeostatic challenge, including endocrine disruptors and xenobiotics;endocrine disruptors and xenobiotics;

Genetics and genomics, growth, Genetics and genomics, growth, development, and aging; development, and aging;

Neuroendocrinology, neuroendocrine control Neuroendocrinology, neuroendocrine control of reproductive processes;of reproductive processes;

Interactions with the cardiovascular, GI and Interactions with the cardiovascular, GI and immune systems, comparative edocrinologyimmune systems, comparative edocrinology

Cellular, Molecular and Integrative Cellular, Molecular and Integrative Reproduction (CMIR)Reproduction (CMIR)

Biology of germ cells and gametes, early Biology of germ cells and gametes, early events in conception, and embryo events in conception, and embryo development (including embryonic stem development (including embryonic stem cells until the stage of implantation);cells until the stage of implantation);

Reproductive toxicology; gonadal function; Reproductive toxicology; gonadal function; puberty; male and female reproductive puberty; male and female reproductive aging;aging;

Male and female reproductive tracts and Male and female reproductive tracts and their disorders;their disorders;

Research on infertility, conception, Research on infertility, conception, gynecology and adrologygynecology and adrology

Molecular, cellular, systems and integrative Molecular, cellular, systems and integrative aspects of reproductive biologyaspects of reproductive biology

Pregnancy and Neonatology (PN)Pregnancy and Neonatology (PN)

All aspects of intrauterine mammalian All aspects of intrauterine mammalian development from implantation through development from implantation through pregnancy, parturition and the neonatal period.pregnancy, parturition and the neonatal period.

Normal physiology of pregnancy, parturition and Normal physiology of pregnancy, parturition and postpartum period, disorders of pregnancy, postpartum period, disorders of pregnancy, neonatal development and diseases of the neonatal development and diseases of the newborn.newborn.

Immunology of pregnancy, maternal nutrition, the Immunology of pregnancy, maternal nutrition, the effects of pharmaceuticals, xenobiotic agents, effects of pharmaceuticals, xenobiotic agents, and environmental toxicants on pregnancy;and environmental toxicants on pregnancy;

Placental endocrinology and function;Placental endocrinology and function; Clinical and basic genetics, molecular biology, Clinical and basic genetics, molecular biology,

cellular and organ physiology, and integrative cellular and organ physiology, and integrative biology.biology.

Implementation ProcessImplementation Process

Establishing the roster of review panels: Establishing the roster of review panels: Invited current chartered members to Invited current chartered members to select for service in the new EMNR IRG select for service in the new EMNR IRG study sections or other IRGsstudy sections or other IRGs

Resolution of shared interest issues Resolution of shared interest issues

Implementation Process Implementation Process (cont’d.)(cont’d.)

Finalized the EMNR IRG Descriptions and Finalized the EMNR IRG Descriptions and Provisional RostersProvisional Rosters

Description and Provisional Rosters were Description and Provisional Rosters were posted on the CSR Web on 12/23/2003posted on the CSR Web on 12/23/2003

Description: Description: www.csr.nih.gov/irgdesc.htmwww.csr.nih.gov/irgdesc.htm

Rosters: Rosters: ww.csr.nih.gov/Roster_proto/sectionsl.aspww.csr.nih.gov/Roster_proto/sectionsl.asp

How to direct applications How to direct applications to appropriate study to appropriate study section section EMNR IRG study section descriptions (visit EMNR IRG study section descriptions (visit

the CSR website)the CSR website)

Provisional Rosters of study sections Provisional Rosters of study sections (website)(website)

SRAs or and Institute program staffSRAs or and Institute program staff

Cover letter (indicate the content area of the Cover letter (indicate the content area of the application and suggest several possible application and suggest several possible study sectionsstudy sections

Ongoing and Future EffortsOngoing and Future Efforts

Outreach efforts will be intensified to show Outreach efforts will be intensified to show applicants how to benefit from changes at applicants how to benefit from changes at CSRCSR

Multiple assessments will be made to see Multiple assessments will be made to see how well the new organization functions.how well the new organization functions.

Contacts with the professional societies and Contacts with the professional societies and members of the scientific community will be members of the scientific community will be maintained so CSR can benefit from their maintained so CSR can benefit from their inputinput

CSR will continue its ongoing initiative to CSR will continue its ongoing initiative to conduct Working Group evaluations of each conduct Working Group evaluations of each IRG every 5 yearsIRG every 5 years

Streamlining Streamlining InitiativesInitiatives Electronic Grant Application SubmissionElectronic Grant Application Submission

Self-Referral by InvestigatorSelf-Referral by Investigator

Shorten Time from Submission to AwardShorten Time from Submission to Award

Shorten Re-Submission Time for Revised Shorten Re-Submission Time for Revised ApplicationsApplications

Learn More About CSR’s Learn More About CSR’s ReorganizationReorganization

http://www.csr.nih.gov/review/reorgachttp://www.csr.nih.gov/review/reorgact.aspt.asp