Osteoporosis : Global Problem

Presented by:

AHMED SAVANI

Osteoporosis is nothing but problem with ……

Your BonesThat have become Weak & Porous

4

Why Are Healthy Bones Important?

• Strong bones support us and allow us to move

• Bones are a storehouse for vital minerals

• Strong bones protect our heart, lungs, brain and other organs

10

• After mid-30’s, you begin to slowly lose bone mass.

• Women lose bone mass faster after menopause.

• Men lose bone mass too.

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Generally breaks the bones of the wrist, spine and hip.

Vertebral Fracture Cascade

Somewhere in the World

Studies were made,…In India what found

2003 studies by IOF

ButIn 2013 studies were made again & what the Result they got…were totally unimaginable People suffered by Osteoporosis reached to ……

In most Western countries, the peak incidence of osteoporosis occurs at about 70-80 years of age,

BUT

Osteoporotic Fractures:Comparison with Other Diseases

1996 new cases,all ages184 300

750 000 vertebral

250 000 other sites

250 000forearm

250 000hip

0

500

1000

1500

2000

Osteoporotic Fractures

HeartAttack

Stroke BreastCancer

An

nu

al in

cid

ence

x 1

00

0

1 500 000

Annual incidenceall ages

513 000

annual estimatewomen 29+

228 000

annual estimatewomen 30+

All fractures are Associated With Morbidity

Cooper C, Am J Med, 1997;103(2A):12S-17S

40%

Unable to walk independently

30%

Permanentdisability

20%

Death within one year

80%

Unable to carry out at least one independent activity of daily living

Age/ Getting older Having a family history of osteoporosis Estrogens & testosterone hormone deficiency Female sex After Menopause in Female Low Calcium /Vitamin D Intake Alcohol consumption Smoking Low body weight Long Use of Steroids medication Low sun exposure Poor or lack of exercise Sedentary lifestyle/ Prolonged immobilisation

NAGLI -RAGI

ફણગાવેલા કઠોળ (મગ, મઠ વવ....)

સકૂાાં મેવા (કાજુ, અખરોટ, બદામ, ખજૂર વવ..)

દૂધ અને દૂધની બનાવટો

IOM Report - 2010

Daily vitamin D needs in International Units (IU)

Age

600 IU

200 IU

400 IU

0

100

200

300

400

500

600

up to 50 51-70 over 70

IU

Medications Available for

Post-Menopausal Osteoporosis

• Actonel® (risedronate sodium tablets)

• Didrocal® (etidronate sodium tablets)

• Fosamax® (alendronate sodium tablets)

• Aclasta ® (zolendronate IV)

• Estrogen (some use)

• Evista® (raloxifene HCl)

• Miacalcin® (calcitonin salmon) Nasal Spray

• Forteo (Teriparatide) (sc)

• Consult with your physician to determine what medication may be best for

you

Diagnostic criteria* Classification

T is above or equal to -1 Normal

T is between -1 and -2.5 Osteopenia (low

bone mass)

T is -2.5 or lower Osteoporosis

T is -2.5 or lower + fx = Severe or est.

osteoporosis

*Measured in "T scores." T score indicates the number of standard deviations below or above the average peak bone mass in young adults.

WHO Criteria for Diagnosis of Bone Status

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Vitamin D from sunlight exposure

• Vitamin D is manufactured in your skin following direct exposure to sun.

• Amount varies with time of day, season, latitude and skin pigmentation.

• 10–15 minutes exposure of hands, arms and face 2–3 times/week may be sufficient (depending on skin sensitivity).

• Clothing, sunscreen, window glass and pollution reduce amount produced.

Source: National Osteoporosis Foundation Web site; retrieved July 2005 at http://www.nof.org

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Vitamin D necessary for calcium absorption

• Choose a supplement with vitamin D unless obtaining vitamin D from other sources.

• Follow age group recommendation. Avoid goingover a daily combined total of 2,000 IU or 50 mcg from foodand supplements.

• It’s not necessary to consume calcium and vitamin D at the same time to get the benefit of enhanced calcium absorption.

Vitamin D is like a key that unlocks the doorand lets calciuminto the body.

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Limit calcium to 500 mg at a time

Our bodies can best handle about 500 mg calcium at one time from food and/or supplements.

Spread your calcium sources throughout the day.

500 mg

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Bone Health Building Blocks