OTIS ANNUAL RESEARCH MEETING JUNE 2010 Vaccines and Medications in Pregnancy Surveillance System (VAMPSS)

OTIS ANNUAL RESEARCH MEETING JUNE 2010

Vaccines and Medications in Pregnancy Surveillance

System (VAMPSS)

Background

VAMPSS is sponsored & coordinated by the American Academy of Allergy Asthma &

Immunology and includes two data collection arms and a standing advisory committee

Prospective registry surveillance: OTISCase-Control Surveillance: Slone Epidemiology

Center at Boston UniversityIndependent advisory committee (biostatistician,

reproductive epidemiologist, consumer representative, CDC, NICHD, NHLBI, NIAID, and AAP)

Purpose

The purpose of VAMPSS is to comprehensively monitor the use and safety of flu vaccines and antiviral medications used to treat or prevent

the flu during pregnancy.

VAMPSS Cohort Study Totals

Group Total Enrolled

Recruitment Goal

Seasonal Flu Vaccine 250 300

H1N1 Vaccine 352 300

Antivirals 34 200

Controls 40 300

Total Cohort 411 1100

Total Enrollment to Date

Total as of June 23, 2010

Enrolled 411

Outcome 236

Live birth 229

Recruitment

Source No. Enrolled

TIS 258

Health-care Professional

82

Self / Other 48

Internet 23

Who Should be Referred?

Essentially all pregnant women.Specifically:Pregnant women who received a flu vaccine

during pregnancy.Pregnant women who were exposed to an

anti-viral medication to treat or prevent the flu during pregnancy.

Non-exposed controls (pregnant women who have not received any flu vaccines during pregnancy or taken any antivirals while pregnant).

Upcoming Projects

Flu Season!!

www.otispregnancy.org